The University of Queensland

A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2019) A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study. Analytical and Bioanalytical Chemistry, . doi:10.1007/s00216-019-02184-4

Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study

Pandey, Saurabh, Dhanani, Jayesh, Lipman, Jeffrey, Roberts, Jason A., Wallis, Steve C. and Parker, Suzanne L. (2019) Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study. Clinical Chemistry and Laboratory Medicine, . doi:10.1515/cclm-2019-0780

A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2019) A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration. Antimicrobial Agents and Chemotherapy, . doi:10.1128/aac.01655-19

Population pharmacokinetics of periarticular ketorolac in adult patients undergoing total hip or total knee replacement surgery

Gurunathan, Usha, Parker, Suzanne L., Maguire, Richard, Ramdath, Dale, Bijoor, Manu, Wallis, Steven C. and Roberts, Jason A. (2019) Population pharmacokinetics of periarticular ketorolac in adult patients undergoing total hip or total knee replacement surgery. Anesthesia and Analgesia, 129 3: 701-708. doi:10.1213/ANE.0000000000003377

Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2019) Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction. Antimicrobial Agents and Chemotherapy, 63 10: . doi:10.1128/aac.01265-19

Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients

Sime, Fekade B., Byrn, Catherine J., Parker, Suzanne, Stuart, Janine, Butler, Jenie, Starr, Therese, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffery and Roberts, Jason A. (2019) Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients. Critical Care, . doi:10.1186/s13054-019-2483-9

Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study

Guerra Valero, Yarmarly C., Roberts, Jason A., Lipman, Jeffrey, Fourie, Cheryl, Starr, Therese, Wallis, Steven C. and Parker, Suzanne L. (2019) Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study. Journal of Pharmaceutical and Biomedical Analysis, 169 288-292. doi:10.1016/j.jpba.2019.03.018

Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model

Dhanani, Jayesh A., Diab, Sara, Chaudhary, Jivesh, Cohen, Jeremy, Parker, Suzanne L., Wallis, Steven C., Boidin, Clément, Barnett, Adrian, Chew, Michelle, Roberts, Jason A. and Fraser, John F. (2019) Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model. Anesthesiology, 131 2: 1-355. doi:10.1097/ALN.0000000000002752

Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?

Dimopoulos, George, Koulenti, Despoina, Parker, Suzanne L, Roberts, Jason A, Arvaniti, Kostoula and Poulakou, Garyphalia (2019) Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?. Expert Review of Anti-infective Therapy, 17 3: 201-210. doi:10.1080/14787210.2019.1573669

Ex vivo characterization of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam

Sime, Fekade B., Pandey, Saurabh, Karamujic, Nermin, Parker, Suzanne, Alexander, Elizabeth, Loutit, Jeffery, Durso, Stephanie, Griffith, David, Lipman, Jeffrey, Wallis, Steven C. and Roberts, Jason A. (2018) Ex vivo characterization of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam. Antimicrobial Agents and Chemotherapy, 62 10: . doi:10.1128/AAC.01306-18

Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam

Sime, Fekade B., Pandey, Saurabh, Karamujic, Nermin, Parker, Suzanne, Alexander, Elizabeth, Loutit, Jeffery, Durso, Stephanie, Griffith, David, Lipman, Jeffrey, Wallis, Steven C. and Roberts, Jason A. (2018) Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam. Antimicrobial Agents and Chemotherapy, 62 10: AAC.01306-18. doi:10.1128/AAC.01306-18

A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models

Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F. and Roberts, Jason A. (2018) A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models. Intensive Care Medicine Experimental, 6 1: 17. doi:10.1186/s40635-018-0180-7

Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions

Dhanani, Jayesh A., Parker, Suzanne L., Lipman, Jeffrey, Wallis, Steven C., Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle and Roberts, Jason A. (2018) Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions. Journal of Pharmaceutical Analysis, . doi:10.1016/j.jpha.2018.07.003

Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury

Parker, Suzanne L, Saxena, Manoj, Gowardman, John, Lipman, Jeffrey, Myburgh, John and Roberts, Jason A. (2018) Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury. Journal of Critical Care, 47 15-20. doi:10.1016/j.jcrc.2018.05.016

Population pharmacokinetics of periarticular ketorolac in adult patients undergoing total hip or total knee replacement surgery

Gurunathan, Usha, Parker, Suzanne L., Maguire, Richard, Ramdath, Dale, Bijoor, Manu, Wallis, Steven C. and Roberts, Jason A. (2018) Population pharmacokinetics of periarticular ketorolac in adult patients undergoing total hip or total knee replacement surgery. Anesthesia and Analgesia, 1. doi:10.1213/ANE.0000000000003377

Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation

Dhanani, Jayesh A., Tang, Patrician, Wallis, Steven C., Parker, Suzanne L., Pandey, Preeti, Fraser, John F., Cohen, Jeremy, Barnett, Adrian, Roberts, Jason R. and Chan, Hak-Kim (2018) Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation. Pulmonary Pharmacology and Therapeutics, 50 93-99. doi:10.1016/j.pupt.2018.04.006

Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review

Guerra Valero, Yarmarly C., Wallis, Steven C., Lipman, Jeffrey, Stove, Christophe, Roberts, Jason A. and Parker, Suzanne L. (2018) Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review. Bioanalysis, 10 6: 407-423. doi:10.4155/bio-2017-0269

A UHPLC–MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent

Naicker, Saiyuri, Guerra Valero, Yarmarly C., Ordenez Meija, Jenny L., Lipman, Jeffrey, Roberts, Jason A., Wallis, Steven C. and Parker, Suzanne L. (2018) A UHPLC–MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent. Journal of Pharmaceutical and Biomedical Analysis, 148 324-333. doi:10.1016/j.jpba.2017.10.023

A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples

Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Weiss, Steven, Smith, Camilla, Russell, Lyndal, Smith, Paul, Roberts, Jason A and Wallis, Steven C (2017) A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples. Biomedical Chromatography, 31 12: e4030. doi:10.1002/bmc.4030

An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent

Parker, Suzanne L., Valero, Yarmarly C. Guerra, Mejia, Jenny L. Ordonez, Roger, Claire, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2017) An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent. Bioanalysis, 9 12: 911-924. doi:10.4155/bio-2017-0019

Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin

Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016) Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin. Bioanalysis, 8 21: 2235-2242. doi:10.4155/bio-2016-0159

Uncertainty in antibiotic dosing in critically ill neonate and pediatric patients: can microsampling provide the answers?

Dorofaeff, Tavey, Bandini, Rossella M., Lipman, Jeffrey, Ballot, Daynia E., Roberts, Jason A. and Parker, Suzanne L. (2016) Uncertainty in antibiotic dosing in critically ill neonate and pediatric patients: can microsampling provide the answers?. Clinical Therapeutics, 38 9: 1961-1975. doi:10.1016/j.clinthera.2016.07.093

Determination of cefalothin and cefazolin in human plasma, urine and peritoneal dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans

Parker, Suzanne L., Guerra Valero, Yarmarly C., Roberts, Darren M., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016) Determination of cefalothin and cefazolin in human plasma, urine and peritoneal dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Biomedical Chromatography, 30 6: 872-879. doi:10.1002/bmc.3622

Is there a role for microsampling in antibiotic pharmacokinetic studies?

Parker, Suzanne L., Dorofaeff, Tavey, Lipman, Jeffrey, Ballot, Daynia E., Bandini, Rossella M., Wallis, Steven C. and Roberts, Jason A. (2016) Is there a role for microsampling in antibiotic pharmacokinetic studies?. Expert Opinion on Drug Metabolism and Toxicology, 12 6: 601-614. doi:10.1080/17425255.2016.1178238

The use and risks of antibiotics in critically ill patients

Denny, Kerina J., Cotta, Menino O., Parker, Suzanne L., Roberts, Jason A. and Lipman, Jeffrey (2016) The use and risks of antibiotics in critically ill patients. Expert Opinion on Drug Safety, 15 5: 667-678. doi:10.1517/14740338.2016.1164690

A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans

Parker, Suzanne L., Lipman, Jeffrey, Dimopoulos, George, Roberts, Jason A. and Wallis, Steven C. (2015) A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 115 509-514. doi:10.1016/j.jpba.2015.07.013

Population pharmacokinetics of fosfomycin in critically ill patients

Parker, Suzanne L., Frantzeskaki, Frantzeska, Wallis, Steven C., Diakaki, Chryssa, Giamarellou, Helen, Koulenti, Despoina, Karaiskos, Ilias, Lipman, Jeffrey, Dimopoulos, George and Roberts, Jason A. (2015) Population pharmacokinetics of fosfomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 10: 6471-6476. doi:10.1128/AAC.01321-15

Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling

Parker, Suzanne L., Roberts, Jason A., Lipman, Jeffrey and Wallis, Steven C. (2015) Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling. Bioanalysis, 7 19: 2585-2595. doi:10.4155/bio.15.173

Optimizing dosing of antibiotics in critically ill patients

Parker, Suzanne L., Sime, Fekade B. and Roberts, Jason A. (2015) Optimizing dosing of antibiotics in critically ill patients. Current Opinion in Infectious Diseases, 28 6: 497-504. doi:10.1097/QCO.0000000000000206

An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine

Parker, Suzanne L., Adnan, Syamhanin, Meija, Jenny L. Ordonez, Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2015) An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine. Bioanalysis, 7 18: 2311-2319. doi:10.4155/bio.15.143

A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans

Parker S.L., Lipman J., Roberts J.A. and Wallis S.C. (2015) A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 105 39-45. doi:10.1016/j.jpba.2014.11.042

