Journal Article: Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2
Brennan, Faith H., Jogia, Trisha, Gillespie, Ellen R., Blomster, Linda V., Li, Xaria X., Nowlan, Bianca, Williams, Gail M., Jacobson, Esther, Osborne, Geoff W., Meunier, Frederic A., Taylor, Stephen M., Campbell, Kate E., MacDonald, Kelli P.A., Levesque, Jean-Pierre, Woodruff, Trent M. and Ruitenberg, Marc J. (2019). Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2. JCI Insight, 4 (9) e98254. doi: 10.1172/jci.insight.98254
Journal Article: Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells
Robson, Jonathan P., Remke, Marc, Kool, Marcel, Julian, Elaine, Korshunov, Andrey, Pfister, Stefan M., Osborne, Geoffrey W., Taylor, Michael D., Wainwright, Brandon and Reynolds, Brent A. (2019). Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells. PLoS ONE, 14 (1) e0210665, e0210665. doi: 10.1371/journal.pone.0210665
Journal Article: Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach
Fontaine, Frank R., Goodall, Stephen, Prokop, Jeremy W., Howard, Christopher B., Moustaqil, Mehdi, Kumble, Sumukh, Rasicci, Daniel T., Osborne, Geoffrey W., Gambin, Yann, Sierecki, Emma, Jones, Martina L., Zuegg, Johannes, Mahler, Stephen and Francois, Mathias (2018). Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach. mAbs, 10 (4), 1-11. doi: 10.1080/19420862.2018.1451288
Single Cell Transcriptomic Laboratory
(2016) UQ Major Equipment and Infrastructure
ACRF Facility for Molecular Imaging Agents in Cancer (AFMIAC)
(2015–2022) Australian Cancer Research Foundation
Searching for novel prognostic indicators of survival for glioblastoma patients
(2015–2016) The Wesley-St. Andrew's Research Institute Limited
A brief introduction to neural flow cytometry from a practical perspective
Osborne, Geoffrey W. (2015). A brief introduction to neural flow cytometry from a practical perspective. Neural surface antigens: from basic biology towards biomedical applications. (pp. 15-26) edited by Jan Pruszak. London, United Kingdom: Elsevier. doi: 10.1016/B978-0-12-800781-5.00002-5
Flow cytometry of neural cells
Osborne, Geoffrey W. (2013). Flow cytometry of neural cells. Neural Progenitor Cells: Methods and Protocols. (pp. 135-144) edited by Brent A. Reynolds and Loic P. Deleyrolle. New York, NY, United States: Humana Press. doi: 10.1007/978-1-62703-574-3_12
Recent advances in flow cytometric cell sorting
Osborne, Geoffrey W. (2011). Recent advances in flow cytometric cell sorting. Recent advances in cytometry. Part A: Instrumentation, methods. (pp. 533-556) edited by Zbigniew Darzynkiewicz, Elena Holden, Alberto Orfao, William Telford and Donald Wlodkowic. Maryland Heights, MO, United States: Academic Press. doi: 10.1016/b978-0-12-374912-3.00021-3
Practical considerations for flow cytometric sorting of stem cells
Osborne, Geoffrey W. (2010). Practical considerations for flow cytometric sorting of stem cells. Application of flow cytometry in stem cell research and tissue regeneration. (pp. 13-23) edited by Awtar Krishan, H. Krishnamurthy and Satish Totey. Hoboken, New Jersey: John Wiley & Sons, Inc.. doi: 10.1002/9780470631119.ch2
Brennan, Faith H., Jogia, Trisha, Gillespie, Ellen R., Blomster, Linda V., Li, Xaria X., Nowlan, Bianca, Williams, Gail M., Jacobson, Esther, Osborne, Geoff W., Meunier, Frederic A., Taylor, Stephen M., Campbell, Kate E., MacDonald, Kelli P.A., Levesque, Jean-Pierre, Woodruff, Trent M. and Ruitenberg, Marc J. (2019). Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2. JCI Insight, 4 (9) e98254. doi: 10.1172/jci.insight.98254
Robson, Jonathan P., Remke, Marc, Kool, Marcel, Julian, Elaine, Korshunov, Andrey, Pfister, Stefan M., Osborne, Geoffrey W., Taylor, Michael D., Wainwright, Brandon and Reynolds, Brent A. (2019). Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells. PLoS ONE, 14 (1) e0210665, e0210665. doi: 10.1371/journal.pone.0210665
