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Therapeutic Opportunity in Cancers with Poor Survival… Complex neoantigen prediction in cancers… genome sequencing technologies in biomedical research. In particular large cancer research…
Research officer, Medical Genomics
QIMR Berghofer Medical Research Institute
My research addressed the challenges related to key genomic components in tumour-immune editing variation in cancers with poor survival and predicting the responses to cancer immunotherapies. Characterizing genomic determinants in underlying response and resistance to cancer immunotherapy. Through w …
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Spatial omics and multiplexed imaging to explore cancer biology… The molecular basis of breast cancer in young women… Nguyen group’s research is focused on understanding cancer complexity at tissue level by… and cancer-immune cells at single-cell resolution and within spatial morphological tissue context… ageing, cancer and an increasing number of identified pathological conditions. Here we show that…
Dr Quan Nguyen is a Group Leader at the Institute for Molecular Bioscience (IMB), The University of Queensland. He is leading the Genomics and Machine Learning (GML) lab to study neuroinflammation and cancer-immune cells at single-cell resolution and within spatial morphological tissue context. His …
Genomics research for the past decade has relied on data from bulk sequencing of dissociated tissues. The problem with this approach is it discards both intercellular variation among cancer cells and spatial information within a tumour. Dr Nguyen's Cancer Spatial Omics (CSO) program applied spatial …
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Widespread exaptation of L1 transposons for transcription factor binding in breast cancer… experiments to decipher the genetic aetiology of breast cancer, specifically the regulatory role of… genes, particularly in breast cancer, where we have previously shown abundant cancer-specific…
Clara Jiang is a postdoctoral research fellow at the Institute for Molecular Bioscience, the University of Queensland. Clara’s research focuses on using genomic and transcriptomic analysis to investigate the genetic basis of cardiovascular and psychiatric disorders, with a particular focus on fema …
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Cancer is caused by the hyperactivity of genes that are difficult to drug. Utilising the unique… Long noncoding RNAs and the genetics of cancer… Targeting liver cancer with mRNA therapies… infectious diseases and cancer. mRNA-based gene therapies have the potential to alleviate a myriad of… HERA Grant, a Cancer Australia Grant (2021), Mater Foundation seeding grant (2019), a UQ ECR grant… Breast cancer risk is strongly associated with an intergenic region on 11q13. We have previously…
Dr Seth Cheetham is an ARC Discovery Early Career Award Fellow and group leader at the Australian Institute for Bioengineering and Nanotechnology. He is also the Deputy Director of the BASE facility, Australia's leading mRNA manufacturing hub. He completed his PhD at the University of Cambridge, sup …
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Development of cancer surveillance guidelines in ataxia telangiectasia: A Delphi‐based consensus survey of international experts… vulnerability to cancer. Despite this increased cancer risk, there are no widely accepted guidelines for…
David is a Consultant Paediatrician, Metabolic Physician, Clinical Geneticist and clinician researcher. His area of expertise is the diagnosis and management of children with rare diseases. David is involved in multiple ongoing research projects aimed at novel disease discovery, improved diagnostic …
David has close relationships with research colleagues both in Australia and internationally. He has multiple ongoing research projects investigating novel disease identification, the genetics of paediatric speech disorders and the development of new therapeutic possibilities for children and adults …
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