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Measuring performance in skin cancer practice: the SCARD initiative… Although dermoscopy has been primarily designed for aiding the in vivo diagnosis of skin tumors…
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The overall aim of this proposal is to understand the cellular mechanisms that maintain skin… Does the nature of residual immune function explain the differential risk of non-melanoma skin… Deciphering novel control mechanisms in the skin… treat skin cancer in immune-suppressed solid organ transplant recipients. Q2361 is a first-in-class… Squamous Cell Carcinoma (SCC) is a type of non-melanoma skin cancer prevalent in immune-suppressed…
Associate Professor James Wells leads the Novel Cancer Therapeutics Group at Frazer Institute and is the Director of Immunology at the Dermatology Research Centre, University of Queensland. He is also the Vice President of the Molecular and Experimental Pathology Society of Australasia (MEPSA), and …
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Development of a Checklist Tool to Assess the Quality of Skin Lesion Images Acquired by Consumers Using Sequential Mobile Teledermoscopy… Artificial Intelligence and 3D imaging of the total skin surface in Australians with skin of colour… dermatology image data. Dr Betz-Stablein is a member of the International Skin Imaging Colaboration AI… Having many melanocytic naevi or 'moles' on the skin is the strongest predictor of melanoma; thus…
Dr Brigid Betz-Stablein is a Postdoctoral Research Fellow based at based at Dermatology Research Centre at the Diamentina Institute. She completed her PhD in Biostatistics in 2014 at Massey University, New Zealand. Prior appointments include a postdoctoral fellowship at QIMR Berghofer, and firstly a …
Naevi, commonly known as moles, are the strongest risk factor of melanoma, and additionally can be precursor lesions to melanomas. There is currently little knowledge of how naevi change over time with very few longitudinal studies in the general population. Dr Brigid Betz-Stablein applies her stati …
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We aim to identify where exactly in the epithelium (skin and mucosa) vaccines need to be delivered… Hpv16 E7 Transgenic Skin Is Not Rejected in E7 Immunized Mice… Preclinical development of Q2361, a transforming new drug for skin cancer prevention in organ transplant recipients… Dry-coated microprojections can deliver vaccine to abundant antigen-presenting cells in the skin…
Professor Ian Frazer is a clinician scientist, trained as a clinical immunologist in Scotland. As a professor at the University of Queensland, he leads a research group working at TRI in Brisbane, Australia on the immunobiology of epithelial cancers. He is recognised as co-inventor of the technology …
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Murine HPV16 E7-expressing transgenic skin effectively emulates the cellular and molecular features of human high-grade squamous intraepithelial lesions… Is there really a viral cause for skin cancer?… and skin cancer. In his time in the Frazer lab, he developed an interest in bioinformatics analyses… hyperproliferative epithelium. Here we examine keratin gene expression profile in skin from mice expressing…
Dr. Kelvin Tuong is a Senior Research Fellow/Group Leader at the Ian Frazer Centre for Children’s Immunotherapy Research (IFCCIR), Child Health Research Centre. He is interested in single-cell analysis of immune cells and harnessing adaptive immune receptors for understanding immune cell development …
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Expression of HPV16-E7 oncoprotein in skin exacerbates the contact hypersensitivity response to DNCB… Skin immune sentinels: roles and functions of immunoregulatory T cells in HPV16 skin infection in mice… skin grafts expressing the same antigens. In humans, clinical trials have reported successful…
After receiving a PhD on immune regulation from La Sorbonne Universitas in France, Anne-Sophie joined Prof. Ian Frazer’s lab in Australia where she led a highly successful and independent research program on the mechanisms of immune tolerance in human papillomavirus (HPV)-associated lesions in mic …
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The role of CXCR3 and its chemokine ligands in skin disease and cancer… skin resulting from infections or autoimmune disease drives expression of CXCL9/10/11 and the…
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Real-time PCR quantification of the canine filaggrin orthologue in the skin of atopic and non-atopic dogs: A pilot study… observed by others in terms of both melanin content and tyrosinase (TYR) activity when comparing skin…
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Destructive and topical treatments of skin lesions in organ transplant recipients and relation to skin cancer… disease, especially skin cancer and cardiovascular disease. Dr Miura is currently leading projects to… Various treatments of keratotic skin lesions and early skin cancers are performed in organ…
Dr Miura's research focus is the role of nutrition and dietary intake in prevention of chronic disease, especially skin cancer and cardiovascular disease. Dr Miura is currently leading projects to studying nutritional status and dietary intake among heart transplant recipients. Her research areas al …
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Regulation of CD8+ T cells in the skin and implications for the development of squamous cell carcinoma… Immune signatures as diagnostic tools for suspicious skin rashes… respiratory tract (influenza A virus, IAV) and the skin surface (Rift Valley Fever virus, RVFV), work that led… enhanced differentiation and function of CD8 memory T cells in the skin. Here, we demonstrate that…
I am an enthusiastic immunologist with strong background in molecular biology techniques, including transcriptional profiling and vaccine development (Cruz JL et al., J Virol, 2013; Cruz JL et al., PloS Pathogens, 2011). I have been developing my professional, research and project management skills, …
Publication Quality
To date, I have published 24 indexed journal articles, with 2 publications in the top 5% and 1 publication in the top 10% most cited publications worldwide (field-weighted) (SciVal, May 2022). I am the first (5/24) or co-first (3/24) author on 40% of my papers and senior (last) …