Fontaine, Frank R., Goodall, Stephen, Prokop, Jeremy W., Howard, Christopher B., Moustaqil, Mehdi, Kumble, Sumukh, Rasicci, Daniel T., Osborne, Geoffrey W., Gambin, Yann, Sierecki, Emma, Jones, Martina L., Zuegg, Johannes, Mahler, Stephen and Francois, Mathias (2018). Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach. mAbs, 10 (4), 1-11. doi: 10.1080/19420862.2018.1451288
Luan, Wei, Hammond, Luke Alexander, Cotter, Edmund, Osborne, Geoffrey William, Alexander, Suzanne Adele, Nink, Virginia, Cui, Xiaoying and Eyles, Darryl Walter (2017). Developmental vitamin D (DVD) deficiency reduces Nurr1 and TH expression in post-mitotic dopamine neurons in rat mesencephalon. Molecular Neurobiology, 55 (3), 2443-2453. doi: 10.1007/s12035-017-0497-3
Targeting membrane proteins for antibody discovery using phage display
Jones, Martina L., Alfaleh, Mohamed A., Kumble, Sumukh, Zhang, Shuo, Osborne, Geoffrey W., Yeh, Michael, Arora, Neetika, Hou, Jeff Jia Cheng, Howard, Christopher B., Chin, David Y. and Mahler, Stephen M. (2016). Targeting membrane proteins for antibody discovery using phage display. Scientific Reports, 6 (1) 26240, 26240. doi: 10.1038/srep26240
Jhaveri, Dhanisha J., O'Keeffe, Imogen, Robinson, Gregory J., Zhao, Qiong-Yi, Zhang, Zong Hong, Nink, Virginia, Narayanan, Ramesh K., Osborne, Geoffrey W., Wray, Naomi R. and Bartlett, Perry F. (2015). Purification of neural precursor cells reveals the presence of distinct, stimulus-specific subpopulations of quiescent precursors in the adult mouse hippocampus. Journal of Neuroscience, 35 (21), 8132-8144. doi: 10.1523/JNEUROSCI.0504-15.2015
A novel flow cytometric method to assess inflammasome formation
Sester, David P., Thygesen, Sara J., Sagulenko, Vitaliya, Vajjhala, Parimala R., Cridland, Jasmyn A., Vitak, Nazarii, Chen, Kaiwen W., Osborne, Geoffrey W., Schroder, Kate and Katryn J. Stacey (2015). A novel flow cytometric method to assess inflammasome formation. The Journal of Immunology, 194 (1), 455-462. doi: 10.4049/jimmunol.1401110
Development of a novel cell sorting method that samples population diversity in flow cytometry
Osborne, Geoffrey W., Andersen, Stacey B. and Battye, Francis L. (2015). Development of a novel cell sorting method that samples population diversity in flow cytometry. Cytometry Part A, 87 (11), 1047-1051. doi: 10.1002/cyto.a.22678
Absolute counting of neutrophils in whole blood using flow cytometry
Brunck, Marion E. G., Andersen, Stacey B., Timmins, Nicholas E., Osborne, Geoffrey W. and Nielsen, Lars K. (2014). Absolute counting of neutrophils in whole blood using flow cytometry. Cytometry Part A, 85 (12), 1057-1064. doi: 10.1002/cyto.a.22503
Effect of a hemiuroid trematode on the hemocyte immune parameters of the cockle Anadara trapezia
Dang, Cécile, Cribb, Thomas H., Osborne, Geoffrey, Kawasaki, Minami, Bedin, Anne-Sophie and Barnes, Andrew C. (2013). Effect of a hemiuroid trematode on the hemocyte immune parameters of the cockle Anadara trapezia. Fish and Shellfish Immunology, 35 (3), 951-956. doi: 10.1016/j.fsi.2013.07.010
A novel fluorescent reporter CDy1 enriches for neural stem cells derived from the murine brain
Vukovic, Jana, Bedin, Anne-Sophie, Bartlett, Perry F. and Osborne, Geoffrey W. (2013). A novel fluorescent reporter CDy1 enriches for neural stem cells derived from the murine brain. Stem Cells and Development, 22 (16), 2341-2345. doi: 10.1089/scd.2012.0660
Glioma surgical aspirate: a viable source of tumor tissue for experimental research
Day, Bryan W., Stringer, Brett W., Wilson, John, Jeffree, Rosalind L., Jamieson, Paul R., Ensbey, Kathleen S., Bruce, Zara C., Inglis, Po, Allan, Suzanne, Winter, Craig, Tollesson, Gert, Campbell, Scott, Lucas, Peter, Findlay, Wendy, Kadrian, David, Johnson, David, Robertson, Thomas, Johns, Terrance G., Bartlett, Perry F., Osborne, Geoffrey W. and Boyd, Andrew W. (2013). Glioma surgical aspirate: a viable source of tumor tissue for experimental research. Cancers, 5 (2), 357-371. doi: 10.3390/cancers5020357
