The University of Queensland

Microbioreactor techniques for the production and spectroscopic characterization of microbial peptides

Khalil, Zeinab G., Salim, Angela A. and Capon, Robert J. (2020). Microbioreactor techniques for the production and spectroscopic characterization of microbial peptides. Peptide synthesis: methods and protocols. (pp. 303-322) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_21

Cholesterol as an inbuilt immunoadjuvant for a lipopeptide vaccine against group A Streptococcus infection

Alharbi, Nedaa, Shalash, Ahmed O., Koirala, Prashamsa, Boer, Jennifer C., Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2024). Cholesterol as an inbuilt immunoadjuvant for a lipopeptide vaccine against group A Streptococcus infection. Journal of Colloid and Interface Science, 663, 43-52. doi: 10.1016/j.jcis.2024.02.134

Pullenvalenes A–D: Nitric Oxide-Mediated Transcriptional Activation (NOMETA) Enables Discovery of Triterpene Aminoglycosides from Australian Termite Nest-Derived Fungi

Dewa, Amila Agampodi, Khalil, Zeinab G., Hussein, Waleed M., Jin, Shengbin, Wang, Yanan, Cruz-Morales, Pablo and Capon, Robert J. (2024). Pullenvalenes A–D: Nitric Oxide-Mediated Transcriptional Activation (NOMETA) Enables Discovery of Triterpene Aminoglycosides from Australian Termite Nest-Derived Fungi. Journal of Natural Products. doi: 10.1021/acs.jnatprod.3c01233

Tepuazines A–E: Phenazine Glycosides from a Venezuelan Quartz-Rich (Tepui) Cave Soil-Derived <i>Streptomyces virginiae</i> CMB-CA091

Kankanamge, Sarani, Khalil, Zeinab G. and Capon, Robert J. (2024). Tepuazines A–E: Phenazine Glycosides from a Venezuelan Quartz-Rich (Tepui) Cave Soil-Derived Streptomyces virginiae CMB-CA091. Journal of Natural Products. doi: 10.1021/acs.jnatprod.4c00042

Polymeric nanoparticles as oral and intranasal peptide vaccine delivery systems: the role of shape and conjugation

Koirala, Prashamsa, Shalash, Ahmed O., Chen, Sung-Po R., Faruck, Mohammad O., Wang, Jingwen, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2024). Polymeric nanoparticles as oral and intranasal peptide vaccine delivery systems: the role of shape and conjugation. Vaccines, 12 (2) 198, 1-14. doi: 10.3390/vaccines12020198

Jugiones A–D: Antibacterial Xanthone–Anthraquinone Heterodimers from Australian Soil-Derived Penicillium shearii CMB-STF067

Sritharan, Thulasi, Salim, Angela A., Khalil, Zeinab G. and Capon, Robert J. (2024). Jugiones A–D: Antibacterial Xanthone–Anthraquinone Heterodimers from Australian Soil-Derived Penicillium shearii CMB-STF067. Antibiotics, 13 (1) ARTN 97, 97. doi: 10.3390/antibiotics13010097

Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011

Salim, Angela A., Hussein, Waleed M., Dewapriya, Pradeep, Hoang, Huy N., Zhou, Yahao, Samarasekera, Kaumadi, Khalil, Zeinab G., Fairlie, David P. and Capon, Robert J. (2023). Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011. Marine Drugs, 21 (9) 487, 487. doi: 10.3390/md21090487

Editorial: Advances in biotechnological applications of extreme microorganisms

Núñez-Montero, Kattia, Barrientos, Leticia, Khalil, Zeinab G. and Lo Giudice, Angelina (2023). Editorial: Advances in biotechnological applications of extreme microorganisms. Frontiers in Microbiology, 14 1276435, 1-2. doi: 10.3389/fmicb.2023.1276435

Activity relationship of poly(ethylenimine)-based liposomes as group A Streptococcus vaccine delivery systems

Jin, Shengbin, Zhang, Jiahui, Nahar, Ummey J., Huang, Wenbin, Alharbi, Nedaa A., Shalash, Ahmed O., Koirala, Prashamsa, Yang, Jieru, Kiong, Jolynn J. E., Khalil, Zeinab G., Capon, Robert J., Stephenson, Rachel J., Skwarczynski, Mariusz, Toth, Istvan and Hussein, Waleed M. (2023). Activity relationship of poly(ethylenimine)-based liposomes as group A Streptococcus vaccine delivery systems. ACS Infectious Diseases, 9 (8), 1570-1581. doi: 10.1021/acsinfecdis.3c00159

Total syntheses of favolasins A, E, G and K, polyketides isolated from cultures of the Basidiomycetes fungi Favolaschia sp . BCC 18686 and Favolaschia calocera BCC 36684

Sheng, Bingbing, Lan, Ping, Kiong, Jolynn, Khalil, Zeinab G., Capon, Robert J. and Banwell, Martin G. (2023). Total syntheses of favolasins A, E, G and K, polyketides isolated from cultures of the Basidiomycetes fungi Favolaschia sp . BCC 18686 and Favolaschia calocera BCC 36684. Chinese Journal of Chemistry, 41 (12), 1450-1464. doi: 10.1002/cjoc.202200822

The development of surface-modified liposomes as an intranasal delivery system for group A Streptococcus vaccines

Yang, Jieru, Boer, Jennifer C., Khongkow, Mattaka, Phunpee, Sarunya, Khalil, Zeinab G., Bashiri, Sahra, Deceneux, Cyril, Goodchild, Georgia, Hussein, Waleed M., Capon, Robert J., Ruktanonchai, Uracha, Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2023). The development of surface-modified liposomes as an intranasal delivery system for group A Streptococcus vaccines. Vaccines, 11 (2) 305. doi: 10.3390/vaccines11020305

Noonindoles G–L: Indole diterpene glycosides from the Australian marine-derived fungus Aspergillus noonimiae CMB-M0339

Kankanamge, Sarani, Khalil, Zeinab G., Sritharan, Thulasi and Capon, Robert J. (2023). Noonindoles G–L: Indole diterpene glycosides from the Australian marine-derived fungus Aspergillus noonimiae CMB-M0339. Journal of Natural Products, 86 (3), 508-516. doi: 10.1021/acs.jnatprod.2c01024

Polymeric nanoparticles as a self‐adjuvanting peptide vaccine delivery system: the role of shape

Koirala, Prashamsa, Chen, Sung‐Po R., Boer, Jennifer C., Khalil, Zeinab G., Deceneux, Cyril, Goodchild, Georgia, Lu, Lantian, Faruck, Mohammad Omer, Shalash, Ahmed O., Bashiri, Sahra, Capon, Robert J., Hussein, Waleed M., Monteiro, Michael J., Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2023). Polymeric nanoparticles as a self‐adjuvanting peptide vaccine delivery system: the role of shape. Advanced Functional Materials, 33 (12) 2209304, 2209304. doi: 10.1002/adfm.202209304

