Dr Xiaowen Liang

Research Fellow

Greenslopes Clinical Unit
Faculty of Medicine

UQ Development Fellow

Frazer Institute
Faculty of Medicine
+61 7 344 37487


My research focuses on liver biology and pharmacology and I am a research team leader of the joint liver cancer research program of Frazer Institute and Gallipoli Medical Research Foundation from 2019. My long-term goal is to direct a research group exploring strategies to improve liver cancer outcomes in patients, working closely with clinicians to enable bench-to-bedside translation.

Research Impacts

I developed an intravital imaging platform for visualising and characterising the spatial distribution of activated hepatic stellate cells and metabolic status in liver cancer. This imaging platform and physiologically based kinetics modelling was applied for the first time to investigate the sub-organ disposition and clearance of therapeutic agents in the liver. By expanding the initial work, I further led studies on assessment and monitoring of cellular oxidative stress, microcirculation, and drug response in the specific liver microenvironment for early prediction of treatment efficacy in liver diseases.


  • Doctor of Philosophy, The University of Queensland


View all Publications


View all Grants


View all Supervision



  • Benson, Heather A. E., Roberts, Michael S., Williams, Adrian C. and Liang, Xiaowen eds. (2021). Fundamentals of Drug Delivery. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/9781119769644

Book Chapter

  • Wang, Haolu, Yang, Haotian, Ruan, Qi, Roberts, Michael S. and Liang, Xiaowen (2022). Theranostic nanoparticles for imaging and targeted drug delivery to the liver. Fundamentals of drug delivery. (pp. 311-328) edited by Heather A. E. Benson, Michael S. Roberts, Adrian C. Williams and Xiaowen Liang. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781119769644.ch12

  • Holmes, Amy, Thorling, Camilla, Liu, Xin, Liang, Xiaowen, Wang, Haolu, Breunig, Hans G., König, Karsten, Studier, Hauke and Roberts, Michael S. (2018). Revealing interaction of dyes and nanomaterials by multiphoton imaging. Multiphoton microscopy and fluorescence lifetime imaging: applications in biology and medicine. (pp. 345-368) edited by Karsten König. Berlin, Germany: Walter de Gruyter. doi: 10.1515/9783110429985-020

  • Liu, X., Wang, H., Liang, X. and Roberts, M. S. (2017). Hepatic metabolism in liver health and disease. Liver Pathophysiology: Therapies and Antioxidants. (pp. 391-400) edited by Pablo Muriel. Cambridge, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-804274-8.00030-8

  • Liang, Xiaowen, Wang, Haolu, Liu, Xin, Grice, Jeffrey, Xu, Zhi Ping and Roberts, Michael S. (2017). Related topic: Safety evaluation of nanomaterials. Skin permeation and disposition of therapeutic and cosmeceutical compounds. (pp. 313-322) edited by Kenji Sugibayashi. Tokyo, Japan: Springer Japan. doi: 10.1007/978-4-431-56526-0_28

  • Thorling, Camilla A., Holmes, Amy, Studier, Hauke, Liu, David, Liang, Xiaowen and Roberts, Michael S. (2016). Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver. Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver. (pp. 107-123) edited by Stefan G. Stanciu. Rijeka, Croatia: InTech. doi: 10.5772/63452

Journal Article

Conference Publication

Other Outputs

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision