Chemical mimics of bioactive protein surfaces (2006–2011)

Abstract:
Proteins are the key functional components that define life, ageing, disease and death. Their uses in medicine, science and industry are extremely limited by their complexity, high costs, chemical instability and low bioavailability. This program will develop new chemical technology for creating simpler, smaller, cheaper, more stable and more bioavailable molecules that can execute selected functions of proteins. The approach involves devising stable new molecular shapes to mimic structural components of proteins (helices, turns, strands, and combinations), and using them as tools to interrogate biological systems and to explore prospective applications as new pharmaceuticals, diagnostics, vaccines, and nanomaterials.
Grant type:
ARC Federation Fellowships
Researchers:
  • Professiorial Research Fellow - GL
    Institute for Molecular Bioscience
    Affiliated Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
Australian Research Council