Polyphenylalanine as a self-adjuvanting delivery system for peptide-based vaccines: the role of peptide conformation

Skwarczynski, Mariusz, Zhao, Guangzu, Ozberk, Victoria, Giddam, Ashwini Kumar, Khalil, Zeinab G., Pandey, Manisha, Hussein, Waleed M., Nevagi, Reshma J., Batzloff, Michael R., Capon, Robert J., Good, Michael F. and Toth, Istvan (2023). Polyphenylalanine as a self-adjuvanting delivery system for peptide-based vaccines: the role of peptide conformation. Australian Journal of Chemistry, 76 (8), 429-436. doi: 10.1071/ch22167

Noonindoles A–F: Rare indole diterpene amino acid conjugates from a marine-derived fungus, Aspergillus noonimiae CMB-M0339

Kankanamge, Sarani, Khalil, Zeinab G., Bernhardt, Paul V. and Capon, Robert J. (2022). Noonindoles A–F: Rare indole diterpene amino acid conjugates from a marine-derived fungus, Aspergillus noonimiae CMB-M0339. Marine Drugs, 20 (11) 698, 1-16. doi: 10.3390/md20110698

Development of Multilayer Nanoparticles for the Delivery of Peptide-Based Subunit Vaccine against Group A Streptococcus

Kiong, Jolynn, Nahar, Ummey Jannatun, Jin, Shengbin, Shalash, Ahmed O., Zhang, Jiahui, Koirala, Prashamsa, Khalil, Zeinab G., Capon, Robert J., Skwarczynski, Mariusz, Toth, Istvan and Hussein, Waleed M. (2022). Development of Multilayer Nanoparticles for the Delivery of Peptide-Based Subunit Vaccine against Group A Streptococcus. Pharmaceutics, 14 (10) 2151, 1-12. doi: 10.3390/pharmaceutics14102151

Poly(hydrophobic amino acids) and liposomes for delivery of vaccine against Group A Streptococcus

Azuar, Armira, Madge, Harrison Y. R., Boer, Jennifer C., Gonzalez Cruz, Jazmina L., Wang, Jingwen, Khalil, Zeinab G., Deceneux, Cyril, Goodchild, Georgia, Yang, Jieru, Koirala, Prashamsa, Hussein, Waleed M., Capon, Robert J., Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2022). Poly(hydrophobic amino acids) and liposomes for delivery of vaccine against Group A Streptococcus. Vaccines, 10 (8) 1212, 1-14. doi: 10.3390/vaccines10081212

Structure revision of penipacids A–E reveals a putative new cryptic natural product, N-aminoanthranilic acid, with potential as a transcriptional regulator of silent secondary metabolism

Khalil, Zeinab G., Kankanamge, Sarani and Capon, Robert J. (2022). Structure revision of penipacids A–E reveals a putative new cryptic natural product, N-aminoanthranilic acid, with potential as a transcriptional regulator of silent secondary metabolism. Marine Drugs, 20 (6) 339. doi: 10.3390/md20060339

Glenthmycins A–M: macrocyclic spirotetronate polyketide antibacterials from the Australian pasture plant-derived Streptomyces sp. CMB-PB041

Wu, Taizong, Salim, Angela A., Khalil, Zeinab G., Bernhardt, Paul V. and Capon, Robert J. (2022). Glenthmycins A–M: macrocyclic spirotetronate polyketide antibacterials from the Australian pasture plant-derived Streptomyces sp. CMB-PB041. Journal of Natural Products, 85 (6), 1641-1657. doi: 10.1021/acs.jnatprod.2c00444

Chrysosporazines revisited: regioisomeric phenylpropanoid piperazine p-glycoprotein inhibitors from Australian marine fish-derived fungi

Agampodi Dewa, Amila, Khalil, Zeinab G., Elbanna, Ahmed H. and Capon, Robert J. (2022). Chrysosporazines revisited: regioisomeric phenylpropanoid piperazine p-glycoprotein inhibitors from Australian marine fish-derived fungi. Molecules, 27 (10) 3172, 3172. doi: 10.3390/molecules27103172

Metarhizides A–C and metarhizosides A–B: PKS-NRPS macrolides and aromatic glycosides from an Australian fish gut-derived fungus, Metarhizium sp. CMB-F624

Mohamed, Osama G., Khalil, Zeinab G., Santiago, Viviene and Capon, Robert J. (2022). Metarhizides A–C and metarhizosides A–B: PKS-NRPS macrolides and aromatic glycosides from an Australian fish gut-derived fungus, Metarhizium sp. CMB-F624. Tetrahedron, 113 132759, 1-8. doi: 10.1016/j.tet.2022.132759

Structure-activity relationship of lipid, cyclic peptide and antigen rearrangement of physically mixed vaccines

Huang, Wenbin, Madge, Harrison Y. R., Zhang, Jiahui, Gilmartin, Lachlan, Hussein, Waleed M., Khalil, Zeinab G., Koirala, Prashamsa, Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2022). Structure-activity relationship of lipid, cyclic peptide and antigen rearrangement of physically mixed vaccines. International Journal of Pharmaceutics, 617 121614, 1-12. doi: 10.1016/j.ijpharm.2022.121614

Isolation and agricultural potential of penicillic acid against citrus canker

Vieira, Gabrielle, Khalil², Zeinab G., Capon, Robert J., Sette, Lara D., Ferreira, Henrique and Sass, Daiane C. (2022). Isolation and agricultural potential of penicillic acid against citrus canker. Journal of Applied Microbiology, 132 (4), 3081-3088. doi: 10.1111/jam.15413

Glenthenamines A–F: enamine pyranonaphthoquinones from the Australian pasture plant derived Streptomyces sp. CMB-PB042

Wu, Taizong, Salim, Angela A., Cui, Hui, Khalil, Zeinab G., Bernhardt, Paul V. and Capon, Robert J. (2022). Glenthenamines A–F: enamine pyranonaphthoquinones from the Australian pasture plant derived Streptomyces sp. CMB-PB042. Journal of Natural Products, 85 (2) acs.jnatprod.1c00821, 337-344. doi: 10.1021/acs.jnatprod.1c00821

Neochrysosporazines: precursor-directed biosynthesis defines a marine-derived fungal natural product p-glycoprotein inhibitory pharmacophore

Dewa, Amila Agampodi, Elbanna, Ahmed H., Khalil, Zeinab G. and Capon, Robert J. (2022). Neochrysosporazines: precursor-directed biosynthesis defines a marine-derived fungal natural product p-glycoprotein inhibitory pharmacophore. Journal of Medicinal Chemistry, 65 (3) acs.jmedchem.1c01989, 2610-2622. doi: 10.1021/acs.jmedchem.1c01989

Physical mixture of a cyclic lipopeptide vaccine induced high titres of opsonic IgG antibodies against group A streptococcus

