Professor Goodhill's lab is interested in how brains process information, particularly during development. This includes how growing nerve fibres use molecular cues to make guidance decisions, how map-like representations of visual inputs form in the optic tectum and visual cortex, and how these maps code sensory information. He is addressing these questions using a combination of mathematical, experimental and computational techniques. Members of the lab come from diverse backgrounds including biology, mathematics, physics and computer science.
Prof Goodhill originally trained in Mathematics, Physics, Artificial Intelligence and Cognitive Science in the UK. He then spent 10 years in the USA, including 8 as Professor at Georgetown University in Washington DC, where he was awarded tenure 2 years early. He moved to the University of Queensland in 2005. He has published over 100 peer-reviewed papers including in Nature Neuroscience, 4 in Neuron, 4 in PNAS and 8 in Trends in Neurosciences. In 2014 he received the Paxinos-Watson prize from the Australasian Neuroscience Society for a paper in Neuron. Since moving to Australia he has been awarded an NHMRC Investigator grant, 12 ARC Discovery and NHMRC Project grants and a Simons Foundation grant as Chief Investigator A, as well as numerous other national and international grants as a co-CI. He has trained over 30 PhD students and postdocs, many of whom are now faculty members in universities worldwide, or work as scientists in tech companies such as Google Deepmind. From 2005-2010 he was Editor-in-Chief of the journal Network: Computation in Neural Systems, and he is currently on the Editorial Boards of Neural Computation and Brain Informatics. He has reviewed manuscripts for over 60 different journals and grants for 15 different research agencies worldwide. In 2006 he founded the Australian Workshop on Computational Neuroscience which now runs annually, and in 2015 he founded the Systems and Computational Neuroscience DownUnder (SCiNDU) conference which now runs bi-annually. During his career he has taught courses in Medical Neuroscience, Developmental Neuroscience, Mathematical Neuroscienc, Numeral Methods and Scientific Computing. Besides giving many radio interviews and public lectures about his work he has also written several articles for The Conversation and given a TEDx talk.
Journal Article: Behavioral signatures of a developing neural code
Avitan, Lilach, Pujic, Zac, Mölter, Jan, McCullough, Michael, Zhu, Shuyu, Sun, Biao, Myhre, Ann-Elin and Goodhill, Geoffrey J. (2020). Behavioral signatures of a developing neural code. Current Biology, 30 (17), 3352-3363.e5. doi: 10.1016/j.cub.2020.06.040
Journal Article: Detecting neural assemblies in calcium imaging data
Mölter, Jan, Avitan, Lilach and Goodhill, Geoffrey J. (2018). Detecting neural assemblies in calcium imaging data. BMC Biology, 16 (1) 143, 143. doi: 10.1186/s12915-018-0606-4
Journal Article: Code under construction: neural coding over development
Avitan, Lilach and Goodhill, Geoffrey J (2018). Code under construction: neural coding over development. Trends in Neurosciences, 41 (9), 599-609. doi: 10.1016/j.tins.2018.05.011
Journal Article: Estimating cortical feature maps with dependent Gaussian processes
Hughes, Nicholas J. and Goodhill, Geoffrey J. (2017). Estimating cortical feature maps with dependent Gaussian processes. IEEE Transactions On Pattern Analysis and Machine Intelligence, 39 (10) 7731172, 1918-1928. doi: 10.1109/TPAMI.2016.2624295
Journal Article: Spontaneous Activity in the Zebrafish Tectum Reorganizes over Development and Is Influenced by Visual Experience
Avitan, Lilach, Goodhill, Geoffrey J., Pujic, Zac, Molter, Jan, Van De Poll, Matthew, Sun, Biao, Teng, Haotian, Amor, Rumelo and Scott, Ethan K. (2017). Spontaneous Activity in the Zebrafish Tectum Reorganizes over Development and Is Influenced by Visual Experience. Current Biology, 27 (16), 2407-2419. doi: 10.1016/j.cub.2017.06.056
Journal Article: Sensory experience modifies feature map relationships in visual cortex
Cloherty, Shaun L., Hughes, Nicholas J., Hietanen, Markus A., Bhagavatula, Partha S., Goodhill, Geoffrey J. and Ibbotson, Michael R. (2016). Sensory experience modifies feature map relationships in visual cortex. eLife, 5 (JUN2016) e13911. doi: 10.7554/eLife.13911
Journal Article: Limitations of neural map topography for decoding spatial information
Avitan, Lilach, Pujic, Zac, Hughes, Nicholas J., Scott, Ethan K. and Goodhill, Geoffrey J. (2016). Limitations of neural map topography for decoding spatial information. Journal of Neuroscience, 36 (19), 5385-5396. doi: 10.1523/JNEUROSCI.0385-16.2016
Journal Article: Can molecular gradients wire the brain?
Goodhill, Geoffrey J. (2016). Can molecular gradients wire the brain?. Trends in Neurosciences, 39 (4), 202-211. doi: 10.1016/j.tins.2016.01.009
Conference Publication: Emergence of ion channel modal gating from independent subunit kinetics
Bicknell, Brendan A. and Goodhill, Geoffrey J. (2016). Emergence of ion channel modal gating from independent subunit kinetics. Washington, DC, United States: National Academy of Sciences. doi: 10.1073/pnas.1604090113
Journal Article: The limits of chemosensation vary across dimensions
Bicknell, Brendan A., Dayan, Peter and Goodhill, Geoffrey J. (2015). The limits of chemosensation vary across dimensions. Nature Communications, 6 (7468) 7468, 1-8. doi: 10.1038/ncomms8468
Journal Article: The dynamics of growth cone morphology
Goodhill, Geoffrey J., Faville, Richard A., Sutherland, Daniel J., Bicknell, Brendan A., Thompson, Andrew W., Pujic, Zac, Sun, Biao, Kita, Elizabeth M. and Scott, Ethan K. (2015). The dynamics of growth cone morphology. BMC Biology, 13 (10) 10, 1-16. doi: 10.1186/s12915-015-0115-7
Journal Article: Balanced interhemispheric cortical activity is required for correct targeting of the corpus callosum
Suarez, Rodrigo, Fenlon, Laura R., Marek, Roger, Avitan, Lilach A, Sah, Pankaj, Goodhill, Geoffrey J. and Richards, Linda J. (2014). Balanced interhemispheric cortical activity is required for correct targeting of the corpus callosum. Neuron, 82 (6), 1289-1298. doi: 10.1016/j.neuron.2014.04.040
Journal Article: Calcium signaling in axon guidance
Sutherland, Daniel J., Pujic, Zac and Goodhill, Geoffrey J. (2014). Calcium signaling in axon guidance. Trends in Neurosciences, 37 (8), 424-432. doi: 10.1016/j.tins.2014.05.008
Journal Article: Calcium and cAMP levels interact to determine attraction versus repulsion in axon guidance
Forbes, Elizabeth M., Thompson, Andrew W., Yuan, Jiajia and Goodhill, Geoffrey J. (2012). Calcium and cAMP levels interact to determine attraction versus repulsion in axon guidance. Neuron, 74 (3), 490-503. doi: 10.1016/j.neuron.2012.02.035
Journal Article: Axon guidance by growth-rate modulation
Mortimer, D., Pujic, Z., Vaughan, T., Thompson, A. W., Feldner, J., Vetter, I. and Goodhill, G. J. (2010). Axon guidance by growth-rate modulation. Proceedings of the National Academy of Sciences of the United States of America, 107 (11), 5202-5207. doi: 10.1073/pnas.0909254107
Journal Article: A Bayesian model predicts the response of axons to molecular gradients
Mortimer, Duncan, Feldner, Julia, Vaughan, Timothy, Vetter, Irina, Pujic, Zac, Rosoff, William J., Burrage, Kevin, Dayan, Peter, Richards, Linda J. and Goodhill, Geoffrey J. (2009). A Bayesian model predicts the response of axons to molecular gradients. Proceedings of the National Academy of Sciences of the United States of America, 106 (25), 10296-10301. doi: 10.1073/pnas.0900715106
Journal Article: Growth cone chemotaxis
Mortimer, Duncan, Fothergill, Thomas, Pujic, Zac, Richards, Linda J. and Goodhill, Geoffrey J. (2008). Growth cone chemotaxis. Trends in Neurosciences, 31 (2), 90-98. doi: 10.1016/j.tins.2007.11.008
Journal Article: Contributions of theoretical modeling to the understanding of neural map development
Goodhill, G. J. (2007). Contributions of theoretical modeling to the understanding of neural map development. Neuron, 56 (2), 301-311. doi: 10.1016/j.neuron.2007.09.027
Journal Article: A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients
Rosoff, W. J., Urbach, J. S., Esrick, M. A., McAllister, R. G., Richards, L. J. and Goodhill, G. J. (2004). A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients. Nature Neuroscience, 7 (6), 678-682. doi: 10.1038/nn1259
How does environmental enrichment affect brain development?
