The University of Queensland

Opening Up Access to L-Sugars through a Synergy of Experiment and Theory (2022–2025)

Abstract:

This project aims to address a major bottleneck in the science of carbohydrates by developing the first broad-scope synthetic routes to L-sugars. L-sugars are critical components of many biologically and commercially significant molecules, but knowledge of their functional roles is impeded by the fact that most L-sugars are expensive or difficult to make. This project expects to develop expeditious routes to L-sugars via an innovative combination of synthetic and theoretical chemistry. Expected outcomes include a markedly increased capacity to access pure samples of L-sugar-based biomolecules, as needed for studying their biological functions. Significant benefits in the development of vaccines, diagnostics and biomaterials are anticipated.

Grant type:

ARC Discovery Projects

Researchers:

• 

  Professor Vito Ferro

  Professor
  

  School of Chemistry and Molecular Biosciences

  Faculty of Science

• 

  Professor Elizabeth Krenske

  Professor
  

  School of Chemistry and Molecular Biosciences

  Faculty of Science

Funded by:

Australian Research Council