Madge, Harrison Y. R., Huang, Wenbin, Gilmartin, Lachlan, Rigau-Planella, Berta, Hussein, Waleed M., Khalil, Zeinab G., Koirala, Prashamsa, Santiago, Viviene S., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2022). Physical mixture of a cyclic lipopeptide vaccine induced high titres of opsonic IgG antibodies against group A streptococcus. Biomaterials Science, 10 (1), 281-293. doi: 10.1039/d1bm01333e

Oxandrastins: antibacterial meroterpenes from an Australian mud dauber wasp nest-associated fungus, Penicillium sp. CMB-MD14

Elbanna, Ahmed H., Khalil, Zeinab G. and Capon, Robert J. (2021). Oxandrastins: antibacterial meroterpenes from an Australian mud dauber wasp nest-associated fungus, Penicillium sp. CMB-MD14. Molecules, 26 (23) 7144, 7144. doi: 10.3390/molecules26237144

Bhimamycin J, a rare benzo[f]isoindole-dione alkaloid from the marine-derived actinomycete Streptomyces sp. MS180069

Song, Fuhang, Yang, Na, Khalil, Zeinab G., Salim, Angela A., Han, Jiahui, Bernhardt, Paul V., Lin, Rui, Xu, Xiuli and Capon, Robert J. (2021). Bhimamycin J, a rare benzo[f]isoindole-dione alkaloid from the marine-derived actinomycete Streptomyces sp. MS180069. Chemistry and Biodiversity, 18 (11) e2100674, e2100674. doi: 10.1002/cbdv.202100674

Polycyclic C-deoxyaminoglycoside-polyketides from an Australian Pasture Plant Derived Streptomyces sp.

Wu, Taizong, Salim, Angela A., Khalil, Zeinab G. and Capon, Robert J. (2021). Polycyclic C-deoxyaminoglycoside-polyketides from an Australian Pasture Plant Derived Streptomyces sp.. Organic Letters, 23 (21) acs.orglett.1c02954, 8224-8228. doi: 10.1021/acs.orglett.1c02954

Methods in microbial biodiscovery

Salim, Angela A., Khalil, Zeinab G., Elbanna, Ahmed H., Wu, Taizong and Capon, Robert J. (2021). Methods in microbial biodiscovery. Marine Drugs, 19 (9) 503. doi: 10.3390/md19090503

Precursor-directed biosynthesis mediated amplification of minor aza phenylpropanoid piperazines in an Australian marine fish-gut-derived fungus, Chrysosporium sp. CMB-F214

Elbanna, Ahmed H., Agampodi Dewa, Amila, Khalil, Zeinab G. and Capon, Robert J. (2021). Precursor-directed biosynthesis mediated amplification of minor aza phenylpropanoid piperazines in an Australian marine fish-gut-derived fungus, Chrysosporium sp. CMB-F214. Marine Drugs, 19 (9) 478. doi: 10.3390/md19090478

Poly(hydrophobic amino acid) conjugates for the delivery of multiepitope vaccine against Group A Streptococcus

Azuar, Armira, Shibu, Mohini A., Adilbish, Nomin, Marasini, Nirmal, Hung, Hong, Yang, Jieru, Luo, Yacheng, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Poly(hydrophobic amino acid) conjugates for the delivery of multiepitope vaccine against Group A Streptococcus. Bioconjugate Chemistry, 32 (11) acs.bioconjchem.1c00333, 2307-2317. doi: 10.1021/acs.bioconjchem.1c00333

Polyethylenimine quantity and molecular weight influence its adjuvanting properties in liposomal peptide vaccines

Dai, Charles C., Huang, Wenbin, Yang, Jieru, Hussein, Waleed M., Wang, Jingwen, Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2021). Polyethylenimine quantity and molecular weight influence its adjuvanting properties in liposomal peptide vaccines. Bioorganic and Medicinal Chemistry Letters, 40 127920, 1-7. doi: 10.1016/j.bmcl.2021.127920

Cell-penetrating peptides-based liposomal delivery system enhanced immunogenicity of peptide-based vaccine against group A streptococcus

Yang, Jieru, Firdaus, Farrhana, Azuar, Armira, Khalil, Zeinab G., Marasini, Nirmal, Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Cell-penetrating peptides-based liposomal delivery system enhanced immunogenicity of peptide-based vaccine against group A streptococcus. Vaccines, 9 (5) 499, 499. doi: 10.3390/vaccines9050499

N-amino-L-proline methyl ester from an Australian fish gut-derived fungus: challenging the distinction between natural product and artifact

Mohamed, Osama G., Khalil, Zeinab G. and Capon, Robert J. (2021). N-amino-L-proline methyl ester from an Australian fish gut-derived fungus: challenging the distinction between natural product and artifact. Marine Drugs, 19 (3) 151, 1-14. doi: 10.3390/md19030151

Immunogenicity assessment of cell wall carbohydrates of Group A Streptococcus via self-adjuvanted glyco-lipopeptides

Khatun, Farjana, Dai, Charles C., Rivera-Hernandez, Tania, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2021). Immunogenicity assessment of cell wall carbohydrates of Group A Streptococcus via self-adjuvanted glyco-lipopeptides. ACS Infectious Diseases, 7 (2) acsinfecdis.0c00722, 390-405. doi: 10.1021/acsinfecdis.0c00722

Neobulgarones revisited: anti and syn bianthrones from an Australian mud dauber wasp nest-associated fungus, Penicillium sp. CMB-MD22

Elbanna, Ahmed H., Khalil, Zeinab G., Bernhardt, Paul V. and Capon, Robert J. (2021). Neobulgarones revisited: anti and syn bianthrones from an Australian mud dauber wasp nest-associated fungus, Penicillium sp. CMB-MD22. Journal of Natural Products, 84 (3) acs.jnatprod.0c01035, 762-770. doi: 10.1021/acs.jnatprod.0c01035

Poly(hydrophobic amino acid)-based self-adjuvanting nanoparticles for Group A Streptococcus vaccine delivery

Azuar, Armira, Li, Zhuoqing, Shibu, Mohini A., Zhao, Lili, Luo, Yacheng, Shalash, Ahmed O., Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Poly(hydrophobic amino acid)-based self-adjuvanting nanoparticles for Group A Streptococcus vaccine delivery. Journal of Medicinal Chemistry, 64 (5) acs.jmedchem.0c01660, 2648-2658. doi: 10.1021/acs.jmedchem.0c01660

A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: lipidation and polyelectrolyte complexes

Zhao, Lili, Yang, Jieru, Nahar, Ummey Jannatun, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2020). A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: lipidation and polyelectrolyte complexes. Bioorganic and Medicinal Chemistry, 28 (24) 115823, 115823. doi: 10.1016/j.bmc.2020.115823

Lincolnenins A–D: isomeric bactericidal bianthracenes from Streptomyces lincolnensis