(2021–2023) ARC Discovery Projects
Mapping neurodevelopmental disorders in a zebrafish model
(2021) NHMRC Investigator Grants
(2020–2023) Breast Cancer Research Program
Information processing in the developing zebrafish brain
(2020) Doctor Philosophy
Neural encoding models for multivariate optical imaging data
(2020) Doctor Philosophy
Investigating the links between spontaneous activity and behaviour in the zebrafish optic tectum
(2018) Master Philosophy
Behavioral signatures of a developing neural code
Avitan, Lilach, Pujic, Zac, Mölter, Jan, McCullough, Michael, Zhu, Shuyu, Sun, Biao, Myhre, Ann-Elin and Goodhill, Geoffrey J. (2020). Behavioral signatures of a developing neural code. Current Biology, 30 (17), 3352-3363.e5. doi: 10.1016/j.cub.2020.06.040
Detecting neural assemblies in calcium imaging data
Mölter, Jan, Avitan, Lilach and Goodhill, Geoffrey J. (2018). Detecting neural assemblies in calcium imaging data. BMC Biology, 16 (1) 143, 143. doi: 10.1186/s12915-018-0606-4
Code under construction: neural coding over development
Avitan, Lilach and Goodhill, Geoffrey J (2018). Code under construction: neural coding over development. Trends in Neurosciences, 41 (9), 599-609. doi: 10.1016/j.tins.2018.05.011
Estimating cortical feature maps with dependent Gaussian processes
Hughes, Nicholas J. and Goodhill, Geoffrey J. (2017). Estimating cortical feature maps with dependent Gaussian processes. IEEE Transactions On Pattern Analysis and Machine Intelligence, 39 (10) 7731172, 1918-1928. doi: 10.1109/TPAMI.2016.2624295
Avitan, Lilach, Goodhill, Geoffrey J., Pujic, Zac, Molter, Jan, Van De Poll, Matthew, Sun, Biao, Teng, Haotian, Amor, Rumelo and Scott, Ethan K. (2017). Spontaneous Activity in the Zebrafish Tectum Reorganizes over Development and Is Influenced by Visual Experience. Current Biology, 27 (16), 2407-2419. doi: 10.1016/j.cub.2017.06.056
Sensory experience modifies feature map relationships in visual cortex
Cloherty, Shaun L., Hughes, Nicholas J., Hietanen, Markus A., Bhagavatula, Partha S., Goodhill, Geoffrey J. and Ibbotson, Michael R. (2016). Sensory experience modifies feature map relationships in visual cortex. eLife, 5 (JUN2016) e13911. doi: 10.7554/eLife.13911
Limitations of neural map topography for decoding spatial information
Avitan, Lilach, Pujic, Zac, Hughes, Nicholas J., Scott, Ethan K. and Goodhill, Geoffrey J. (2016). Limitations of neural map topography for decoding spatial information. Journal of Neuroscience, 36 (19), 5385-5396. doi: 10.1523/JNEUROSCI.0385-16.2016
Can molecular gradients wire the brain?
Goodhill, Geoffrey J. (2016). Can molecular gradients wire the brain?. Trends in Neurosciences, 39 (4), 202-211. doi: 10.1016/j.tins.2016.01.009
Emergence of ion channel modal gating from independent subunit kinetics
Bicknell, Brendan A. and Goodhill, Geoffrey J. (2016). Emergence of ion channel modal gating from independent subunit kinetics. Washington, DC, United States: National Academy of Sciences. doi: 10.1073/pnas.1604090113
The limits of chemosensation vary across dimensions
Bicknell, Brendan A., Dayan, Peter and Goodhill, Geoffrey J. (2015). The limits of chemosensation vary across dimensions. Nature Communications, 6 (7468) 7468, 1-8. doi: 10.1038/ncomms8468
The dynamics of growth cone morphology
Goodhill, Geoffrey J., Faville, Richard A., Sutherland, Daniel J., Bicknell, Brendan A., Thompson, Andrew W., Pujic, Zac, Sun, Biao, Kita, Elizabeth M. and Scott, Ethan K. (2015). The dynamics of growth cone morphology. BMC Biology, 13 (10) 10, 1-16. doi: 10.1186/s12915-015-0115-7
Balanced interhemispheric cortical activity is required for correct targeting of the corpus callosum
Suarez, Rodrigo, Fenlon, Laura R., Marek, Roger, Avitan, Lilach A, Sah, Pankaj, Goodhill, Geoffrey J. and Richards, Linda J. (2014). Balanced interhemispheric cortical activity is required for correct targeting of the corpus callosum. Neuron, 82 (6), 1289-1298. doi: 10.1016/j.neuron.2014.04.040
Calcium signaling in axon guidance
Sutherland, Daniel J., Pujic, Zac and Goodhill, Geoffrey J. (2014). Calcium signaling in axon guidance. Trends in Neurosciences, 37 (8), 424-432. doi: 10.1016/j.tins.2014.05.008
Calcium and cAMP levels interact to determine attraction versus repulsion in axon guidance
Forbes, Elizabeth M., Thompson, Andrew W., Yuan, Jiajia and Goodhill, Geoffrey J. (2012). Calcium and cAMP levels interact to determine attraction versus repulsion in axon guidance. Neuron, 74 (3), 490-503. doi: 10.1016/j.neuron.2012.02.035
Axon guidance by growth-rate modulation
Mortimer, D., Pujic, Z., Vaughan, T., Thompson, A. W., Feldner, J., Vetter, I. and Goodhill, G. J. (2010). Axon guidance by growth-rate modulation. Proceedings of the National Academy of Sciences of the United States of America, 107 (11), 5202-5207. doi: 10.1073/pnas.0909254107
A Bayesian model predicts the response of axons to molecular gradients
Mortimer, Duncan, Feldner, Julia, Vaughan, Timothy, Vetter, Irina, Pujic, Zac, Rosoff, William J., Burrage, Kevin, Dayan, Peter, Richards, Linda J. and Goodhill, Geoffrey J. (2009). A Bayesian model predicts the response of axons to molecular gradients. Proceedings of the National Academy of Sciences of the United States of America, 106 (25), 10296-10301. doi: 10.1073/pnas.0900715106
Mortimer, Duncan, Fothergill, Thomas, Pujic, Zac, Richards, Linda J. and Goodhill, Geoffrey J. (2008). Growth cone chemotaxis. Trends in Neurosciences, 31 (2), 90-98. doi: 10.1016/j.tins.2007.11.008
Contributions of theoretical modeling to the understanding of neural map development
Goodhill, G. J. (2007). Contributions of theoretical modeling to the understanding of neural map development. Neuron, 56 (2), 301-311. doi: 10.1016/j.neuron.2007.09.027
A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients
Rosoff, W. J., Urbach, J. S., Esrick, M. A., McAllister, R. G., Richards, L. J. and Goodhill, G. J. (2004). A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients. Nature Neuroscience, 7 (6), 678-682. doi: 10.1038/nn1259
Axon guidance studies using a microfluidics-based chemotropic gradient generator
Pujic, Zac, Nguyen, Huyen, Glass, Nick, Cooper-White, Justin and Goodhill, Geoffrey J. (2016). Axon guidance studies using a microfluidics-based chemotropic gradient generator. In 2nd (Ed.), Chemotaxis: methods and protocols (pp. 273-285) New York, NY United States: Springer New York. doi:10.1007/978-1-4939-3480-5_20
Mortimer, Duncan, Simpson, Hugh D. and Goodhill, Geoffrey J. (2012). Axonal growth and targeting. Computational systems neurobiology. (pp. 429-458) edited by Nicolas Le Novère. Dordrecht, Netherlands: Springer. doi: 10.1007/978-94-007-3858-4_14
Mortimer, D. and Goodhill, G. J. (2009). Axonal Pathfinding. Encyclopedia of Neuroscience. (pp. 1133-1138) edited by Marc D. Binder, Nobutaka Hirokawa and Uwe Windhorst. Berlin, Germany: Elsevier Ltd. doi: 10.1016/B978-008045046-9.01412-1
