Protease Activated Receptor 2 : A New Drug Target For Inflammatory Diseases and Cancer (2009–2012)

Abstract:
A new class of proteins (Protease Activated Receptors) has been found on the surfaces of many different types of cells. They are believed to be natural sensors that respond to traces of degradative enzymes called proteases. This project will create and evaluate new drugs for one of these receptors thought to regulate inflammatory diseases (e.g. arthritis, inflammatory bowel disease, asthma, pancreatitis) and cancers, while providing a better understanding of a new mechanism of immune defence.
Grant type:
NHMRC Project Grant
Researchers:
  • NHMRC Snr Principal Research Fellow
    Institute for Molecular Bioscience
    Affiliated Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science
  • Academic Title-Associate Professor
    Princess Alexandra Hospital Southside Clinical Unit
    Faculty of Medicine
  • Senior Research Fellow
    Institute for Molecular Bioscience
Funded by:
National Health and Medical Research Council