Mohamed, Osama G., Khalil, Zeinab G., Salim, Angela A., Cui, Hui, Blumenthal, Antje and Capon, Robert J. (2020). Lincolnenins A–D: isomeric bactericidal bianthracenes from Streptomyces lincolnensis. The Journal of Organic Chemistry, 86 (16) acs.joc.0c02492, 11011-11018. doi: 10.1021/acs.joc.0c02492

Polyethylenimine: an intranasal adjuvant for liposomal peptide-based subunit vaccine against Group A Streptococcus

Dai, Charles C., Yang, Jieru, Hussein, Waleed M., Zhao, Lili, Wang, Xiumin, Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2020). Polyethylenimine: an intranasal adjuvant for liposomal peptide-based subunit vaccine against Group A Streptococcus. ACS Infectious Diseases, 6 (9) acsinfecdis.0c00452, 2502-2512. doi: 10.1021/acsinfecdis.0c00452

Exploring natural product artifacts: the polyketide enterocin warms to a ballet of isomers

Salim, Angela A., Samarasekera, Kaumadi, Khalil, Zeinab G. and Capon, Robert J. (2020). Exploring natural product artifacts: the polyketide enterocin warms to a ballet of isomers. Organic Letters, 22 (12) acs.orglett.0c01629, 4828-4832. doi: 10.1021/acs.orglett.0c01629

Levoglucosenone and its Pseudoenantiomer iso-Levoglucosenone as scaffolds for drug discovery and development

Liu, Xin, Carr, Paul, Gardiner, Michael G., Banwell, Martin G., Elbanna, Ahmed H., Khalil, Zeinab G. and Capon, Robert J. (2020). Levoglucosenone and its Pseudoenantiomer iso-Levoglucosenone as scaffolds for drug discovery and development. ACS Omega, 5 (23) acsomega.0c01331, 13926-13939. doi: 10.1021/acsomega.0c01331

Opsonic activity of conservative versus variable regions of the Group A Streptococcus M protein

Dai, Chuankai, Khalil, Zeinab G., Hussein, Waleed M., Yang, Jieru, Wang, Xiumin, Zhao, Lili, Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2020). Opsonic activity of conservative versus variable regions of the Group A Streptococcus M protein. Vaccines, 8 (2) 210, 210. doi: 10.3390/vaccines8020210

Structure–activity analysis of cyclic multicomponent lipopeptide self-adjuvanting vaccine candidates presenting Group A Streptococcus antigens

Madge, Harrison Y. R., Sharma, Hansa, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert John, Toth, Istvan and Stephenson, Rachel (2020). Structure–activity analysis of cyclic multicomponent lipopeptide self-adjuvanting vaccine candidates presenting Group A Streptococcus antigens. Journal of Medicinal Chemistry, 63 (10) acs.jmedchem.0c00203, 5387-5397. doi: 10.1021/acs.jmedchem.0c00203

Genomic and metabolomic analysis of Antarctic bacteria revealed culture and elicitation conditions for the production of antimicrobial compounds

Núñez-Montero, Kattia, Quezada-Solís, Damián, Khalil, Zeinab G., Capon, Robert J., Andreote, Fernando D. and Barrientos, Leticia (2020). Genomic and metabolomic analysis of Antarctic bacteria revealed culture and elicitation conditions for the production of antimicrobial compounds. Biomolecules, 10 (5) 673, 673. doi: 10.3390/biom10050673

Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus

Zhao, Lili, Jin, Wanli, Cruz, Jazmina Gonzalez, Marasini, Nirmal, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2020). Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus. Nanomaterials, 10 (5) 823, 823. doi: 10.3390/nano10050823

Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines

Skwarczynski, Mariusz, Zhao, Guangzu, Boer, Jennifer C., Ozberk, Victoria, Azuar, Armira, Gonzalez Cruz, Jazmina, Kumar Giddam, Ashwini, Khalil, Zeinab G., Pandey, Manisha, Shibu, Mohini A., Hussein, Waleed M., Nevagi, Reshma J., Batzloff, Michael R., Wells, James W., Capon, Robert J., Plebanski, Magdalena, Good, Michael F. and Toth, Istvan (2020). Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines. Science Advances, 6 (5) eaax2285, eaax2285. doi: 10.1126/sciadv.aax2285

Chrysosporazines F–M: P-glycoprotein inhibitory phenylpropanoid piperazines from an Australian marine fish derived fungus, Chrysosporium sp. CMB-F294

Mohamed, Osama G., Salim, Angela A., Khalil, Zeinab G., Elbanna, Ahmed H., Bernhardt, Paul V. and Capon, Robert J. (2020). Chrysosporazines F–M: P-glycoprotein inhibitory phenylpropanoid piperazines from an Australian marine fish derived fungus, Chrysosporium sp. CMB-F294. Journal of Natural Products, 83 (2) acs.jnatprod.9b01181, 497-504. doi: 10.1021/acs.jnatprod.9b01181

Polyacrylate–peptide antigen conjugate as a single-dose oral vaccine against Group A Streptococcus

Faruck, Mohammad Omer, Zhao, Lili, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Skwarczynski, Mariusz and Toth, Istvan (2020). Polyacrylate–peptide antigen conjugate as a single-dose oral vaccine against Group A Streptococcus. Vaccines, 8 (1) 23, 1-10. doi: 10.3390/vaccines8010023

Trivirensols: selectively bacteriostatic sesquiterpene trimers from the Australian termite nest-derived fungus Trichoderma virens CMB-TN16

Jiao, Wei-Hua, Salim, Angela A., Khalil, Zeinab G., Dewapriya, Pradeep, Lin, Hou-Wen, Butler, Mark S. and Capon, Robert J. (2019). Trivirensols: selectively bacteriostatic sesquiterpene trimers from the Australian termite nest-derived fungus Trichoderma virens CMB-TN16. Journal of Natural Products, 82 (11), 3165-3175. doi: 10.1021/acs.jnatprod.9b00760

Talarophenol sulfate and talarophilones from the Australian mud dauber wasp-associated fungus, Talaromyces sp. CMB-W045

Kalansuriya, Pabasara, Khalil, Zeinab G., Salim, Angela A. and Capon, Robert J. (2019). Talarophenol sulfate and talarophilones from the Australian mud dauber wasp-associated fungus, Talaromyces sp. CMB-W045. Tetrahedron Letters, 60 (43) 151157, 151157. doi: 10.1016/j.tetlet.2019.151157

Chrysosporazines A–E: P-glycoprotein inhibitory piperazines from an Australian marine fish gastrointestinal tract-derived fungus, Chrysosporium sp. CMB-F214

Elbanna, Ahmed H., Khalil, Zeinab G., Bernhardt, Paul V. and Capon, Robert J. (2019). Chrysosporazines A–E: P-glycoprotein inhibitory piperazines from an Australian marine fish gastrointestinal tract-derived fungus, Chrysosporium sp. CMB-F214. Organic Letters, 21 (19) acs.orglett.9b03094, 8097-8100. doi: 10.1021/acs.orglett.9b03094

