The University of Queensland

Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically ill

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey eds. (2017). Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically ill. Gateway East, Singapore: Springer Singapore. doi: 10.1007/978-981-10-5336-8

Drug dosing in obesity: antimicrobials

Syed Tabish R. Zaidi and Jason A. Roberts eds. (2016). Drug dosing in obesity: antimicrobials. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-44034-7

Pharmacology

Kirk, Christa Jefferis, Abdul-Aziz, Mohd H., Roberts, Jason A., Valencia, Eleonore, Watt, Kevin, MacLaren, Graeme and Shekar, Kiran (2022). Pharmacology. Extracorporeal life support: The ELSO red book. (pp. 643-654) edited by Graeme Maclaren, Daniel Brodie, Roberto Lorusso, Giles Peek, Ravi Thiagarajan and Leen Vercaemst. Ann Arbor, MI, United States: Extracorporeal Life Support Organization.

PK/PD and the drug delivery regimen for infusion in the critical care setting

Sime, Fekade B. and Roberts, Jason A. (2021). PK/PD and the drug delivery regimen for infusion in the critical care setting. Drug delivery approaches: perspectives from pharmacokinetics and pharmacodynamics. (pp. 355-374) edited by Bret Berner, Toufigh Gordi, Heather A. E. Benson and Michael S.Roberts. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781119772767.ch10

Clinical pharmacy considerations in ICU

Jamal, Janattul-Ain, Abdul-Aziz, Mohd-Hafiz, Levkovich, Bianca and Roberts, Jason A. (2019). Clinical pharmacy considerations in ICU. Encyclopedia of pharmacy practice and clinical pharmacy. (pp. 849-865) edited by Zaheer-Ud-Din Babar. Oxford, United Kingdom: Elsevier. doi: 10.1016/B978-0-12-812735-3.00576-8

Advanced clinical pharmacy practitioner

Sokn, Erick, Calabrese, Sam, Scheckelhoff, Douglas, Thomas, Dixon and Roberts, Jason A. (2018). Advanced clinical pharmacy practitioner. Clinical Pharmacy Education, Practice and Research: Clinical Pharmacy, Drug Information, Pharmacovigilance, Pharmacoeconomics and Clinical Research. (pp. 465-472) London, United Kingdom: Elsevier. doi: 10.1016/B978-0-12-814276-9.00033-7

Antibiotic dosing during extracorporeal membrane oxygenation

Abdul-Aziz, M. H., Shekar, Kiran and Roberts, Jason A. (2018). Antibiotic dosing during extracorporeal membrane oxygenation. Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill. (pp. 151-171) edited by Andrew A. Udy, Jason A. Roberts and Jeffrey Lipman. Gateway East, Singapore: Springer . doi: 10.1007/978-981-10-5336-8_8

Antibiotic pharmacodynamics

Sime, Fekade B. and Roberts, Jason A. (2018). Antibiotic pharmacodynamics. Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically ill. (pp. 17-29) edited by Andrew Udy, Jason A. Roberts and Jeffrey Lipman. Singapore, Singapore: Springer Nature. doi: 10.1007/978-981-10-5336-8_2

Appropriate antimicrobial therapy in critically ill patients

Sime, Fekade B. and Roberts, Jason A. (2018). Appropriate antimicrobial therapy in critically ill patients. Abdominal Sepsis: a multidisciplinary approach. (pp. 319-342) edited by Massimo Sartelli, Matteo Bassetti and Ignacio Martin-Loeches. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-59704-1_21

Preface

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2018). Preface. Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically Ill. (pp. v-vii) edited by Andrew A. Udy, Jason A. Roberts and Jeffrey Lipman. Singapore, Singapore: Springer Singapore.

Ampicillin and amoxicillin

Geddes, Alasdair M., Gould, Ian M., Roberts, Jason A., Lindsay Grayson, M. and Cosgrove, Sara E. (2017). Ampicillin and amoxicillin. Kucers’ the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 100-135) edited by M. Lindsay Grayson, Sara E. Cosgrove, Suzanne Crowe, William Hope, James S. McCarthy, John Mills, Johan W. Mouton and David L. Paterson. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110

Benzylpenicillin (penicillin G)

Geddes, Alasdair M., Gould, Ian M., Roberts, Jason A., Trubiano, Jason A. and Lindsay Grayson, M. (2017). Benzylpenicillin (penicillin G). Kucers’ the use of antibiotics: a clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 23-91) edited by M. Lindsay Grayson, Sara E. Cosgrove, Suzanne Crowe, William Hope, James S. McCarthy, John Mills, Johan W. Mouton and David L. Paterson. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110

Cephalothin and cefazolin

Denny, Kerina J., Lipman, Jeffrey and Roberts, Jason A. (2017). Cephalothin and cefazolin. Kucers the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 347-360) Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110

Pharmacokinetic and pharmacodynamic tools to increase efficacy

Sinnollareddy, Mahipal G., Cotta, Menino O. and Roberts, Jason A. (2017). Pharmacokinetic and pharmacodynamic tools to increase efficacy. Antimicrobial stewardship. (pp. 85-98) edited by Celine Pulcini, Önder Ergönül, Füsun Can and Bojana Beović. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-810477-4.00007-6

Phenoxypenicillins

Geddes, Alasdair M., Gould, Ian M. and Roberts, Jason A. (2017). Phenoxypenicillins. Kucers’ the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 92-99) edited by M. Lindsay Grayson, Sara E. Cosgrove, Suzanne Crowe, William Hope, James S. McCarthy, John Mills, Johan W. Mouton and David L. Paterson. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110

Aminoglycoside dosing in obesity

Jamal, Janattul-Ain and Roberts, Jason A. (2016). Aminoglycoside dosing in obesity. Drug Dosing in Obesity: Volume I: Antimicrobials. (pp. 39-44) edited by Syed Tabish R. Zaidi and Jason A. Roberts. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-44034-7_4

Isolation and characterization of poliovirus in cell culture systems

Thorley, Bruce R. and Roberts, Jason A. (2016). Isolation and characterization of poliovirus in cell culture systems. Poliovirus: methods and protocols. (pp. 29-53) edited by Javier Martin. New York, United States: Humana Press. doi: 10.1007/978-1-4939-3292-4_4

Pharmacodynamic considerations in critically ill patients

Sinnollareddy, Mahipal G. and Roberts, Jason A. (2016). Pharmacodynamic considerations in critically ill patients. Antibiotic pharmacodynamics. (pp. 537-560) edited by John C. Rotschafer, David R. Andes and Keith A. Rodvold. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-3323-5_21

Pharmacokinetic and pharmacodynamic principles of antimicrobials

Osbert Cotta, Menino and Roberts, Jason (2016). Pharmacokinetic and pharmacodynamic principles of antimicrobials. Antimicrobial stewardship. (pp. 71-78) edited by Matthew Laundy, Mark Gilchrist and Laura Whitney. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/med/9780198758792.003.0009

Polyene antifungals

Jamal, Janattul-Ain and Roberts, Jason A. (2016). Polyene antifungals. Drug Dosing in Obesity: Volume I: Antimicrobials. (pp. 109-115) edited by Syed Tabish R. Zaidi and Jason A. Roberts. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-44034-7_10

How do I adjust antimicrobial daily dosage in patients with MODS? a pharmacist’s contribution

Ulldemolins, Marta and Roberts, Jason A. (2012). How do I adjust antimicrobial daily dosage in patients with MODS? a pharmacist’s contribution. Sepsis management: PIRO and MODS. (pp. 199-216) edited by Jordi Rello, Jeffrey Lipman and Thiago Lisboa. Berlin, Germany: Springer.

Antibiotic dosing in critically ill patients

Ulldemolins, Marta, Roberts, Jason, Varghese, Julie and Lipman, Jeffrey (2010). Antibiotic dosing in critically ill patients. Critical Care Update 2009. (pp. 128-142) edited by Vineet Nayar, J. V. Peter, Roop Kishen and S. Srinivas. Daryaganj, New Delhi, India: Jaypee Brothers Medical Publishers.

Augmented renal clearance: Unraveling the mystery of elevated antibiotic clearance

Udy, Andrew, Roberts, Jason and Lipman, Jeffrey (2010). Augmented renal clearance: Unraveling the mystery of elevated antibiotic clearance. Yearbook of Intensive Care and Emergency Medicine 2010. (pp. 495-506) edited by J.-L. Vincent. Brussels, Belgium: Springer Verlag. doi: 10.1007/978-3-642-10286-8

Drug distribution: is it a more important determinant of drug dosing than clearance?

Ulldemolins, M., Roberts, J. A. and Rello, J. (2010). Drug distribution: is it a more important determinant of drug dosing than clearance?. Intensive care medicine: annual update 2010. (pp. 507-516) Brussels, Belgium: Springer. doi: 10.1007/978-1-4419-5562-3_47

Avoiding toxicity of antibiotics

Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2009). Avoiding toxicity of antibiotics. Patient safety and quality of care in intensive care medicine. (pp. 291-304) edited by Jean-Daniel Chiche and Leanne M. Aitken. Berlin, Germany: Medizinisch Wissenschaftliche Verlagsgesellschaft.

Dose adjustment and pharmacodynamic considerations for antibiotics in severe sepsis and septic Shock

Udy, Andrew, Roberts, Jason, Boots, Robert and Lipman, Jeffrey (2008). Dose adjustment and pharmacodynamic considerations for antibiotics in severe sepsis and septic Shock. Sepsis: New Strategies for Management. (pp. 97-136) Berlin, Heidelberg: Springer Berlin Heidelberg. doi: 10.1007/978-3-540-79001-3_8

Dose adjustment and pharmacodynamic considerations for antibiotics in severe sepsis and septic shock

Udy, Andrew, Roberts, Jason A., Boots, Robert J. and Lipman, Jeffrey (2008). Dose adjustment and pharmacodynamic considerations for antibiotics in severe sepsis and septic shock. Sepsis: New strategies for management. (pp. 97-102) edited by Jordi Rello and Marcos I. Restrepo. London: Springer-Verlag. doi: 10.1007/978-3-540-79001-3

Dose adjustment and pharmacokinetics of antibiotics in severe sepsis and septic shock

Roberts, J. A. and Lipman, J. (2007). Dose adjustment and pharmacokinetics of antibiotics in severe sepsis and septic shock. Infectious diseases in critical care. (pp. 122-146) edited by Jordi Rello, Marin Kollef, Emili Diaz and Alejandro Rodriguez. Berlin, Germany; New York, U.S.A.: Springer. doi: 10.1007/978-3-540-34406-3_12

Comment: Is off-label medication use in the ICU a problem?