Quantitative studies of neuronal chemotaxis in 3D
Rosoff, William J., McAllister, Ryan G., Goodhill, Geoffrey J. and Urbach, Jeffrey S. (2009). Quantitative studies of neuronal chemotaxis in 3D. Chemotaxis: methods and protocols. (pp. 239-254) edited by Tian Jin and Dale Hereld. New York, United States: Humana Press. doi: 10.1007/978-1-60761-198-1
Unsupervised quantification of naturalistic animal behaviors for gaining insight into the brain
McCullough, Michael H. and Goodhill, Geoffrey J. (2021). Unsupervised quantification of naturalistic animal behaviors for gaining insight into the brain. Current Opinion in Neurobiology, 70, 89-100. doi: 10.1016/j.conb.2021.07.014
Zebrafish chromosome 14 gene differential expression in the fmr1hu2787 model of Fragile X Syndrome
Barthelson, Karissa, Baer, Lachlan, Dong, Yang, Hand, Melanie, Pujic, Zac, Newman, Morgan, Goodhill, Geoffrey J., Richards, Robert I., Pederson, Stephen M. and Lardelli, Michael (2021). Zebrafish chromosome 14 gene differential expression in the fmr1hu2787 model of Fragile X Syndrome. Frontiers in Genetics, 12 625466, 625466. doi: 10.3389/fgene.2021.625466
Spontaneous and evoked activity patterns diverge over development
Avitan, Lilach, Pujic, Zac, Mölter, Jan, Zhu, Shuyu, Sun, Biao and Goodhill, Geoffrey J. (2021). Spontaneous and evoked activity patterns diverge over development. eLife, 10 e61942, 1-12. doi: 10.7554/elife.61942
Gormal, Rachel S., Padmanabhan, Pranesh, Kasula, Ravikiran, Bademosi, Adekunle T., Coakley, Sean, Giacomotto, Jean, Blum, Ailisa, Joensuu, Merja, Wallis, Tristan P., Lo, Harriet P., Budnar, Srikanth, Rae, James, Ferguson, Charles, Bastiani, Michele, Thomas, Walter G., Pardon, Els, Steyaert, Jan, Yap, Alpha S., Goodhill, Geoffrey J., Hilliard, Massimo A., Parton, Robert G. and Meunier, Frédéric A. (2020). Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies. Proceedings of the National Academy of Sciences of the United States of America, 117 (48), 30476-30487. doi: 10.1073/pnas.2007443117
Model-based decoupling of evoked and spontaneous neural activity in calcium imaging data
Triplett, Marcus A., Pujic, Zac, Sun, Biao, Avitan, Lilach and Goodhill, Geoffrey J. (2020). Model-based decoupling of evoked and spontaneous neural activity in calcium imaging data. Plos Computational Biology, 16 (11), e1008330. doi: 10.1371/journal.pcbi.1008330
Spare a thought for longitudinal diversity
Goodhill, Geoff (2020). Spare a thought for longitudinal diversity. Nature, 587 (7833), 320-320. doi: 10.1038/d41586-020-03017-6
Altered brain-wide auditory networks in a zebrafish model of fragile X syndrome
Constantin, Lena, Poulsen, Rebecca E., Scholz, Leandro A., Favre-Bulle, Itia A., Taylor, Michael A., Sun, Biao, Goodhill, Geoffrey J., Vanwalleghem, Gilles C. and Scott, Ethan K. (2020). Altered brain-wide auditory networks in a zebrafish model of fragile X syndrome. BMC Biology, 18 (1) 125, 125. doi: 10.1186/s12915-020-00857-6
Correction: Behavioral signatures of a developing neural code
Avitan, Lilach, Pujic, Zac, Mölter, Jan, McCullough, Michael, Zhu, Shuyu, Sun, Biao, Myhre, Ann-Elin and Goodhill, Geoffrey J. (2020). Correction: Behavioral signatures of a developing neural code. Current Biology, 30 (17), 3491-3493. doi: 10.1016/j.cub.2020.08.009
Behavioral signatures of a developing neural code
Avitan, Lilach, Pujic, Zac, Mölter, Jan, McCullough, Michael, Zhu, Shuyu, Sun, Biao, Myhre, Ann-Elin and Goodhill, Geoffrey J. (2020). Behavioral signatures of a developing neural code. Current Biology, 30 (17), 3352-3363.e5. doi: 10.1016/j.cub.2020.06.040
Limitations to estimating mutual information in large neural populations
Mölter, Jan and Goodhill, Geoffrey J. (2020). Limitations to estimating mutual information in large neural populations. Entropy, 22 (4) 490, 1-12. doi: 10.3390/e22040490
Mölter, Jan, Avitan, Lilach and Goodhill, Geoffrey J. (2019). Correction to: Detecting neural assemblies in calcium imaging data (BMC Biology (2018) 16 (143) DOI: 10.1186/s12915-018-0606-4). BMC Biology, 17 (1) 21, 21. doi: 10.1186/s12915-019-0644-6
Probabilistic encoding models for multivariate neural data
Triplett, Marcus A. and Goodhill, Geoffrey J. (2019). Probabilistic encoding models for multivariate neural data. Frontiers in Neural Circuits, 13 1, 1. doi: 10.3389/fncir.2019.00001
Detecting neural assemblies in calcium imaging data
Mölter, Jan, Avitan, Lilach and Goodhill, Geoffrey J. (2018). Detecting neural assemblies in calcium imaging data. BMC Biology, 16 (1) 143, 143. doi: 10.1186/s12915-018-0606-4
Theoretical Models of Neural Development
Goodhill, Geoffrey J. (2018). Theoretical Models of Neural Development. Iscience, 8, 183-199. doi: 10.1016/j.isci.2018.09.017
Emergence of spontaneous assembly activity in developing neural networks without afferent input
Triplett, Marcus A., Avitan, Lilach and Goodhill, Geoffrey J. (2018). Emergence of spontaneous assembly activity in developing neural networks without afferent input. PLoS Computational Biology, 14 (9) e1006421, e1006421. doi: 10.1371/journal.pcbi.1006421
Bicknell, Brendan A., Pujic, Zac, Feldner, Julia, Vetter, Irina and Goodhill, Geoffrey J. (2018). Data descriptor: chemotactic responses of growing neurites to precisely controlled gradients of nerve growth factor. Scientific Data, 5 (1) 180183, 180183. doi: 10.1038/sdata.2018.183
Control of neurite growth and guidance by an inhibitory cell-body signal
Bicknell, Brendan A., Pujic, Zac, Dayan, Peter and Goodhill, Geoffrey J. (2018). Control of neurite growth and guidance by an inhibitory cell-body signal. PLoS Computational Biology, 14 (6) e1006218, e1006218. doi: 10.1371/journal.pcbi.1006218
Marachlian, Emiliano, Avitan, Lilach, Goodhill, Geoffrey J. and Sumbre, German (2018). Principles of functional circuit connectivity: insights from spontaneous activity in the zebrafish optic tectum. Frontiers in Neural Circuits, 12 46, 46. doi: 10.3389/fncir.2018.00046
Code under construction: neural coding over development
Avitan, Lilach and Goodhill, Geoffrey J (2018). Code under construction: neural coding over development. Trends in Neurosciences, 41 (9), 599-609. doi: 10.1016/j.tins.2018.05.011
Axon growth regulation by a bistable molecular switch
Padmanabhan, Pranesh and Goodhill, Geoffrey J. (2018). Axon growth regulation by a bistable molecular switch. Proceedings of the Royal Society of London B: Biological Sciences, 285 (1877) 20172618, 20172618. doi: 10.1098/rspb.2017.2618
Joensuu, Merja, Martinez-Marmol, Ramon, Padmanabhan, Pranesh, Glass, Nick R., Durisic, Nela, Pelekanos, Matthew, Mollazade, Mahdie, Balistreri, Giuseppe, Amor, Rumelo, Cooper-White, Justin J., Goodhill, Geoffrey J. and Meunier, Frederic A. (2017). Visualizing endocytic recycling and trafficking in live neurons by subdiffractional tracking of internalized molecules. Nature Protocols, 12 (12), 2590-2622. doi: 10.1038/nprot.2017.116
