Engineering biomimetic lubrication with mucin (2015–2017)
Engineering coatings for water to be an effective lubricant is a significant challenge. We seek to emulate how
nature builds highly lubricating water-rich polymer films on biological surfaces. This will be achieved by
directing the self-assembly of mucin macromolecules onto polymer brushes attached to a substrate, and
then cross-linking the constituents to obtain a hydrated gel-like lubricating coating. This research will provide
new insights on the mechanisms by which mucin-rich fluids lubricate and protect biosurfaces, which is
important to human health, nutrition and well-being. It will also lead to new discoveries for engineering
surface coatings for biomaterials and nanomaterials.