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Advancing the visualisation and quantification of nephrons with MRI (2022–2025)

Abstract:
This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body¿TM)s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are innovative semi-automated nephron visualisation and quantitation tools that enable efficient renal phenotyping. Techniques tailored to widely accessible preclinical research scanners are expected to accelerate research into genetic and environmental factors affecting kidney microstructure in embryonic and post-natal life.
Grant type:
ARC Discovery Projects
Researchers:

  • Dr Shakes Chandra

    Senior Lecturer
    School of Electrical Engineering and Computer Science
    Faculty of Engineering, Architecture and Information Technology

  • Dr Nyoman Kurniawan

    Research Fellow
    Centre for Advanced Imaging
    Australian Institute for Bioengineering and Nanotechnology
Funded by:
Australian Research Council