Scopularides revisited: molecular networking guided exploration of lipodepsipeptides in Australian marine fish gastrointestinal tract-derived fungi

Elbanna, Ahmed H., Khalil, Zeinab G., Bernhardt, Paul V. and Capon, Robert J. (2019). Scopularides revisited: molecular networking guided exploration of lipodepsipeptides in Australian marine fish gastrointestinal tract-derived fungi. Marine Drugs, 17 (8) 475, 475. doi: 10.3390/md17080475

Cholic acid-based delivery system for vaccine candidates against Group A Streptococcus

Azuar, Armira, Zhao, Lili, Hei, Tsui Ting, Nevagi, Reshma J., Bartlett, Stacey, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Skwarczynski, Mariusz (2019). Cholic acid-based delivery system for vaccine candidates against Group A Streptococcus. ACS Medicinal Chemistry Letters, 10 (9) acsmedchemlett.9b00239, 1253-1259. doi: 10.1021/acsmedchemlett.9b00239

Self-assembly of trimethyl chitosan and poly(anionic amino acid)-peptide antigen conjugate to produce a potent self-adjuvanting nanovaccine delivery system

Nevagi, Reshma J., Dai, Wei, Khalil, Zeinab G., Hussein, Waleed M., Capon, Robert J., Skwarczynski, Mariusz and Toth, Istvan (2019). Self-assembly of trimethyl chitosan and poly(anionic amino acid)-peptide antigen conjugate to produce a potent self-adjuvanting nanovaccine delivery system. Bioorganic and Medicinal Chemistry, 27 (14), 3082-3088. doi: 10.1016/j.bmc.2019.05.033

Structure-activity relationship of group A streptococcus lipopeptide vaccine candidates in trimethyl chitosan-based self-adjuvanting delivery system

Nevagi, Reshma J., Dai, Wei, Khalil, Zeinab G., Hussein, Waleed M., Capon, Robert J., Skwarczynski, Mariusz and Toth, Istvan (2019). Structure-activity relationship of group A streptococcus lipopeptide vaccine candidates in trimethyl chitosan-based self-adjuvanting delivery system. European Journal of Medicinal Chemistry, 179, 100-108. doi: 10.1016/j.ejmech.2019.06.047

Solvolysis artifacts: leucettazoles as cryptic macrocyclic alkaloid dimers from a Southern Australian marine sponge, Leucetta sp.

Prasad, Pritesh, Salim, Angela A., Khushi, Shamsunnahar, Khalil, Zeinab G., Quezada, Michelle and Capon, Robert J. (2019). Solvolysis artifacts: leucettazoles as cryptic macrocyclic alkaloid dimers from a Southern Australian marine sponge, Leucetta sp.. Marine Drugs, 17 (2) md17020106, 106. doi: 10.3390/md17020106

Bromocatechol conjugates from a Chinese marine red alga, Symphyocladia latiuscula

Xu, Xiuli, Yang, Haijin, Khalil, Zeinab G., Yin, Liyuan, Xiao, Xue, Salim, Angela A., Song, Fuhang and Capon, Robert J. (2019). Bromocatechol conjugates from a Chinese marine red alga, Symphyocladia latiuscula. Phytochemistry, 158, 20-25. doi: 10.1016/j.phytochem.2018.10.026

Structure-activity relationships of wollamide cyclic hexapeptides with activity against drug-resistant and intracellular

Khalil, Zeinab G., Hill, Timothy A., De Leon Rodriguez, Luis M., Lohman, Rink-Jan, Hoang, Huy N., Reiling, Norbert, Hillemann, Doris, Brimble, Margaret A., Fairlie, David, Blumenthal, Antje and Capon, Robert J. (2019). Structure-activity relationships of wollamide cyclic hexapeptides with activity against drug-resistant and intracellular. Antimicrobial Agents and Chemotherapy, 63 (3) e01773-18. doi: 10.1128/AAC.01773-18

Divirensols: Sesquiterpene Dimers from the Australian Termite Nest-Derived Fungus Trichoderma virens CMB-TN16

Jiao, Wei-Hua, Dewapriya, Pradeep, Mohamed, Osama, Khalil, Zeinab G., Salim, Angela A., Lin, Hou-Wen and Capon, Robert J. (2018). Divirensols: Sesquiterpene Dimers from the Australian Termite Nest-Derived Fungus Trichoderma virens CMB-TN16. Journal of Natural Products, 82 (1) acs.jnatprod.8b00746, 87-95. doi: 10.1021/acs.jnatprod.8b00746

Talaropeptides A-D: Structure and Biosynthesis of Extensively N-methylated Linear Peptides From an Australian Marine Tunicate-Derived Talaromyces sp

Dewapriya, Pradeep, Khalil, Zeinab G., Prasad, Pritesh, Salim, Angela A., Cruz-Morales, Pablo, Marcellin, Esteban and Capon, Robert J. (2018). Talaropeptides A-D: Structure and Biosynthesis of Extensively N-methylated Linear Peptides From an Australian Marine Tunicate-Derived Talaromyces sp. Frontiers in Chemistry, 6 394, 394. doi: 10.3389/fchem.2018.00394

Inter-Kingdom beach warfare: Microbial chemical communication activates natural chemical defences

Khalil, Zeinab G., Cruz-Morales, Pablo, Licona-Cassani, Cuauhtemoc, Marcellin, Esteban and Capon, Robert J. (2018). Inter-Kingdom beach warfare: Microbial chemical communication activates natural chemical defences. The ISME journal, 13 (1), 147-158. doi: 10.1038/s41396-018-0265-z

Trichodermides A-E: New peptaibols isolated from the Australian termite nest-derived fungus trichoderma virens CMB-TN16

Jiao, Wei-Hua, Khalil, Zeinab, Dewapriya, Pradeep, Salim, Angela A, Lin, Hou-Wen and Capon, Robert J (2018). Trichodermides A-E: New peptaibols isolated from the Australian termite nest-derived fungus trichoderma virens CMB-TN16. Journal of Natural Products, 81 (4), 976-984. doi: 10.1021/acs.jnatprod.7b01072

Prolinimines: N-Amino-l-Pro-methyl Ester (Hydrazine) Schiff Bases from a Fish Gastrointestinal Tract-Derived Fungus, Trichoderma sp. CMB-F563

Mohamed, Osama G, Khalil, Zeinab G and Capon, Robert J (2018). Prolinimines: N-Amino-l-Pro-methyl Ester (Hydrazine) Schiff Bases from a Fish Gastrointestinal Tract-Derived Fungus, Trichoderma sp. CMB-F563. Organic letters, 20 (2), 377-380. doi: 10.1021/acs.orglett.7b03666

Polyglutamic acid-trimethyl chitosan-based intranasal peptide nano-vaccine induces potent immune responses against group A streptococcus

