The University of Queensland

Human Arylamine N-Acetyltransferase Type 1

Butcher, Neville J., Li, Pengcheng, Wang, Lili and Minchin, Rodney F. (2018). Human Arylamine N-Acetyltransferase Type 1. In Arylamine N-acetyltransferases in Health and Disease (pp. 91-107) Singapore: World Scientific Publishing. doi:10.1142/9789813232013_0004

Nanotoxicology and nanovaccines

Mortimer, G. M. and Minchin, R. F. (2016). Nanotoxicology and nanovaccines. In Mariusz Skwarczynski and Istvan Toth (Ed.), Micro and nanotechnology in vaccine development (pp. 373-392) Oxford, United Kingdom: Elsevier . doi:10.1016/B978-0-323-39981-4.00020-8

Toxicity and regulatory perspectives of carbon nanotubes

Martin, D., Minchin, R. F., Belkina, M., Milev, A. and Kannangara, G. S. Kamali (2011). Toxicity and regulatory perspectives of carbon nanotubes. In Tony McNally and Petra Pötschke (Ed.), Polymer-carbon nanotube composites : Preparation, properties and applications (pp. 621-653) Cambridge, U.K.: Woodhead Publishing. doi:10.1533/9780857091390.2.621

Arylamine N-Acetyltransferases

Butcher, Neville J. and Minchin, Rodney F. (2008). Arylamine N-Acetyltransferases. In Manfred Schwab (Ed.), Encyclopedia of cancer 2nd ed. (pp. 255-257) Berlin, Germany: Springer Verlag.

Arylamine N-Acetyltransferase Gene Polymorphism

Butcher, N. J. and Minchin, R. F. (2005). Arylamine N-Acetyltransferase Gene Polymorphism. In Jurgen Fuchs and Maurizio Podda (Ed.), Encyclopedia of Medical Genomics and Proteomics (pp. 79-83) New York: Marcel Dekker.

Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex

Wang, Lili, Minchin, Rodney F., Essebier, Patricia J. and Butcher, Neville J. (2019) Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex. The International Journal of Biochemistry & Cell Biology, . doi:10.1016/j.biocel.2019.03.002

The MBNL/CELF splicing factors regulate cytosolic sulfotransferase 4A1 protein expression during cell differentiation

Idris, Misgana, Butcher, Neville J and Minchin, Rodney F (2019) The MBNL/CELF splicing factors regulate cytosolic sulfotransferase 4A1 protein expression during cell differentiation. Drug Metabolism and Disposition, 47 3: 314-319. doi:10.1124/dmd.118.085290

Allosteric regulation of arylamine N-acetyltransferase 1 by adenosine triphosphate

Minchin, Rodney F., Rosengren, K. Johan, Burow, Rachel and Butcher, Neville J. (2018) Allosteric regulation of arylamine N-acetyltransferase 1 by adenosine triphosphate. Biochemical Pharmacology, 158 153-160. doi:10.1016/j.bcp.2018.10.013

Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance

Minchin, Rodney F. and Butcher, Neville J. (2018) Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance. BMC Genomics, 19 1: 513. doi:10.1186/s12864-018-4894-4

Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability

Wang, LiLi, Minchin, Rodney F and Butcher, Neville J (2018) Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability. PLoS One, 13 3: e0193560. doi:10.1371/journal.pone.0193560

Sulfotransferase 1A3/4 copy number variation is associated with neurodegenerative disease

Butcher, N. J., Horne, M. K., Mellick, G. D., Fowler, C. J., Masters, C. L. and Minchin, R. F. (2017) Sulfotransferase 1A3/4 copy number variation is associated with neurodegenerative disease. Pharmacogenomics Journal, 18 2: 209-214. doi:10.1038/tpj.2017.4

Role for human arylamine N-acetyltransferase 1 in the methionine salvage pathway

Witham, Katey L., Minchin, Rodney F. and Butcher, Neville J. (2017) Role for human arylamine N-acetyltransferase 1 in the methionine salvage pathway. Biochemical Pharmacology, 125 93-100. doi:10.1016/j.bcp.2016.11.015

Cryptic epitopes and functional diversity in extracellular proteins

Mortimer, Gysell M. and Minchin, Rodney F. (2016) Cryptic epitopes and functional diversity in extracellular proteins. International Journal of Biochemistry and Cell Biology, 81 Part A: 112-120. doi:10.1016/j.biocel.2016.10.020

Release of bioactive peptides from polyurethane films in vitro and in vivo: Effect of polymer composition

Zhang, Jing, Woodruff, Trent M., Clark, Richard J., Martin, Darren J. and Minchin, Rodney F. (2016) Release of bioactive peptides from polyurethane films in vitro and in vivo: Effect of polymer composition. Acta Biomaterialia, 41 264-272. doi:10.1016/j.actbio.2016.05.034

Stable non-covalent labeling of layered silicate nanoparticles for biological imaging

Mortimer, Gysell M., Jack, Kevin S., Musumeci, Anthony W., Martin, Darren J. and Minchin, Rodney F. (2016) Stable non-covalent labeling of layered silicate nanoparticles for biological imaging. Materials Science and Engineering C, 61 674-680. doi:10.1016/j.msec.2015.12.047

Protein corona formation in bronchoalveolar fluid enhances diesel exhaust nanoparticle uptake and pro-inflammatory responses in macrophages

Shaw, Catherine A., Mortimer, Gysell M., Deng, Zhou J., Carter, Edwin S., Connell, Shea P., Miller, Mark R., Duffin, Rodger, Newby, David E., Hadoke, Patrick W. F. and Minchin, Rodney F. (2016) Protein corona formation in bronchoalveolar fluid enhances diesel exhaust nanoparticle uptake and pro-inflammatory responses in macrophages. Nanotoxicology, 10 7: 981-991. doi:10.3109/17435390.2016.1155672

