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facilitating precision medicine and may provide a wealth of information for future studies…
Research officer, Medical Genomics
QIMR Berghofer Medical Research Institute
My research addressed the challenges related to key genomic components in tumour-immune editing variation in cancers with poor survival and predicting the responses to cancer immunotherapies. Characterizing genomic determinants in underlying response and resistance to cancer immunotherapy. Through w …
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universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem… therapeutics to promote rapid and more effective recovery following an acute cardiovascular event… Regenerative medicine: reprogramming the injured heart… Cardiovascular Development and Disease: Discovery science to translational applications… , and single cell RNA-sequencing to study how cells differentiate into cell types of the heart… : Postdoctoral Research Fellow, University of Washington, Institute for Stem Cell and Regenerative Medicine… science and clinical applications, we discuss how ZFN research can address some of the ethical and…
Career Summary: 2009: PhD, University of Michigan, USA with training in cardiac physiology, modelling myocardial ischemia in vivo and in vitro, and development of therapeutic approaches for myocardial ischemia; 2009–2015: Postdoctoral Research Fellow, University of Washington, Institute for Stem Cel …
Advancing stem cells toward clinical testing: Work by Dr Palpant on iPSC genome engineering and differentiation protocols led to him receiving the 2015 Young Investigator Award from the International Society for Heart Research. This work resulted in a licensed patent (US Patent 10,612,002; 2020) on …
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sequence in a human body to create astoundingly diverse forms and functions. This project integrates… cell types will contribute to early disease diagnosis, targeted drug discovery and precision medicine.… Expression specificity of disease-associated lncRNAs: toward personalized medicine… contributes to early disease diagnosis, targeted drug discovery and precision medicine… Biomedical Machine Learning… of Queensland. He is leading the Genomics and Machine Learning (GML) lab to study neuroinflammation… allows for the discovery and ranking of clinically relevant alternative medicines based on their…
Dr Quan Nguyen is a Group Leader at the Institute for Molecular Bioscience (IMB), The University of Queensland. He is leading the Genomics and Machine Learning (GML) lab to study neuroinflammation and cancer-immune cells at single-cell resolution and within spatial morphological tissue context. His …
Genomics research for the past decade has relied on data from bulk sequencing of dissociated tissues. The problem with this approach is it discards both intercellular variation among cancer cells and spatial information within a tumour. Dr Nguyen's Cancer Spatial Omics (CSO) program applied spatial …
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Patient care standards for primary mitochondrial disease in Australia: an Australian adaptation of the Mitochondrial Medicine Society recommendations… David is a Consultant Paediatrician, Metabolic Physician, Clinical Geneticist and clinician… biomedical and genetic testing fails to identify which subgroup of infants with galactosaemia are at…
David is a Consultant Paediatrician, Metabolic Physician, Clinical Geneticist and clinician researcher. His area of expertise is the diagnosis and management of children with rare diseases. David is involved in multiple ongoing research projects aimed at novel disease discovery, improved diagnostic …
David has close relationships with research colleagues both in Australia and internationally. He has multiple ongoing research projects investigating novel disease identification, the genetics of paediatric speech disorders and the development of new therapeutic possibilities for children and adults …
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University of Queensland. Clara’s research focuses on using genomic and transcriptomic analysis to… L1 transposons occupy 17% of the human genome and are widely exapted for the regulation of human…
Clara Jiang is a postdoctoral research fellow at the Institute for Molecular Bioscience, the University of Queensland. Clara’s research focuses on using genomic and transcriptomic analysis to investigate the genetic basis of cardiovascular and psychiatric disorders, with a particular focus on fema …
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Optimizing genomic medicine in epilepsy through a gene-customized approach to missense variant interpretation… increases, these approaches can be used to inform treatment strategies and personalised medicine.… Prof David Ascher is currently an NHMRC Investigator and Director of the Biotechnology Program… personalized medicine, their development and optimization has been largely through experimental exploration…
Prof David Ascher is currently an NHMRC Investigator and Director of the Biotechnology Program at the University of Queensland. He is also Head of Computational Biology and Clinical Informatics at the Baker Institute.
David’s research focus is in modelling biological data to gain insight into fun …
We have successfully translated our computational tools into the clinic and industry, including:
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