Dr Parker's fundamental research interest is the improved healthcare of infants and children through evidence-based drug dosing. Dr Parker is a bioanalyst with 20 years of experience designing methods to measure drugs in biological fluids, positioning her to develop kinder, less-invasive sampling methods that can improve the feasibility of clinical dosing studies. Dr Parker’s research career has furthered these laboratory skills into a translational framework: by applying innovation in microsampling her research will define evidence-based antibiotic dosing regimens.
To advance her research program, in 2016 Dr Parker established the Clinical Microsampling Group. Her research and experience is cross-disciplinary - based in infectious diseases, pharmacokinetic modelling and bioanalysis
Dr Parker has a series of important publications culminating in the characterization of fosfomycin, an antibiotic vital for the treatment of multi-drug resistant pathogens. This provided crucial evidence for effective dosing of this antibiotic in critically ill patients and advanced change in clinical practice. Dr Parker’s research has also produced world-first evidence essential for the implementation of microsampling in a clinical environment. Dr Parker has developed population pharmacokinetic models for clinical collaborators to describe dosing of drugs in challenging patient groups.
Journal Article: Stability of nafamostat in intravenous infusion solutions, human whole blood and extracted plasma: implications for clinical effectiveness studies
Hernández-Mitre, María Patricia, Won, Hayoung, Wallis, Steven C, Parker, Suzanne L and Roberts, Jason A (2023). Stability of nafamostat in intravenous infusion solutions, human whole blood and extracted plasma: implications for clinical effectiveness studies. Bioanalysis. doi: 10.4155/bio-2023-0040
Journal Article: Evaluation of a closed loop-blood sampling system in intensive care: A pilot randomised controlled trial. The ENCLOSE trial
Keogh, Samantha, Dhanani, Jayesh, Levido, Annabel, Gracie, Chris, Ilushin, Vladislav, Palmer, Jennifer, Doubrovsky, Anna, Parker, Suzanne L., Pintara, Alexander, Huygens, Flavia and Coyer, Fiona (2023). Evaluation of a closed loop-blood sampling system in intensive care: A pilot randomised controlled trial. The ENCLOSE trial. Intensive and Critical Care Nursing, 75 103364, 1-8. doi: 10.1016/j.iccn.2022.103364
Journal Article: Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients
Adiraju, Santosh K. S., Sumi, Chandra D., Pandey, Saurabh, Cotta, Menino O., Roberts, Jason A, Lipman, Jeffrey, Wallis, Steven C. and Parker, Suzanne L. (2023). Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients. Bioanalysis, 15 (1), 31-42. doi: 10.4155/bio-2022-0230
Pharmacogenomics for better treatment of fungal infections in cancer
(2023–2026) MRFF - National Critical Infrastructure Initiative
(2021–2026) NHMRC Centres of Research Excellence
Pharmacokinetics of antimicrobials in paediatric patients on extracorporeal therapies (APET-PK)
(2021–2025) Children's Health Queensland Hospital and Health Service
Translating Microsampling Techniques into Improved Antimicrobial Dosing for Critically Ill Children
(2023) Doctor Philosophy
How to use antibiotics better in Paediatric Intensive Care using pharmacokinetic principles
Doctor Philosophy
Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)
Doctor Philosophy
Hernández-Mitre, María Patricia, Won, Hayoung, Wallis, Steven C, Parker, Suzanne L and Roberts, Jason A (2023). Stability of nafamostat in intravenous infusion solutions, human whole blood and extracted plasma: implications for clinical effectiveness studies. Bioanalysis. doi: 10.4155/bio-2023-0040
Keogh, Samantha, Dhanani, Jayesh, Levido, Annabel, Gracie, Chris, Ilushin, Vladislav, Palmer, Jennifer, Doubrovsky, Anna, Parker, Suzanne L., Pintara, Alexander, Huygens, Flavia and Coyer, Fiona (2023). Evaluation of a closed loop-blood sampling system in intensive care: A pilot randomised controlled trial. The ENCLOSE trial. Intensive and Critical Care Nursing, 75 103364, 1-8. doi: 10.1016/j.iccn.2022.103364
