Regulation of Bone Dynamics by Osteal Tissue Macrophages (Osteomacs) (2010–2013)

Abstract:
There is a high demand for effective treatments to rebuild and replace lost bone in fracture repair and osteoporosis. We have described a discrete population of macrophages (classically immune defense cells) within the specialized tissues that line bones. We have shown that these bone tissue macrophages have a novel role in promoting the formation of new bone. This project grant will extend these observations and identify the clinical potential of bone tissue macrophages to treat bone disease.
Grant type:
NHMRC Project Grant
Researchers:
  • Professor
    Mater Research Institute-UQ
    Faculty of Medicine
  • Honorary Fellow
    Mater Research Institute-UQ
    Faculty of Medicine
  • Professorial Research Fellow - GL
    Institute for Molecular Bioscience
    Affiliated Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
National Health and Medical Research Council