Evolution of genome architecture

Abstract:: Our genome sequence is arranged into higher order structures that enable coordinated gene expression. The appropriate expression of genes in time and space is necessary to produce the multitude of cell types that make up a multicellular organism. Yet, to date, genome topology is poorly explored especially between species. The project aims to understand how changes to genome architecture over evolutionary time are linked to the diversity of animal morphology. It involves comparisons of the 3D structure of genomes in divergent species. These findings are expected to inform the underlying principles of gene regulation in animals and illuminate how species have evolved.
Grant type:: ARC Discovery Early Career Researcher Award
Funded by:: Australian Research Council

The University of Queensland