Adiraju, Santosh K. S., Sumi, Chandra D., Pandey, Saurabh, Cotta, Menino O., Roberts, Jason A, Lipman, Jeffrey, Wallis, Steven C. and Parker, Suzanne L. (2023). Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients. Bioanalysis, 15 (1), 31-42. doi: 10.4155/bio-2022-0230
Setiawan, Eko, Cotta, Menino Osbert, Abdul-Aziz, Mohd-Hafiz, Widjanarko, Doddy, Sosilya, Hernycane, Lukas, Dwi Lily, Wallis, Steven C., Parker, Suzanne and Roberts, Jason A. (2023). Population pharmacokinetics and dosing simulations of ampicillin and sulbactam in hospitalised adult patients. Clinical Pharmacokinetics, 62 (4), 1-14. doi: 10.1007/s40262-023-01219-5
Scuderi, Carla, Parker, Suzanne, Jacks, Margaret, John, George T., McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Healy, Helen, Roberts, Jason and Staatz, Christine (2023). Fingerprick microsampling methods can replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid, and prednisolone concentrations in adult kidney transplant patients. Therapeutic Drug Monitoring, 45 (1), 69-78. doi: 10.1097/FTD.0000000000001024
Scuderi, Carla E., Parker, Suzanne L., Jacks, Margaret, John, George T., McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew J., Healy, Helen G., Roberts, Jason A. and Staatz, Christine E. (2023). Serum Creatinine and Tacrolimus Assessment With VAMS Finger-Prick Microsampling: A Diagnostic Test Study. Kidney Medicine, 5 (4) 100610, 100610. doi: 10.1016/j.xkme.2023.100610
Kong, Fabian Y. S., Unemo, Magnus, Lim, Shueh H., Latch, Ngaire, Williamson, Deborah A., Roberts, Jason A., Wallis, Steven C., Parker, Suzanne L., Landersdorfer, Cornelia B., Yap, Tami, Fairley, Christopher K., Chow, Eric P F, Lewis, David A., Hammoud, Mohamed A. and Hocking, Jane S. (2022). Optimisation of treatments for oral Neisseria gonorrhoeae infection: Pharmacokinetics Study (STI-PK project) - study protocol for non-randomised clinical trial. BMJ open, 12 (11) e064782, 1-8. doi: 10.1136/bmjopen-2022-064782
Ryan, Rochelle L., Jackson, Dwane, Hopkins, George, Eley, Victoria, Christensen, Rebecca, Van Zundert, Andre A. J., Wallis, Steven C., Lipman, Jeffrey, Parker, Suzanne L. and Roberts, Jason A. (2022). Plasma and interstitial fluid pharmacokinetics of prophylactic cefazolin in elective bariatric surgery patients. Antimicrobial Agents and Chemotherapy, 66 (7), e0041922. doi: 10.1128/aac.00419-22
Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2022). Optimal dosing of cefotaxime and desacetylcefotaxime for critically ill paediatric patients. Can we use microsampling?. Journal of Antimicrobial Chemotherapy, 77 (8), 2227-2237. doi: 10.1093/jac/dkac168
Sanches, Cristina, Alves, Geisa C. S., Farkas, Andras, da Silva, Samuel Dutra, de Castro, Whocely Victor, Chequer, Farah Maria Drummond, Beraldi-Magalhães, Francisco, Magalhães, Igor Rafael dos Santos, Baldoni, André de Oliveira, Chatfield, Mark D., Lipman, Jeffrey, Roberts, Jason A. and Parker, Suzanne L. (2022). Population pharmacokinetic model of piperacillin in critically ill patients and describing interethnic variation using external validation. Antibiotics, 11 (4) 434, 434. doi: 10.3390/antibiotics11040434
Parker, Suzanne L., Irwin, Adam D., Hosking, Francine, August, Deanne, Schoenmaker, Brittany, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Davies, Mark W. (2022). Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study. International Journal of Antimicrobial Agents, 59 (2) 106513, 1-2. doi: 10.1016/j.ijantimicag.2021.106513
Evaluation of low-volume plasma sampling for the analysis of meropenem in clinical samples
Parker, Suzanne L., Wallis, Steven C., Fourie, Cheryl, Lassig-Smith, Melissa, Starr, Therese, Chikatamarla, Avinash, Dorofaeff, Tavey, Chatfield, Mark D., Lipman, Jeffrey and Roberts, Jason A. (2022). Evaluation of low-volume plasma sampling for the analysis of meropenem in clinical samples. Analytical and Bioanalytical Chemistry, 414 (6), 2155-2162. doi: 10.1007/s00216-021-03851-1
Perioperative cefazolin prophylaxis in pediatric cardiac surgery: a prospective, cohort study
