Investigating changes in lamellar proteins during sepsis-associated laminitis using open-flow microprefusion (2018)

Abstract:
Sepsis-associated laminitis is a major complication of infectious disease in horses. Despite intensive research its cause remains unclear and treatment elusive. Recently, phosphorylation of ribosomal protein S6 (rpS6) was suggested as the earliest event in laminitis development. Combining experimental laminitis induction, sampling using lamellar open flow-microperfusion and western blot analysis, this study will assess phosphorylation and dephosphorylation of lamellar proteins during laminitis.
Grant type:
UQ Early Career Researcher
Researchers:
Funded by:
University of Queensland