Cotta, Menino O., Roberts, Jason A. and Reade, Michael C. (2023). Comment: Is off-label medication use in the ICU a problem?. Critical Care, 27 (1) 288. doi: 10.1186/s13054-023-04546-y

International survey of antibiotic dosing and monitoring in adult intensive care units

Williams, Paul G., Tabah, Alexis, Cotta, Menino Osbert, Sandaradura, Indy, Kanji, Salmaan, Scheetz, Marc H., Imani, Sahand, Elhadi, Muhammed, Luque-Pardos, Sònia, Schellack, Natalie, Sanches, Cristina, Timsit, Jean-Francois, Xie, Jiao, Farkas, Andras, Wilks, Kathryn, Roberts, Jason A., Brinkmann, Alexander, Ramanan, Mahesh, Koulenti, Despoina, Gurjar, Mohan, Sulaiman, Helmi, Shrestha, Gentle, Cortegiani, Andrea, Crespo, Monica, Ling, Lowell, Abidi, Khalid and Schellongowski, Peter (2023). International survey of antibiotic dosing and monitoring in adult intensive care units. Critical Care, 27 (1) 241. doi: 10.1186/s13054-023-04527-1

An in vitro dynamic bioreactor model for evaluating antimicrobial effectiveness on periodontal polymicrobial biofilms: a proof-of-concept study

Ramachandra, Srinivas Sulugodu, Sime, Fekade Bruck, Naicker, Saiyuri, Han, Pingping, Lee, Ryan S.B., Wallis, Steven C., Roberts, Jason A. and Ivanovski, Sašo (2023). An in vitro dynamic bioreactor model for evaluating antimicrobial effectiveness on periodontal polymicrobial biofilms: a proof-of-concept study. Journal of Periodontology. doi: 10.1002/JPER.23-0086

Efficiency of dosing software using Bayesian forecasting in achieving target antibiotic exposures in critically ill patients, a prospective cohort study

Chai, Ming G., Roberts, Jason A., Kelly, Christina F., Ungerer, Jacobus P.J., McWhinney, Brett C., Lipman, Jeffrey, Farkas, Andras and Cotta, Menino O. (2023). Efficiency of dosing software using Bayesian forecasting in achieving target antibiotic exposures in critically ill patients, a prospective cohort study. Anaesthesia Critical Care and Pain Medicine 101296, 101296. doi: 10.1016/j.accpm.2023.101296

International consensus recommendations for the use of prolonged‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists

Hong, Lisa T., Downes, Kevin J., FakhriRavari, Alireza, Abdul‐Mutakabbir, Jacinda C., Kuti, Joseph L., Jorgensen, Sarah, Young, David C., Alshaer, Mohammad H., Bassetti, Matteo, Bonomo, Robert A., Gilchrist, Mark, Jang, Soo Min, Lodise, Thomas, Roberts, Jason A., Tängdén, Thomas, Zuppa, Athena and Scheetz, Marc H. (2023). International consensus recommendations for the use of prolonged‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 43 (8), 740-777. doi: 10.1002/phar.2842

International consensus recommendations for the use of prolonged‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists: An executive summary

Hong, Lisa T., Downes, Kevin J., FakhriRavari, Alireza, Abdul‐Mutakabbir, Jacinda C., Kuti, Joseph L., Jorgensen, Sarah, Young, David C., Alshaer, Mohammad H., Bassetti, Matteo, Bonomo, Robert A., Gilchrist, Mark, Jang, Soo Min, Lodise, Thomas, Roberts, Jason A., Tängdén, Thomas, Zuppa, Athena and Scheetz, Marc H. (2023). International consensus recommendations for the use of prolonged‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists: An executive summary. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 43 (8), 736-739. doi: 10.1002/phar.2844

Optimal drug therapy for Staphylococcus aureus bacteraemia in adults

Legg, Amy, Davis, Joshua S. and Roberts, Jason A. (2023). Optimal drug therapy for Staphylococcus aureus bacteraemia in adults. Current Opinion in Critical Care, 29 (5), 446-456. doi: 10.1097/mcc.0000000000001072

Longer term mortality and kidney outcomes of participants in the Combination Antibiotics for Methicillin Resistant <i>Staphylococcus aureus</i> (CAMERA2) trial: a <i>post-hoc</i> analysis

Legg, Amy, Roberts, Matthew A, Davies, Jane, Cass, Alan, Meagher, Niamh, Sud, Archana, Daitch, Vered, Dishon-Benattar, Yael, Yahav, Dafna, Paul, Mical, Xinxin, Chen, He Ping, Yeo, Lye, David, Lee, Russel, Robinson, J Owen, Foo, Hong, Tramontana, Adrian R, Bak, Narin, Grenfell, Adelaide, Rogers, Benjamin, Li, Ying, Joshi, Neela, O’Sullivan, Matthew, McKew, Genevieve, Ghosh, Niladri, Schneider, Kellie, Holmes, Natasha E, Dotel, Ravindra, Chia, Timothy ... the CAMERA2 study group (2023). Longer term mortality and kidney outcomes of participants in the Combination Antibiotics for Methicillin Resistant Staphylococcus aureus (CAMERA2) trial: a post-hoc analysis. Open Forum Infectious Diseases, 10 (7) ofad337. doi: 10.1093/ofid/ofad337

AUC-based monitoring and model-informed precision dosing of vancomycin in critically ill patients: why and how?

Goutelle, Sylvain, Wallet, Florent, Thoma, Yann, Peclard, Jean-Rémi, Bourguignon, Laurent, Cohen, Sabine, Kipnis, Eric, Roberts, Jason, Allaouchiche, Bernard and Friggeri, Arnaud (2023). AUC-based monitoring and model-informed precision dosing of vancomycin in critically ill patients: why and how?. Anaesthesia Critical Care & Pain Medicine, 42 (6) 101286, 101286. doi: 10.1016/j.accpm.2023.101286

In Vitro Susceptibility Testing of Imipenem- Relebactam and Tedizolid against 102 Mycobacterium abscessus isolates

Burke, Andrew, Carter, Robyn, Tolson, Carla, Congdon, Jacob, Duplancic, Christine, Bursle, Evan, Bell, Scott C, Roberts, Jason A. and Thomson, Rachel (2023). In Vitro Susceptibility Testing of Imipenem- Relebactam and Tedizolid against 102 Mycobacterium abscessus isolates. International Journal of Antimicrobial Agents, 62 (4) 106938, 106938. doi: 10.1016/j.ijantimicag.2023.106938

Validating a novel three-times-weekly post-hemodialysis ceftriaxone regimen in infected Indigenous Australian patients—a population pharmacokinetic study

Tsai, Danny, Zam, Betty B, Tongs, Carleigh, Chiong, Fabian, Sajiv, Cherian, Pawar, Basant, Ashok, Aadith, Cooper, Brynley P, Tong, Steven Y C, Janson, Sonja, Wallis, Steven C, Roberts, Jason A and Parker, Suzanne L (2023). Validating a novel three-times-weekly post-hemodialysis ceftriaxone regimen in infected Indigenous Australian patients—a population pharmacokinetic study. Journal of Antimicrobial Chemotherapy, 78 (8), 1963-1973. doi: 10.1093/jac/dkad190

Antifungal dosing in critically ill patients on extracorporeal membrane oxygenation

Lyster, Haifa, Shekar, Kiran, Watt, Kevin, Reed, Anna, Roberts, Jason A. and Abdul-Aziz, Mohd-Hafiz (2023). Antifungal dosing in critically ill patients on extracorporeal membrane oxygenation. Clinical Pharmacokinetics, 62 (7), 931-942. doi: 10.1007/s40262-023-01264-0

Is the pharmacokinetics of first-line anti-TB drugs a cause of high mortality rates in TB patients admitted to the ICU? A non-compartmental pharmacokinetic analysis

Beraldi-Magalhaes, Francisco, Parker, Suzanne L., Sanches, Cristina, Garcia, Leandro Sousa, Souza Carvalho, Brenda Karoline, Costa, Amanda Araujo, Fachi, Mariana Millan, de Liz, Marcus Vinicius, de Souza, Alexandra Brito, Safe, Izabella Picinin, Pontarolo, Roberto, Wallis, Steven, Lipman, Jeffrey, Roberts, Jason A. and Cordeiro-Santos, Marcelo (2023). Is the pharmacokinetics of first-line anti-TB drugs a cause of high mortality rates in TB patients admitted to the ICU? A non-compartmental pharmacokinetic analysis. Tropical Medicine and Infectious Disease, 8 (6) 312, 1-10. doi: 10.3390/tropicalmed8060312

Stability of nafamostat in intravenous infusion solutions, human whole blood and extracted plasma: implications for clinical effectiveness studies

Hernández-Mitre, María Patricia, Won, Hayoung, Wallis, Steven C, Parker, Suzanne L and Roberts, Jason A (2023). Stability of nafamostat in intravenous infusion solutions, human whole blood and extracted plasma: implications for clinical effectiveness studies. Bioanalysis, 673-681. doi: 10.4155/bio-2023-0040

A three-level model for therapeutic drug monitoring of antimicrobials at the site of infection

Brasier, Noé, Ates, H Ceren, Sempionatto, Juliane R., Cotta, Menino O., Widmer, Andreas F., Eckstein, Jens, Goldhahn, Jörg, Roberts, Jason A., Gao, Wei and Dincer, Can (2023). A three-level model for therapeutic drug monitoring of antimicrobials at the site of infection. The Lancet Infectious Diseases. doi: 10.1016/s1473-3099(23)00215-3

Ampicillin and ceftobiprole combination for the treatment of Enterococcus faecalis invasive infections: “The times they are a-changin”

Giuliano, Simone, Angelini, Jacopo, D’Elia, Denise, Geminiani, Monica, Barison, Roberto Daniele, Giacinta, Alessandro, Sartor, Assunta, Campanile, Floriana, Curcio, Francesco, Cotta, Menino Osbert, Roberts, Jason A., Baraldo, Massimo and Tascini, Carlo (2023). Ampicillin and ceftobiprole combination for the treatment of Enterococcus faecalis invasive infections: “The times they are a-changin”. Antibiotics, 12 (5) 879, 1-12. doi: 10.3390/antibiotics12050879

Beta-lactam dose optimisation in the intensive care unit: targets, therapeutic drug monitoring and toxicity

Legg, Amy, Carmichael, Sinead, Chai, Ming G., Roberts, Jason A. and Cotta, Menino O. (2023). Beta-lactam dose optimisation in the intensive care unit: targets, therapeutic drug monitoring and toxicity. Antibiotics, 12 (5) 870, 1-14. doi: 10.3390/antibiotics12050870

In silico evaluation of a vancomycin dosing guideline among adults with serious infections

