Professor Rod Minchin

Chair of Molecular Pharmacology

School of Biomedical Sciences
Faculty of Medicine
r.minchin@uq.edu.au
+61 7 334 61620

Overview

Professor Minchin received his PhD from the Department of Pharmacology at the University of Western Australia before undertaking post-doctoral studies at the National Cancer Institute in Washington DC. His major work was on pulmonary toxicology of anti-cancer drugs and chemical carcinogenesis. He returned as a QEII Fellow to the University of New South Wales to investigate polyamine transport in the lung. Eventually, he returned to the University of Western Australia as a teaching and research academic where his interest in arylamine N-acetyltransferases and gene therapy developed. Currently, Professor Minchin is the Chair of Molecular Pharmacology at the University of Queensland and is Head, Laboratory for Moleculkar and Cellular Pharmacology in the School of Biomedical Sciences

Research Interests

  • •Cellular activity to arylamine N-acetyltransferase, its subcellular localisation and modulation of growth and resistance
  • •Role of sulfotransferases in neurodegenerative diseases
  • •Interaction of nanomaterials with macromolecules and cells

Research Impacts

The Laboratory for Molecular and Cellular Pharmacology investigates the effects that drugs and other chemicals exert in human health and disease. Our research aims to identify biochemical pathways and cellular processes that may be targets for novel drug development and use. The Laboratory focuses on several cellular proteins (arylamine N-acetyltransferases and cytosolic sulfotransferases) that have a central role in cancer initiation and progression as well as neurological diseases such as Parkinsons. We also investigate the interaction of nanoparticles and nanomaterials with proteins and cells in order to better understand their potential future pharmacological applications.

Qualifications

  • Doctor of Philosophy, W.Aust
  • Bachelor of Science (Hons), W.Aust

Publications

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Grants

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Supervision

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Available Projects

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Publications

Book Chapter

  • Butcher, Neville J., Li, Pengcheng, Wang, Lili and Minchin, Rodney F. (2018). Human Arylamine N-Acetyltransferase Type 1. Arylamine N-acetyltransferases in Health and Disease. (pp. 91-107) Singapore: World Scientific Publishing. doi: 10.1142/9789813232013_0004

  • Mortimer, G. M. and Minchin, R. F. (2016). Nanotoxicology and nanovaccines. Micro and nanotechnology in vaccine development . (pp. 373-392) edited by Mariusz Skwarczynski and Istvan Toth. Oxford, United Kingdom: Elsevier . doi: 10.1016/B978-0-323-39981-4.00020-8

  • Martin, D., Minchin, R. F., Belkina, M., Milev, A. and Kannangara, G. S. Kamali (2011). Toxicity and regulatory perspectives of carbon nanotubes. Polymer-carbon nanotube composites : Preparation, properties and applications. (pp. 621-653) edited by Tony McNally and Petra Pötschke. Cambridge, U.K.: Woodhead Publishing. doi: 10.1533/9780857091390.2.621

  • Butcher, Neville J. and Minchin, Rodney F. (2008). Arylamine N-Acetyltransferases. Encyclopedia of cancer. (pp. 255-257) edited by Manfred Schwab. Berlin, Germany: Springer Verlag.

  • Butcher, N. J. and Minchin, R. F. (2005). Arylamine N-Acetyltransferase Gene Polymorphism. Encyclopedia of Medical Genomics and Proteomics. (pp. 79-83) edited by Jurgen Fuchs and Maurizio Podda. New York: Marcel Dekker.

Journal Article

Conference Publication

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

Completed Supervision

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.