Suna, Jessica, Moloney, Gregory, Marathe, Supreet P., Bierbach, Benjamin, Roberts, Jason A., Parker, Suzanne, Ungerer, Jacobus P.J., McWhinney, Brett, Dorofaeff, Tavey, Venugopal, Prem and Alphonso, Nelson (2022). Perioperative cefazolin prophylaxis in pediatric cardiac surgery: a prospective, cohort study. Annals of Thoracic Surgery, 114 (4), 1434-1440. doi: 10.1016/j.athoracsur.2022.02.047
Beraldi-Magalhaes, Francisco, Parker, Suzanne L., Sanches, Cristina, Sousa Garcia, Leandro, Souza Carvalho, Brenda Karoline, Fachi, Mariana Millan, de Liz, Marcus Vinicius, Pontarolo, Roberto, Lipman, Jeffrey, Cordeiro-Santos, Marcelo and Roberts, Jason A. (2021). Is dosing of ethambutol as part of a fixed-dose combination product optimal for mechanically ventilated ICU patients with tuberculosis? A population pharmacokinetic study. Antibiotics, 10 (12) 1559. doi: 10.3390/antibiotics10121559
Rowe, David J., Owens, Daniel R., Parker, Suzanne L., Faust, Saul N., Wilkinson, James S. and Mashanovich, Goran Z. (2021). The effect of haematocrit on measurement of the mid-infrared refractive index of plasma in whole blood. Biosensors, 11 (11) 417. doi: 10.3390/bios11110417
Zylbersztajn, Brenda, Parker, Suzanne, Navea, Daniel, Izquierdo, Giannina, Ortiz, Paula, Torres, Juan Pablo, Fajardo, Cristian, Diaz, Rodrigo, Valverde, Cristian and Roberts, Jason (2021). Population pharmacokinetics of vancomycin and meropenem in pediatric extracorporeal membrane oxygenation support. Frontiers in Pharmacology, 12 709332, 1-10. doi: 10.3389/fphar.2021.709332
Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Roberts, Jason A., Lipman, Jeffrey, Coulthard, Mark G., Sparkes, Louise, Wallis, Steven C. and Parker, Suzanne L. (2021). Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children. Analytical and Bioanalytical Chemistry, 413 (17), 4483-4491. doi: 10.1007/s00216-021-03411-7
Microsampling to support pharmacokinetic clinical studies in pediatrics
Guerra Valero, Yarmarly, Dorofaeff, Tavey, Parker, Lisa, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2021). Microsampling to support pharmacokinetic clinical studies in pediatrics. Pediatric Research, 91 (6), 1-5. doi: 10.1038/s41390-021-01586-4
Population pharmacokinetics analysis of amikacin initial dosing regimen in elderly patients
Kato, Hideo, Parker, Suzanne L., Roberts, Jason A., Hagihara, Mao, Asai, Nobuhiro, Yamagishi, Yuka, Paterson, David L. and Mikamo, Hiroshige (2021). Population pharmacokinetics analysis of amikacin initial dosing regimen in elderly patients. Antibiotics, 10 (2) 100, 1-13. doi: 10.3390/antibiotics10020100
Sime, Fekade Bruck, Roberts, Jason A., Jeffree, Rosalind L., Pandey, Saurabh, Adiraju, Santosh, Livermore, Amelia, Butler, Jenie, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Cotta, Menino Osbert (2021). Population pharmacokinetics of levetiracetam in patients with traumatic brain injury and subarachnoid hemorrhage exhibiting augmented renal clearance. Clinical Pharmacokinetics, 60 (5), 655-664. doi: 10.1007/s40262-020-00979-8
Sime, Fekade B, Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Cerebrospinal fluid penetration of ceftolozane/tazobactam in critically ill patients with an indwelling external ventricular drain. Antimicrobial Agents and Chemotherapy, 65 (1) e01698-20, 1-11. doi: 10.1128/aac.01698-20
Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Stuart, Janine, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2020). A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies. Clinical Chemistry and Laboratory Medicine (CCLM), 59 (5), 921-933. doi: 10.1515/cclm-2020-1196
Hernandez-Mitre, Maria P., Medellin-Garibay, Susanna E., Rodríguez-Leyva, Ildefonso, Rodríguez-Pinal, Cristian J., Zarazúa, Sergio, Jung-Cook, Helgi H., Parker, Suzanne L., Romano-Moreno, Silvia and del C. Milán-Segovia, Rosa (2020). Determination of Levetiracetam in Plasma by a Modified HPLC-UV Method and Its Pharmacokinetic Application. Mathews Journal of Pharmaceutical Science, 4 (1). doi: 10.30654/mjps.10004
The role of antibiotic pharmacokinetic studies performed post-licensing
