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The role of subgenomic non-coding viral RNA in flavivirus pathogenicity (2010–2013)

Abstract:
Flaviviruses are transmitted by insects and pose a serious health threat to the Australian population. They can cause fever syndromes, encephalitis and death. We aim at better understanding of how these viruses cause disease. We are particularly interested in elucidating the role of small non-coding nucleic acid produced by flaviviruses in the viral pathogenicity. Ultimately, this deeper understanding should lead to the development of effective vaccines and antiviral therapies.
Grant type:
NHMRC Project Grant
Researchers:

  • Professor Alexander Khromykh

    Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science

  • Professor Paul Young

    Professor, Research Development
    Office of the Deputy Vice-Chancellor (Research and Innovation)
    Affiliate Professor
    Australian Institute for Bioengineering and Nanotechnology

  • Professor Matt Sweet

    NHMRC Leadership Fellow - GL
    Institute for Molecular Bioscience
    Affiliate NHMRC Leadership Fellow
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
National Health and Medical Research Council