Drug delivery: unravelling the stealth effect

Butcher, Neville J., Mortimer, Gysell M. and Minchin, Rodney F. (2016) Drug delivery: unravelling the stealth effect. Nature Nanotechnology, 11 4: 310-311. doi:10.1038/nnano.2016.6

A bag of cells approach for antinuclear antibodies HEp-2 image classification

Wiliem, Arnold, Hobson, Peter, Minchin, Rodney F. and Lovell, Brian C. (2015) A bag of cells approach for antinuclear antibodies HEp-2 image classification. Cytometry. Part A, 87 6: 549-557. doi:10.1002/cyto.a.22597

Effects of human arylamine N-acetyltransferase I knockdown in triple-negative breast cancer cell lines

Tiang, Jacky M., Butcher, Neville J. and Minchin, Rodney F. (2015) Effects of human arylamine N-acetyltransferase I knockdown in triple-negative breast cancer cell lines. Cancer Medicine, 4 4: 565-574. doi:10.1002/cam4.415

The role of lysine100 in the binding of acetylcoenzyme A to human arylamine N-acetyltransferase 1: Implications for other acetyltransferases

Minchin, Rodney F and Butcher, Neville J (2015) The role of lysine100 in the binding of acetylcoenzyme A to human arylamine N-acetyltransferase 1: Implications for other acetyltransferases. Biochemical Pharmacology, 94 3: 195-202. doi:10.1016/j.bcp.2015.01.015

Nanoparticles-induced inflammatory cytokines in human plasma concentration manner: An ignored factor at the nanobio-interface

Tirtaatmadja, Nicolin, Mortimer, Gysell, Ng, Eng-Poh, Ahmad, Hacan Ali, Mintova, Svetlana, Serpooshan, Vahid, Minchin, Rodney F and Mahmoudi, Morteza (2015) Nanoparticles-induced inflammatory cytokines in human plasma concentration manner: An ignored factor at the nanobio-interface. Journal of the Iranian Chemical Society, 12 2: 317-323. doi:10.1007/s13738-014-0486-7

Fluoromica nanoparticle cytotoxicity in macrophages decreases with size and extent of uptake

Tee, Nicolin, Zhu, Yingdong, Mortimer, Gysell M., Martin, Darren J. and Minchin, Rodney F. (2015) Fluoromica nanoparticle cytotoxicity in macrophages decreases with size and extent of uptake. International Journal of Nanomedicine, 10 2363-2375. doi:10.2147/IJN.S80655

Expression of the orphan cytosolic sulfotransferase SULT4A1 and its major splice variant in human tissues and cells: dimerization, degradation and polyubiquitination

Sidharthan, Neelima P., Butcher, Neville J., Mitchell, Deanne J. and Minchin, Rodney F. (2014) Expression of the orphan cytosolic sulfotransferase SULT4A1 and its major splice variant in human tissues and cells: dimerization, degradation and polyubiquitination. PLoS One, 9 7: e101520.1-e101520.8. doi:10.1371/journal.pone.0101520

Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro

Stephenson, Rachel, Varamini, Pegah, Butcher, Neville, Minchin, Rodney and Toth, Istvan (2014) Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro. Nanomedicine: Nanotechnology, Biology and Medicine, 10 8: 1799-1808. doi:10.1016/j.nano.2014.06.015

Cryptic epitopes of albumin determine mononuclear phagocyte system clearance of nanomaterials

Mortimer, Gysell M., Butcher, Neville J., Musumeci, Anthony W., Deng, Zhou J., Martin, Darren J. and Minchin, Rodney F. (2014) Cryptic epitopes of albumin determine mononuclear phagocyte system clearance of nanomaterials. ACS Nano, 8 4: 3357-3366. doi:10.1021/nn405830g

Implementation of a Virtual Laboratory Practical Class (VLPC) module in pharmacology education

Cheesman, Matthew J., Chen, Steven, Manchadi, Mary-Louise, Jacob, Teague, Minchin, Rodney F. and Tregloan, Peter A. (2014) Implementation of a Virtual Laboratory Practical Class (VLPC) module in pharmacology education. Pharmacognosy Communications, 4 1: 2-10. doi:10.5530/pc.2014.1.2

Automatic classification of Human Epithelial type 2 cell Indirect Immunofluorescence images using Cell Pyramid Matching

Wiliem, Arnold, Sanderson, Conrad, Wong, Yongkang, Hobson, Peter, Minchin, Rodney F. and Lovell, Brian C. (2014) Automatic classification of Human Epithelial type 2 cell Indirect Immunofluorescence images using Cell Pyramid Matching. Pattern Recognition, 47 7: 2315-2324. doi:10.1016/j.patcog.2013.10.014

Effect of supercritical carbon dioxide on the loading and release of model drugs from polyurethane films: comparison with solvent casting

Zhang, Jing, Martin, Darren J., Taran, Elena, Thurecht, Kristofer J. and Minchin, Rodney F. (2014) Effect of supercritical carbon dioxide on the loading and release of model drugs from polyurethane films: comparison with solvent casting. Macromolecular Chemistry and Physics, 215 1: 54-64. doi:10.1002/macp.201300492

Interaction of human arylamine n-acetyltransferase 1 with different nanomaterials

Deng, Zhou J., Butcher, Neville J., Mortimer, Gysell M., Jia, Zhongfan, Monteiro, Michael J., Martin, Darren J. and Minchin, Rodney F. (2014) Interaction of human arylamine n-acetyltransferase 1 with different nanomaterials. Drug Metabolism and Disposition, 42 3: 377-383. doi:10.1124/dmd.113.055988

Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: Role of D1 receptor-n-methyl-d-aspartate receptor coupling