Parker, Suzanne L., Abdul-Aziz, Mohd Hafiz and Roberts, Jason A. (2020). The role of antibiotic pharmacokinetic studies performed post-licensing. International Journal of Antimicrobial Agents, 56 (6) 106165, 106165. doi: 10.1016/j.ijantimicag.2020.106165
Antithrombin dosing guidelines in children underestimate dose needed for plasma level increase
Mattke, Adrian C., Johnson, Kerry E., Parker, Suzanne, Stocker, Christian, Gibbons, Kristen and Schibler, Andreas (2020). Antithrombin dosing guidelines in children underestimate dose needed for plasma level increase. Pediatric Critical Care Medicine, 21 (8), 746-752. doi: 10.1097/PCC.0000000000002383
Kidney transplant recipient’s perceptions of blood testing through microsampling and venepuncture
Scuderi, Carla E., Parker, Suzanne L., Jacks, Margaret, John, George, McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Roberts, Jason A., Healy, Helen and Staatz, Christine E. (2020). Kidney transplant recipient’s perceptions of blood testing through microsampling and venepuncture. Bioanalysis, 12 (13) bio-2020-0057, 873-881. doi: 10.4155/bio-2020-0057
Eley, Victoria A., Christensen, Rebecca, Ryan, Rochelle, Jackson, Dwane, Parker, Suzanne L., Smith, Matthew, van Zundert, Andre A., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Prophylactic cefazolin dosing in women with body mass index >35 kg·m−2 undergoing cesarean delivery : a pharmacokinetic study of plasma and interstitial fluid. Anesthesia and Analgesia, 131 (1), 1-207. doi: 10.1213/ane.0000000000004766
Roberts, Jason A., Joynt, Gavin M., Lee, Anna, Choi, Gordon, Bellomo, Rinaldo, Kanji, Salmaan, Mudaliar, M Yugan, Peake, Sandra L., Stephens, Dianne, Taccone, Fabio Silvio, Ulldemolins, Marta, Valkonen, Miia Maaria, Agbeve, Julius, Baptista, João P., Bekos, Vasileios, Boidin, Clement, Brinkmann, Alexander, Buizen, Luke, Castro, Pedro, Cole, C. Louise, Creteur, Jacques, De Waele, Jan J., Deans, Renae, Eastwood, Glenn M., Escobar, Leslie, Gomersall, Charles, Gresham, Rebecca, Jamal, Janattul Ain, Kluge, Stefan ... Young, Helen (2020). The Effect of Renal Replacement Therapy and Antibiotic Dose on Antibiotic Concentrations in Critically Ill Patients: Data From the Multinational Sampling Antibiotics in Renal Replacement Therapy Study. Clinical Infectious Diseases, 72 (8), 1369-1378. doi: 10.1093/cid/ciaa224
Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration. Antimicrobial Agents and Chemotherapy, 64 (1) e01655. doi: 10.1128/aac.01655-19
Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2019). A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study. Analytical and Bioanalytical Chemistry, 411 (29), 7831-7840. doi: 10.1007/s00216-019-02184-4
Pandey, Saurabh, Dhanani, Jayesh, Lipman, Jeffrey, Roberts, Jason A., Wallis, Steve C. and Parker, Suzanne L. (2019). Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study. Clinical Chemistry and Laboratory Medicine, 58 (2), 274-284. doi: 10.1515/cclm-2019-0780
Gurunathan, Usha, Parker, Suzanne L., Maguire, Richard, Ramdath, Dale, Bijoor, Manu, Wallis, Steven C. and Roberts, Jason A. (2019). Population pharmacokinetics of periarticular ketorolac in adult patients undergoing total hip or total knee replacement surgery. Anesthesia and Analgesia, 129 (3), 701-708. doi: 10.1213/ANE.0000000000003377
Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2019). Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction. Antimicrobial Agents and Chemotherapy, 63 (10) e01265-19. doi: 10.1128/aac.01265-19
Sime, Fekade B., Byrn, Catherine J., Parker, Suzanne, Stuart, Janine, Butler, Jenie, Starr, Therese, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffery and Roberts, Jason A. (2019). Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients. Critical Care, 23 (1) 205, 205. doi: 10.1186/s13054-019-2483-9
Guerra Valero, Yarmarly C., Roberts, Jason A., Lipman, Jeffrey, Fourie, Cheryl, Starr, Therese, Wallis, Steven C. and Parker, Suzanne L. (2019). Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study. Journal of Pharmaceutical and Biomedical Analysis, 169, 288-292. doi: 10.1016/j.jpba.2019.03.018
