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Cancers expressing the multidrug transporter P-glycoprotein (P-gp) exhibit chemotherapy resistance… antimicrobial resistance, cancer chemotherapy resistance… Extracellular vesicle lipids in cancer immunoevasion… Understanding multidrug resistance in cancer: identification of the substrate and inhibitor binding sites in P-glycoprotein… evidence that altered cell homeostasis, ranging from inflammatory processes to cancer, cause alterations in… major mechanism in the resistance of cancer cells to chemotherapy. ABCB1 is a poly specific…
Megan O’Mara is a Professor and Group Leader at the Australian Institute for Bioengineering and Nanotechnology (AIBN), UQ. Her group uses multiscale modelling techniques to understand how changes in the biochemical environment of the cell membranes alters membrane properties and modulates the func …
My research uses computational techniques and simulations to understand how the chemistry of biological and bioinspired systems influence their physical properties. My goal is to understand how biomolecules self-assemble and self-regulate in living cells. My work allows the rational design of new ph …
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