Reaching new heights in high-resolution electron microscopy (2015–2016)

Abstract:
Direct Electron Detection cameras are a recent technological breakthrough delivering one of the greatest single advancements to the field of molecular cryo-EM. The aim of this proposal is to enable a "first of a kind" cryo-EM platform in Australia enabling high-throughput atomic resolution protein structure determination. This will be achieved by integrating a state-of-the-art Gatan K2 Summit Direct Electron Detection camera system into the established ~$15M cryo-EM facility managed by the UQ node of the Australian Microscopy & Microanalysis Facility. This will offer unique and significantly improved capabilities for atomic resolution protein structure analysis, and will support a broad range of projects across the biological sciences.
Grant type:
ARC Linkage Infrastructure, Equipment and Facilities
Researchers:
  • Professorial Research Fellow
    Institute for Molecular Bioscience
  • Senior Lecturer
    School of Chemistry and Molecular Biosciences
    Faculty of Science
    Affiliate Research Fellow
    Institute for Molecular Bioscience
  • Professorial Research Fellow
    Institute for Molecular Bioscience
    Affiliate Professor
    School of Biomedical Sciences
    Faculty of Medicine
  • Head of School
    School of Chemistry and Molecular Biosciences
    Faculty of Science
    Affiliated Professor
    Institute for Molecular Bioscience
    Affiliate Professor
    Australian Institute for Bioengineering and Nanotechnology
  • VC's Research and Teach Fellow
    Australian Institute for Bioengineering and Nanotechnology
    Vice-Chancellor's Res & Tech Fellow
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
Australian Research Council