Nevagi, Reshma J., Khalil, Zeinab G., Hussein, Waleed M., Powell, Jessica, Batzloff, Michael R., Capon, Robert J., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2018). Polyglutamic acid-trimethyl chitosan-based intranasal peptide nano-vaccine induces potent immune responses against group A streptococcus. Acta Biomaterialia, 80, 278-287. doi: 10.1016/j.actbio.2018.09.037

Chemical Diversity from a Chinese Marine Red Alga, Symphyocladia latiuscula

Xu, Xiuli, Yang, Haijin, Khalil, Zeinab G, Yin, Liyuan, Xiao, Xue, Neupane, Pratik, Bernhardt, Paul V, Salim, Angela A, Song, Fuhang and Capon, Robert J (2017). Chemical Diversity from a Chinese Marine Red Alga, Symphyocladia latiuscula. Marine drugs, 15 (12) 374, 1-10. doi: 10.3390/md15120374

Amycolatopsins A-C: antimycobacterial glycosylated polyketide macrolides from the Australian soil Amycolatopsis sp. MST-108494

Khalil, Zeinab G., Salim, Angela A., Vuong, Daniel, Crombie, Andrew, Lacey, Ernest, Blumenthal, Antje and Capon, Robert J. (2017). Amycolatopsins A-C: antimycobacterial glycosylated polyketide macrolides from the Australian soil Amycolatopsis sp. MST-108494. The Journal of Antibiotics, 70 (12), 1097-1103. doi: 10.1038/ja.2017.119

Cytochalasins from an Australian Marine Sediment-Derived Phomopsis sp. (CMB-M0042F): Acid-Mediated Intramolecular Cycloadditions Enhance Chemical Diversity

Shang, Zhuo, Raju, Ritesh, Salim, Angela A., Khalil, Zeinab G. and Capon, Robert J. (2017). Cytochalasins from an Australian Marine Sediment-Derived Phomopsis sp. (CMB-M0042F): Acid-Mediated Intramolecular Cycloadditions Enhance Chemical Diversity. Journal of Organic Chemistry, 82 (18), 9704-9709. doi: 10.1021/acs.joc.7b01793

Double adjuvanting strategy for peptide-based vaccines: trimethyl chitosan nanoparticles for lipopeptide delivery

Marasini, Nirmal, Giddam, Ashwini K., Khalil, Zeinab G., Hussein, Waleed M., Capon, Robert J., Batzloff, Michael R., Good, Michael F., Toth, Istvan and Skwarczynski, Mariusz (2016). Double adjuvanting strategy for peptide-based vaccines: trimethyl chitosan nanoparticles for lipopeptide delivery. Nanomedicine, 11 (24), 3223-3235. doi: 10.2217/nnm-2016-0291

Lipid core peptide/poly(lactic-co-glycolic acid) as a highly potent intranasal vaccine delivery system against Group A streptococcus

Marasini, Nirmal, Khalil, Zeinab G., Giddam, Ashwini K., Abdul Ghaffar, Khairunnisa, Hussein, Waleed M., Capon, Robert J., Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2016). Lipid core peptide/poly(lactic-co-glycolic acid) as a highly potent intranasal vaccine delivery system against Group A streptococcus. International Journal of Pharmaceutics, 513 (1-2), 410-420. doi: 10.1016/j.ijpharm.2016.09.057

Roseopurpurins: chemical diversity enhanced by convergent biosynthesis and forward and reverse Michael additions

Shang, Zhuo, Khalil, Zeinab, Li, Li, Salim, Angela A., Quezada, Michelle, Kalansuriya, Pabasara and Capon, Robert J. (2016). Roseopurpurins: chemical diversity enhanced by convergent biosynthesis and forward and reverse Michael additions. Organic Letters, 18 (17), 4340-4343. doi: 10.1021/acs.orglett.6b02099

Linear and branched polyacrylates as a delivery platform for peptide-based vaccines

Chandrudu, Saranya, Bartlett, Stacey, Khalil, Zeinab G., Jia, Zhongfan, Hussein, Waleed M., Capon, Robert J., Batzloff, Michael R., Good, Michael F., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2016). Linear and branched polyacrylates as a delivery platform for peptide-based vaccines. Therapeutic Delivery, 7 (9), 601-609. doi: 10.4155/tde-2016-0037

Fungal biotransformation of tetracycline antibiotics

Shang, Zhuo, Salim, Angela A., Khalil, Zeinab, Bernhardt, Paul V. and Capon, Robert J. (2016). Fungal biotransformation of tetracycline antibiotics. Journal of Organic Chemistry, 81 (15), 6186-6194. doi: 10.1021/acs.joc.6b01272

C3 and 2D C3 Marfey’s methods for amino acid analysis in natural products

Vijayasarathy, Soumini, Prasad, Pritesh, Fremlin, Leith J., Ratnayake, Ranjala, Salim, Angela A., Khalil, Zeinab and Capon, Robert J. (2016). C3 and 2D C3 Marfey’s methods for amino acid analysis in natural products. Journal of Natural Products, 79 (2), 421-427. doi: 10.1021/acs.jnatprod.5b01125

Viridicatumtoxins: Expanding on a Rare Tetracycline Antibiotic Scaffold

Shang, Zhuo, Salim, Angela A., Khalil, Zeinab, Quezada, Michelle, Bernhardt, Paul V. and Capon, Robert J. (2015). Viridicatumtoxins: Expanding on a Rare Tetracycline Antibiotic Scaffold. Journal of Organic Chemistry, 80 (24), 12501-12508. doi: 10.1021/acs.joc.5b02367

New PKS-NRPS tetramic acids and pyridinone from an Australian marine-derived fungus, Chaunopycnis sp.

Shang, Zhuo, Li, Li, Esposito, Breno P., Salim, Angela A., Khalil, Zeinab G., Quezada, Michelle, Bernhardt, Paul V. and Capon, Robert J. (2015). New PKS-NRPS tetramic acids and pyridinone from an Australian marine-derived fungus, Chaunopycnis sp.. Organic and Biomolecular Chemistry, 13 (28), 7795-7802. doi: 10.1039/c5ob01058f

Aranciamycins I and J, Antimycobacterial Anthracyclines from an Australian marine-derived Streptomyces sp.