Williams, Paul, Cotta, Menino Osbert, Abdul-Aziz, Mohd H., Wilks, Kathryn, Farkas, Andras and Roberts, Jason A (2023). In silico evaluation of a vancomycin dosing guideline among adults with serious infections. Therapeutic Drug Monitoring, Publish Ahead of Print (5), 631-636. doi: 10.1097/FTD.0000000000001102

A systematic review on antimicrobial pharmacokinetic differences between Asian and non-Asian adult populations

Setiawan, Eko, Cotta, Menino Osbert, Roberts, Jason A. and Abdul-Aziz, Mohd Hafiz (2023). A systematic review on antimicrobial pharmacokinetic differences between Asian and non-Asian adult populations. Antibiotics, 12 (5) 803, 1-23. doi: 10.3390/antibiotics12050803

Clearance of piperacillin-tazobactam and vancomycin during continuous renal replacement with regional citrate anticoagulation

Sharrock, Lucy, Ankravs, Melissa J., Deane, Adam M., Rechnitzer, Thomas, Wallis, Steven C., Roberts, Jason A. and Bellomo, Rinaldo (2023). Clearance of piperacillin-tazobactam and vancomycin during continuous renal replacement with regional citrate anticoagulation. Therapeutic Drug Monitoring, 45 (2), 265-268. doi: 10.1097/FTD.0000000000001028

Imipenem/cilastatin/relebactam efficacy, safety and probability of target attainment in adults with hospital-acquired or ventilator-associated bacterial pneumonia among patients with baseline renal impairment, normal renal function, and augmented renal clearance

Roberts, Jason A., Nicolau, David P., Martin-Loeches, Ignacio, Deryke, C Andrew, Losada, Maria C., Du, Jiejun, Patel, Munjal, Rizk, Matthew L., Paschke, Amanda and Chen, Luke F. (2023). Imipenem/cilastatin/relebactam efficacy, safety and probability of target attainment in adults with hospital-acquired or ventilator-associated bacterial pneumonia among patients with baseline renal impairment, normal renal function, and augmented renal clearance. JAC-Antimicrobial Resistance, 5 (2) dlad011, 1-12. doi: 10.1093/jacamr/dlad011

Why is the implementation of beta-lactam therapeutic drug monitoring for the critically ill falling short? A multicenter mixed-methods study

Barreto, Erin F., Chitre, Pooja N., Pine, Kathleen H., Shepel, Kathryn K., Rule, Andrew D., Alshaer, Mohammad H., Abdul Aziz, Mohd Hafiz, Roberts, Jason A., Scheetz, Marc H., Ausman, Sara E., Moreland-Head, Lindsay N., Rivera, Christina G., Jannetto, Paul J., Mara, Kristin C. and Boehmer, Kasey R. (2023). Why is the implementation of beta-lactam therapeutic drug monitoring for the critically ill falling short? A multicenter mixed-methods study. Therapeutic Drug Monitoring, Publish Ahead of Print (4), 508-518. doi: 10.1097/FTD.0000000000001059

Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients

Adiraju, Santosh K. S., Sumi, Chandra D., Pandey, Saurabh, Cotta, Menino O., Roberts, Jason A, Lipman, Jeffrey, Wallis, Steven C. and Parker, Suzanne L. (2023). Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients. Bioanalysis, 15 (1), 31-42. doi: 10.4155/bio-2022-0230

Continuous infusion of beta-lactam antibiotics: narrative review of systematic reviews, and implications for outpatient parenteral antibiotic therapy

Roberts, Jason A., Croom, Katherine and Adomakoh, Nicholas (2023). Continuous infusion of beta-lactam antibiotics: narrative review of systematic reviews, and implications for outpatient parenteral antibiotic therapy. Expert Review of Anti-infective Therapy, 21 (4), 375-385. doi: 10.1080/14787210.2023.2184347

A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study

Roberts, Jason A., Sime, Fekade, Lipman, Jeffrey, Hernández-Mitre, Maria Patricia, Baptista, João Pedro, Brüggemann, Roger J., Darvall, Jai, De Waele, Jan J., Dimopoulos, George, Lefrant, Jean-Yves, Mat Nor, Mohd Basri, Rello, Jordi, Seoane, Leonardo, Slavin, Monica A., Valkonen, Miia, Venditti, Mario, Wong, Wai Tat, Zeitlinger, Markus and Roger, Claire (2023). A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study. Critical Care and Resuscitation, 25 (1), 1-5. doi: 10.1016/j.ccrj.2023.04.002

Corrigendum to “Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis” [Crit Care Resusc 23(3) (2021) 273–284]

Billot, Laurent, Lipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino Osbert, Davis, Joshua S., Finfer, Simon, Hammond, Naomi, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Roger, Claire, Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman and Dulhunty, Joel M. (2023). Corrigendum to “Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis” [Crit Care Resusc 23(3) (2021) 273–284]. Critical Care and Resuscitation, 25 (1), 60. doi: 10.1016/j.ccrj.2023.04.012

Variable sequestration of antifungals in an extracorporeal membrane oxygenation circuit

Lyster, Haifa, Pitt, Timothy, Maunz, Olaf, Diamond, Suzanne, Roberts, Jason A., Brown, David, Mills, Jeremy, Armstrong-James, Darius, Gerovasili, Vicky, Carby, Martin, Dunning, John, Simon, Andre and Reed, Anna (2023). Variable sequestration of antifungals in an extracorporeal membrane oxygenation circuit. ASAIO Journal, 69 (3), 309-314. doi: 10.1097/mat.0000000000001802

Population pharmacokinetics and dosing simulations of ampicillin and sulbactam in hospitalised adult patients

Setiawan, Eko, Cotta, Menino Osbert, Abdul-Aziz, Mohd-Hafiz, Widjanarko, Doddy, Sosilya, Hernycane, Lukas, Dwi Lily, Wallis, Steven C., Parker, Suzanne and Roberts, Jason A. (2023). Population pharmacokinetics and dosing simulations of ampicillin and sulbactam in hospitalised adult patients. Clinical Pharmacokinetics, 62 (4), 1-14. doi: 10.1007/s40262-023-01219-5

Treatment Failure Due to Adaptive Resistance Mechanisms in a Severe and Complicated Bloodstream Infection Due to

Stewart, Adam G., Roberts, Jason A., Forde, Brian M., Bergh, Haakon, Kidd, Timothy J., Wright, Hugh and Harris, Patrick N. A. (2023). Treatment Failure Due to Adaptive Resistance Mechanisms in a Severe and Complicated Bloodstream Infection Due to . Microbial Drug Resistance, 29 (4), 145-149. doi: 10.1089/mdr.2022.0179

Population pharmacokinetic and pharmacodynamic analysis of valganciclovir for optimizing preemptive therapy of cytomegalovirus infections in kidney transplant recipients

Cojutti, Pier Giorgio, Heffernan, Aaron J., Tängdén, Thomas, Della Siega, Paola, Tascini, Carlo, Roberts, Jason A. and Pea, Federico (2023). Population pharmacokinetic and pharmacodynamic analysis of valganciclovir for optimizing preemptive therapy of cytomegalovirus infections in kidney transplant recipients. Antimicrobial Agents and Chemotherapy, 67 (3). doi: 10.1128/aac.01665-22

Population pharmacokinetics of ganciclovir in allogeneic hematopoietic stem cell transplant patients

Selby, Philip R., Heffernan, Aaron J., Yeung, David, Warner, Morgyn S., Peake, Sandra L., Hahn, Uwe, Wallis, Steven C., Mcwhinney, Brett, Ungerer, Jacobus P. J., Shakib, Sepehr and Roberts, Jason A. (2023). Population pharmacokinetics of ganciclovir in allogeneic hematopoietic stem cell transplant patients. Antimicrobial Agents and Chemotherapy, 67 (3), 1-13. doi: 10.1128/aac.01550-22

Accuracy of a precision dosing software program for predicting antibiotic concentrations in critically ill patients

Chai, Ming G, Roberts, Jason A, Farkas, Andras and Cotta, Menino O (2023). Accuracy of a precision dosing software program for predicting antibiotic concentrations in critically ill patients. Journal of Antimicrobial Chemotherapy, 78 (2), 354-358. doi: 10.1093/jac/dkac392

Antimicrobial residual drug error in the intensive care unit; a single blinded prospective observational study

Jarrett, Paul, Keogh, Samantha, Roberts, Jason A., Wallis, Steven C. and Coyer, Fiona M. (2023). Antimicrobial residual drug error in the intensive care unit; a single blinded prospective observational study. Intensive and Critical Care Nursing, 77 103403, 103403. doi: 10.1016/j.iccn.2023.103403

Fingerprick microsampling methods can replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid, and prednisolone concentrations in adult kidney transplant patients

Scuderi, Carla, Parker, Suzanne, Jacks, Margaret, John, George T., McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Healy, Helen, Roberts, Jason and Staatz, Christine (2023). Fingerprick microsampling methods can replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid, and prednisolone concentrations in adult kidney transplant patients. Therapeutic Drug Monitoring, 45 (1), 69-78. doi: 10.1097/FTD.0000000000001024

Serum Creatinine and Tacrolimus Assessment With VAMS Finger-Prick Microsampling: A Diagnostic Test Study

Scuderi, Carla E., Parker, Suzanne L., Jacks, Margaret, John, George T., McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew J., Healy, Helen G., Roberts, Jason A. and Staatz, Christine E. (2023). Serum Creatinine and Tacrolimus Assessment With VAMS Finger-Prick Microsampling: A Diagnostic Test Study. Kidney Medicine, 5 (4) 100610, 100610. doi: 10.1016/j.xkme.2023.100610

Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae—authors’ response

Sumi, Chandra Datta, Roberts, Jason A and Sime, Fekade B (2023). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae—authors’ response. Journal of Antimicrobial Chemotherapy, 78 (3), 854-857. doi: 10.1093/jac/dkad017

Antimicrobial exposures in critically ill patients receiving extracorporeal membrane oxygenation

Shekar, Kiran, Abdul-Aziz, Mohd H, Cheng, Vesa, Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Jakob, Stephan M, Kim, Hyung-Sook, Levkovich, Bianca J, Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C, Welch, Susan A, Zacharias, David, Fraser, John F. and Roberts, Jason A (2023). Antimicrobial exposures in critically ill patients receiving extracorporeal membrane oxygenation. American Journal of Respiratory and Critical Care Medicine, 207 (6), 704-720. doi: 10.1164/rccm.202207-1393oc

Are meropenem, piperacillin, tazobactam and vancomycin sequestered onto a paediatric extracorporeal membrane oxygenation circuit? An ex vivo study

Cree, Michele, Haisz, Emma, Sumi, Chandra, Wallis, Steve, Schlapbach, Luregn, Roberts, Jason and Parker, Suzanne (2023). Are meropenem, piperacillin, tazobactam and vancomycin sequestered onto a paediatric extracorporeal membrane oxygenation circuit? An ex vivo study. Australian Critical Care, 36, S5-S6. doi: 10.1016/j.aucc.2023.07.023

