Suppression of high-grade glioma by Nfib overexpression (2011–2012)

Abstract:
High-grade gliomas are the most aggressive forms of brain cancer, with only 50% of patients surviving their first year post-diagnosis. At present there is no cure for this disease and current treatments do not significantly delay tumour progression. Nuclear Factor One ¿B (Nfib) is a transcription factor that may prevent tumour growth through cellular differentiation. We will investigate the role of Nfib in the pathogenesis of high-grade glioma and its potential as a therapeutic target.
Grant type:
Cancer Council Queensland
Researchers:
  • Deputy Director (Research)
    Queensland Brain Institute
    Affiliate Professor
    School of Biomedical Sciences
    Faculty of Medicine
  • Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine
    Director (Research Training)
    Research Strategy and Support (Medicine)
    Faculty of Medicine
    Affiliate Principal Research Fellow
    Queensland Brain Institute
Funded by:
Cancer Council Queensland