The University of Queensland

The identification of novel genetic loci and pathways associated with ALS through interrogation of multiple integrated genomics data sets (2017–2022)

Abstract:

In 85% of amyotrophic lateral sclerosis (ALS) cases the causative mutation is not known. Here, we will use novel genomics and molecular methods to improve diagnosis and enhance the understanding of severe neuronal degeneration. This includes the characterisation of patient neurons to fast-track genetic discovery with patient-specific treatment assays. We envisage an expanded diagnostic and treatment suite that will provide answers for all ALS patients for whom there is no known genetic cause.

Grant type:

NHMRC Early Career Fellowships

Researchers:

• 

  Dr Fleur Garton

  NHMRC Early Career Fellow
  

  Institute for Molecular Bioscience

Funded by:

National Health and Medical Research Council