Does renal replacement therapy impact the clearance of meropenem, piperacillin, tazobactam and vancomycin in a critically ill child? An ex vivo study

Cree, Michele, Schlapbach, Luregn, Sumi, Chandra, Wallis, Steve, Roberts, Jason and Parker, Suzanne (2023). Does renal replacement therapy impact the clearance of meropenem, piperacillin, tazobactam and vancomycin in a critically ill child? An ex vivo study. Australian Critical Care, 36, S4-S5. doi: 10.1016/j.aucc.2023.07.020

Oral ciprofloxacin activity against ceftriaxone-resistant Escherichia coli in an in vitro bladder infection model

Abbott, Iain J., van Gorp, Elke, Cottingham, Hugh, Macesic, Nenad, Wallis, Steven C., Roberts, Jason A., Meletiadis, Joseph and Peleg, Anton Y. (2023). Oral ciprofloxacin activity against ceftriaxone-resistant Escherichia coli in an in vitro bladder infection model. Journal of Antimicrobial Chemotherapy, 78 (2), 397-410. doi: 10.1093/jac/dkac402

In silico evaluation of a beta‐lactam dosing guideline among adults with serious infections

Williams, Paul, Cotta, Menino Osbert, Abdul‐Aziz, Mohd H., Wilks, Kathryn, Farkas, Andras and Roberts, Jason A. (2022). In silico evaluation of a beta‐lactam dosing guideline among adults with serious infections. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. doi: 10.1002/phar.2753

Current and emerging treatment options for multidrug resistant Escherichia coli urosepsis: a review

Walker, Mikaela M., Roberts, Jason A., Rogers, Benjamin A., Harris, Patrick N. A. and Sime, Fekade B. (2022). Current and emerging treatment options for multidrug resistant Escherichia coli urosepsis: a review. Antibiotics, 11 (12) 1821, 1-20. doi: 10.3390/antibiotics11121821

Optimizing antifungal prophylaxis in allogeneic stem cell transplantation: A cohort study of two different approaches

Selby, Philip R., Warner, Morgyn S., Peake, Sandra L., Bardy, Peter, Hiwase, Devendra, Singhal, Deepak, Beligaswatte, Ashanka, Hahn, Uwe, Roberts, Jason A., Yeung, David and Shakib, Sepehr (2022). Optimizing antifungal prophylaxis in allogeneic stem cell transplantation: A cohort study of two different approaches. Transplant Infectious Disease, 24 (6) e13988, 1-11. doi: 10.1111/tid.13988

Anticoagulation strategies in non–critically ill patients with Covid-19

McQuilten, Zoe K., Venkatesh, Balasubramanian, Jha, Vivekanand, Roberts, Jason, Morpeth, Susan C., Totterdell, James A., McPhee, Grace M., Abraham, John, Bam, Niraj, Bandara, Methma, Bangi, Ashpak K., Barina, Lauren A., Basnet, Bhupendra K., Bhally, Hasan, Bhusal, Khema R., Bogati, Umesh, Bowen, Asha C., Burke, Andrew J., Christopher, Devasahayam J., Chunilal, Sanjeev D., Cochrane, Belinda, Curnow, Jennifer L., Das, Santa Kumar, Dhungana, Ashesh, Di Tanna, Gian Luca, Dotel, Ravindra, DSouza, Hyjel, Dummer, Jack, Dutta, Sourabh ... Tong, Steven Y.C. (2022). Anticoagulation strategies in non–critically ill patients with Covid-19. NEJM Evidence, 2 (2). doi: 10.1056/evidoa2200293

Reply to Fillatre, et al. and Li, et al

Abdul-Aziz, Mohd H., Roberts, Jason A. and Shekar, Kiran (2022). Reply to Fillatre, et al. and Li, et al. American Journal of Respiratory and Critical Care Medicine, 207 (7), 952-953. doi: 10.1164/rccm.202211-2140LE

ASCOT ADAPT study of COVID-19 therapeutics in hospitalised patients: an international multicentre adaptive platform trial

Denholm, Justin T., Venkatesh, Balasubramanian, Davis, Joshua, Bowen, Asha C., Hammond, Naomi E., Jha, Vivekanand, McPhee, Grace, McQuilten, Zoe, O’Sullivan, Matthew V. N., Paterson, David, Price, David, Rees, Megan, Roberts, Jason, Jones, Mark, Totterdell, James, Snelling, Thomas, Trask, Nanette, Morpeth, Susan, Tong, Steven YC and on behalf of the ASCOT ADAPT investigators (2022). ASCOT ADAPT study of COVID-19 therapeutics in hospitalised patients: an international multicentre adaptive platform trial. Trials, 23 (1) 1014. doi: 10.1186/s13063-022-06929-y

Fred J Boyd Oration 2021

Roberts, Jason A. (2022). Fred J Boyd Oration 2021. Journal of Pharmacy Practice and Research, 52 (6), 482-484. doi: 10.1002/jppr.1851

Scoping review on diagnostic criteria and investigative approach in sepsis of unknown origin in critically ill patients

Ling, Lowell, Mui, Oliver Oi Yat, Laupland, Kevin B., Lefrant, Jean-Yves, Roberts, Jason A., Gopalan, Pragasan Dean, Lipman, Jeffrey, Joynt, Gavin M., Stelfox, Tom, Niven, Daniel, Paramalingam, Rameiya, Vonderhaar, Derek, Freebairn, Ross, Ling, Lowell, Leung, Patricia, Gopalan, Dean, Lefrant, Jean Yves, Lloret, Sophie, Elotmani, Loubna, Fourie, Cheryl, Saba, Renee, Carlisle, Dougal and Edwards, Felicity (2022). Scoping review on diagnostic criteria and investigative approach in sepsis of unknown origin in critically ill patients. Journal of Intensive Care, 10 (1) 44, 1-10. doi: 10.1186/s40560-022-00633-4

The Staphylococcus aureus Network Adaptive Platform trial protocol: new tools for an old foe

Tong, Steven Y. C., Mora, Jocelyn, Bowen, Asha C., Cheng, Matthew P., Daneman, Nick, Goodman, Anna L., Heriot, George S., Lee, Todd C., Lewis, Roger J., Lye, David C., Mahar, Robert K., Marsh, Julie, McGlothlin, Anna, McQuilten, Zoe, Morpeth, Susan C., Paterson, David L., Price, David J., Roberts, Jason A., Robinson, J Owen, van Hal, Sebastiaan J., Walls, Genevieve, Webb, Steve A., Whiteway, Lyn, Yahav, Dafna and Davis, Joshua S. (2022). The Staphylococcus aureus Network Adaptive Platform trial protocol: new tools for an old foe. Clinical Infectious Diseases, 75 (11), 2027-2034. doi: 10.1093/cid/ciac476

Correction to: Risk Factors for Nephrotoxicity in Methicillin-Resistant Staphylococcus aureus Bacteraemia: A Post Hoc Analysis of the CAMERA2 Trial

Legg, Amy, Meagher, Niamh, Johnson, Sandra A., Roberts, Matthew A., Cass, Alan, Scheetz, Marc H., Davies, Jane, Roberts, Jason A., Davis, Joshua S. and Tong, Steven Y. C. (2022). Correction to: Risk Factors for Nephrotoxicity in Methicillin-Resistant Staphylococcus aureus Bacteraemia: A Post Hoc Analysis of the CAMERA2 Trial. Clinical Drug Investigation, 43 (1), 35-35. doi: 10.1007/s40261-022-01224-9

Performance of different body weights in the Cockcroft‐Gault equation in critically ill patients with and without augmented renal clearance: a multicenter cohort

Cucci, Michaelia D., Gerlach, Anthony T., Mangira, Caroline, Murphy, Claire V., Roberts, Jason A., Udy, Andrew A., Dowling, Thomas C. and Mullen, Chanda L. (2022). Performance of different body weights in the Cockcroft‐Gault equation in critically ill patients with and without augmented renal clearance: a multicenter cohort. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. doi: 10.1002/phar.2743

Optimisation of treatments for oral Neisseria gonorrhoeae infection: Pharmacokinetics Study (STI-PK project) - study protocol for non-randomised clinical trial

Kong, Fabian Y. S., Unemo, Magnus, Lim, Shueh H., Latch, Ngaire, Williamson, Deborah A., Roberts, Jason A., Wallis, Steven C., Parker, Suzanne L., Landersdorfer, Cornelia B., Yap, Tami, Fairley, Christopher K., Chow, Eric P F, Lewis, David A., Hammoud, Mohamed A. and Hocking, Jane S. (2022). Optimisation of treatments for oral Neisseria gonorrhoeae infection: Pharmacokinetics Study (STI-PK project) - study protocol for non-randomised clinical trial. BMJ open, 12 (11) e064782, 1-8. doi: 10.1136/bmjopen-2022-064782

Evaluation of fosfomycin-sulbactam combination therapy against carbapenem-resistant Acinetobacter baumannii isolates in a hollow-fibre infection model

Mohd Sazlly Lim, Sazlyna, Heffernan, Aaron, Naicker, Saiyuri, Wallis, Steven, Roberts, Jason A. and Sime, Fekade Bruck (2022). Evaluation of fosfomycin-sulbactam combination therapy against carbapenem-resistant Acinetobacter baumannii isolates in a hollow-fibre infection model. Antibiotics, 11 (11) 1578, 1-11. doi: 10.3390/antibiotics11111578

Closed-loop control of continuous piperacillin delivery: an in silico study

Herrero, Pau, Wilson, Richard C., Armiger, Ryan, Roberts, Jason A., Holmes, Alison, Georgiou, Pantelis and Rawson, Timothy M. (2022). Closed-loop control of continuous piperacillin delivery: an in silico study. Frontiers in Bioengineering and Biotechnology, 10 1015389, 1-10. doi: 10.3389/fbioe.2022.1015389

Risk factors for nephrotoxicity in methicillin-resistant Staphylococcus aureus bacteraemia: a post hoc analysis of the CAMERA2 trial

Legg, Amy, Meagher, Niamh, Johnson, Sandra A., Roberts, Matthew A., Cass, Alan, Scheetz, Marc H., Davies, Jane, Roberts, Jason A., Davis, Joshua S. and Tong, Steven Y. C. (2022). Risk factors for nephrotoxicity in methicillin-resistant Staphylococcus aureus bacteraemia: a post hoc analysis of the CAMERA2 trial. Clinical Drug Investigation, 43 (1), 23-33. doi: 10.1007/s40261-022-01204-z