Khalil, Zeinab G., Raju, Ritesh, Piggott, Andrew M., Salim, Angela A., Blumenthal, Antje and Capon, Robert J. (2015). Aranciamycins I and J, Antimycobacterial Anthracyclines from an Australian marine-derived Streptomyces sp.. Journal of Natural Products, 78 (4), 949-952. doi: 10.1021/acs.jnatprod.5b00095

Atropselective syntheses of (-) and (+) rugulotrosin A utilizing point-to-axial chirality transfer

Qin, Tian, Skraba-Joiner, Sarah L., Khalil, Zeinab G., Johnson, Richard P., Capon, Robert J. and Porco, John A. Jr (2015). Atropselective syntheses of (-) and (+) rugulotrosin A utilizing point-to-axial chirality transfer. Nature Chemistry, 7 (3), 234-240. doi: 10.1038/nchem.2173

Levofloxacin and indolicidin for combination antimicrobial therapy

Ghaffar, Khairunnisa Abdul, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Skwarczynski, Mariusz and Toth, Istvan (2015). Levofloxacin and indolicidin for combination antimicrobial therapy. Current Drug Delivery, 12 (1), 108-114. doi: 10.2174/1567201811666140910094050

Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains

Azmi, Fazren, Elliott, Alysha G., Khalil, Zeinab G., Hussein, Waleed M., Kavanagh, Angela, Huang, Johnny X., Quezada, Michelle, Blaskovich, Mark A. T., Capon, Robert J., Cooper, Matthew A., Skwarczynski, Mariusz and Toth, Istvan (2015). Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains. Nanomedicine, 10 (22), 3359-3371. doi: 10.2217/nnm.15.137

Isolation and synthesis of N-acyladenine and adenosine alkaloids from a southern Australian marine sponge, Phoriospongia sp.

Farrugia, Michelle, Trotter, Nicholas, Vijayasarathy, Soumini, Salim, Angele A., Khalil, Zeinab G., Lacey, Ernest and Capon, Robert J. (2014). Isolation and synthesis of N-acyladenine and adenosine alkaloids from a southern Australian marine sponge, Phoriospongia sp.. Tetrahedron Letters, 55 (43), 5902-5904. doi: 10.1016/j.tetlet.2014.08.116

Wollamides: antimycobacterial cyclic hexapeptides from an Australian soil Streptomyces

Khalil, Zeinab G., Salim, Angela A., Lacey, Ernest, Blumenthal, Antje and Capon, Robert J. (2014). Wollamides: antimycobacterial cyclic hexapeptides from an Australian soil Streptomyces. Organic Letters, 16 (19), 5120-5123. doi: 10.1021/ol502472c

Shornephine A: structure, chemical stability, and P-Glycoprotein inhibitory properties of a rare Diketomorpholine from an Australian marine-derived Aspergillus sp.

Khalil, Zeinab G., Huang, Xiao-cong, Raju, Ritesh, Piggott, Andrew M. and Capon, Robert J. (2014). Shornephine A: structure, chemical stability, and P-Glycoprotein inhibitory properties of a rare Diketomorpholine from an Australian marine-derived Aspergillus sp.. Journal of Organic Chemistry, 79 (18), 8700-8705. doi: 10.1021/jo501501z

Heronapyrrole D: a case of co-inspiration of natural product biosynthesis, total synthesis and biodiscovery

Schmidt, Jens, Khalil, Zeinab, Capon, Robert J. and Stark, Christian B. W. (2014). Heronapyrrole D: a case of co-inspiration of natural product biosynthesis, total synthesis and biodiscovery. Beilstein Journal of Organic Chemistry, 10 (1), 1228-1232. doi: 10.3762/bjoc.10.121

Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244)

Raju, Ritesh, Khalil, Zeinab G., Piggott, Andrew M., Blumenthal, Antje, Gardiner, Donald L., Skinner-Adams, Tina S. and Capon, Robert J. (2014). Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244). Organic Letters, 16 (6), 1716-1719. doi: 10.1021/ol5003913

Callyspongisines A-D: Bromopyrrole alkaloids from an Australian marine sponge, Callyspongia sp.

Plisson,Fabien, Prasad, Pritesh, Xiao, Xue, Piggott, Andrew M., Huang, Xiao-cong, Khalil, Zeinab and Capon, Robert J. (2014). Callyspongisines A-D: Bromopyrrole alkaloids from an Australian marine sponge, Callyspongia sp.. Organic and Biomolecular Chemistry, 12 (10), 1579-1584. doi: 10.1039/c4ob00091a

Lipopolysaccharide (LPS) stimulation of fungal secondary metabolism

Khalil, Zeinab G., Kalansuriya, Pabasara and Capon, Robert J. (2014). Lipopolysaccharide (LPS) stimulation of fungal secondary metabolism. Mycology, 5 (3), 168-178. doi: 10.1080/21501203.2014.930530

Structural and stereochemical investigations into bromotyrosine-derived metabolites from southern Australian marine sponges, Pseudoceratina spp.

Salim, Angela A., Khalil, Zeinab G. and Capon, Robert J. (2012). Structural and stereochemical investigations into bromotyrosine-derived metabolites from southern Australian marine sponges, Pseudoceratina spp.. Tetrahedron, 68 (47), 9802-9807. doi: 10.1016/j.tet.2012.09.008

A search for kinase inhibitors and antibacterial agents: bromopyrrolo-2-aminoimidazoles from a deep-water Great Australian Bight sponge, Axinella sp.

Zhang, Hua, Khalil, Zeinab, Conte, Melissa M., Plisson, Fabien and Capon, Robert J. (2012). A search for kinase inhibitors and antibacterial agents: bromopyrrolo-2-aminoimidazoles from a deep-water Great Australian Bight sponge, Axinella sp.. Tetrahedron Letters, 53 (29), 3784-3787. doi: 10.1016/j.tetlet.2012.05.051

Kinase inhibitor scaffolds against neurodegenerative diseases from a southern Australian Ascidian, Didemnum sp.

Plisson, Fabien, Conte, Melissa, Khalil, Zeinab, Huang, Xiao-Cong, Piggott, Andrew M. and Capon, Robert J. (2012). Kinase inhibitor scaffolds against neurodegenerative diseases from a southern Australian Ascidian, Didemnum sp.. ChemMedChem, 7 (6), 983-990. doi: 10.1002/cmdc.201200169

Lamellarins as inhibitors of P-glycoprotein-mediated multidrug resistance in a human colon cancer cell line

Plisson, Fabien, Huang, Xiao-Cong, Zhang, Hua, Khalil, Zeinab and Capon, Robert J. (2012). Lamellarins as inhibitors of P-glycoprotein-mediated multidrug resistance in a human colon cancer cell line. Chemistry - An Asian Journal, 7 (7), 1616-1623. doi: 10.1002/asia.201101049

New dictyodendrins as BACE inhibitors from a southern Australian marine sponge, Ianthella sp.

Zhang, Hua, Conte, Melissa M., Khalil, Zeinab, Huang, Xiao-Cong and Capon, Robert J. (2012). New dictyodendrins as BACE inhibitors from a southern Australian marine sponge, Ianthella sp.. Rsc Advances, 2 (10), 4209-4214. doi: 10.1039/c2ra20322g

A search for BACE inhibitors reveals new biosynthetically related pyrrolidones, furanones and pyrroles from a southern Australian marine sponge, Ianthella sp.