What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review

Parker, Suzanne, Lipman, Jeffrey, Koulenti, Despoina, Dimopoulos, George and Roberts, Jason A. (2013) What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review. International Journal of Antimicrobial Agents, 42 4: 289-293. doi:10.1016/j.ijantimicag.2013.05.018

Steady-state dispositions of valproate and diflunisal alone and coadministered to healthy volunteers

Addison, RS, Parker-Scott, SL, Eadie, MJ, Hooper, WD and Dickinson, RG (2000) Steady-state dispositions of valproate and diflunisal alone and coadministered to healthy volunteers. European Journal of Clinical Pharmacology, 56 9-10: 715-721. doi:10.1007/s002280000211

Valproate metabolism during valproate-associated hepatotoxicity in a surviving adult patient

McLaughlin, DB, Eadie, MJ, Parker-Scott, SL, Addison, RS, Henderson, RD, Hooper, WD and Dickinson, RG (2000) Valproate metabolism during valproate-associated hepatotoxicity in a surviving adult patient. Epilepsy Research, 41 3: 259-268. doi:10.1016/S0920-1211(00)00151-0

Effect of naproxen co-administration on valproate disposition

Addison, RS, Parker-Scott, SL, Hooper, WD, Eadie, MJ and Dickinson, RG (2000) Effect of naproxen co-administration on valproate disposition. Biopharmaceutics & Drug Disposition, 21 6: 235-242. doi:10.1002/bdd.235

Collaborations with Junior Colleagues for Building Research Capacity in the Public Sector

Siskind, D., Kisely, S. and Parker, S. (2017). Collaborations with Junior Colleagues for Building Research Capacity in the Public Sector. In: Australian and New Zealand Journal of Psychiatry. , , (23-23). . doi:10.1177/0004867417702054

How to do qualitative research?

Parker, S. (2017). How to do qualitative research?. In: RANZCP 2017 Congress, Adelaide, Australia, (53-54). 30 April - 4 May 2017.

Aspects of time- and concentration-related of valproate in humans

Addison, R. S., Dickinson, R. G., Eadie, M., Hooper, W. D., Parker-Scott, S. L. and Reith, D. (2000). Aspects of time- and concentration-related of valproate in humans. In: Proceedings of ASCEPT. Annual Scientifc Meeting of ASCEPT, Newcastle, Australia, (121-121). 03-06 Dec, 2000.

Effect of naproxen co-administration on valproate disposition

Addison, R. S., Dickinson, R. G., Hooper, W. D. and Parker-Scott, S. L. (2000). Effect of naproxen co-administration on valproate disposition. In: Drug Metabolism Reviews. DMW/ISSX 2000 Meeting, St Andrews, Scotland, (29-29). 11-16 Jun, 2000.

Interplay between b-oxidation and glucuronidation of valproate in humans

Addison, R. S., Dickinson, R. G., Hooper, W. D. and Parker-Scott, S. L. (2000). Interplay between b-oxidation and glucuronidation of valproate in humans. In: Drug Metabolism Reviews. DMW/ISSX 2000 Meeting, St Andrews, Scotland, (62-62). 11-16 Jun, 2000.

The renal handling of valproate and several metabolites in humans

Addison, R. S., Dickinson, R. G., Eadie, M., Hooper, W. D. and Parker-Scott, S. L. (2000). The renal handling of valproate and several metabolites in humans. In: Proceedings of ASCEPT. Annual Scientific Meeting of ASCEPT, Newcastle, Australia, (121-121). 03-06 Dec, 2000.

Effect of Naproxen co-administration on Valproate disposition

Addison, R. S., Dickinson, R. G., Hooper, W. D. and Parker-Scott, S. L. (1999). Effect of Naproxen co-administration on Valproate disposition. In: Abstracts of the Scientific Meeting of ASCEPT. 33rd Annual Scientific Meeting of ASCEPT, Sydney Convention & Exhibition Cen., Darling Harbour, (136-136). 4 - 8 Dec, 1999.

Steady state dispositions of Valproate and Diflunisal alone and coadministered to healthy volunteers

Addison, R. S., Dickinson, R. G., Eadie, M. J., Hooper, W. D. and Parker-Scott, S. L. (1999). Steady state dispositions of Valproate and Diflunisal alone and coadministered to healthy volunteers. In: Proceedings of ASCEPT 33rd Annual Scienctific Meeting. ASCEPT, Sydney Convention & Exhibition Cen., Darling Harbour, (146). 4 - 8 Dec, 1999.

Translating innovative pharmacokinetic sampling techniques into improved antibiotic dosing regimens in critically ill patients

Parker, Suzanne (2016). Translating innovative pharmacokinetic sampling techniques into improved antibiotic dosing regimens in critically ill patients PhD Thesis, School of Medicine, The University of Queensland. doi:10.14264/uql.2016.70