Optimizing meropenem in highly resistant Klebsiella pneumoniae environments: population pharmacokinetics and dosing simulations in critically ill patients

Truong, Anh Quan, Dao, Xuan Co, Vu, Dinh Hoa, Nguyen, Hoang Anh, Do, Thi Hong Gam, Tran, Nhan Thang, Tran, Nhat Minh, Vu, Ngan Binh, Pham, Hong Nhung, Bui, Van Cuong, Trinh, The Anh, Dang, Quoc Tuan, Nguyen, Gia Binh, Lipman, Jeffrey, Cotta, Menino O. and Roberts, Jason A. (2022). Optimizing meropenem in highly resistant Klebsiella pneumoniae environments: population pharmacokinetics and dosing simulations in critically ill patients. Antimicrobial Agents and Chemotherapy, 66 (11) e0032122, 1-11. doi: 10.1128/aac.00321-22

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381. doi: 10.1126/scitranslmed.abj238

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381, 1-16. doi: 10.1126/scitranslmed.abj2381

Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs

Jager, Nynke G. L., Chai, Ming G., van Hest, Reiner M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2022). Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs. Clinical Microbiology and Infection, 28 (9), 1211-1224. doi: 10.1016/j.cmi.2022.03.041

Nafamostat mesylate for treatment of COVID-19 in hospitalised patients: a structured, narrative review

Hernández-Mitre, María Patricia, Tong, Steven Y. C., Denholm, Justin T., Dore, Gregory J., Bowen, Asha C., Lewin, Sharon R., Venkatesh, Balasubramanian, Hills, Thomas E., McQuilten, Zoe, Paterson, David L., Morpeth, Susan C. and Roberts, Jason A. (2022). Nafamostat mesylate for treatment of COVID-19 in hospitalised patients: a structured, narrative review. Clinical Pharmacokinetics, 61 (10), 1331-1343. doi: 10.1007/s40262-022-01170-x

Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Escherichia coli clinical isolates

Sumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2022). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Escherichia coli clinical isolates. Journal of Antimicrobial Chemotherapy, 77 (11), 3026-3034. doi: 10.1093/jac/dkac273

Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software

Roberts, Jason A., Bellomo, Rinaldo, Cotta, Menino O., Koch, Birgit C. P., Lyster, Haifa, Ostermann, Marlies, Roger, Claire, Shekar, Kiran, Watt, Kevin and Abdul-Aziz, Mohd H. (2022). Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software. Intensive Care Medicine, 48 (10), 1338-1351. doi: 10.1007/s00134-022-06847-2

Pharmacodynamics of Piperacillin-Tazobactam/Amikacin Combination versus Meropenem against Extended-Spectrum β-Lactamase-Producing Escherichia coli in a Hollow Fiber Infection Model

Islam, Kamrul, Sime, Fekade B., Wallis, Steven C., Bauer, Michelle J., Naicker, Saiyuri, Won, Hayoung, Zowawi, Hosam M., Choudhury, Md Abu, Shirin, Tahmina, Habib, Zakir H., Harris, Patrick N. A., Flora, Meerjady S. and Roberts, Jason A. (2022). Pharmacodynamics of Piperacillin-Tazobactam/Amikacin Combination versus Meropenem against Extended-Spectrum β-Lactamase-Producing Escherichia coli in a Hollow Fiber Infection Model. Antimicrobial Agents and Chemotherapy, 66 (9), e0016222. doi: 10.1128/aac.00162-22

Pharmacodynamic evaluation of piperacillin/tazobactam against extended-spectrum β-lactamase-producing versus non-producing Escherichia coli in a hollow-fibre infection model

Islam, Kamrul, Sime, Fekade B., Bauer, Michelle J., Forde, Brian M., Wallis, Steven C., Harris, Patrick, Naicker, Saiyuri, Shirin, Tahmina, Habib, Zakir H., Flora, Meerjady S. and Roberts, Jason A. (2022). Pharmacodynamic evaluation of piperacillin/tazobactam against extended-spectrum β-lactamase-producing versus non-producing Escherichia coli in a hollow-fibre infection model. International Journal of Antimicrobial Agents, 60 (2) 106623, 1-7. doi: 10.1016/j.ijantimicag.2022.106623

Plasma and cerebrospinal fluid population pharmacokinetics of meropenem in neurocritical care patients: a prospective two-center study

Kumta, Nilesh, Heffernan, Aaron J., Cotta, Menino Osbert, Wallis, Steven C., Livermore, Amelia, Starr, Therese, Wong, Wai Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2022). Plasma and cerebrospinal fluid population pharmacokinetics of meropenem in neurocritical care patients: a prospective two-center study. Antimicrobial Agents and Chemotherapy, 66 (8) e0014222, 1-12. doi: 10.1128/aac.00142-22

Plasma and interstitial fluid pharmacokinetics of prophylactic cefazolin in elective bariatric surgery patients

Ryan, Rochelle L., Jackson, Dwane, Hopkins, George, Eley, Victoria, Christensen, Rebecca, Van Zundert, Andre A. J., Wallis, Steven C., Lipman, Jeffrey, Parker, Suzanne L. and Roberts, Jason A. (2022). Plasma and interstitial fluid pharmacokinetics of prophylactic cefazolin in elective bariatric surgery patients. Antimicrobial Agents and Chemotherapy, 66 (7), e0041922. doi: 10.1128/aac.00419-22

Pharmacodynamic evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum β-lactamase-producing and non-producing Escherichia coli clinical isolates in a hollow-fibre infection model

Islam, Kamrul, Sime, Fekade B., Wallis, Steven C., Bauer, Michelle J., Forde, Brian M., Harris, Patrick, Shirin, Tahmina, Habib, Zakir H., Flora, Meerjady S. and Roberts, Jason A. (2022). Pharmacodynamic evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum β-lactamase-producing and non-producing Escherichia coli clinical isolates in a hollow-fibre infection model. Journal of Antimicrobial Chemotherapy, 77 (9), 2448-2455. doi: 10.1093/jac/dkac186

Optimal dosing of cefotaxime and desacetylcefotaxime for critically ill paediatric patients. Can we use microsampling?

Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2022). Optimal dosing of cefotaxime and desacetylcefotaxime for critically ill paediatric patients. Can we use microsampling?. Journal of Antimicrobial Chemotherapy, 77 (8), 2227-2237. doi: 10.1093/jac/dkac168

Vancomycin population pharmacokinetic modeling in children using Bayesian estimation and a Non Parametric Approach

Silveira, Anna Luísa Oliveira, da Silva Alves, Geisa Cristina, Xie, Jiao, Roberts, Jason A. and Sanches, Cristina (2022). Vancomycin population pharmacokinetic modeling in children using Bayesian estimation and a Non Parametric Approach. Brazilian Journal of Pharmaceutical Sciences, 58 e19313, 1-7. doi: 10.1590/s2175-97902020000X2e19313

Epidemiology and microbiology of severe community‐acquired pneumonia in Central Australia: a retrospective study

Tsai, Danny, Chiong, Fabian, Secombe, Paul, Hnin, Khin Moe, Stewart, Penny, Goud, Rajendra, Woodman, Richard, Lipman, Jeffrey, Roberts, Jason and Hewagama, Saliya (2022). Epidemiology and microbiology of severe community‐acquired pneumonia in Central Australia: a retrospective study. Internal Medicine Journal, 52 (6), 1048-1056. doi: 10.1111/imj.15171

Peace, not war in Ukraine or anywhere else, please

Lefrant, Jean-Yves, Pirracchio, Romain, Benhamou, Dan, Fischer, Marc-Olivier, Njeim, Rosanna, Allaouchiche, Bernard, Bastide, Sophie, Biais, Matthieu, Bouvet, Lionel, Brissaud, Olivier, Brull, Sorin J., Capdevila, Xavier, Clausen, Nicola, Cuvillon, Philippe, Dadure, Christophe, David, Jean-Stéphane, Du, Bin, Einav, Sharon, Eley, Victoria, Forget, Patrice, Fujii, Tomoko, Godier, Anne, Gopalan, Dean P., Hamada, Sophie, Hasanin, Ahmed, Joannes-boyau, Olivier, Kerever, Sébastien, Kipnis, Éric, Kolodzie, Kerstin ... Bouaziz, Hervé (2022). Peace, not war in Ukraine or anywhere else, please. Anaesthesia Critical Care and Pain Medicine, 41 (3) 101068, 101068. doi: 10.1016/j.accpm.2022.101068

Population pharmacokinetics of ciprofloxacin in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Levkovich, Bianca J., Pellegrino, Vincent, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Roberts, Jason A., Shekar, Kiran, Fraser, John F. and ASAP ECMO Investigators (2022). Population pharmacokinetics of ciprofloxacin in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Anaesthesia Critical Care and Pain Medicine, 41 (3) 101080, 1-6. doi: 10.1016/j.accpm.2022.101080

Therapeutic drug monitoring and prolonged infusions of Ceftolozane/Tazobactam for MDR/XDR Pseudomonas aeruginosa infections: An observational study

Navarrete-Rouco, María Eugenia, Luque, Sònia, Sorlí, Luisa, Benítez-Cano, Adela, Roberts, Jason A. and Grau, Santiago (2022). Therapeutic drug monitoring and prolonged infusions of Ceftolozane/Tazobactam for MDR/XDR Pseudomonas aeruginosa infections: An observational study. European Journal of Drug Metabolism and Pharmacokinetics, 47 (4), 561-566. doi: 10.1007/s13318-022-00772-x

Population pharmacokinetics and dose optimization of intravenous levofloxacin in hospitalized adult patients

Setiawan, Eko, Abdul-Aziz, Mohd-Hafiz, Cotta, Menino Osbert, Susaniwati, Susaniwati, Cahjono, Heru, Sari, Ika Yunita, Wibowo, Tjipto, Marpaung, Ferdy Royland and Roberts, Jason A. (2022). Population pharmacokinetics and dose optimization of intravenous levofloxacin in hospitalized adult patients. Scientific Reports, 12 (1) 8930, 1-11. doi: 10.1038/s41598-022-12627-1

Evaluation of the stability of temocillin in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy in accordance with the requirements of the UK NHS Yellow Cover Document

Sime, Fekade Bruck, Wallis, Steven, Jamieson, Conor, Hills, Tim, Gilchrist, Mark, Santillo, Mark, Seaton, R Andrew, Drummond, Felicity and Roberts, Jason (2022). Evaluation of the stability of temocillin in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy in accordance with the requirements of the UK NHS Yellow Cover Document. European Journal of Hospital Pharmacy, 30 (e1), ejhpharm-2022. doi: 10.1136/ejhpharm-2022-003286

Multicenter population pharmacokinetic study of unbound ceftriaxone in critically ill patients