Sidharthan, Neelima P., Minchin, Rodney F. and Butcher, Neville J. (2013) Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: Role of D1 receptor-n-methyl-d-aspartate receptor coupling. Journal of Biological Chemistry, 288 48: 34364-34374. doi:10.1074/jbc.M113.493239

5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion

Witham, Katey L., Butcher, Neville J., Sugamori, Kim S., Brenneman, Debbie, Grant, Denis M. and Minchin, Rodney F. (2013) 5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion. PLoS One, 8 10: e77923.1-e77923.7. doi:10.1371/journal.pone.0077923

Plasma protein binding of positively and negatively charged polymer-coated gold nanoparticles elicits different biological responses

Deng, Zhou J., Liang, Mingtao, Toth, Istvan, Monteiro, Michael and Minchin, Rodney F. (2013) Plasma protein binding of positively and negatively charged polymer-coated gold nanoparticles elicits different biological responses. Nanotoxicology, 7 3: 314-322. doi:10.3109/17435390.2012.655342

Exocytosis of nanoparticles from cells: Role in cellular retention and toxicity

Sakhtianchi, Ramom, Minchin, Rodney F., Lee, Ki-Bum, Alkilany, Alaaldin M., Serpooshan, Vahid and Mahmoudi, Morteza (2013) Exocytosis of nanoparticles from cells: Role in cellular retention and toxicity. Advances in Colloid and Interface Science, 201-202 18-29. doi:10.1016/j.cis.2013.10.013

Arylamine N-acetyltransferase 1: A novel drug target in cancer development

Butcher, Neville J. and Minchin, Rodney F. (2012) Arylamine N-acetyltransferase 1: A novel drug target in cancer development. Pharmacological Reviews, 64 1: 147-165. doi:10.1124/pr.110.004275

Molecular interaction of poly(acrylic acid) gold nanoparticles with human fibrinogen

Deng, Zhou J., Liang, Mingtao, Toth, Istvan, Monteiro, Michael J. and Minchin, Rodney F. (2012) Molecular interaction of poly(acrylic acid) gold nanoparticles with human fibrinogen. ACS Nano, 6 10: 8962-8969. doi:10.1021/nn3029953

Role of intratumoural heterogeneity in cancer drug resistance: Molecular and clinical perspectives

Saunders, Nicholas A., Simpson, Fiona, Thompson, Erik W., Hill, Michelle M., Endo-Munoz, Liliana, Leggatt, Graham, Minchin, Rodney F. and Guminski, Alexander (2012) Role of intratumoural heterogeneity in cancer drug resistance: Molecular and clinical perspectives. EMBO Molecular Medicine, 4 8: 675-684. doi:10.1002/emmm.201101131

RNAi-mediated knock-down of Arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibition

Tiang, JM, Butcher, NJ, Cullinane, C, Humbert, PO and Minchin, RF (2011) RNAi-mediated knock-down of Arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibition. PLoS One, 6 2: 1-10. doi:10.1371/journal.pone.0017031

Histone deacetylase inhibitors increase human arylamine N-acetyltransferase-1 expression in human tumor cells

Paterson, S, Sin, KL, Tiang, JM, Minchin, RF and Butcher, NJ (2011) Histone deacetylase inhibitors increase human arylamine N-acetyltransferase-1 expression in human tumor cells. Drug Metabolism and Disposition, 39 1: 77-82. doi:10.1124/dmd.110.036202

Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation

Deng, Zhou J., Liang, Mingtao, Monteiro, Michael, Toth, Istvan and Minchin, Rodney F. (2011) Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation. Nature Nanotechnology, 6 1: 39-44. doi:10.1038/NNANO.2010.250

Phosphorylation/dephosphorylation of human SULT4A1: Role of Erk1 and PP2A

Mitchell, Deanne J., Butcher, Neville J. and Minchin, Rodney F. (2011) Phosphorylation/dephosphorylation of human SULT4A1: Role of Erk1 and PP2A. Biochimica et Biophysica Acta - Molecular Cell Research, 1813 1: 231-237. doi:10.1016/j.bbamcr.2010.09.011

Regulation of Mouse Brain-Selective Sulfotransferase Sult4a1 by cAMP Response Element-Binding Protein and Activating Transcription Factor-2

Butcher, Neville J., Mitchell, Deanne J., Burow, Rachel and Minchin, Rodney F. (2010) Regulation of Mouse Brain-Selective Sulfotransferase Sult4a1 by cAMP Response Element-Binding Protein and Activating Transcription Factor-2. Molecular Pharmacology, 78 3: 503-510. doi:10.1124/mol.110.063404

Arylamine N-acetyltransferase 1 gene regulation by androgens requires a conserved heat shock element for heat shock factor-1

Butcher, Neville J. and Minchin, Rodney F. (2010) Arylamine N-acetyltransferase 1 gene regulation by androgens requires a conserved heat shock element for heat shock factor-1. Carcinogenesis, 31 5: 820-826. doi:10.1093/carcin/bgq042

Endosomal disruptors in non-viral gene delivery

Minchin, Rodney F. and Yang, Shu (2010) Endosomal disruptors in non-viral gene delivery. Expert Opinion On Drug Delivery, 7 3: 331-339. doi:10.1517/17425240903512931

Fluorescent layered double hydroxide nanoparticles for biological studies

Musumeci, Anthony W., Mortimer, Gysell M., Butler, Margaret K., Xu, Zhi Ping, Minchin, Rodney M. and Martin, Darren J. (2010) Fluorescent layered double hydroxide nanoparticles for biological studies. Applied Clay Science, 48 1-2: 271-279. doi:10.1016/j.clay.2009.11.008