Dhanani, Jayesh A., Diab, Sara, Chaudhary, Jivesh, Cohen, Jeremy, Parker, Suzanne L., Wallis, Steven C., Boidin, Clément, Barnett, Adrian, Chew, Michelle, Roberts, Jason A. and Fraser, John F. (2019). Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model. Anesthesiology, 131 (2), 1-355. doi: 10.1097/ALN.0000000000002752
Dimopoulos, George, Koulenti, Despoina, Parker, Suzanne L, Roberts, Jason A, Arvaniti, Kostoula and Poulakou, Garyphalia (2019). Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?. Expert Review of Anti-infective Therapy, 17 (3) 14787210.2019.1573669, 201-210. doi: 10.1080/14787210.2019.1573669
Sime, Fekade B., Pandey, Saurabh, Karamujic, Nermin, Parker, Suzanne, Alexander, Elizabeth, Loutit, Jeffery, Durso, Stephanie, Griffith, David, Lipman, Jeffrey, Wallis, Steven C. and Roberts, Jason A. (2018). Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam. Antimicrobial Agents and Chemotherapy, 62 (10) e01306, AAC.01306-18. doi: 10.1128/AAC.01306-18
Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F. and Roberts, Jason A. (2018). A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models. Intensive Care Medicine Experimental, 6 (1) 17, 17. doi: 10.1186/s40635-018-0180-7
Dhanani, Jayesh A., Parker, Suzanne L., Lipman, Jeffrey, Wallis, Steven C., Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle and Roberts, Jason A. (2018). Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions. Journal of Pharmaceutical Analysis, 8 (6), 407-412. doi: 10.1016/j.jpha.2018.07.003
Dhanani, Jayesh A., Tang, Patrician, Wallis, Steven C., Parker, Suzanne L., Pandey, Preeti, Fraser, John F., Cohen, Jeremy, Barnett, Adrian, Roberts, Jason R. and Chan, Hak-Kim (2018). Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation. Pulmonary Pharmacology and Therapeutics, 50, 93-99. doi: 10.1016/j.pupt.2018.04.006
Parker, Suzanne L, Saxena, Manoj, Gowardman, John, Lipman, Jeffrey, Myburgh, John and Roberts, Jason A. (2018). Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury. Journal of Critical Care, 47, 15-20. doi: 10.1016/j.jcrc.2018.05.016
Guerra Valero, Yarmarly C., Wallis, Steven C., Lipman, Jeffrey, Stove, Christophe, Roberts, Jason A. and Parker, Suzanne L. (2018). Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review. Bioanalysis, 10 (6), 407-423. doi: 10.4155/bio-2017-0269
Naicker, Saiyuri, Guerra Valero, Yarmarly C., Ordenez Meija, Jenny L., Lipman, Jeffrey, Roberts, Jason A., Wallis, Steven C. and Parker, Suzanne L. (2018). A UHPLC–MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent. Journal of Pharmaceutical and Biomedical Analysis, 148, 324-333. doi: 10.1016/j.jpba.2017.10.023
Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Weiss, Steven, Smith, Camilla, Russell, Lyndal, Smith, Paul, Roberts, Jason A and Wallis, Steven C (2017). A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples. Biomedical Chromatography, 31 (12) e4030, e4030. doi: 10.1002/bmc.4030
Parker, Suzanne L., Valero, Yarmarly C. Guerra, Mejia, Jenny L. Ordonez, Roger, Claire, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2017). An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent. Bioanalysis, 9 (12), 911-924. doi: 10.4155/bio-2017-0019
Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin
Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016). Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin. Bioanalysis, 8 (21), 2235-2242. doi: 10.4155/bio-2016-0159
Dorofaeff, Tavey, Bandini, Rossella M., Lipman, Jeffrey, Ballot, Daynia E., Roberts, Jason A. and Parker, Suzanne L. (2016). Uncertainty in antibiotic dosing in critically ill neonate and pediatric patients: can microsampling provide the answers?. Clinical Therapeutics, 38 (9), 1961-1975. doi: 10.1016/j.clinthera.2016.07.093
Parker, Suzanne L., Guerra Valero, Yarmarly C., Roberts, Darren M., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016). Determination of cefalothin and cefazolin in human plasma, urine and peritoneal dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Biomedical Chromatography, 30 (6), 872-879. doi: 10.1002/bmc.3622
Is there a role for microsampling in antibiotic pharmacokinetic studies?