A Three-Layer Network Model of Direction Selective Circuits in the Optic Tectum
Abbas, Fatima, Triplett, Marcus A., Goodhill, Geoffrey J. and Meyer, Martin P. (2017). A Three-Layer Network Model of Direction Selective Circuits in the Optic Tectum. Frontiers in Neural Circuits, 11 88, 88. doi: 10.3389/fncir.2017.00088
Estimating cortical feature maps with dependent Gaussian processes
Hughes, Nicholas J. and Goodhill, Geoffrey J. (2017). Estimating cortical feature maps with dependent Gaussian processes. IEEE Transactions On Pattern Analysis and Machine Intelligence, 39 (10) 7731172, 1918-1928. doi: 10.1109/TPAMI.2016.2624295
Avitan, Lilach, Goodhill, Geoffrey J., Pujic, Zac, Molter, Jan, Van De Poll, Matthew, Sun, Biao, Teng, Haotian, Amor, Rumelo and Scott, Ethan K. (2017). Spontaneous Activity in the Zebrafish Tectum Reorganizes over Development and Is Influenced by Visual Experience. Current Biology, 27 (16), 2407-2419. doi: 10.1016/j.cub.2017.06.056
Bademosi, Adekunle T., Lauwers, Elsa, Padmanabhan, Pranesh, Odierna, Lorenzo, Chai, Ye Jin, Papadopulos, Andreas, Goodhill, Geoffrey J., Verstreken, Patrik, van Swinderen, Bruno and Meunier, Frédéric A (2017). Erratum: In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters. Nature Communications, 8 (1) 14492. doi: 10.1038/ncomms14492
Bademosi, Adekunle T., Lauwers, Elsa, Padmanabhan, Pranesh, Odierna, Lorenzo, Chai, Ye Jin, Papadopulos, Andreas, Goodhill, Geoffrey J., Verstreken, Patrik, Van Swinderen, Bruno and Meunier, Frederic A. (2016). In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters. Nature Communications, 7 (1) 13660, 13660. doi: 10.1038/ncomms13660
Joensuu, Merja, Padmanabhan, Pranesh, Durisic, Nela, Bademosi, Adekunle T. D., Cooper-Williams, Elizabeth, Morrow, Isabel C., Harper, Callista B., Jung, WooRam, Parton, Robert G., Goodhill, Geoffrey J., Papadopulos, Andreas and Meunier, Frederic A. (2016). Subdiffractional tracking of internalized molecules reveals heterogeneous motion states of synaptic vesicles. Journal of Cell Biology, 215 (2), 277-292. doi: 10.1083/jcb.201604001
Sensory experience modifies feature map relationships in visual cortex
Cloherty, Shaun L., Hughes, Nicholas J., Hietanen, Markus A., Bhagavatula, Partha S., Goodhill, Geoffrey J. and Ibbotson, Michael R. (2016). Sensory experience modifies feature map relationships in visual cortex. eLife, 5 (JUN2016) e13911. doi: 10.7554/eLife.13911
Limitations of neural map topography for decoding spatial information
Avitan, Lilach, Pujic, Zac, Hughes, Nicholas J., Scott, Ethan K. and Goodhill, Geoffrey J. (2016). Limitations of neural map topography for decoding spatial information. Journal of Neuroscience, 36 (19), 5385-5396. doi: 10.1523/JNEUROSCI.0385-16.2016
Can molecular gradients wire the brain?
Goodhill, Geoffrey J. (2016). Can molecular gradients wire the brain?. Trends in Neurosciences, 39 (4), 202-211. doi: 10.1016/j.tins.2016.01.009
Quantitative analysis of axonal branch dynamics in the developing nervous system
Chalmers, Kelsey, Kita, Elizabeth M., Scott, Ethan K. and Goodhill, Geoffrey J. (2016). Quantitative analysis of axonal branch dynamics in the developing nervous system. PLoS Computational Biology, 12 (3) e1004813, e1004813. doi: 10.1371/journal.pcbi.1004813
The limits of chemosensation vary across dimensions
Bicknell, Brendan A., Dayan, Peter and Goodhill, Geoffrey J. (2015). The limits of chemosensation vary across dimensions. Nature Communications, 6 (7468) 7468, 1-8. doi: 10.1038/ncomms8468
Goodhill, Geoffrey J. (2015). Introduction to the special issue on from maps to circuits: models and mechanisms for generating neural connections. Developmental Neurobiology, 75 (6), 539-541. doi: 10.1002/dneu.22270
The dynamics of growth cone morphology
Goodhill, Geoffrey J., Faville, Richard A., Sutherland, Daniel J., Bicknell, Brendan A., Thompson, Andrew W., Pujic, Zac, Sun, Biao, Kita, Elizabeth M. and Scott, Ethan K. (2015). The dynamics of growth cone morphology. BMC Biology, 13 (10) 10, 1-16. doi: 10.1186/s12915-015-0115-7
How deeply does your mutant sleep? Probing arousal to better understand sleep defects in Drosophila
Faville, R., Kottler, B., Goodhill, G. J., Shaw, P. J. and van Swinderen, B. (2015). How deeply does your mutant sleep? Probing arousal to better understand sleep defects in Drosophila. Scientific Reports, 5 (1) 8454, 1-13. doi: 10.1038/srep08454
Optimizing the representation of orientation preference maps in visual cortex
Hughes, Nicholas J. and Goodhill, Geoffrey J. (2015). Optimizing the representation of orientation preference maps in visual cortex. Neural Computation, 27 (1), 32-41. doi: 10.1162/NECO_a_00687
Topographic wiring of the retinotectal connection in zebrafish
Kita, Elizabeth M, Scott, Ethan K and Goodhill, Geoffrey J (2015). Topographic wiring of the retinotectal connection in zebrafish. Developmental Neurobiology, 75 (6), 542-556. doi: 10.1002/dneu.22256
How receptor diffusion influences gradient sensing
Nguyen, H., Dayan, P. and Goodhill, G. J. (2015). How receptor diffusion influences gradient sensing. Journal of the Royal Society: Interface, 12 (102) 20141097, 1-8. doi: 10.1098/rsif.2014.1097
Xu, Jun, Rosoff, William J., Urbach, Jeffrey S. and Goodhill, Geoffrey J. (2015). Adaptation is not required to explain the long-term response of axons to molecular gradients [correction]. Development (Cambridge), 142 (13), 2385-2385. doi: 10.1242/dev.127316
The influence of activity on axon pathfinding in the optic tectum
Kita, Elizabeth M., Scott, Ethan K. and Goodhill, Geoffrey J. (2015). The influence of activity on axon pathfinding in the optic tectum. Developmental Neurobiology, 75 (6), 608-620. doi: 10.1002/dneu.22262
The interdependent roles of Ca2+ and cAMP in axon guidance
Sutherland, Daniel J. and Goodhill, Geoffrey J. (2015). The interdependent roles of Ca2+ and cAMP in axon guidance. Developmental Neurobiology, 75 (4), 402-410. doi: 10.1002/dneu.22144
The influence of receptor positioning on chemotactic information
Nguyen, H., Dayan, P. and Goodhill, G. J. (2014). The influence of receptor positioning on chemotactic information. Journal of Theoretical Biology, 360, 95-101. doi: 10.1016/j.jtbi.2014.06.022
Stripe-rearing changes multiple aspects of the structure of primary visual cortex
Hughes, Nicholas J., Hunt, Jonathan J., Cloherty, Shaun L., Ibbotson, Michael R., Sengpiel, Frank and Goodhill, Geoffrey J. (2014). Stripe-rearing changes multiple aspects of the structure of primary visual cortex. NeuroImage, 95, 305-319. doi: 10.1016/j.neuroimage.2014.03.031