Small molecule inhibition of arylamine N-acetyltransferase Type I inhibits proliferation and invasiveness of MDA-MB-231 breast cancer cells

Tiang, Jacky M., Butcher, Neville J. and Minchin, Rodney F. (2010) Small molecule inhibition of arylamine N-acetyltransferase Type I inhibits proliferation and invasiveness of MDA-MB-231 breast cancer cells. Biochemical and Biophysical Research Communications, 393 1: 95-100. doi:10.1016/j.bbrc.2010.01.087

Minireview: Nanoparticles for molecular imaging - an overview

Minchin, Rodney F and Martin, Darren J (2010) Minireview: Nanoparticles for molecular imaging - an overview. Endocrinology, 151 2: 474-481. doi:10.1210/en.2009-1012

Cellular uptake of densely packed polymer coatings on gold nanoparticles

Liang, Mingtao, Lin, I-Chun, Whittaker, Michael R., Minchin, Rodney F., Monteiro, Michael J. and Toth, Istvan (2010) Cellular uptake of densely packed polymer coatings on gold nanoparticles. ACS Nano, 4 1: 403-413. doi:10.1021/nn9011237

Synthesis and characterization of dual radiolabeled layered double hydroxide nanoparticles for use in in vitro and in vivo nanotoxicology studies

Musumeci, Anthony W., Schiller, Tara L., Xu, Zhi Ping, Minchin, Rodney F., Martin, Darren J. and Smith, Suzanne V. (2010) Synthesis and characterization of dual radiolabeled layered double hydroxide nanoparticles for use in in vitro and in vivo nanotoxicology studies. The Journal of Physical Chemistry Part C: Nanomaterials and Interfaces, 114 2: 734-740. doi:10.1021/jp905347x

Layered double hydroxide nanoparticles incorporating terbium: applicability as a fluorescent probe and morphology modifier

Musumeci, Anthony W, Xu, Zhi Ping, Smith, Suzanne V, Minchin, Rodney F and Martin, Darren J (2010) Layered double hydroxide nanoparticles incorporating terbium: applicability as a fluorescent probe and morphology modifier. Journal of Nanoparticle Research, 12 1: 111-120. doi:10.1007/s11051-008-9583-9

Differential plasma protein binding to metal oxide nanoparticles

Deng, Zhou J., Mortimer, Gysell, Schiller, Tara, Musumeci, Anthony, Martin, Darren and Minchin, Rodney F. (2009) Differential plasma protein binding to metal oxide nanoparticles. Nanotechnology, 20 45: 455101.1-455101.9. doi:10.1088/0957-4484/20/45/455101

Cytosolic Aryl Sulfotransferase 4A1 Interacts with the Peptidyl Prolyl Cis-Trans Isomerase Pin1

Mitchell, Deanne J. and Minchin, Rodney F. (2009) Cytosolic Aryl Sulfotransferase 4A1 Interacts with the Peptidyl Prolyl Cis-Trans Isomerase Pin1. Molecular Pharmacology, 76 2: 388-395. doi:10.1124/mol.109.055442

Lack of exonic sulflotransferase 4A1 mutations in controls and schizophrenia cases

Lewis, Aaron G. and Minchin, Rodney F. (2009) Lack of exonic sulflotransferase 4A1 mutations in controls and schizophrenia cases. Psychiatric Genetics, 19 1: 53-55. doi:10.1097/YPG.0b013e3283118776

Cellular uptake of self-assembled cationic peptide-DNA complexes: Multifunctional role of the enhancer chloroquine

Yang, Shu, Coles, David J., Esposito, Anna, Mitchell, Deanne J., Toth, Istvan and Minchin, Rodney F. (2009) Cellular uptake of self-assembled cationic peptide-DNA complexes: Multifunctional role of the enhancer chloroquine. Journal of controlled release, 135 2: 159-165. doi:10.1016/j.jconrel.2008.12.015

Regulation of arylamine N-acetyltransferases

Butcher, Neville J., Tiang, Jacky and Minchin, Rodney F. (2008) Regulation of arylamine N-acetyltransferases. Current Drug Metabolism, 9 6: 498-504. doi:10.2174/138920008784892128

The characterization of a novel dendritic system for gene delivery by isothermal titration calorimetry

Coles, Daniel J., Yang, Shu, Minchin, Rodney F. and Toth, Istvan (2008) The characterization of a novel dendritic system for gene delivery by isothermal titration calorimetry. Biopolymers, 90 5: 651-654. doi:10.1002/bip.21019

Changes in consensus arylamine N-acetyltransferase gene nomenclature

Hein, David W., Boukouvala, Sotiriab, Grant, Denis M., Minchin, Rodney F. and Sim, Edith (2008) Changes in consensus arylamine N-acetyltransferase gene nomenclature. Pharmacogenetics and Genomics, 18 4: 367-368. doi:10.1097/FPC.0b013e3282f60db0

E. coli nitroreductase/CB1954 gene-directed enzyme prodrug therapy: role of arylamine N-acetlytransferase 2

Mitchell, D. J. and Minchin, R. F. (2008) E. coli nitroreductase/CB1954 gene-directed enzyme prodrug therapy: role of arylamine N-acetlytransferase 2. Cancer Gene Therapy, 15 11: 758-764. doi:10.1038/cgt.2008.47

Nanomedicine: Sizing up targets with nanoparticles

Minchin, Rod (2008) Nanomedicine: Sizing up targets with nanoparticles. Nature Nanotechnology, 3 1: 12-13. doi:10.1038/nnano.2007.433

Sulfotransferase 4A1

Minchin, Rodney F., Lewis, Aaron, Mitchell, Deanne, Kadlubar, Fred F. and McManus, Michael E. (2008) Sulfotransferase 4A1. The International Journal of Biochemistry & Cell Biology, 40 12: 2686-2691. doi:10.1016/j.biocel.2007.11.010