Parker, Suzanne L., Dorofaeff, Tavey, Lipman, Jeffrey, Ballot, Daynia E., Bandini, Rossella M., Wallis, Steven C. and Roberts, Jason A. (2016). Is there a role for microsampling in antibiotic pharmacokinetic studies?. Expert Opinion on Drug Metabolism and Toxicology, 12 (6), 601-614. doi: 10.1080/17425255.2016.1178238
The use and risks of antibiotics in critically ill patients
Denny, Kerina J., Cotta, Menino O., Parker, Suzanne L., Roberts, Jason A. and Lipman, Jeffrey (2016). The use and risks of antibiotics in critically ill patients. Expert Opinion on Drug Safety, 15 (5), 667-678. doi: 10.1517/14740338.2016.1164690
Parker, Suzanne L., Lipman, Jeffrey, Dimopoulos, George, Roberts, Jason A. and Wallis, Steven C. (2015). A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 115, 509-514. doi: 10.1016/j.jpba.2015.07.013
Population pharmacokinetics of fosfomycin in critically ill patients
Parker, Suzanne L., Frantzeskaki, Frantzeska, Wallis, Steven C., Diakaki, Chryssa, Giamarellou, Helen, Koulenti, Despoina, Karaiskos, Ilias, Lipman, Jeffrey, Dimopoulos, George and Roberts, Jason A. (2015). Population pharmacokinetics of fosfomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (10), 6471-6476. doi: 10.1128/AAC.01321-15
Parker, Suzanne L., Roberts, Jason A., Lipman, Jeffrey and Wallis, Steven C. (2015). Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling. Bioanalysis, 7 (19), 2585-2595. doi: 10.4155/bio.15.173
Optimizing dosing of antibiotics in critically ill patients
Parker, Suzanne L., Sime, Fekade B. and Roberts, Jason A. (2015). Optimizing dosing of antibiotics in critically ill patients. Current Opinion in Infectious Diseases, 28 (6), 497-504. doi: 10.1097/QCO.0000000000000206
Parker, Suzanne L., Adnan, Syamhanin, Meija, Jenny L. Ordonez, Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2015). An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine. Bioanalysis, 7 (18), 2311-2319. doi: 10.4155/bio.15.143
Parker S.L., Lipman J., Roberts J.A. and Wallis S.C. (2015). A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 105, 39-45. doi: 10.1016/j.jpba.2014.11.042
Parker, Suzanne, Lipman, Jeffrey, Koulenti, Despoina, Dimopoulos, George and Roberts, Jason A. (2013). What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review. International Journal of Antimicrobial Agents, 42 (4), 289-293. doi: 10.1016/j.ijantimicag.2013.05.018
Steady-state dispositions of valproate and diflunisal alone and coadministered to healthy volunteers
Addison, RS, Parker-Scott, SL, Eadie, MJ, Hooper, WD and Dickinson, RG (2000). Steady-state dispositions of valproate and diflunisal alone and coadministered to healthy volunteers. European Journal of Clinical Pharmacology, 56 (9-10), 715-721. doi: 10.1007/s002280000211
Valproate metabolism during valproate-associated hepatotoxicity in a surviving adult patient
McLaughlin, DB, Eadie, MJ, Parker-Scott, SL, Addison, RS, Henderson, RD, Hooper, WD and Dickinson, RG (2000). Valproate metabolism during valproate-associated hepatotoxicity in a surviving adult patient. Epilepsy Research, 41 (3), 259-268. doi: 10.1016/S0920-1211(00)00151-0
Effect of naproxen co-administration on valproate disposition
Addison, RS, Parker-Scott, SL, Hooper, WD, Eadie, MJ and Dickinson, RG (2000). Effect of naproxen co-administration on valproate disposition. Biopharmaceutics & Drug Disposition, 21 (6), 235-242. doi: 10.1002/bdd.235
Rowe, David J., Owens, Daniel R., Nedeljkovic, Milos, Stirling, Callum J., Cathie, Katrina, Parker, Suzanne L., Faust, Saul N., Mashanovich, Goran Z. and Wilkinson, James S. (2023). Improving tuberculosis treatment using mid-infrared spectroscopy for bedside therapeutic drug monitoring. SPIE. doi: 10.1117/12.2649135
Scuderi, C. E., Parker, S. L., Jacks, M., John, G. T., McWhinney, B., Ungerer, J., Mallett, A. J., Healy, H. G., Roberts, J. A. and Staatz, C. E. (2022). Tacrolimus, mycophenolate and prednisolone concentration monitoring using microsampling instead of venepuncture in kidney transplant patients. Society of Hospital Pharmacists of Australia, Brisbane, QLD, Australia, 1-3 December 2022.
