Multiphoton microscopy of living animals as a tool for immunology and cell biology studies (2009–2010)

Abstract:
This application is for a single item of equipment, a multiphoton microscope with split beam scanning capacity designed particularly for rapid imaging of living animal tissues to maintain the examination as physiologically relevant as practical and to allow repeated examinations of the same living animal over time. Aim is to enable observation of interaction over time between tumour cells, immune cells, and host stroma which will significantly advance our understanding of these interactions at the cellular and sub-cellular level. Outcome will be better insights into the physiology and pathophysiology of the immune system and of regulation of cell growth and division, which may underpin the development of new therapy for disease.
Grant type:
ARC Linkage Infrastructure, Equipment and Facilities
Researchers:
  • Professor
    Faculty of Medicine
    Affiliate Professor
    The University of Queensland Diamantina Institute
    Faculty of Medicine
    Affil Professorial Research Fellow
    Institute for Molecular Bioscience
  • Principal Research Fellow
    The University of Queensland Diamantina Institute
    Faculty of Medicine
  • Professor
    School of Pharmacy
    Faculty of Health and Behavioural Sciences
    Professor
    Mater Research Institute-UQ
    Faculty of Medicine
Funded by:
Australian Research Council