The synthesis and characterisation of a novel dendritic system for gene delivery

Coles, Daniel J., Yang, Shu, Esposito, Anna, Mitchell, Deanne, Minchin, Rodney F. and Toth, Istvan (2007) The synthesis and characterisation of a novel dendritic system for gene delivery. Tetrahedron, 63 49: 12207-12214. doi:10.1016/j.tet.2007.09.048

Polyamine-dependent regulation of spermidine-spermine N-1-acetyltransferase mRNA translation

Butcher, Neville J., Broadhurst, Gysell M. and Minchin, Rodney F. (2007) Polyamine-dependent regulation of spermidine-spermine N-1-acetyltransferase mRNA translation. Journal of Biological Chemistry, 282 39: 28530-28539. doi:10.1074/jbc.M701265200

Arylamine N-acetyltransferase I

Minchin, RF, Hanna, PE, Dupret, JM, Wagner, CR, Rodrigues-Lima, F and Butcher, NJ (2007) Arylamine N-acetyltransferase I. International Journal of Biochemistry & Cell Biology, 39 11: 1999-2005. doi:10.1016/j.biocel.2006.12.006

Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells

Butcher, Neville J., Tetlow, Natasha L., Cheung, Catherine, Broadhurst, Gysell M. and Minchin, Rodney F. (2007) Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells. Cancer Research, 67 1: 85-92. doi:10.1158/0008-5472.CAN-06-2635

Modified Influenza Virosomes: Recent Advances and Potential in Gene Delivery

Khoshnejad, M., Young, P. R., Toth, I. and Minchin, R. F. (2007) Modified Influenza Virosomes: Recent Advances and Potential in Gene Delivery. Current Medicinal Chemistry, 14 29: 3152-3156. doi:10.2174/092986707782793989

Concentration dependent effects of N1,N11-diethylnorspermine on melanoma cell proliferation

Minchin, Rodney F., Knight, Samuel, Arulpragasam, Ajanthy and Fogel-Petrovic, Mirjana (2006) Concentration dependent effects of N1,N11-diethylnorspermine on melanoma cell proliferation. International Journal of Cancer, 118 2: 509-512. doi:10.1002/ijc.21359

Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities

Butcher, N. J., Arulpragasam, A., Goh, H. L., Davey, Tamara and Minchin, Rodney F. (2005) Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities. Biochemical Journal, 387 1: 119-127. doi:10.1042/BJ20040903

HIV LTR-dependent expression of Bax selectively induces apoptosis in Tat-positive cells

McCoubrie, J. E., Kendrick, T. S. and Minchin, R. F. (2004) HIV LTR-dependent expression of Bax selectively induces apoptosis in Tat-positive cells. Biochemical and Biophysical Research Communications, 325 4: 1459-1464. doi:10.1016/j.bbrc.2004.10.195

Interaction of the Hsp90 cochaperone cyclophilin 40 with Hsc70

Carrello, A, Allan, RK, Morgan, SL, Owen, BAL, Mok, D, Ward, BK, Minchin, RF, Toft, DO and Ratajczak, T (2004) Interaction of the Hsp90 cochaperone cyclophilin 40 with Hsc70. Cell Stress & Chaperones, 9 2: 167-181. doi:10.1379/CSC-26R.1

Mutational analysis of the large periplasmic loop 7-8 of the putrescine transporter PotE in Escherichia coli

Minchin, R. F. and McCoubrie, J. E. (2004) Mutational analysis of the large periplasmic loop 7-8 of the putrescine transporter PotE in Escherichia coli. International Journal of Biochemistry & Cell Biology, 36 2: 271-280. doi:10.1016/S1357-2725(03)00245-0

Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine - A mechanism for the slow acetylator phenotype and substrate-dependent down-regulation

Butcher, Neville J., Arulpragasam, Ajanthy and Minchin, Rodney F. (2004) Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine - A mechanism for the slow acetylator phenotype and substrate-dependent down-regulation. Journal of Biological Chemistry, 279 21: 22131-22137. doi:10.1074/jbc.M312858200

Immunophilin chaperones in steroid receptor signalling

Ratajczak, T., Ward, B. K. and Minchin, R. F. (2003) Immunophilin chaperones in steroid receptor signalling. Current Topics in Medicinal Chemistry, 3 12: 1348-1357. doi:10.2174/1568026033451934

Identification of a minimal promoter sequence for the human N-acetyltransferase Type I gene that binds AP-1 (activator protein 1) and YY-1 (Yin and Yang 1)

Butcher, NJ, Arulpragasam, A, Pope, C and Minchin, RF (2003) Identification of a minimal promoter sequence for the human N-acetyltransferase Type I gene that binds AP-1 (activator protein 1) and YY-1 (Yin and Yang 1). Biochemical Journal, 376 441-448. doi:10.1042/BJ20030650

ATP-dependent kinase-catalyzed activation of N-hydroxy hetero-cyclic amines

Kadlubar, FF, Minchin, RF, Teitel, CH, Turesky, RJ and Ilett, KF (2002) ATP-dependent kinase-catalyzed activation of N-hydroxy hetero-cyclic amines. Drug Metabolism Reviews, 34 27-27.

Pharmacogenetics of the arylamine N-acetyltransferases

Butcher, N. J., Boukouvala, S., Sim, E. and Minchin, R. F. (2002) Pharmacogenetics of the arylamine N-acetyltransferases. Pharmacogenomics Journal, 2 1: 30-42.

