DCC-Robo interactions cooperate to regulate callosal axon guidance

Abstract:: In order for the brain to function, the correct connections between neurons must be formed during development. These connections, formed by the axonal processes of neurons, are able to find their synaptic targets by sensing molecular cues within the brain that guide them, by attraction or repulsion, to their target. This proposal investigates how attractive and repulsive signals are received and integrated in neurons to enable axons to find their targets in the brain.
Grant type:: NHMRC Project Grant
Funded by:: National Health and Medical Research Council