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Our focus is on the identification and evaluation of molecular targets and biomarkers of cancer. As… Expression profiles and functional associations of endogenous androgen receptor and caveolin-1 in prostate cancer cell lines… Cellular targets for cancer detection and treatment… A novel molecular pathway in cancer… antigens that are suitable targets for delivery of radioactive and cytotoxic payloads to cancers… Cancers of the reproductive system and gastrointestinal tract… (Cancer Pathology) University of Queensland 1999-00 Post-Doctoral Fellow, Queensland… marker for prostate cancer (PCa). Other members of the KLK family are also emerging as potential…
1991-94 BSc Honours I (Chemistry) University of Queensland, University Medal
1995-99 PhD (Cancer Pathology) University of Queensland
1999-00 Post-Doctoral Fellow, Queensland University of Technology
2001-03 NHMRC CJ Martin/RG Menzies Fellow, Scripps Research Institute, San Diego, CA, USA
2003-05 …
My major research contributions are in the identification and evaluation of molecular targets and biomarkers for cancers of the ovary, pancreas, prostate and bowel. At a molecular level my focus is on cell surface receptors, proteolytic enzymes, intracellular signal transducers, mediators of metabol …
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Using published datasets, and tissue donated by Brisbane breast cancer patients, we're trying to… Post-transcriptional regulation of the breast cancer susceptibility gene BRCA1 by Hu Antigen-R… Development of new theranostic agents for metastatic breast cancer surveillance and treatment… Molecular validation of autofluorescence and narrow band imaging of oral cancer resection margins… Most of the time, treatments for early breast cancer successfully prevent metastatic spread, but… Biomarkers of triple-negative breast cancer progression and response to therapy… cancer. Based at Brisbane’s Translational Research Institute, she was recruited by Mater Research… BRCA1 is a breast cancer susceptibility gene that is down-regulated in the majority of cases of…
Dr Jodi Saunus is a senior fellow who specialises in translational research on metastatic breast cancer. Based at Brisbane’s Translational Research Institute, she was recruited by Mater Research in 2022 to help facilitate patient-focused research at the interface of biomedical R&D and clinical pra …
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development of skin cancers, including melanomas. Over the past 10 years a genetic factors have also been… Histone Deacetylase Inhibition as a Treatment of TRAIL-Resistant Cancers… Preclinical development of combinations with CHK1 inhibitors in melanoma and lung cancer… Targeting defective cell cycle checkpoints in cancers, particularly melanoma… , particularly progression into mitosis. These mechanisms are often mutated in cancers and are likely to… levels of H3K9 modification and HP1 binding in human cancer cells and found only minor effects on H3K9…
Professor Gabrielli completed his undergraduate education at James Cook University in Townsville and PhD at La Trobe University in Melbourne. After two postdoctoral positions in the USA in the emerging field of cell cycle regulation, he was recruited to establish his own independent research at the …
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Global optimization of somatic variant identification in cancer genomes with a global community challenge… Developing software to support Cancer Genomics… Long-read genetic and epigenetic profiling in lung cancer for precision medicine… -matched non-cancer genomes.Results: Through analysis of whole-genome sequence data, we found…
Dr Ewing leads the Translational Bioinformatics Group at the Mater Research Institute - UQ, located at the Translational Research Institute (TRI). His research interests follow a common theme of developing and applying computational methods to investigate genomic mutation in evolutionary and disease …
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. New developments have led to a resurgence in interest in NK-cells in cancer. However, the underlying… What changes are needed to the current direction and interpretation of clinical cancer research to meet the needs of the 21st century?… in diffuse large B-cell lymphoma (Cancer Council Queensland grant administered by PAH)… , including a Fellowship in malignant haematology at Princess Margaret Cancer Centre, Toronto. He was… . However, there are limited reports of persistence, tumor-homing and clinical efficacy in cancer patients…
Maher Gandhi received his medical degree in the UK in 1989, and then trained as a haematologist, including a Fellowship in malignant haematology at Princess Margaret Cancer Centre, Toronto. He was awarded a PhD in immunology at Cambridge University under Patrick Sissons. In 2003 he moved to Brisbane …
The research of the Blood Cancer Research Laboratory aims to understand the basis of lymphoma; to devise new treatments which are less toxic and more effective; to establish new biomarkers which will help determine the most effective treatment strategies and to monitor response and relapse and under …
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Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth… Blood cancer… lung cancer specimens. In summary, we describe novel non-cell autonomous mechanisms by which the…
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NK cells and cancer immunoediting… Control of haematological cancers by Natural Killer cells… Dr Camille Guillerey is a Senior Research Officer in the Cancer Immunotherapies laboratory at… The Toll-like receptor 3 (TLR3) agonist poly(I:C) is a promising adjuvant for cancer vaccines due…
Dr Camille Guillerey is a Senior Research Officer in the Cancer Immunotherapies laboratory at Mater Research. She leads a small team of researchers and students.
Dr Guillerey completed her PhD in Immunology at the Pasteur Institute of Paris, France. In 2014, she moved to Australia to study Cancer I …
Dr Guillerey has authored 28 publications, and has received more than $1,7M in competitive funding from NHMRC, Cancer Australia, Cure Cancer Australia. Leukaemia Foundation and the Children Hospital Foundation. Through this research, Dr Guillerey has made integral contributions to improve knowledge …
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New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways… It glows, it goes - a targeted contrast agent for fluorescence guided ovarian cancer surgery… Many cancers are dependent on inappropriate activation of epidermal growth factor receptor (EGFR…
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Numerical and functional assessment of blood dendritic cells in prostate cancer patients… PiggyBac transposon UCB-CAR19-NK cells: a novel off-the-shelf cellular immunotherapy for children with CD19+ blood cancers… Year in 1998. She then undertook a postdoctoral position at Imperial Cancer Research Fund, London (now… BACKGROUND. Prostate cancer is one of the leading causes of cancer deaths in males and there are…
A/Prof Kristen Radford is a Senior Research Fellow and NHMRC CDA Level 2 fellow. She completed her PhD in 1997 from the University of Newcastle, NSW and was awarded NSW Young Australian of the Year in 1998. She then undertook a postdoctoral position at Imperial Cancer Research Fund, London (now Canc …
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Concise review: Humanized models of tumor immunology in the 21st century: Convergence of cancer research and tissue engineering… cancer bone metastasis (NHMRC Project Grant administered by QUT)… Skeletal metastases present a major clinical challenge for prostate cancer patient care, inflicting…