Allele and genotype frequencies of polymorphic cytochromes P4502D6, 2C19 and 2E1 in Aborigines from Western Australia

Griese, Ernst-Ulricha, Ilett, Kenneth F., Kitteringham, Neil R., Eichelbaum, Michela, Powell, Helend, Spargo, Randolph M., LeSouef, Peter N., Musk, A. William and Minchin, Rodney F. (2001) Allele and genotype frequencies of polymorphic cytochromes P4502D6, 2C19 and 2E1 in Aborigines from Western Australia. Pharmacogenetics, 11 1: 69-76. doi:10.1097/00008571-200102000-00008

Allelic loss of cyclophilin 40, an estrogen receptor-associated immunophilin, in breast carcinomas

Ward, BK, Kumar, P, Turbett, GR, Edmondston, JE, Papadimitriou, JM, Laing, NG, Ingram, DM, Minchin, RF and Ratajczak, T (2001) Allelic loss of cyclophilin 40, an estrogen receptor-associated immunophilin, in breast carcinomas. Journal of Cancer Research And Clinical Oncology, 127 2: 109-115. doi:10.1007/s004320000182

Estradiol-regulated expression of the immunophilins cyclophilin 40 and FKBP52 in MCF-7 breast cancer cells

Kumar, P, Mark, PJ, Ward, BK, Minchin, RF and Ratajczak, T (2001) Estradiol-regulated expression of the immunophilins cyclophilin 40 and FKBP52 in MCF-7 breast cancer cells. Biochemical And Biophysical Research Communications, 284 1: 219-225. doi:10.1006/bbrc.2001.4952

Human cyclophilin 40 is a heat shock protein that exhibits altered intracellular localization following heat shock

Mark, PJ, Ward, BK, Kumar, P, Lahooti, H, Minchin, RF and Ratajczak, T (2001) Human cyclophilin 40 is a heat shock protein that exhibits altered intracellular localization following heat shock. Cell Stress & Chaperones, 6 1: 59-70. doi:10.1379/1466-1268(2001)006<0059:HCIAHS>2.0.CO;2

Polyinosinic acid and polycationic liposomes attenuate the hepatic clearance of circulating plasmid DNA

Minchin, RF, Carpenter, D and Orr, RJ (2001) Polyinosinic acid and polycationic liposomes attenuate the hepatic clearance of circulating plasmid DNA. Journal of Pharmacology And Experimental Therapeutics, 296 3: 1006-1012.

Regulation of the Hsp90-binding immunophilin, cyclophilin 40, is mediated by multiple sites for CA-binding protein (GABP)

Kumar, P, Ward, BK, Minchin, RF and Ratajczak, T (2001) Regulation of the Hsp90-binding immunophilin, cyclophilin 40, is mediated by multiple sites for CA-binding protein (GABP). Cell Stress & Chaperones, 6 1: 78-91. doi:10.1379/1466-1268(2001)006<0078:ROTHBI>2.0.CO;2

Two structures of cyclophilin 40: Folding and fidelity in the TPR domains

Taylor, Paul, Dornan, Jacqueline, Carrello, Amerigo, Minchin, Rodney F., Ratajczak, Thomas and Walkinshaw, Malcolm D. (2001) Two structures of cyclophilin 40: Folding and fidelity in the TPR domains. Structure, 9 5: 431-438. doi:10.1016/S0969-2126(01)00603-7

An update on genetic, structural and functional studies of arylamine N-acetyltransferases in eucaryotes and procaryotes

Sim, E, Payton, M, Noble, M and Minchin, R (2000) An update on genetic, structural and functional studies of arylamine N-acetyltransferases in eucaryotes and procaryotes. Human Molecular Genetics, 9 16: 2435-2441. doi:10.1093/hmg/9.16.2435

Characterization of an ATP-dependent pathway of activation for the heterocyclic amine carcinogen N-hydroxy-2-amino-3-methylimidazo[4,5-f]quinoline

Agus, C, Ilett, KF, Kadlubar, FF and Minchin, RF (2000) Characterization of an ATP-dependent pathway of activation for the heterocyclic amine carcinogen N-hydroxy-2-amino-3-methylimidazo[4,5-f]quinoline. Carcinogenesis, 21 6: 1213-1219. doi:10.1093/carcin/21.6.1213

Genetic polymorphisms in glutathione S-transferase M1 and T1 in an Australian Aborigine population

Ilett, KF, McCormick, N, Carpenter, DS, Spargo, RM, Le Souef, PN, Musk, AW and Minchin, RF (2000) Genetic polymorphisms in glutathione S-transferase M1 and T1 in an Australian Aborigine population. Pharmacogenetics, 10 5: 477-480. doi:10.1097/00008571-200007000-00011

Inactivation of human arylamine N-acetyltransferase 1 by the hydroxylamine of p-aminobenzoic acid

Butcher, NJ, Ilett, KF and Minchin, RF (2000) Inactivation of human arylamine N-acetyltransferase 1 by the hydroxylamine of p-aminobenzoic acid. Biochemical Pharmacology, 60 12: 1829-1836. doi:10.1016/S0006-2952(00)00501-3

Substrate-dependent regulation of human arylamine N-acetyltransferase-1 in cultured cells

Butcher, NJ, Ilett, KF and Minchin, RF (2000) Substrate-dependent regulation of human arylamine N-acetyltransferase-1 in cultured cells. Molecular Pharmacology, 57 3: 468-473.

The pharmacology of gene therapy

Minchin, Rodney F., Orr, Rebecca J., Cronin, Andrew S. and Puls, Rebecca L. (1999) The pharmacology of gene therapy. Croatian Medical Journal, 40 3: 381-391.

Expression of the estrogen receptor-associated immunophilins, cyclophilin 40 and FKBP52, in breast cancer

Ward, BK, Mark, PJ, Ingram, DM, Minchin, RF and Ratajczak, T (1999) Expression of the estrogen receptor-associated immunophilins, cyclophilin 40 and FKBP52, in breast cancer. Breast Cancer Research And Treatment, 58 3: 267-280.

