NR1F (ROR) nuclear hormone receptors and metabolism: insights into the control of lipid homeostasis.

Abstract:: ROR is a member of a gene family, that regulates reproduction, endocrine physiology, and metabolism, and are important in human health. ROR function remains illusive. However, it is expressed in liver, fat and muscle, tissues that (i) modulate blood lipids, insulin sensitivity and energy balance, and (ii) have an important role in diabetes and obesity. Understanding ROR function in metabolism provides the opportunity for the discovery of new pathways that ameliorate metabolic disease.
Grant type:: NHMRC Project Grant
Funded by:: National Health and Medical Research Council

The University of Queensland