Balanced interhemispheric cortical activity is required for correct targeting of the corpus callosum
Suarez, Rodrigo, Fenlon, Laura R., Marek, Roger, Avitan, Lilach A, Sah, Pankaj, Goodhill, Geoffrey J. and Richards, Linda J. (2014). Balanced interhemispheric cortical activity is required for correct targeting of the corpus callosum. Neuron, 82 (6), 1289-1298. doi: 10.1016/j.neuron.2014.04.040
Davis, F. M., Azimi, I., Faville, R. A., Peters, A. A., Jalink, K., Putney Jr, J. W., Goodhill, G. J., Thompson, E. W., Roberts-Thomson, S. J. and Monteith, G. R. (2014). Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent. Oncogene, 33 (18), 2307-2316. doi: 10.1038/onc.2013.187
Open access: Practical costs of data sharing
Goodhill, Geoffrey J. (2014). Open access: Practical costs of data sharing. Nature, 509 (7498), 33-33. doi: 10.1038/509033b
A computational model of the effect of gene misexpression on the development of cortical areas
Giacomantonio, Clare E. and Goodhill, Geoffrey J. (2014). A computational model of the effect of gene misexpression on the development of cortical areas. Biological Cybernetics, 108 (2), 203-221. doi: 10.1007/s00422-014-0590-x
Calcium signaling in axon guidance
Sutherland, Daniel J., Pujic, Zac and Goodhill, Geoffrey J. (2014). Calcium signaling in axon guidance. Trends in Neurosciences, 37 (8), 424-432. doi: 10.1016/j.tins.2014.05.008
Fothergill, Thomas, Donahoo, Amber-Lee S., Douglass, Amelia, Zalucki, Oressia, Yuan, Jiajia, Shu, Tianzhi, Goodhill, Geoffrey J. and Richards, Linda J. (2014). Netrin-DCC signaling regulates corpus callosum formation through attraction of pioneering axons and by modulating Slit2-mediated repulsion. Cerebral Cortex, 24 (5), 1138-1151. doi: 10.1093/cercor/bhs395
Hunt, Jonathan J., Dayan, Peter and Goodhill, Geoffrey J. (2013). Sparse coding can predict primary visual cortex receptive field changes induced by abnormal visual input. PLoS Computational Biology, 9 (5) e1003005, e1003005.1-e1003005.17. doi: 10.1371/journal.pcbi.1003005
Simpson, Hugh D., Kita, Elizabeth M., Scott, Ethan K. and Goodhill, Geoffrey J. (2013). A quantitative analysis of branching, growth cone turning and directed growth in zebrafish retinotectal axon guidance. Journal of Comparative Neurology, 521 (6), 1409-1429. doi: 10.1002/cne.23248
A dual compartment diffusion chamber for studying axonal chemotaxis in 3D collagen
Pujic, Zac and Goodhill, Geoffrey J. (2013). A dual compartment diffusion chamber for studying axonal chemotaxis in 3D collagen. Journal of Neuroscience Methods, 215 (1), 53-59. doi: 10.1016/j.jneumeth.2013.02.008
Optimality and saturation in axonal chemotaxis
Yuan, Jiajia, Chan, Stanley, Mortimer, Duncan, Nguyen, Huyen and Goodhill, Geoffrey J. (2013). Optimality and saturation in axonal chemotaxis. Neural Computation, 25 (4), 833-853. doi: 10.1162/NECO_a_00426
Randomly oriented edge arrangements dominate naturalistic arrangements in binocular rivalry
Hunt, Jonathan J., Mattingley, Jason B. and Goodhill, Geoffrey J. (2012). Randomly oriented edge arrangements dominate naturalistic arrangements in binocular rivalry. Vision Research, 64, 49-55. doi: 10.1016/j.visres.2012.05.007
Calcium and cAMP levels interact to determine attraction versus repulsion in axon guidance
Forbes, Elizabeth M., Thompson, Andrew W., Yuan, Jiajia and Goodhill, Geoffrey J. (2012). Calcium and cAMP levels interact to determine attraction versus repulsion in axon guidance. Neuron, 74 (3), 490-503. doi: 10.1016/j.neuron.2012.02.035
Sparse coding on the spot: Spontaneous retinal waves suffice for orientation selectivity
Hunt, Jonathan J., Ibbotson, Michael and Goodhill, Geoffrey J. (2012). Sparse coding on the spot: Spontaneous retinal waves suffice for orientation selectivity. Neural Computation, 24 (24), 2422-2433. doi: 10.1162/NECO_a_00333
The combinatorics of neurite self-avoidance
Forbes, Elizabeth M., Hunt, Jonathan J. and Goodhill, Geoffrey J. (2011). The combinatorics of neurite self-avoidance. Neural Computation, 23 (11), 2746-2769. doi: 10.1162/NECO_a_00186
Computational modeling of neuronal map development: insights into disease
Simpson, Hugh D., Giacomantonio, Clare and Goodhill, Geoffrey J. (2011). Computational modeling of neuronal map development: insights into disease. Future Neurology, 6 (3), 339-349. doi: 10.2217/fnl.11.10
Cyclic nucleotide-dependent switching of mammalian axon guidance depends on gradient steepness
Thompson, Andrew W., Pujic, Zac, Richards, Linda J. and Goodhill, Geoffrey J. (2011). Cyclic nucleotide-dependent switching of mammalian axon guidance depends on gradient steepness. Molecular and Cellular Neuroscience, 47 (1), 45-52. doi: 10.1016/j.mcn.2011.02.012
A simple model can unify a broad range of phenomena in retinotectal map development
Simpson, Hugh D. and Goodhill, Geoffrey J. (2011). A simple model can unify a broad range of phenomena in retinotectal map development. Biological Cybernetics, 104 (1-2), 9-29. doi: 10.1007/s00422-011-0417-y
Mortimer, Duncan, Dayan, Peter, Burrage, Kevin and Goodhill, Geoffrey J. (2011). Bayes-optimal chemotaxis. Neural Computation, 23 (2), 336-373. doi: 10.1162/NECO_a_00075
Statistical structure of lateral connections in the primary visual cortex
Hunt, Jonathan J., Bosking, William H. and Goodhill, Geoffrey J. (2011). Statistical structure of lateral connections in the primary visual cortex. Neural Systems and Circuits, 1 (3) 3, 1-23. doi: 10.1186/2042-1001-1-3
A boolean model of the gene regulatory network underlying mammalian cortical area development
Giacomantonio, Clare E. and Goodhill, Geoffrey J. (2010). A boolean model of the gene regulatory network underlying mammalian cortical area development. Plos Computational Biology, 6 (9) e1000936, e1000936-1-e1000936-13. doi: 10.1371/journal.pcbi.1000936
The influence of restricted orientation rearing on map structure in primary visual cortex
Giacomantonio, CE, Ibbotson, MR and Goodhill, GJ (2010). The influence of restricted orientation rearing on map structure in primary visual cortex. NeuroImage, 52 (3), 875-883. doi: 10.1016/j.neuroimage.2009.12.066
The response of dorsal root ganglion axons to nerve growth factor gradients depends on spinal level
Vetter, I, Pujic, Z and Goodhill, GJ (2010). The response of dorsal root ganglion axons to nerve growth factor gradients depends on spinal level. Journal of Neurotrauma, 27 (8), 1379-1386. doi: 10.1089/neu.2010.1279
Optimizing chemotaxis by measuring unbound-bound transitions
Mortimer, Duncan, Dayan, Peter, Burrage, Kevin and Goodhill, Geoffrey J. (2010). Optimizing chemotaxis by measuring unbound-bound transitions. Physica D: Nonlinear Phenomena, 239 (9), 477-484. doi: 10.1016/j.physd.2009.09.009
Analyzing neurite outgrowth from explants by fitting ellipses