Gene transfer and expression of a non-viral polycation-based vector in CD4(+) cells

Puls, R. L. and Minchin, R. F. (1999) Gene transfer and expression of a non-viral polycation-based vector in CD4(+) cells. Gene Therapy, 6 10: 1774-1778. doi:10.1038/sj.gt.3301022

Purification,characterization and crystallization in two crystal forms of bovine cyclophilin 40

Dornan, A, Taylor, P, Carrello, A, Minchin, RF, Ratajczak, T and Walkinshaw, MD (1999) Purification,characterization and crystallization in two crystal forms of bovine cyclophilin 40. Acta Crystallographica Section D: Biological Crystallography, 55 5: 1079-1082. doi:10.1107/S0907444999003017

The common tetratricopeptide repeat acceptor site for steroid receptor-associated immunophilins and Hop is located in the dimerization domain of hsp90

Carrello, A, Ingley, E, Minchin, RF, Tsai, S and Ratajczak, T (1999) The common tetratricopeptide repeat acceptor site for steroid receptor-associated immunophilins and Hop is located in the dimerization domain of hsp90. Journal of Biological Chemistry, 274 5: 2682-2689. doi:10.1074/jbc.274.5.2682

Functional polymorphism of the human arylamine N-acetyltransferase type 1 gene caused by (CT)-T-190 and G(560)A mutations

Butcher, NJ, Ilett, KF and Minchin, RF (1998) Functional polymorphism of the human arylamine N-acetyltransferase type 1 gene caused by (CT)-T-190 and G(560)A mutations. Pharmacogenetics, 8 1: 67-72. doi:10.1097/00008571-199802000-00009

Targeting of a cholecystokinin-DNA complex to pancreatic cells in vitro and in vivo

Carpenter, D. S. and Minchin, R. F. (1998) Targeting of a cholecystokinin-DNA complex to pancreatic cells in vitro and in vivo. Gene Therapy, 5 6: 848-854. doi:10.1038/sj.gt.3300657

Cross-linking studies and membrane localization and assembly of radiolabelled large mechanosensitive ion channel (MscL) of Escherichia coli

Hase, CC, Minchin, RF, Kloda, A and Martinac, B (1997) Cross-linking studies and membrane localization and assembly of radiolabelled large mechanosensitive ion channel (MscL) of Escherichia coli. Biochemical And Biophysical Research Communications, 232 3: 777-782. doi:10.1006/bbrc.1997.6370

Cyclophilin 40 (PPID) gene - Map position 4q31.3

Ratajczak, T, Woollatt, E, Kumar, P, Ward, BK, Minchin, RF and Baker, E (1997) Cyclophilin 40 (PPID) gene - Map position 4q31.3. Chromosome Research, 5 2: 151-151.

Estimate of the pore size of the large mechanosensitive ion channel (MscL) of Escherichia coli.

Cruickshank, C, Minchin, RF, LeDain, AC and Martinac, B (1997) Estimate of the pore size of the large mechanosensitive ion channel (MscL) of Escherichia coli.. Biophysical Journal, 72 2: MPO63-MPO63.

Estimation of the pore size of the large-conductance mechanosensitive ion channel of Escherichia coli

Cruickshank, CC, Minchin, RF, LeDain, AC and Martinac, B (1997) Estimation of the pore size of the large-conductance mechanosensitive ion channel of Escherichia coli. Biophysical Journal, 73 4: 1925-1931.

Extracellular calcium stimulates Na+-dependent putrescine uptake in B16 melanoma cells

Minchin, RF and Martin, RL (1997) Extracellular calcium stimulates Na+-dependent putrescine uptake in B16 melanoma cells. International Journal of Biochemistry & Cell Biology, 29 3: 447-454. doi:10.1016/S1357-2725(96)00145-8

Metabolic activation of aromatic amines by human pancreas

Anderson, KE, Hammons, GJ, Kadlubar, FF, Potter, JD, Kaderlik, KR, Ilett, KF, Minchin, RF, Teitel, CH, Chou, HC, Martin, MV, Guengerich, FP, Barone, GW, Lang, NP and Peterson, LA (1997) Metabolic activation of aromatic amines by human pancreas. Carcinogenesis, 18 5: 1085-1092. doi:10.1093/carcin/18.5.1085

Uptake of the food-derived heterocyclic amine carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and its N-hydroxy metabolite into rat pancreatic acini and hepatocytes in vitro

Butcher, N.J., Minchin, R.F., Kadlubar, F.F. and llett , K.F. (1996) Uptake of the food-derived heterocyclic amine carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and its N-hydroxy metabolite into rat pancreatic acini and hepatocytes in vitro. Carcinogenesis, 17 4: 889-992. doi:10.1093/carcin/17.4.889

Binding and internalization of the melanocyte stimulating hormone receptor ligand [Nle(4), D-Phe(7)]alpha-MSH in B16 melanoma cells

Wong, WS and Minchin, RF (1996) Binding and internalization of the melanocyte stimulating hormone receptor ligand [Nle(4), D-Phe(7)]alpha-MSH in B16 melanoma cells. International Journal of Biochemistry & Cell Biology, 28 11: 1223-1232. doi:10.1016/S1357-2725(96)00074-X

Localization of Spermidine Uptake in Rabbit Lung Slices

Saunders, NA, McGeachie, JK, Ilett, KF and Minchin, RF (1989) Localization of Spermidine Uptake in Rabbit Lung Slices. American Journal of Physiology, 257 3: C579-C587.

