Molecular, genetic and cellular analysis of melanisation in human pigmentation (2010–2012)

Variation in human pigmentation skin, eye and hair colour and skin cancer susceptibility, are determined by genes that control melanisation. This ongoing project studies, in combination, the molecular, genetic and cellular basis of melanogenesis. Our studies take unique advantage of cultures of human cells selected based on pigmentation genotype and/or phenotype. Gene variations are correlated with function using live cell imaging, electron microscopy and biochemical analysis. The results will explain at a molecular level, pigmentary characteristics of individuals. Prediction and forensic diagnosis of photosensitivity and cancer risk will be key outcomes of this work.
Grant type:
ARC Discovery Projects
  • Principal Research Fellow
    The University of Queensland Diamantina Institute
    Faculty of Medicine
    Affiliate Associate Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science
  • NHMRC Leadership Fellow - GL
    Institute for Molecular Bioscience
    Affiliated Professor
    School of Biomedical Sciences
    Faculty of Medicine
Funded by:
Australian Research Council