Haines, Carmen and Goodhill, Geoffrey J. (2010). Analyzing neurite outgrowth from explants by fitting ellipses. Journal of Neuroscience Methods, 187 (1), 52-58. doi: 10.1016/j.jneumeth.2009.12.010
Axon guidance by growth-rate modulation
Mortimer, D., Pujic, Z., Vaughan, T., Thompson, A. W., Feldner, J., Vetter, I. and Goodhill, G. J. (2010). Axon guidance by growth-rate modulation. Proceedings of the National Academy of Sciences of the United States of America, 107 (11), 5202-5207. doi: 10.1073/pnas.0909254107
Assays for Eukaryotic Cell Chemotaxis
Pujic, Z, Mortimer, Duncan, Feldner, Julia and Goodhill, Geoffrey J. (2009). Assays for Eukaryotic Cell Chemotaxis. Combinatorial Chemistry & High Throughput Screening, 12 (6), 580-588. doi: 10.2174/138620709788681952
A Bayesian model predicts the response of axons to molecular gradients
Mortimer, Duncan, Feldner, Julia, Vaughan, Timothy, Vetter, Irina, Pujic, Zac, Rosoff, William J., Burrage, Kevin, Dayan, Peter, Richards, Linda J. and Goodhill, Geoffrey J. (2009). A Bayesian model predicts the response of axons to molecular gradients. Proceedings of the National Academy of Sciences of the United States of America, 106 (25), 10296-10301. doi: 10.1073/pnas.0900715106
Theoretical models of neural circuit development
Simpson, Hugh D., Mortimer, Duncan and Goodhill, Geoffrey J. (2009). Theoretical models of neural circuit development. Current Topics in Developmental Biology, 87, 1-51. doi: 10.1016/S0070-2153(09)01201-0
Natural scene statistics and the structure of orientation maps in the visual cortex
Hunt, J. J., Giacomantonio, C. E., Tang, H. J., Mortimer, D., Jaffer, S., Vorobyov, V., Ericksson, G., Sengpiel, F. and Goodhill, G. J. (2009). Natural scene statistics and the structure of orientation maps in the visual cortex. NeuroImage, 47 (1), 157-172. doi: 10.1016/j.neuroimage.2009.03.052
Goodhill, Geoffrey J. (2009). The error bars on impact. Network-Computation in Neural Systems, 20 (2), 47-48. doi: 10.1080/09548980902996761
Analysis of the growth cone turning assay for studying axon guidance
Pujic, Zac, Giacomantonio, Clare E., Unni, Divya, Rosoff, William J. and Goodhill, Geoffrey J. (2008). Analysis of the growth cone turning assay for studying axon guidance. Journal of Neuroscience Methods, 170 (2), 220-228. doi: 10.1016/j.jneumeth.2008.01.014
Network: Computation in Neural Systems: Editorial
Goodhill, Geoff, Baker, Curtis, Balasubramanian, Vijay, Bazhenov, Maxim, Beck, Jeffrey, Becker, Sue, Bethge, Matthias, Boahen, Kwabena, Boden, Mikael, Bonin, Vincent, Bouret, Sebastien, Fairhall, Adrienne, Flash, Tamar, French, Robert, Gillies, Andrew, Gollisch, Tim, Gurney, Kevin, Gutkin, Boris, Hayhoe, Mary, Hunt, Jonathan, Ibbotson, Michael, Kepecs, Adam, Kingdom, Fred, Kropff, Emilio, Longden, Kit, Marder, Eve, Miikkulainen, Risto, Oliva, Aude, Olshausen, Bruno ... Zhaoping, Li (2008). Network: Computation in Neural Systems: Editorial. Network: Computation in Neural Systems, 19 (1), 1-2. doi: 10.1080/09548980801915409
Computation in neural systems. Editorial.
Goodhill, Geoff (2008). Computation in neural systems. Editorial.. Network-Computation in Neural Systems, 19 (1), 1-2. doi: 10.1080/09548980801915409
Mortimer, Duncan, Fothergill, Thomas, Pujic, Zac, Richards, Linda J. and Goodhill, Geoffrey J. (2008). Growth cone chemotaxis. Trends in Neurosciences, 31 (2), 90-98. doi: 10.1016/j.tins.2007.11.008
Contributions of theoretical modeling to the understanding of neural map development
Goodhill, G. J. (2007). Contributions of theoretical modeling to the understanding of neural map development. Neuron, 56 (2), 301-311. doi: 10.1016/j.neuron.2007.09.027
The effect of angioscotomas on map structure in primary visual cortex
Giacomantonio, C. E. and Goodhill, G. J. (2007). The effect of angioscotomas on map structure in primary visual cortex. Journal of Neuroscience, 27 (18), 4935-4946. doi: 10.1523/JNEUROSCI.1261-06.2007
Editorial: Welcome to the new Network
Goodhill, G. J. (2006). Editorial: Welcome to the new Network. Network-computation In Neural Systems, 17 (1), 1-2. doi: 10.1080/09548980600581758
A computational model for the development of multiple maps in primary visual cortex
Carreira-Perpinan, M. A., Lister, R. J. and Goodhill, G. J. (2005). A computational model for the development of multiple maps in primary visual cortex. Cerebral Cortex, 15 (8), 1222-1233. doi: 10.1093/cercor/bhi004
Adaptation is not required to explain the long-term response of axons to molecular gradients
Xu, J., Rosoff, W. J., Urbach, J. S. and Goodhill, G. J. (2005). Adaptation is not required to explain the long-term response of axons to molecular gradients. Development, 132 (20), 4545-4552. doi: 10.1242/dev.02029
Generating controlled molecular gradients in 3D gels
Rosoff, W. J., McAllister, R., Esrick, M. A., Goodhill, G. J. and Urbach, J. S. (2005). Generating controlled molecular gradients in 3D gels. Biotechnology And Bioengineering, 91 (6), 754-759. doi: 10.1002/bit.20564
The development of retinotectal maps: A review of models based on molecular gradients
Goodhill, Geoffrey J. and Xu, Jun (2005). The development of retinotectal maps: A review of models based on molecular gradients. Network-computation In Neural Systems, 16 (1), 5-34. doi: 10.1080/09548980500254654
Rosoff, WJ, Urbach, JS, Esrick, MA, McAllister, RG, Richards, LJ and Goodhill, GJ (2004). A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients (vol 7, pg 678, 2004). Nature Neuroscience, 7 (7), 785-785. doi: 10.1038/nn0704-785
A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients
Rosoff, W. J., Urbach, J. S., Esrick, M. A., McAllister, R. G., Richards, L. J. and Goodhill, G. J. (2004). A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients. Nature Neuroscience, 7 (6), 678-682. doi: 10.1038/nn1259
Influence of lateral connections on the structure of cortical maps
Carreira-Perpinan, M. A. and Goodhill, G. J. (2004). Influence of lateral connections on the structure of cortical maps. Journal of Neurophysiology, 92 (5), 2947-2959. doi: 10.1152/jn.00281.2004
Predicting axonal response to molecular gradients with a computational model of filopodial dynamics
Goodhill, G. J., Gu, M. and Urbach, J. S. (2004). Predicting axonal response to molecular gradients with a computational model of filopodial dynamics. Neural Computation, 16 (11), 2221-2243. doi: 10.1162/0899766041941934
A theoretical model of axon guidance by the Robo code
Goodhill, G. J. (2003). A theoretical model of axon guidance by the Robo code. Neural Computation, 15 (3), 549-564. doi: 10.1162/089976603321192077
Axon Guidance and Gradient Detection by Growth Cones
Goodhill, Geoffrey J. and Urbach, Jeffrey S. (2003). Axon Guidance and Gradient Detection by Growth Cones. Modeling Neural Development, 95-109.
Are visual cortex maps optimized for coverage?
Carreira-Perpinan, M. A. and Goodhill, G. J. (2002). Are visual cortex maps optimized for coverage?. Neural Computation, 14 (7), 1545-1560. doi: 10.1162/08997660260028601
Auto-SOM: recursive parameter estimation for guidance of self-organizing feature maps
Haese, K. and Goodhill, G. J. (2001). Auto-SOM: recursive parameter estimation for guidance of self-organizing feature maps. Neural Computation, 13 (3), 595-619. doi: 10.1162/089976601300014475
Dynamics of cortical map development in the elastic net model
Cimponeriu, A and Goodhill, GJ (2000). Dynamics of cortical map development in the elastic net model. Neurocomputing, 32, 83-90. doi: 10.1016/S0925-2312(00)00147-8
Goodhill, GJ and Cimponeriu, A (2000). Analysis of the elastic net model applied to the formation of ocular dominance and orientation columns. Network-Computation in Neural Systems, 11 (2), 153-168. doi: 10.1088/0954-898X/11/2/303
Dating behavior of the retinal ganglion cell
Goodhill, GJ (2000). Dating behavior of the retinal ganglion cell. Neuron, 25 (3), 501-503. doi: 10.1016/S0896-6273(00)81051-X
Retinotectal maps: molecules, models and misplaced data
Goodhill, GJ and Richards, LJ (1999). Retinotectal maps: molecules, models and misplaced data. Trends in Neurosciences, 22 (12), 529-534. doi: 10.1016/S0166-2236(99)01469-1
Theoretical analysis of gradient detection by growth cones
Goodhill, GJ and Urbach, JS (1999). Theoretical analysis of gradient detection by growth cones. Journal of Neurobiology, 41 (2), 230-241. doi: 10.1002/(SICI)1097-4695(19991105)41:2<230::AID-NEU6>3.0.CO;2-9
Limitations on detection of gradients of diffusible chemicals by axons
Urbach, JS and Goodhill, GJ (1999). Limitations on detection of gradients of diffusible chemicals by axons. Neurocomputing, 26-7, 39-43. doi: 10.1016/S0925-2312(99)00086-7
Goodhill, GJ (1998). The influence of neural activity and intracortical connectivity on the periodicity of ocular dominance stripes. Network-Computation in Neural Systems, 9 (3), 419-432. doi: 10.1088/0954-898X/9/3/009
Mathematical guidance for axons
Goodhill, GJ (1998). Mathematical guidance for axons. Trends in Neurosciences, 21 (6), 226-231. doi: 10.1016/S0166-2236(97)01203-4
Axon guidance: stretching gradients to the limit
Goodhill, G. J. and Baier, H. (1998). Axon guidance: stretching gradients to the limit. Neural Computation, 10 (3), 521-527. doi: 10.1162/089976698300017638
Stimulating issues in cortical map development
Goodhill, GJ (1997). Stimulating issues in cortical map development. Trends in Neurosciences, 20 (9), 375-376. doi: 10.1016/S0166-2236(97)01113-2
A unifying objective function for topographic mappings
Goodhill, G. J. and Sejnowski, T. J. (1997). A unifying objective function for topographic mappings. Neural Computation, 9 (6), 1291-1303. doi: 10.1162/neco.1997.9.6.1291
Goodhill, GJ (1997). Diffusion in axon guidance. European Journal of Neuroscience, 9 (7), 1414-1421. doi: 10.1111/j.1460-9568.1997.tb01496.x
Influences on the global structure of cortical maps
Goodhill, GJ, Bates, KR and Montague, PR (1997). Influences on the global structure of cortical maps. Proceedings of the Royal Society B-Biological Sciences, 264 (1382), 649-655. doi: 10.1098/rspb.1997.0092
Goodhill, GJ and Lowel, S (1995). Theory Meets Experiment - Correlated Neural Activity Helps Determine Ocular Dominance Column Periodicity. Trends in Neurosciences, 18 (10), 437-439. doi: 10.1016/0166-2236(95)94490-V
An Evaluation of the Use of Multidimensional-Scaling for Understanding Brain Connectivity
Goodhill, GJ, Simmen, MW and Willshaw, DJ (1995). An Evaluation of the Use of Multidimensional-Scaling for Understanding Brain Connectivity. Philosophical Transactions of the Royal Society of London Series B-Biological Sciences, 348 (1325), 265-280. doi: 10.1098/rstb.1995.0068
Elastic net model of ocular dominance - overall stripe pattern and monocular deprivation
Goodhill, G. J. and Willshaw, D. J. (1994). Elastic net model of ocular dominance - overall stripe pattern and monocular deprivation. Neural Computation, 6 (4), 615-621. doi: 10.1162/neco.1994.6.4.615
Scaling and Brain Connectivity
Simmen, MW, Goodhill, GJ and Willshaw, DJ (1994). Scaling and Brain Connectivity. Nature, 369 (6480), 448-449. doi: 10.1038/369448b0
The role of weight normalization in competitive learning
Goodhill, G. J. and Barrow, H. G. (1994). The role of weight normalization in competitive learning. Neural Computation, 6 (2), 255-269. doi: 10.1162/neco.1994.6.2.255
Scaling and brain connectivity [8]
Simmen, M. W., Goodhill, G. J., Willshaw, D. J., Young, M. P., Scannell, J. W., Burns, G. A P C and Blakemore, C. (1994). Scaling and brain connectivity [8]. Nature, 369 (6480), 448-450.
Topography and Ocular Dominance - a Model Exploring Positive Correlations
Goodhill, GJ (1993). Topography and Ocular Dominance - a Model Exploring Positive Correlations. Biological Cybernetics, 69 (2), 109-118. doi: 10.1007/BF00226194
Application of the elastic net algorithm to the formation of ocular dominance stripes
Goodhill, G. J. and Willshaw, D. J. (1990). Application of the elastic net algorithm to the formation of ocular dominance stripes. Network-Computation in Neural Systems, 1 (1), 41-59. doi: 10.1088/0954-898X/1/1/004
Sensitivity and Robustness in an Axon Guidance Signaling System
Bicknell, Brendan A., Dayan, Peter and Goodhill, Geoffrey J. (2017). Sensitivity and Robustness in an Axon Guidance Signaling System. 61st Annual Meeting of the Biophysical-Society, New Orleans La, Feb 11-15, 2017. CAMBRIDGE: CELL PRESS. doi: 10.1016/j.bpj.2016.11.752
Emergence of ion channel modal gating from independent subunit kinetics
Bicknell, Brendan A. and Goodhill, Geoffrey J. (2016). Emergence of ion channel modal gating from independent subunit kinetics. Washington, DC, United States: National Academy of Sciences. doi: 10.1073/pnas.1604090113
Segmenting neuronal growth cones using deep convolutional neural networks
Huang, Jackson Y., Hughes, Nicholas J. and Goodhill, Geoffrey J. (2016). Segmenting neuronal growth cones using deep convolutional neural networks. International Conference on Digital Image Computing - Techniques and Applications (DICTA), Gold Coast, Australia, 30 November-2 December 2016. Piscataway, NJ, United States: IEEE. doi: 10.1109/DICTA.2016.7797081
Computational models of map development in visual cortex
Goodhill, Geoff (2012). Computational models of map development in visual cortex. The Royal Australian and New Zealand College of Ophthalmologists 44th Annual Scientific Congress, Melbourne, Australia, 24-28 November 2012. Richmond, VIC., Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ceo.12011
Differential Priors for Elastic Nets
Carreira-Perpinan, M., Dayan, P. and Goodhill, G. J. (2005). Differential Priors for Elastic Nets. IDEAL 2005, Brisbane Australia, July 6-8. Berlin: Springer. doi: 10.1007/11508069_44
Limitations on detection of gradients of diffusible chemicals by axone
Urbach, JS and Goodhill, GJ (1999). Limitations on detection of gradients of diffusible chemicals by axone. 7th Annual Computational Neuroscience Meeting (CNS 98), Santa Barbara Ca, Jul, 1998. AMSTERDAM: ELSEVIER SCIENCE BV.
A mathematical model of axon guidance by diffusible factors
Goodhill, GJ (1998). A mathematical model of axon guidance by diffusible factors. 11th Annual Conference on Neural Information Processing Systems (NIPS), Denver Co, Dec 01-06, 1997. CAMBRIDGE: M I T PRESS.