Scuderi, Carla, Parker, Suzanne, Jacks, Margaret, John, George, McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Healy, Helen, Roberts, Jason and Staatz, Christine (2022). Can microsampling methods replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid and prednisolone concentrations in adult kidney transplant patients?. 57th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, NSW Australia, 17-19 October 2022. Richmond, VIC Australia: John Wiley & Sons.
Scuderi, C., Parker, S., John, G., McWhinney, B., Ungerer, J., Mallett, A., Roberts, J., Healy, H. and Staatz, C. E. (2022). Is creatine and tacrolimus measurement through VAMS microsampling the future for adult kidney transplant patients? . Australian and New Zealand Society of Nephrology meeting, Sydney, NSW, Australia, October 2022.
Trimethoprim and sulphathiazole pharmacokinetic evaluation in adult kidney transplant recipients.
Scuderi, C., Jahan, S., Parker, S., Wallis, S., Jacks, M., John, G., McWhinney, B., Ungerer, J., Mallett. A., Healy, H., Roberts, J. and Staatz, C. (2022). Trimethoprim and sulphathiazole pharmacokinetic evaluation in adult kidney transplant recipients. . Society of Hospital Pharmacists of Australia conference, Adelaide, SA Australia, 24-26 February 2022. HOBOKEN: WILEY.
Keogh, Samantha, Dhanani, Jayesh, Levido, Annabel, Gracie, Chris, Ilushin, Vladislav, Palmer, Jennifer, Parker, Suzanne, Doubrovsky, Anna, Hyugens, Flavia and Coyer, Fiona (2022). Evaluation of a closed loop blood sampling system in intensive care: A pilot randomised controlled trial. The enclose trial. ANZICS/ACCCN intensive care annual scientific meeting, Sydney, NSW Australia, 27-29 April 2022. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2022.08.015
Trimethoprim-sulfamethoxazole pharmacokinetic evaluation in adult kidney transplant patients
Scuderi, C.E., Jahan, S., Parker, S. L., Jacks, M., John, G., McWhinney, B., Ungerer, J., Mallett, A., Healy, H., Roberts, J.A. and Staatz, C. E. (2021). Trimethoprim-sulfamethoxazole pharmacokinetic evaluation in adult kidney transplant patients. Australian and New Zealand Society of Nephrology conference, Virtual, September 2021.
Scuderi, C., Parker, S., John, G., McWhinney, B., Ungerer, J., Mallett, A., Roberts, J., Healy, H. and Staatz, C.E. (2020). Interest in possible alternative methods to venepuncture-based monitoring in kidney transplant patients. . RBWH Symposium, Brisbane, QLD Australia, 7-11 December 2020.
The burden of venepuncture for kidney transplant patients and interest in possible solutions.
Scuderi, C., Parker, S., John, G., McWhinney, B., Ungerer, J., Mallett, A., Roberts, J., Healy, H. and Staatz, C.E. (2020). The burden of venepuncture for kidney transplant patients and interest in possible solutions. . Society of Hospital Pharmacists of Australia, Online, 21-22 November 2020.
Collaborations with Junior Colleagues for Building Research Capacity in the Public Sector
Siskind, D., Kisely, S. and Parker, S. (2017). Collaborations with Junior Colleagues for Building Research Capacity in the Public Sector. LONDON: SAGE PUBLICATIONS LTD. doi: 10.1177/0004867417702054
How to do qualitative research?
Parker, S. (2017). How to do qualitative research?. RANZCP 2017 Congress, Adelaide, Australia, 30 April - 4 May 2017. London, United Kingdom: Sage Publication.