EphA3 Maintains Tumorigenicity and Is a Therapeutic Target in Glioblastoma Multiforme
Day, Bryan W., Stringer, Brett W., Al-Ejeh, Fares, Ting, Michael J., Wilson, John, Ensbey, Kathleen S., Jamieson, Paul R., Bruce, Zara C., Lim, Yi Chieh, Offenhauser, Carolin, Charmsaz, Sara, Cooper, Leanne T., Ellacott, Jennifer K., Harding, Angus, Leveque, Lucie, Inglis, Po, Allan, Suzanne, Walker, David G., Lackmann, Martin, Osborne, Geoffrey, Khanna, Kum Kum, Reynolds, Brent A., Lickliter, Jason D. and Boyd, Andrew W. (2013). EphA3 Maintains Tumorigenicity and Is a Therapeutic Target in Glioblastoma Multiforme. Cancer Cell, 23 (2), 238-248. doi: 10.1016/j.ccr.2013.01.007
Prowse, Andrew B. J., Chong, Fenny, Elliott, David A., Elefanty, Andrew G., Stanley, Edouard G., Gray, Peter P., Munro, Trent P. and Osborne, Geoffrey W. (2012). Analysis of Mitochondrial Function and Localisation during Human Embryonic Stem Cell Differentiation In Vitro. PLoS One, 7 (12) e52214, e52214-1-e52214-10. doi: 10.1371/journal.pone.0052214
Pelekanos, Rebecca A., Li, Joan, Gongora, Milena, Chandrakanthan, Vashe, Scown, Janelle, Suhaimi, Norseha, Brooke, Gary, Christensen, Melinda E., Doan, Tram, Rice, Alison M., Osborne, Geoffrey W., Grimmond, Sean M., Harvey, Richard P., Atkinson, Kerry and Little, Melissa H. (2012). Comprehensive transcriptome and immunophenotype analysis of renal and cardiac MSC-like populations supports strong congruence with bone marrow MSC despite maintenance of distinct identities (vol 8, pg 58, 2012). Stem Cell Research, 9 (1), 58-58. doi: 10.1016/j.scr.2012.02.003
Pelekanos, Rebecca A., Li, Joan, Gongora, Milena, Chandrakanthan, Vashe, Scown, Janelle, Suhaimi, Norseha, Gary Brooke, Christensen, Melinda E., Doan, Tram, Rice, Alison M., Osborne, Geoffrey W., Grimmond, Sean M., Harvey, Richard P., Atkinson, Kerry and Little, Melissa H. (2012). Comprehensive transcriptome and immunophenotype analysis of renal and cardiac MSC-like populations supports strong congruence with bone marrow MSC despite maintenance of distinct identities. Stem Cell Research, 8 (1), 58-73. doi: 10.1016/j.scr.2011.08.003
Purification of immature neuronal cells from neural stem cell progeny
Azari, Hassan, Osborne, Geoffrey W., Yasuda, Takahiro, Golmohammadi, Mohammed G., Rahman, Maryam, Deleyroll, Loic P., Esfandiari, Ebrahim, Adams, David J., Scheffler, Bjorn, Steindler, Dennis A. and Reynolds, Brent A. (2011). Purification of immature neuronal cells from neural stem cell progeny. PLoS One, 6 (6) e20941, e20941-13053. doi: 10.1371/journal.pone.0020941
Evidence for label-retaining tumour-initiating cells in human glioblastoma
Deleyrolle, Loic P., Harding, Angus, Cato, Kathleen, Siebzehnrubl, Florian A., Rahman, Maryam, Azari, Hassan, Olson, Sarah, Gabrielli, Brian, Osborne, Geoffrey, Vescovi, Angelo and Reynolds, Brent A. (2011). Evidence for label-retaining tumour-initiating cells in human glioblastoma. Brain, 134 (5), 1331-1343. doi: 10.1093/brain/awr081
A method of quantifying cell sorting yield in "Real time"
Osborne, Geoffrey W. (2010). A method of quantifying cell sorting yield in "Real time". Cytometry Part A, 77A (10), 983-989. doi: 10.1002/cyto.a.20950
Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response
Mooney, Jane E., Rolfe, Barbara E., Osborne, Geoffrey W., Sester, David P., van Rooijen, Nico, Campbell, Gordon R., Hume, David A. and Campbell, Julie H. (2010). Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response. American Journal of Pathology, 176 (1), 369-380. doi: 10.2353/ajpath.2010.090545