Gradients for retinotectal mapping
Goodhill, Geoffrey J. (1998). Gradients for retinotectal mapping. 11th Annual Conference on Neural Information Processing Systems, NIPS 1997, , , December 1, 1997-December 6, 1997. Neural information processing systems foundation.
Objective functions for topography: A comparison of optimal maps
Goodhill, GJ and Sejnowski, TJ (1997). Objective functions for topography: A comparison of optimal maps. 4th Neural Computation and Psychology Workshop (NCPW4), London England, Apr 09-11, 1997. GODALMING: SPRINGER-VERLAG LONDON LTD.
Goodhill, GJ, Finch, S and Sejnowski, TJ (1996). Optimizing cortical mappings. 9th Annual Conference on Neural Information Processing Systems (NIPS), Denver Co, Nov 27-30, 1995. CAMBRIDGE: M I T PRESS.
Quantifying neighbourhood preservation in topographic mappings
Goodhill, G.J. and Sejnowski, T.J. (1996). Quantifying neighbourhood preservation in topographic mappings. 3rd Joint Symposium on Neural Computation, La Jolla, CA United States, 1 June 1996. La Jolla, CA United States: University of California.
A Neural Computation - Spatial to Temporal Transformation
Zamoraramos, C and Goodhill, GJ (1994). A Neural Computation - Spatial to Temporal Transformation. Satellite Workshop on Information Processing Underlying Gaze Control, at the 16th European-Neuroscience-Association Meeting, Seville Spain, Sep 22-24, 1993. OXFORD: PERGAMON PRESS LTD.
Dayan, P and Goodhill, G (1992). Perturbing Hebbian Rules. 5Th Conf On Neural Information Processing Systems - Natural and Synthetic ( Nips-91 ), Denver Co, Dec 02-05, 1991. SAN MATEO: MORGAN KAUFMANN PUB INC.
Topography and Ocular Dominance Can Arise From Distributed Patterns of Activity
Goodhill, G (1991). Topography and Ocular Dominance Can Arise From Distributed Patterns of Activity. International Joint Conf On Neural Networks ( Ijcnn-91-Seattle ), Seattle Wa, Jul 08-12, 1991. NEW YORK: I E E E.
LEARNING REPRESENTATIONS BY RECIRCULATION
Hinton, Geoffrey E., McClelland, James L. and Goodhill, Geoffrey J. (1987). LEARNING REPRESENTATIONS BY RECIRCULATION. 1987 IEEE Conference on Neural Information Processing Systems - Natural and Synthetic., , , IEEE.
Zebrafish Behavioural Feeding Assay Old Data
Goodhill, Geoffrey (2020). Zebrafish Behavioural Feeding Assay Old Data. The University of Queensland. (Dataset) doi: 10.48610/8b5b1b7
Zebrafish feeding assay behavioural analysis
Goodhill, Geoffrey (2019). Zebrafish feeding assay behavioural analysis. The University of Queensland. (Dataset) doi: 10.48610/4565690
Zebrafish model of Fragile X syndrome neural imaging
Goodhill, Geoffreyg (2019). Zebrafish model of Fragile X syndrome neural imaging. The University of Queensland. (Dataset) doi: 10.48610/5e9ea88
Neural decoding of visual information in the zebrafish
Goodhill, Geoffrey (2018). Neural decoding of visual information in the zebrafish. The University of Queensland. (Dataset) doi: 10.48610/6b5bfe1
How does environmental enrichment affect brain development?
(2021–2023) ARC Discovery Projects
Mapping neurodevelopmental disorders in a zebrafish model
(2021) NHMRC Investigator Grants
(2020–2023) Breast Cancer Research Program
How do patterns of brain activity emerge during early life?
(2020–2022) ARC Discovery Projects
Role of spontaneous activity in the formation of functional cortical circuits in vivo
(2019–2022) NHMRC Project Grant
Histology and Advanced Microscopy Research Facility upgrade
(2019) UQ Major Equipment and Infrastructure
Neural circuit development in the Fragile X zebrafish
(2018–2020) Simons Foundation Autism Research Initiative
Spontaneous activity and neural decoding in the developing brain
(2018–2020) ARC Discovery Projects
Advanced statistical methods for analysing maps in the visual brain
(2017–2019) ARC Discovery Projects
Lattice light sheet microscopy for imaging biology in real space and time
(2017) ARC Linkage Infrastructure, Equipment and Facilities
How are axons guided to their targets in the developing nervous system?
(2016–2018) NHMRC Project Grant
Light-sheet microscope for high-speed 3D imaging of live organisms and fixed tissue
(2016) NHMRC Equipment Grant
Computational analysis of the influence of growth cone shape dynamics on axon guidance
(2015–2018) NHMRC Project Grant
The plasticity of neural codes
(2015–2017) ARC Discovery Projects
(2015) UQ Major Equipment and Infrastructure
Two-photon microscopy for live and fixed imaging in model organisms and thick tissue
(2014) UQ Major Equipment and Infrastructure
(2013–2015) NHMRC Project Grant
(2013–2014) ARC Linkage Infrastructure, Equipment and Facilities
Spinning disk confocal for advanced high-speed histocytometry and neuromorphology analysis
(2013) UQ Major Equipment and Infrastructure
Mechanisms of nerve fibre guidance by molecular gradients
(2011–2013) ARC Discovery Projects
Cyclic-nucleotide-dependent regulation of axon guidance sensitivity
(2010–2012) NHMRC Project Grant
(2010) NHMRC Equipment Grant
(2009–2011) Australian National University
(2008–2012) Human Frontier Science Program Organisation
A new theory for retinotectal map formation
(2008–2010) ARC Discovery Projects
The dynamics of gradient sensing by growth cones: timelapse imaging and mathematical modelling
(2007–2009) NHMRC Project Grant
Thinking Systems: Navigating Through Real and Conceptual Spaces
(2006–2011) ARC Special Initiative
Wiring up the nervous system: how do axons detect molecular gradients?
(2006–2008) ARC Discovery Projects
Advanced Cell Labelling and Imaging Facility
(2006) ARC Linkage Infrastructure, Equipment and Facilities
CRCNS: Mechanisms of axonal gradient detection
(2005) Georgetown University
CRCNS: Spontaneous activity, lateral interactions and cortical maps
(2004–2007) University of Pennsylvania
Information processing in the developing zebrafish brain
(2020) Doctor Philosophy — Principal Advisor
Other advisors:
Neural encoding models for multivariate optical imaging data
(2020) Doctor Philosophy — Principal Advisor
Other advisors:
Investigating the links between spontaneous activity and behaviour in the zebrafish optic tectum
(2018) Master Philosophy — Principal Advisor
Neural correlates of visual function in agenesis of the corpus callosum
(2018) Doctor Philosophy — Principal Advisor
Other advisors:
Noise and sensitivity in cell signalling
(2018) Doctor Philosophy — Principal Advisor
Mathematical Modelling of Axon Guidance in Chemical Gradients
(2016) Doctor Philosophy — Principal Advisor
Neural Plasticity via Visual Cortical Maps
(2016) Doctor Philosophy — Principal Advisor
In vivo imaging of the zebrafish retinotectal map
(2015) Doctor Philosophy — Principal Advisor
Other advisors:
Mechanisms of Axon Guidance by Gradients
(2013) Doctor Philosophy — Principal Advisor
Mechanisms of cerebral cortical development
(2012) Doctor Philosophy — Principal Advisor
The development of retinotectal maps
(2012) Doctor Philosophy — Principal Advisor
Natural scene statistics and the development of the primary visual cortex
(2011) Doctor Philosophy — Principal Advisor
Other advisors:
A Bayesian Model of Axon Guidance
(2009) Doctor Philosophy — Principal Advisor
Contralateral targeting of the corpus callosum
(2017) Doctor Philosophy — Associate Advisor
Functional investigation of neural circuits in larval zebrafish
(2016) Doctor Philosophy — Associate Advisor
Other advisors:
Neocortical area patterning and the targeting of callosal axons in the contralateral hemisphere
(2013) Doctor Philosophy — Associate Advisor
Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.