Aspects of time- and concentration-related of valproate in humans
Addison, R. S., Dickinson, R. G., Eadie, M., Hooper, W. D., Parker-Scott, S. L. and Reith, D. (2000). Aspects of time- and concentration-related of valproate in humans. Annual Scientifc Meeting of ASCEPT, Newcastle, Australia, 03-06 Dec, 2000. Melbourne, Australia: Aust. Society of Clin. & Exp. Pharmacologists & Toxicologists.
Effect of naproxen co-administration on valproate disposition
Addison, R. S., Dickinson, R. G., Hooper, W. D. and Parker-Scott, S. L. (2000). Effect of naproxen co-administration on valproate disposition. DMW/ISSX 2000 Meeting, St Andrews, Scotland, 11-16 Jun, 2000. New York: Marcel Dekker.
Interplay between b-oxidation and glucuronidation of valproate in humans
Addison, R. S., Dickinson, R. G., Hooper, W. D. and Parker-Scott, S. L. (2000). Interplay between b-oxidation and glucuronidation of valproate in humans. DMW/ISSX 2000 Meeting, St Andrews, Scotland, 11-16 Jun, 2000. New York: Dekker.
The renal handling of valproate and several metabolites in humans
Addison, R. S., Dickinson, R. G., Eadie, M., Hooper, W. D. and Parker-Scott, S. L. (2000). The renal handling of valproate and several metabolites in humans. Annual Scientific Meeting of ASCEPT, Newcastle, Australia, 03-06 Dec, 2000. Melbourne: Aust Society of Clin. & Exp. Pharmacologists & Toxicologists.
Effect of Naproxen co-administration on Valproate disposition
Addison, R. S., Dickinson, R. G., Hooper, W. D. and Parker-Scott, S. L. (1999). Effect of Naproxen co-administration on Valproate disposition. 33rd Annual Scientific Meeting of ASCEPT, Sydney Convention & Exhibition Cen., Darling Harbour, 4 - 8 Dec, 1999. Sydney: Australian Society of Clinical & Experimental Pharmacology & Toxicology.
Steady state dispositions of Valproate and Diflunisal alone and coadministered to healthy volunteers
Addison, R. S., Dickinson, R. G., Eadie, M. J., Hooper, W. D. and Parker-Scott, S. L. (1999). Steady state dispositions of Valproate and Diflunisal alone and coadministered to healthy volunteers. ASCEPT, Sydney Convention & Exhibition Cen., Darling Harbour, 4 - 8 Dec, 1999. Sydney: Aust. Soc. of Clinical & Experimental Pharm. & Toxicol..
Parker, Suzanne (2016). Translating innovative pharmacokinetic sampling techniques into improved antibiotic dosing regimens in critically ill patients. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2016.70
Pharmacogenomics for better treatment of fungal infections in cancer
(2023–2026) MRFF - National Critical Infrastructure Initiative
(2021–2026) NHMRC Centres of Research Excellence
Pharmacokinetics of antimicrobials in paediatric patients on extracorporeal therapies (APET-PK)
(2021–2025) Children's Health Queensland Hospital and Health Service
(2021–2022) Preclinical and Clinical Early Career Research
(2021–2022) Sunshine Coast Hospital and Health Service
(2020–2022) The Children's Hospital Foundation
(2019–2020) Metro North Hospital and Health Service
(2018–2021) The Children's Hospital Foundation
Translating a Drop of Blood into Effective Antibiotic Dosing in Infants and Children
(2018–2021) NHMRC Early Career Fellowships
(2018–2019) The Children's Hospital Foundation
(2018–2019) UQ Early Career Researcher
(2018–2019) Metro North Hospital and Health Service
(2017) Royal Brisbane and Women's Hospital Foundation
Using a drop of blood to personalise antibiotic dosing in children and prevent antibiotic resistance
(2016–2018) Ian Potter Foundation
How to use antibiotics better in Paediatric Intensive Care using pharmacokinetic principles
Doctor Philosophy — Principal Advisor
Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)
Doctor Philosophy — Principal Advisor
Other advisors:
Discovery and development of an Antibiotic Modulator to Break Antibiotic Resistance in a Mouse Infection Model
Doctor Philosophy — Associate Advisor
Stability of cephalosporin/b-lactam with b-lactamase inhibitor combinations for use in OPAT and simulation of OPAT-like drug exposures in a Biofilm model to assess the effect on MDR isolates.
Doctor Philosophy — Associate Advisor
Other advisors:
Translating Microsampling Techniques into Improved Antimicrobial Dosing for Critically Ill Children
(2023) Doctor Philosophy — Principal Advisor
Other advisors: