The immunoregulatory domains and binding interactions of human respiratory syncytial virus non-structural proteins

Abstract:: Human respiratory syncytial virus (HRSV) is the leading cause of lower respiratory tract disease in infants and yet there are no vaccines available. HRSV exacerbates disease by interfering with the innate immune response. We aim to establish the mechanism by which this occurs by identifying the cellular-viral protein interactions involved, and by identifying the specific regions of the viral proteins responsible. This information will allow target vaccines and antivirals to be developed.
Grant type:: NHMRC Project Grant
Funded by:: National Health and Medical Research Council

The University of Queensland