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DEVELOPMENT OF A NOVEL BIOMATERIAL FOR BONE TISSUE ENGINEERING (2003)

Abstract:
Tissue engineering of bone is emerging as a viable therapy for treating large defects in load-bearing bone. We wish to develop methods for combining novel heparan sulphate molecules (known to deliver growth factors to cell surfaces and thereby cause changes in bone cell phenotype) with load-bearing, macro-porous, biodegradable mineral/polymer biomaterials. Through the study of release profiles, protein adsorption and cell responses to these derivatised biomaterials, a novel approach to bone replacement materials can be developed. ''
Grant type:
ARC Discovery Projects
Researchers:

  • Professor Matt Trau

    ARC Australian Laureate Fellow
    Australian Institute for Bioengineering and Nanotechnology
    ARC Laureate Fellow
    School of Chemistry and Molecular Biosciences
    Faculty of Science

  • Professor Lisbeth Grondahl

    Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science

  • Professor Simon Cool

    Professor & Director of UQ Advance
    School of Chemical Engineering
    Faculty of Engineering, Architecture and Information Technology
Funded by:
Australian Research Council