Histone deacetylase inhibitors can inhibit tumour growth via induction of an anti-tumour immune response (2008–2009)
Conventional anti-cancer therapies have many debilitating side effects, including suppressing the immune system which has demonstrated anti-cancer activity. New chemotherapeutic drugs are more targeted with fewer side effects. Consequently, it is possible to combine the benefits of chemotherapy and immunotherapy. If successful, we will determine how anti-cancer treatment with these drugs can be optimised to improve curative outcomes.