Heffernan, Aaron J., Sime, Fekade B., Kumta, Nilesh, Wallis, Steven C., McWhinney, Brett, Ungerer, Jacobus, Wong, Gloria, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2022). Multicenter population pharmacokinetic study of unbound ceftriaxone in critically ill patients. Antimicrobial Agents and Chemotherapy, 66 (6), e0218921. doi: 10.1128/aac.02189-21

Correction to: Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial (Intensive Care Medicine, (2022), 48, 3, (311-321), 10.1007/s00134-021-06609-6)

Hagel, Stefan, Bach, Friedhelm, Brenner, Thorsten, Bracht, Hendrik, Brinkmann, Alexander, Annecke, Thorsten, Hohn, Andreas, Weigand, Markus Alexander, Michels, Guido, Kluge, Stefan, Nierhaus, Axel, Jarczak, Dominik, König, Christina, Weismann, Dirk, Frey, Otto, Witzke, Dominic, Müller, Carsten, Bauer, Michael, Kiehntopf, Michael, Neugebauer, Sophie, Lehmann, Thomas, Roberts, Jason A., Pletz, Mathias W., Braune, Anke, Schmidt, Karsten, Motsch, Johann, Pinder, Nadine, Richter, Daniel, Schlattmann, Peter ... Chkirni, Hicham (2022). Correction to: Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial (Intensive Care Medicine, (2022), 48, 3, (311-321), 10.1007/s00134-021-06609-6). Intensive Care Medicine, 48 (5), 646-647. doi: 10.1007/s00134-022-06668-3

Efficacy and safety of carbapenems versus new antibiotics for treatment of adult patients with complicated urinary tract infections: a systematic review and meta-analysis

Ezure, Yukiko, Rico, Veronica, Paterson, David L., Hall, Lisa, Harris, Patrick N. A., Soriano, Alex, Roberts, Jason A., Bassetti, Matteo, Roberts, Matthew J., Righi, Elda and Wright, Hugh (2022). Efficacy and safety of carbapenems versus new antibiotics for treatment of adult patients with complicated urinary tract infections: a systematic review and meta-analysis. Open Forum Infectious Diseases, 9 (5) ofaa480, ofaa480. doi: 10.1093/ofid/ofaa480

Population pharmacokinetics and toxicodynamics of continuously infused linezolid in critically-ill patients

Wicha, Sebastian G., Mair, Andrea, Chiriac, Ute, Frey, Otto R., Fuchs, Thomas, Gaasch, Max, Hagel, Stefan, Richter, Daniel C., Roberts, Jason A., Röhr, Anka C., Weigand, Markus A. and Brinkmann, Alexander (2022). Population pharmacokinetics and toxicodynamics of continuously infused linezolid in critically-ill patients. International Journal of Antimicrobial Agents, 59 (5) 106572, 106572. doi: 10.1016/j.ijantimicag.2022.106572

Evaluating mono- and combination therapy of meropenem and amikacin against Pseudomonas aeruginosa bacteremia in the hollow-fiber infection model

Avent, Minyon L., McCarthy, Kate L., Sime, Fekade B., Naicker, Saiyuri, Heffernan, Aaron J., Wallis, Steven C., Paterson, David L. and Roberts, Jason A. (2022). Evaluating mono- and combination therapy of meropenem and amikacin against Pseudomonas aeruginosa bacteremia in the hollow-fiber infection model. Microbiology Spectrum, 10 (3), e0052522. doi: 10.1128/spectrum.00525-22

Use of the hollow-fiber infection model to measure the effect of combination therapy of septic shock exposures of Meropenem and Ciprofloxacin against intermediate and resistant Pseudomonas aeruginosa clinical Isolates

Karabasevic, Natalija, Roberts, Jason A., Stronach, Luke, Naicker, Saiyuri, Wallis, Steven C., Sjövall, Fredrik and Sime, Fekade (2022). Use of the hollow-fiber infection model to measure the effect of combination therapy of septic shock exposures of Meropenem and Ciprofloxacin against intermediate and resistant Pseudomonas aeruginosa clinical Isolates. Antimicrobial Agents and Chemotherapy, 66 (5) e0214021, e0214021. doi: 10.1128/aac.02140-21

Treatment of ventilator-associated pneumonia due to carbapenem-resistant Gram-negative bacteria with novel agents: a contemporary, multidisciplinary ESGCIP perspective

Giacobbe, Daniele Roberto, Roberts, Jason A., Abdul-Aziz, Mohd H., de Montmollin, Etienne, Timsit, Jean-François and Bassetti, Matteo (2022). Treatment of ventilator-associated pneumonia due to carbapenem-resistant Gram-negative bacteria with novel agents: a contemporary, multidisciplinary ESGCIP perspective. Expert Review of Anti-infective Therapy, 20 (7), 1-17. doi: 10.1080/14787210.2022.2063838

Oral antivirals for mild–moderate COVID-19: a panacea or a logistical and clinical conundrum?

Coombes, Ian D., Legg, Amy, Patterson, Tina, Kelly, Tanya, Henderson, Andrew and Roberts, Jason A. (2022). Oral antivirals for mild–moderate COVID-19: a panacea or a logistical and clinical conundrum?. Australian Prescriber, 45 (2), 67-68. doi: 10.18773/austprescr.2022.021

Pharmacokinetics and pharmacodynamics of beta-lactam antibiotics in critically ill patients

Sulaiman, Helmi, Roberts, Jason A. and Abdul-Aziz, Mohd H. (2022). Pharmacokinetics and pharmacodynamics of beta-lactam antibiotics in critically ill patients. Farmacia Hospitalaria, 46 (3), 182-190. doi: 10.7399/fh.13170

Pharmacokinetics and pharmacodynamics of beta-lactam antibiotics in critically ill patients

Sulaiman, Helmi, Roberts, Jason A. and Abdul-Aziz, Mohd H. (2022). Pharmacokinetics and pharmacodynamics of beta-lactam antibiotics in critically ill patients. Farmacia Hospitalaria, 46 (3), 182-190. doi: 10.7399/fh.13170

Hospital-based antimicrobial stewardship programs used in low- and middle-income countries: a scoping review

Setiawan, Eko, Abdul-Aziz, Mohd-Hafiz, Roberts, Jason A. and Cotta, Menino Osbert (2022). Hospital-based antimicrobial stewardship programs used in low- and middle-income countries: a scoping review. Microbial Drug Resistance, 28 (5), 566-584. doi: 10.1089/mdr.2021.0363

Population pharmacokinetic model of piperacillin in critically ill patients and describing interethnic variation using external validation

Sanches, Cristina, Alves, Geisa C. S., Farkas, Andras, da Silva, Samuel Dutra, de Castro, Whocely Victor, Chequer, Farah Maria Drummond, Beraldi-Magalhães, Francisco, Magalhães, Igor Rafael dos Santos, Baldoni, André de Oliveira, Chatfield, Mark D., Lipman, Jeffrey, Roberts, Jason A. and Parker, Suzanne L. (2022). Population pharmacokinetic model of piperacillin in critically ill patients and describing interethnic variation using external validation. Antibiotics, 11 (4) 434, 434. doi: 10.3390/antibiotics11040434

Pharmacokinetics of valganciclovir and voriconazole during prolonged intermittent renal replacement therapy in a lung transplant recipient

Whitmore, Timothy J., Cheng, Vesa, Rawlins, Matthew D., Morgan, David, Chang, Tim, O'Halloran, Sean, Dyer, John R., Boan, Peter and Roberts, Jason A. (2022). Pharmacokinetics of valganciclovir and voriconazole during prolonged intermittent renal replacement therapy in a lung transplant recipient. Transplant Infectious Disease, 24 (2) e13818, e13818. doi: 10.1111/tid.13818

Population pharmacokinetics and dosing simulations of ceftriaxone in critically ill patients receiving extracorporeal membrane oxygenation (An ASAP ECMO Study)

Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Gilder, Eileen, Kim, Hyung-Sook, Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Fraser, John F., Shekar, Kiran, Roberts, Jason A. and ASAP ECMO Investigators (2022). Population pharmacokinetics and dosing simulations of ceftriaxone in critically ill patients receiving extracorporeal membrane oxygenation (An ASAP ECMO Study). Clinical Pharmacokinetics, 61 (6), 847-856. doi: 10.1007/s40262-021-01106-x

Influence of PEGylated porous silicon nanoparticles on permeation and efflux of an orally administered antibiotic

Raza, A., Kamato, D., Sime, F.B., Roberts, J.A., Popat, A., Falconer, J.R. and Kumeria, T. (2022). Influence of PEGylated porous silicon nanoparticles on permeation and efflux of an orally administered antibiotic. Materials Today Advances, 13 100210, 100210. doi: 10.1016/j.mtadv.2022.100210

Indonesian healthcare providers' perceptions and attitude on antimicrobial resistance, prescription and stewardship programs

Setiawan, Eko, Cotta, Menino O., Abdul-Aziz, Mohd Hafiz, Sosilya, Hernycane, Widjanarko, Doddy, Wardhani, Dian K. and Roberts, Jason A. (2022). Indonesian healthcare providers' perceptions and attitude on antimicrobial resistance, prescription and stewardship programs. Future Microbiology, 17 (5), 363-375. doi: 10.2217/fmb-2021-0193

Oral fosfomycin activity against Klebsiella pneumoniae in a dynamic bladder infection in vitro model

Abbott, Iain J., van Gorp, Elke, Wyres, Kelly L., Wallis, Steven C., Roberts, Jason A., Meletiadis, Joseph and Peleg, Anton Y. (2022). Oral fosfomycin activity against Klebsiella pneumoniae in a dynamic bladder infection in vitro model. Journal of Antimicrobial Chemotherapy, 77 (5), 1324-1333. doi: 10.1093/jac/dkac045

Cefepime precision dosing tool: from standard to precise dose using nonparametric population pharmacokinetics

Alshaer, Mohammad H., Goutelle, Sylvain, Santevecchi, Barbara, Shoulders, Bethany, Venugopalan, Veena, Cherabuddi, Kartikeya, Liu, Jiajun, Kiel, Patrick J., Roberts, Jason A., Sime, Fekade Bruck, Scheetz, Marc H., Neely, Michael N. and Peloquin, Charles A. (2022). Cefepime precision dosing tool: from standard to precise dose using nonparametric population pharmacokinetics. Antimicrobial Agents and Chemotherapy, 66 (2) e02046-21, 1-9. doi: 10.1128/aac.02046-21

Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial

Hagel, Stefan, Bach, Friedhelm, Brenner, Thorsten, Bracht, Hendrik, Brinkmann, Alexander, Annecke, Thorsten, Hohn, Andreas, Weigand, Markus, Michels, Guido, Kluge, Stefan, Nierhaus, Axel, Jarczak, Dominik, König, Christina, Weismann, Dirk, Frey, Otto, Witzke, Dominic, Müller, Carsten, Bauer, Michael, Kiehntopf, Michael, Neugebauer, Sophie, Lehmann, Thomas, Roberts, Jason A., Pletz, Mathias W., Braune, Anke, Schmidt, Karsten, Motsch, Johann, Pinder, Nadine, Richter, Daniel, Schlattmann, Peter ... Chkirni, Hicham (2022). Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial. Intensive Care Medicine, 48 (3), 311-321. doi: 10.1007/s00134-021-06609-6

Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study

Parker, Suzanne L., Irwin, Adam D., Hosking, Francine, August, Deanne, Schoenmaker, Brittany, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Davies, Mark W. (2022). Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study. International Journal of Antimicrobial Agents, 59 (2) 106513, 1-2. doi: 10.1016/j.ijantimicag.2021.106513

Pandora’s box: Paxlovid, prescribing, pharmacists and pandemic

Roberts, Jason A., Duncan, Alison and Cairns, Kelly A. (2022). Pandora’s box: Paxlovid, prescribing, pharmacists and pandemic. Journal of Pharmacy Practice and Research, 52 (1), 1-4. doi: 10.1002/jppr.1799

Population pharmacokinetics of intraperitoneal gentamicin and the impact of varying dwell times on pharmacodynamic target attainment in patients with acute peritonitis undergoing peritoneal dialysis

Farkas, Andras, Oikonomou, Katerina, Ghanbar, Mohammad, Villasurda, Phillip, Varghese, Julie, Lipman, Jeffrey, Sassine, Joseph, Ranganathan, Dwarakanathan and Roberts, Jason A. (2022). Population pharmacokinetics of intraperitoneal gentamicin and the impact of varying dwell times on pharmacodynamic target attainment in patients with acute peritonitis undergoing peritoneal dialysis. Antimicrobial Agents and Chemotherapy, 66 (2) e01679-21, e0167921. doi: 10.1128/aac.01679-21

Prospective study of policies and use of therapies for COVID-19 among Australian health services during 2020

Smith, Emma L., Gwee, Amanda, Roberts, Jason A., Molton, James S., Wurzel, Danielle, Hughes, Carly M. and Rogers, Benjamin A. (2022). Prospective study of policies and use of therapies for COVID-19 among Australian health services during 2020. Internal Medicine Journal, 52 (2), 214-222. doi: 10.1111/imj.15510

Therapeutic drug monitoring of antibiotic drugs in patients receiving continuous renal replacement therapy or intermittent hemodialysis: A critical review

Matusik, Elodie, Boidin, Clément, Friggeri, Arnaud, Richard, Jean-Christophe, Bitker, Laurent, Roberts, Jason A. and Goutelle, Sylvain (2022). Therapeutic drug monitoring of antibiotic drugs in patients receiving continuous renal replacement therapy or intermittent hemodialysis: A critical review. Therapeutic Drug Monitoring, 44 (1), 86-102. doi: 10.1097/FTD.0000000000000941

In vitro effect of synovial fluid from patients undergoing arthroplasty surgery on MRSA biofilm formation

Pant, Narayan, Wallis, Steven C., Roberts, Jason A. and Eisen, Damon P. (2022). In vitro effect of synovial fluid from patients undergoing arthroplasty surgery on MRSA biofilm formation. Journal of Antimicrobial Chemotherapy, 77 (4), 1041-1044. doi: 10.1093/jac/dkab497

Population pharmacokinetics of vancomycin in critically ill adult patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Jakob, Stephan M., Kim, Hyung-Sook, Levkovich, Bianca J., Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Zacharias, David, Fraser, John F., Shekar, Kiran, Roberts, Jason A. and on behalf of ASAP ECMO Investigators (2022). Population pharmacokinetics of vancomycin in critically ill adult patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Antimicrobial Agents and Chemotherapy, 66 (1) AAC0137721, 1-10. doi: 10.1128/aac.01377-21

Effect of different Piperacillin-Tazobactam dosage regimens on synergy of the combination with Tobramycin against Pseudomonas aeruginosa for the pharmacokinetics of critically ill patients in a dynamic infection model

Tait, Jessica R., Bilal, Hajira, Rogers, Kate E., Lang, Yinzhi, Kim, Tae-Hwan, Zhou, Jieqiang, Wallis, Steven C., Bulitta, Jürgen B., Kirkpatrick, Carl M. J., Paterson, David L., Lipman, Jeffrey, Bergen, Phillip J., Roberts, Jason A., Nation, Roger L. and Landersdorfer, Cornelia B. (2022). Effect of different Piperacillin-Tazobactam dosage regimens on synergy of the combination with Tobramycin against Pseudomonas aeruginosa for the pharmacokinetics of critically ill patients in a dynamic infection model. Antibiotics, 11 (1) 101, 101. doi: 10.3390/antibiotics11010101

Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection

De Oliveira, David M. P., Forde, Brian M., Phan, Minh-Duy, Steiner, Bernhard, Zhang, Bing, Zuegg, Johannes, El-deeb, Ibrahim M., Li, Gen, Keller, Nadia, Brouwer, Stephan, Harbison-Price, Nichaela, Cork, Amanda J., Bauer, Michelle J., Alquethamy, Saleh F., Beatson, Scott A., Roberts, Jason A., Paterson, David L., McEwan, Alastair G., Blaskovich, Mark A. T., Schembri, Mark A., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2022). Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection. mBio, 13 (1) e03517, e0351721. doi: 10.1128/mbio.03517-21

Evaluation of low-volume plasma sampling for the analysis of meropenem in clinical samples

Parker, Suzanne L., Wallis, Steven C., Fourie, Cheryl, Lassig-Smith, Melissa, Starr, Therese, Chikatamarla, Avinash, Dorofaeff, Tavey, Chatfield, Mark D., Lipman, Jeffrey and Roberts, Jason A. (2022). Evaluation of low-volume plasma sampling for the analysis of meropenem in clinical samples. Analytical and Bioanalytical Chemistry, 414 (6), 2155-2162. doi: 10.1007/s00216-021-03851-1

Perioperative cefazolin prophylaxis in pediatric cardiac surgery: a prospective, cohort study

Suna, Jessica, Moloney, Gregory, Marathe, Supreet P., Bierbach, Benjamin, Roberts, Jason A., Parker, Suzanne, Ungerer, Jacobus P.J., McWhinney, Brett, Dorofaeff, Tavey, Venugopal, Prem and Alphonso, Nelson (2022). Perioperative cefazolin prophylaxis in pediatric cardiac surgery: a prospective, cohort study. Annals of Thoracic Surgery, 114 (4), 1434-1440. doi: 10.1016/j.athoracsur.2022.02.047

Pharmacodynamics of ceftriaxone for the treatment of methicillin‐susceptible Staphylococcus aureus: is it a viable treatment option?

Heffernan, A.J., Sime, F.B., Lim, S. Mohd Sazlly, Adiraju, S., Wallis, S.C., Lipman, J., Grant, G.D. and Roberts, J.A. (2022). Pharmacodynamics of ceftriaxone for the treatment of methicillin‐susceptible Staphylococcus aureus: is it a viable treatment option?. International Journal of Antimicrobial Agents, 59 (3) 106537, 106537. doi: 10.1016/j.ijantimicag.2022.106537

Caspofungin population pharmacokinetic analysis in plasma and peritoneal fluid in septic patients with intra-abdominal infections: a prospective cohort study

Garbez, Nicolas, Mbatchi, Litaty C., Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). Caspofungin population pharmacokinetic analysis in plasma and peritoneal fluid in septic patients with intra-abdominal infections: a prospective cohort study. Clinical Pharmacokinetics, 61 (5), 673-686. doi: 10.1007/s40262-021-01062-6

Is dosing of ethambutol as part of a fixed-dose combination product optimal for mechanically ventilated ICU patients with tuberculosis? A population pharmacokinetic study

Beraldi-Magalhaes, Francisco, Parker, Suzanne L., Sanches, Cristina, Sousa Garcia, Leandro, Souza Carvalho, Brenda Karoline, Fachi, Mariana Millan, de Liz, Marcus Vinicius, Pontarolo, Roberto, Lipman, Jeffrey, Cordeiro-Santos, Marcelo and Roberts, Jason A. (2021). Is dosing of ethambutol as part of a fixed-dose combination product optimal for mechanically ventilated ICU patients with tuberculosis? A population pharmacokinetic study. Antibiotics, 10 (12) 1559. doi: 10.3390/antibiotics10121559

A personalised approach to antibiotic pharmacokinetics and pharmacodynamics in critically ill patients

Heffernan, Aaron J., Mohd Sazlly Lim, Sazlyna, Lipman, Jeffrey and Roberts, Jason A. (2021). A personalised approach to antibiotic pharmacokinetics and pharmacodynamics in critically ill patients. Anaesthesia Critical Care and Pain Medicine, 40 (6) 100970, 100970. doi: 10.1016/j.accpm.2021.100970

An international survey on aminoglycoside practices in critically ill patients: the AMINO III study

Roger, Claire, Louart, Benjamin, Elotmani, Loubna, Barton, Greg, Escobar, Leslie, Koulenti, Despoina, Lipman, Jeffrey, Leone, Marc, Muller, Laurent, Boutin, Caroline, Amour, Julien, Banakh, Iouri, Cousson, Joel, Bourenne, Jeremy, Constantin, Jean-Michel, Albanese, Jacques, Roberts, Jason A., Lefrant, Jean-Yves, Darchy, Bruno, Sigismond, Lasocki, Debbat, Karim, Moschietto, Sébastien, Capellier, Gilles, Biais, Matthieu, Brunin, Guillaume, Huet, Olivier, Hausermann, Marie-Hélène, Just, Bernard, Constantin, Jean-Michel ... Felton, Timothy (2021). An international survey on aminoglycoside practices in critically ill patients: the AMINO III study. Annals of Intensive Care, 11 (1) 49, 49. doi: 10.1186/s13613-021-00834-4

Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials

Axfors, Cathrine, Janiaud, Perrine, Schmitt, Andreas M., van’t Hooft, Janneke, Smith, Emily R., Haber, Noah A., Abayomi, Akin, Abduljalil, Manal, Abdulrahman, Abdulkarim, Acosta-Ampudia, Yeny, Aguilar-Guisado, Manuela, Al-Beidh, Farah, Alejandria, Marissa M., Alfonso, Rachelle N., Ali, Mohammad, AlQahtani, Manaf, AlZamrooni, Alaa, Anaya, Juan-Manuel, Ang, Mark Angelo C., Aomar, Ismael F., Argumanis, Luis E., Averyanov, Alexander, Baklaushev, Vladimir P., Balionis, Olga, Benfield, Thomas, Berry, Scott, Birocco, Nadia, Bonifacio, Lynn B., Bowen, Asha C. ... Hemkens, Lars G. (2021). Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials. BMC Infectious Diseases, 21 (1) 1170, 1170. doi: 10.1186/s12879-021-06829-7