Prowse, ABJ, Wilson, J, Osborne, GW, Gray, PP and Wolvetang, EJ (2009). Multiplexed Staining of Live Human Embryonic Stem Cells for Flow Cytometric Analysis of Pluripotency Markers. Stem Cells and Development, 18 (8), 1135-1139. doi: 10.1089/scd.2009.0080
p75 neurotrophin receptor regulates basal and fluoxetine-stimulated hippocampal neurogenesis
Colditz, Michael J., Catts, Vibeke S., Al-menhali, Noura, Osborne, Geoffrey W., Bartlett, Perry F. and Coulson, Elizabeth J. (2009). p75 neurotrophin receptor regulates basal and fluoxetine-stimulated hippocampal neurogenesis. Experimental Brain Research, 200 (2), 161-167. doi: 10.1007/s00221-009-1947-6
Gilbert, Daniel, Wilson, John C., Nink, Virginia, Lynch, Joseph W. and Osborne, Geoffrey W. (2009). Multiplexed labeling of viable cells for high-throughput analysis of glycine receptor function using flow cytometry. Cytometry Part A, 75A (5), 440-449. doi: 10.1002/cyto.a.20703
Crouch, MF, Osborne, GW and Willard, FS (2000). The GTP-binding protein G(i alpha) translocates to kinetochores and regulates the M-G(1) cell cycle transition of Swiss 3T3 cells. Cellular Signalling, 12 (3), 153-163. doi: 10.1016/S0898-6568(99)00080-7
Luan, W., Alexander, S., Osborne, G., Nink, V., Cui, X. and Eyles, D. (2015). Histo-cytometric analysis of prenatal mesencephalic dopaminergic terminal specification based on NURR1 and tyrosine hydroxylase. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1111/jnc.13188
Norepinephrine stimulates a distinct precursor population in the adult hippocampus
Jhaveri, Dhanisha, Newcombe, Estella, Nink, Virginia, Osborne, Geoffrey, Vaidya, Vidita and Bartlett, Perry (2012). Norepinephrine stimulates a distinct precursor population in the adult hippocampus. 19th Biennial Meeting of the International-Society-for-Developmental-Neuroscience (ISDN), Mumbai, India, 11-14 January 2012. Kidlington, Oxford, United Kingdom: Pergamon. doi: 10.1016/j.ijdevneu.2012.03.332
A frequency based method for sorting in flow cytometers
Osborne, G. and Ericksson, G. B. (2006). A frequency based method for sorting in flow cytometers. Stem Cells in the Age of Fluorescence Technology, Goldcoast, Queensland, Australia, November, 6-9, 2005. Hoboken: Wiley-Liss.
Recovery of sorted samples at given combinations of deflection plate voltage and droplet charge
Nink, V. and Osborne, G. (2006). Recovery of sorted samples at given combinations of deflection plate voltage and droplet charge. 7th Samuel A Latt Conference on Stem Cells in the Age of Fluorescence Technology, Gold Coast, Queensland, Australia, 6-9 November, 2005. Hoboken: Wiley-Liss. doi: 10.1002/cyto.a.20264
Accurate cell sorting and positioning studies
Osborne, G. W. (2004). Accurate cell sorting and positioning studies. 27th Annual Meeting of the Australasian Flow Cytometry Group, Adelaide Convention Centre, 12-16 December 2004. Adelaide Australia: Australasian Flow Cytometry Group.
Willard, FS, Osborne, GW and Crouch, MF (2000). The GTP-binding protein Gi alpha 2 translocates to kinetochores and regulates the M-G1 transition of Swiss 3T3 cells..
Nitric Oxide and Malarial Immunosuppression
Rockett, KA, Awburn, MM, Rockett, EJ, Cowden, WB, Osborne, GW, Rolph, MS and Clark, IA (1994). Nitric Oxide and Malarial Immunosuppression. 3rd International Meeting on the Biology of Nitric Oxide, Cologne Germany, Oct 04-06, 1993.
Single Cell Transcriptomic Laboratory
(2016) UQ Major Equipment and Infrastructure
ACRF Facility for Molecular Imaging Agents in Cancer (AFMIAC)
(2015–2022) Australian Cancer Research Foundation
Searching for novel prognostic indicators of survival for glioblastoma patients
(2015–2016) The Wesley-St. Andrew's Research Institute Limited
(2011–2013) UQ FirstLink Scheme
Identifying biomarkers for MND using flow cytometry.
(2009–2010) Motor Neurone Disease Research Institute of Australia Inc