Zhang, Hua, Conte, Melissa M., Huang, Xiao-Cong, Khalil, Zeinab and Capon, Robert J. (2012). A search for BACE inhibitors reveals new biosynthetically related pyrrolidones, furanones and pyrroles from a southern Australian marine sponge, Ianthella sp.. Organic and Biomolecular Chemistry, 10 (13), 2656-2663. doi: 10.1039/c2ob06747a

Heronamycin A: A new benzothiazine ansamycin from an Australian marine-derived Streptomyces sp.

Raju, Ritesh, Piggott, Andrew M., Khalil, Zeinab, Bernhardt, Paul V. and Capon, Robert J. (2012). Heronamycin A: A new benzothiazine ansamycin from an Australian marine-derived Streptomyces sp.. Tetrahedron Letters, 53 (9), 1063-1065. doi: 10.1016/j.tetlet.2011.12.064

Spiralisones A-D: acylphloroglucinol hemiketals from an Australian marine brown alga, Zonaria spiralis

Zhang, Hua, Xiao, Xue, Conte, Melissa M., Khalil, Zeinab and Capon, Robert J. (2012). Spiralisones A-D: acylphloroglucinol hemiketals from an Australian marine brown alga, Zonaria spiralis. Organic and Biomolecular Chemistry, 10 (48), 9671-9676. doi: 10.1039/c2ob26988k

Ikirydinium A: A new indole alkaloid from the seeds of Hunteria umbellata (K. Schum)

Ajala, Olusegun S., Piggott, Andrew M., Plisson, Fabien, Zeinab, Zeinab, Huang, Xiao-cong, Adesegun, Sunday A., Coker, Herbert A. B. and Capon, Robert J. (2011). Ikirydinium A: A new indole alkaloid from the seeds of Hunteria umbellata (K. Schum). Tetrahedron Letters, 52 (52), 7125-7127. doi: 10.1016/j.tetlet.2011.10.106

Fascioquinols A-F: Bioactive meroterpenes from a deep-water southern Australian marine sponge, Fasciospongia sp

Zhang, Hua, Khalil, Zeinab G. and Capon, Robert J. (2011). Fascioquinols A-F: Bioactive meroterpenes from a deep-water southern Australian marine sponge, Fasciospongia sp. Tetrahedron, 67 (14), 2591-2595. doi: 10.1016/j.tet.2011.02.015

Reveromycins revealed: New polyketide spiroketals from Australian marine-derived and terrestrial Streptomyces spp. A case of natural products vs artifacts

Fremlin, Leith, Farrugia, Michelle, Piggott, Andrew M., Khalil, Zeinab, Lacey, Ernest and Capon, Robert J. (2011). Reveromycins revealed: New polyketide spiroketals from Australian marine-derived and terrestrial Streptomyces spp. A case of natural products vs artifacts. Organic & Biomolecular Chemistry, 9 (4), 1201-1211. doi: 10.1039/c0ob00654h

Heronapyrroles A-C: Farnesylated 2-nitropyrroles from an Australian marine-derived Streptomyces sp.

Raju, Ritesh, Piggott, Andrew M., Barrientos Diaz, Leticia X., Khalil, Zeinab and Capon, Robert J. (2010). Heronapyrroles A-C: Farnesylated 2-nitropyrroles from an Australian marine-derived Streptomyces sp.. Organic Letters, 12 (22), 5158-5161. doi: 10.1021/ol102162d

Heterofibrins: Inhibitors of lipid droplet formation from a deep-water southern Australian marine sponge, Spongia (Heterofibria) sp.

Salim, Angela A., Rae, James, Fontaine, Frank, Conte, Melissa M., Khalil, Zeinab, Martin, Sally, Parton, Robert G. and Capon, Robert J. (2010). Heterofibrins: Inhibitors of lipid droplet formation from a deep-water southern Australian marine sponge, Spongia (Heterofibria) sp.. Organic and Biomolecular Chemistry, 8 (14), 3188-3194. doi: 10.1039/c003840g

9-(5‘-Deoxy-5’-thio-β-d-xylofuranosyl)adenine disulfide from the Southern Australian marine sponge trachycladus laevispirulifer: The first natural occurrence of a nucleoside disulfide

Peng, Chongsheng, Gunaherath, G. M. Kamal B., Piggott, Andrew M., Khalil, Zeinab, Conte, Melissa and Capon, Robert J. (2010). 9-(5‘-Deoxy-5’-thio-β-d-xylofuranosyl)adenine disulfide from the Southern Australian marine sponge trachycladus laevispirulifer: The first natural occurrence of a nucleoside disulfide. Australian Journal of Chemistry, 63 (6), 873-876. doi: 10.1071/CH09645

Development of polymer-based nanoparticulate intranasal lipopeptide vaccine constructs against group A streptococcus

Nevagi, Reshma Jayprakash, Dai, Wei, Khalil, Zeinab, Hussein, Waleed, Capon, Robert, Skwarczynski, Mariusz and Toth, Istvan (2019). Development of polymer-based nanoparticulate intranasal lipopeptide vaccine constructs against group A streptococcus. National Meeting of the American Chemical Society (ACS), Orlando, FL, United States, 31 March - 4 April, 2019. Washington, DC, United States: American Chemical Society.

Talaropeptides A–D: Structure and biosynthesis of extensively N-methylated linear peptides from an Australian marine tunicate-derived Talaromyces sp.

Dewapriya, Pradeep, Khalil, Zeinab G., Prasad, Pritesh, Salim, Angela A., Morales, Pablo C., Marcellin, Esteban and Capon, Robert J. (2018). Talaropeptides A–D: Structure and biosynthesis of extensively N-methylated linear peptides from an Australian marine tunicate-derived Talaromyces sp.. American Society of Pharmacognosy Annual Meeting ASP 2018, Lexington, KY United States, 21-25 July 2018.

2D C3 Marfey’s method for amino acid analysis and structure elucidation in peptidic natural products

Dewapriya, Pradeep, Prasad, Pritesh, Khalil, Zeinab G. and Capon, Robert J. (2017). 2D C3 Marfey’s method for amino acid analysis and structure elucidation in peptidic natural products. Queensland Annual Chemistry Symposium, Brisbane, Australia, 27 November 2017.

Viridicatumtoxins: Exploring structural diversity and antibiotic properties

Shang, Z., Salim, A. A., Khalil, Z. G., Quezada, M., Bernhardt, P. V. and Capon, R. J. (2015). Viridicatumtoxins: Exploring structural diversity and antibiotic properties. Annual Meeting of the American-Society-of-Pharmacognosy, Copper Mountain, CO, United States, 25-29 July 2015. Stuttgart, Germany: Georg Thieme. doi: 10.1055/s-0035-1556338

Innovations in Microbial Biodiscovery, Targeting Silent Metabolism and New Chemical Diversity

Khalil, Zeinab (2013). Innovations in Microbial Biodiscovery, Targeting Silent Metabolism and New Chemical Diversity. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/uql.2017.734