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Evaluation of cell cycle arrest in estrogen responsive MCF-7 breast cancer cells: Pitfalls of the MTS assay… ACRF Cancer Ultrastructure and Function Facility… cancers, levels of ZO-1 are typically down-regulated, leading to increased motility. Here we report…
I am a clinician scientist and academic leader with research in melanoma cell biology and experimental melanoma therapy. I received my degree in medicine from the University of Heidelberg, Germany (1990-1998). I graduated summa cum laude with a PhD in Cell Biology from the University of Heidelberg ( …
Using cutting-edge technology, including real-time cell cycle imaging in 3D culture and in vivo, my team studies the role of dynamic melanoma heterogeneity in melanomagenesis with the goal to develop novel therapeutic approaches by simultaneously targeting different tumor cell subpopulations. My lab …
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cancer growth. In this study, we will investigate how the tumours are growing more rapidly in the mice with low blood sulfate levels.… RNA interference for the treatment of cervical cancers: Solving the delivery and efficacy issues… Novel therapeutic targets for HPV-driven cancers (Cancer Council Queensland grant administered by Griffith University… developing effective adoptive cellular immunotherapy for vital infections and cancer.…
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High-grade gliomas are the most aggressive forms of brain cancer, with only 50% of patients… Nuclear factor one transcription factors as epigenetic regulators in cancer… focus on these disorders. Moreover, as the transcriptional landscape of many cancers resembles that of… of mRNAs defined predominant pathways in protein synthesis, oxidative phosphorylation, cancer…
I graduated from The University of Tasmania, and received my PhD in Developmental Biology from The University of Queensland in 2003. My PhD, performed at the Institute for Molecular Bioscience with Prof. Melissa Little, centred on understanding the cellular and molecular mechanisms underlying embryo …
The human brain is an incredibly complex organ, consisting of over 100 billion neurons, and even more glial cells. Further adding to this complexity is the fact that there are a wide variety of distinct neuronal subpopulations within the brain, each with different morphological characteristics, neur …
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