Pulmonary Alveolar Macrophages Express a Polyamine Transport-System

Saunders, NA, Ilett, KF and Minchin, RF (1989) Pulmonary Alveolar Macrophages Express a Polyamine Transport-System. Journal of Cellular Physiology, 139 3: 624-631. doi:10.1002/jcp.1041390324

Autoradiographic Localization of Putrescine Uptake to Type-Ii Pneumocytes of Rabbit Lung Slices

Saunders, NA, Rigby, PJ, Ilett, KF and Minchin, RF (1988) Autoradiographic Localization of Putrescine Uptake to Type-Ii Pneumocytes of Rabbit Lung Slices. Laboratory Investigation, 59 3: 380-386.

Uptake, efflux and metabolism of the polyamine putrescine in rabbit lung slices

Saunders, NA, Ilett, KF and Minchin, RF (1987) Uptake, efflux and metabolism of the polyamine putrescine in rabbit lung slices. BBA - Molecular Cell Research, 927 2: 170-176. doi:10.1016/0167-4889(87)90131-5

Targeting the Arylamine N-Acetyltransferases in Cancer

Minchin, Rodney F. and Butcher, Neville J. (2014). Targeting the Arylamine N-Acetyltransferases in Cancer. In: Abstracts from the 10th International ISSX Meeting. 10th International Meeting of the International Society for the Study of Xenobiotics (ISSX), Toronto, Canada, (2-2). 29 September - 03 October 2013.

An automatic image based single dilution method for end point titre quantitation of antinuclear antibodies tests using HEp-2 cells

Wiliem, Arnold, Hobson, Peter, Minchin, Rodney F. and Lovell, Brian C. (2011). An automatic image based single dilution method for end point titre quantitation of antinuclear antibodies tests using HEp-2 cells. In: Proceedings of the 2011 International Conference on Digital Image Computing: Techniques and Applications. 2011 International Conference on Digital Image Computing: Techniques and Applications (DICTA 2011), Noosa, QLD, Australia, (1-6). 6 - 8 December 2011. doi:10.1109/DICTA.2011.9

Radiolabeled clay nanoparticles for toxicological investigations

Musumeci, Anthony, Broadhurst, Gysell, Smith, Suzanne, Xu, Zhi P., Minchin, Rodney F. and Martin, Darren J. (2009). Radiolabeled clay nanoparticles for toxicological investigations. In: Proceedings of the 8th World Biomaterials Congress. 8th World Biomaterials Conference, Amsterdam, The Netherlands, (). 28 May 2008 - 1 June, 2008.

The Characterisation of Novel Dendritic Carriers with DNA by Isothermal Titration Calorimetry

Coles, D., Yang, S., Esposito, A., Mitchell, D., Minchin, R. and Toth, I. (2007). The Characterisation of Novel Dendritic Carriers with DNA by Isothermal Titration Calorimetry. In: Wilce, J., Proceedings of the 4th International Peptide Symposium in conjunction with the 7th Australian Peptide Conference and the 2nd Asia-Pacific International Peptide Symposium, 2007. 4th International Peptide Symposium, Cairns, (). 21-25 October 2007.

Modified influenza virosomes for gene delivery

Khoshnejad, M., Toth, I., Young, P. R. and Minchin, R. F. (2006). Modified influenza virosomes for gene delivery. In: Brisbane Biological & Organic Chemistry Symposium. Brisbane Biological & Organic Chemistry Symposium, Brisbane, Qld, (Abstract). 24 Nov 2006.

The synthesis of a novel dendritic system for gene delivery

Coles, D. J., Yang, S., Esposito, A., Mitchell, D. J., Minchin, R. F. and Toth, I. (2006). The synthesis of a novel dendritic system for gene delivery. In: Proceedings of: Annual Conference of the Australasian Pharmaceutical Science Association. Annual Conference of the Australasian Pharmaceutical Science Association, Adelaide, Australia, (). 3-5 December, 2006.

The synthesis of a novel dendritic system for gene delivery

Coles, D. J., Yang, S, Esposito, A., Mitchell, D J, Minchin, R F and Toth, I (2006). The synthesis of a novel dendritic system for gene delivery. In: Brisbane Biological & Organic Chemistry Symposium. Brisbane Biological & Organic Chemistry Symposium, Brisbane, (Abstract). 24 November 2006.

Uptake of a multi-component non-viral gene delivery system and gene expression in mammalian cells

Yang, S, Coles, D. J., Esposito, A., Mitchell, D J, Toth, I and Minchin, R F (2006). Uptake of a multi-component non-viral gene delivery system and gene expression in mammalian cells. In: Annual Conference of the Australasian Pharmaceutical Science Assn. Annual Conference of the Australasian Pharmaceutical Science n, Adelaide, (Poster). 3-5 December, 2006.

Arylamine N-acetyltransferase - from xenobiotic metabolising enzyme to regulation of transcription

Minchin, Ron (2004). Arylamine N-acetyltransferase - from xenobiotic metabolising enzyme to regulation of transcription. In: C. J. Waterfield, Proceedings of the British Toxicology Society Annual Congress. The British Toxicology Society Annual Congress 2003, Nottingham, UK, (33-33). 1st - 4th September, 2003. doi:10.1016/j.tox.2004.06.030

The chromatin remodeller ATRX is a thyroid hormone responsive gene with a potential role as a repressor of erythropoiesis

Kendrick, T., Mus, A. M., Minchin, R., Leedman, P. and Klinken, P. (2004). The chromatin remodeller ATRX is a thyroid hormone responsive gene with a potential role as a repressor of erythropoiesis. In: Faseb: Annual Meeting of the American Society for Biochemistry and Molecular Biology/8th Congress of the International Union for Biochemistry and Molecular Biology. Annual Meeting of the American Society for Biochemistry and Molecular Biology/8th Congress of the International Union for Biochemistry and Molecular Biology, Boston, MA, (C195-C196). 12-16 Jun 2004.