Investigating the role of the NR4A nuclear receptor family in melanocyte function and tumorigenesis (2010–2012)

Abstract:
Individuals with red hair and fair skin have a considerably greater risk of developing melanoma and non-melanoma skin cancer. Understanding the relationship that genes such as MCR1 and NR4As have to skin functions such as tanning and protection from UV damage, will provide a greater insight into melanoma susceptibility and progression. Furthermore, understanding the role that abnormal NR4A regulation plays in melanoma formation will aid in the identification of new therapeutic targets.
Grant type:
NHMRC Project Grant
Researchers:
  • Professorial Research Fellow
    Institute for Molecular Bioscience
    Affiliate Professor
    School of Biomedical Sciences
    Faculty of Medicine
  • Principal Research Fellow
    The University of Queensland Diamantina Institute
    Faculty of Medicine
    Affiliate Associate Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
National Health and Medical Research Council