A loading micafungin dose in critically ill patients undergoing continuous veno-venous hemofiltration or continuous veno-venous hemodiafiltration: a population pharmacokinetic analysis

Garbez, Nicolas, Mbatchi, Litaty C., Maseda, Emilio, Luque, Sonia, Grau, Santiago, Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). A loading micafungin dose in critically ill patients undergoing continuous veno-venous hemofiltration or continuous veno-venous hemodiafiltration: a population pharmacokinetic analysis. Therapeutic Drug Monitoring, 43 (6), 747-755. doi: 10.1097/FTD.0000000000000874

Dose optimisation of antibiotics used for meningitis

Heffernan, Aaron J. and Roberts, Jason A. (2021). Dose optimisation of antibiotics used for meningitis. Current Opinion in Infectious Diseases, 34 (6), 581-590. doi: 10.1097/QCO.0000000000000783

Exploring the pharmacokinetics of phenoxymethylpenicillin (Penicillin-V) in adults: a healthy volunteer study

Rawson, Timothy M., Wilson, Richard C., Moore, Luke S. P., Macgowan, Alasdair P., Lovering, Andrew M., Bayliss, Mark, Kyriakides, Mathew, Gilchrist, Mark, Roberts, Jason A., Hope, William W. and Holmes, Alison H. (2021). Exploring the pharmacokinetics of phenoxymethylpenicillin (Penicillin-V) in adults: a healthy volunteer study. Open Forum Infectious Diseases, 8 (12) ofab573, ofab573. doi: 10.1093/ofid/ofab573

Population pharmacokinetics of cefepime in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Jakob, Stephan M., Levkovich, Bianca J., Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Zacharias, David, Roberts, Jason A., Shekar, Kiran, Fraser, John F. and on behalf ofASAP ECMO Investigators (2021). Population pharmacokinetics of cefepime in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). International Journal of Antimicrobial Agents, 58 (6) 106466, 1-8. doi: 10.1016/j.ijantimicag.2021.106466

Micafungin population PK analysis in healthy and septic pigs: can the septic porcine model predict the micafungin PK in septic patients?

Garbez, Nicolas, Mbatchi, Litaty C., Louart, Guillaume, Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). Micafungin population PK analysis in healthy and septic pigs: can the septic porcine model predict the micafungin PK in septic patients?. Pharmaceutical Research, 38 (11), 1863-1871. doi: 10.1007/s11095-021-03137-2

Therapeutic drug monitoring of antibiotics: defining the therapeutic range

Abdul–Aziz, Mohd H., Brady, Kara, Cotta, Menino Osbert and Roberts, Jason A. (2021). Therapeutic drug monitoring of antibiotics: defining the therapeutic range. Therapeutic Drug Monitoring, 44 (1), 19-31. doi: 10.1097/ftd.0000000000000940

Consensus guidelines for antifungal prophylaxis in haematological malignancy and haemopoietic stem cell transplantation, 2021

Teh, Benjamin W., Yeoh, Daniel K., Haeusler, Gabrielle M., Yannakou, Costas K., Fleming, Shaun, Lindsay, Julian, Slavin, Monica A., Chang, Christina C, Blyth, Christopher C, Chen, Sharon C-A, Khanina, Anna, Morrissey, C. Orla, Roberts, Jason A., Thursky, Karin A and Worth, Leon (2021). Consensus guidelines for antifungal prophylaxis in haematological malignancy and haemopoietic stem cell transplantation, 2021. Internal Medicine Journal, 51 (S7), 67-88. doi: 10.1111/imj.15588

Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy and haemopoietic stem cell transplant recipients, 2021

Chau, Maggie M., Daveson, Kathryn, Alffenaar, Jan-Willem C., Gwee, Amanda, Ho, Su Ann, Marriott, Deborah J. E., Trubiano, Jason A., Zhao, Jessie, Roberts, Jason A., Chang, Christina C, Blyth, Christopher C, Chen, Sharon C-A, Khanina, Anna, Morrissey, C. Orla, Thursky, Karin A, Worth, Leon and Slavin, Monica A (2021). Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy and haemopoietic stem cell transplant recipients, 2021. Internal Medicine Journal, 51 (S7), 37-66. doi: 10.1111/imj.15587

Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021

Evans, Laura, Rhodes, Andrew, Alhazzani, Waleed, Antonelli, Massimo, Coopersmith, Craig M., French, Craig, Machado, Flávia R, Mcintyre, Lauralyn, Ostermann, Marlies, Prescott, Hallie C., Schorr, Christa, Simpson, Steven, Joost Wiersinga, W., Alshamsi, Fayez, Angus, Derek C., Arabi, Yaseen, Azevedo, Luciano, Beale, Richard, Beilman, Gregory, Belley-Cote, Emilie, Burry, Lisa, Cecconi, Maurizio, Centofanti, John, Yataco, Angel Coz, De Waele, Jan, Dellinger, R Phillip, Doi, Kent, Du, Bin, Estenssoro, Elisa ... Levy, Mitchell (2021). Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021. Critical Care Medicine, 49 (11), 1974-1982. doi: 10.1097/CCM.0000000000005357

Introduction to the updated Australasian consensus guidelines for the management of invasive fungal disease and use of antifungal agents in the haematology/oncology setting, 2021

Chang, Christina C., Blyth, Christopher C., Chen, Sharon C-A, Khanina, Anna, Morrissey, C Orla, Roberts, Jason A., Thursky, Karin A., Worth, Leon J. and Slavin, Monica A. (2021). Introduction to the updated Australasian consensus guidelines for the management of invasive fungal disease and use of antifungal agents in the haematology/oncology setting, 2021. Internal medicine journal, 51 (S7), 3-17. doi: 10.1111/imj.15585

Population pharmacokinetics of piperacillin and tazobactam in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Jakob, Stephan M, Kim, Hyung-Sook, Levkovich, Bianca J., Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Zacharias, David, Fraser, John F., Shekar, Kiran, Roberts, Jason A. and on behalf of ASAP ECMO Investigators (2021). Population pharmacokinetics of piperacillin and tazobactam in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Antimicrobial Agents and Chemotherapy, 65 (11) e01438-21, 1-11. doi: 10.1128/aac.01438-21

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021

Evans, Laura, Rhodes, Andrew, Alhazzani, Waleed, Antonelli, Massimo, Coopersmith, Craig M., French, Craig, Machado, Flávia R, Mcintyre, Lauralyn, Ostermann, Marlies, Prescott, Hallie C., Schorr, Christa, Simpson, Steven, Wiersinga, W Joost, Alshamsi, Fayez, Angus, Derek C., Arabi, Yaseen, Azevedo, Luciano, Beale, Richard, Beilman, Gregory, Belley-Cote, Emilie, Burry, Lisa, Cecconi, Maurizio, Centofanti, John, Coz Yataco, Angel, De Waele, Jan, Dellinger, R Phillip, Doi, Kent, Du, Bin, Estenssoro, Elisa ... Levy, Mitchell (2021). Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Critical Care Medicine, 49 (11), e1063-e1143. doi: 10.1097/CCM.0000000000005337

2021 adaptation of the editorial policy of Anaesthesia Critical Care and Pain Medicine (ACCPM)

Lefrant, Jean-Yves, Pirracchio, Romain, Benhamou, Dan, Njeim, Rosanna, Ausset, Sylvain, Bastide, Sophie, Biais, Matthieu, Bouvet, Lionel, Brissaud, Olivier, Brull, Sorin J., Capdevila, Xavier, Cuvillon, Philippe, Dadure, Christophe, David, Jean-Stéphane, Bin, Du, Fischer, Marc-Olivier, Forget, Patrice, Fujii, Tomoko, Godier, Anne, Gopalan, Dean P., Hamada, Sophie, Joannes-Boyau, Olivier, Kerever, Sébastien, Kipnis, Éric, Kolodzie, Kerstin, Landau, Ruth, Le Gall, Arthur, Le Guen, Morgan, Legrand, Matthieu ... Bouaziz, Hervé (2021). 2021 adaptation of the editorial policy of Anaesthesia Critical Care and Pain Medicine (ACCPM). Anaesthesia, Critical Care and Pain Medicine, 40 (5) 100957, 1-5. doi: 10.1016/j.accpm.2021.100957

Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis

Billot, Laurent, Lipman, Jeffrey, Brett, Stephen J., Waele, Jan J. De, Cotta, Menino Osbert, Davis, Joshua S., Finfer, Simon, Hammond, Naomi E., Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roger, Claire, Roberts, Jason A., Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Dulhunty, Joel M. and For the BLING III Investigators (2021). Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis. Critical Care and Resuscitation, 23 (3), 273-284. doi: 10.51893/2021.3.oa4

Applying antimicrobial pharmacokinetic principles for complex patients: critically ill adult patients receiving extracorporeal membrane oxygenation and renal replacement therapy

Cheng, Vesa, Abdul-Aziz, Mohd H. and Roberts, Jason A. (2021). Applying antimicrobial pharmacokinetic principles for complex patients: critically ill adult patients receiving extracorporeal membrane oxygenation and renal replacement therapy. Current Infectious Disease Reports, 23 (9) 13. doi: 10.1007/s11908-021-00757-y

Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO- A case report

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2021). Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO- A case report. International Journal of Antimicrobial Agents, 58 (5) 106431, 106431. doi: 10.1016/j.ijantimicag.2021.106431

Population pharmacokinetics of vancomycin and meropenem in pediatric extracorporeal membrane oxygenation support

Zylbersztajn, Brenda, Parker, Suzanne, Navea, Daniel, Izquierdo, Giannina, Ortiz, Paula, Torres, Juan Pablo, Fajardo, Cristian, Diaz, Rodrigo, Valverde, Cristian and Roberts, Jason (2021). Population pharmacokinetics of vancomycin and meropenem in pediatric extracorporeal membrane oxygenation support. Frontiers in Pharmacology, 12 709332, 1-10. doi: 10.3389/fphar.2021.709332

Emerging therapeutic drug monitoring of anti‐infective agents in Australian hospitals: availability, performance and barriers to implementation

Sandaradura, Indy, Alffenaar, Jan‐Willem, Cotta, Menino O., Daveson, Kathryn, Day, Richard O., Van Hal, Sebastiaan, Lau, Cindy, Marriott, Deborah J. E., Penm, Jonathan, Roberts, Jason A., Tabah, Alexis, Williams, Paul and Imani, Sahand (2021). Emerging therapeutic drug monitoring of anti‐infective agents in Australian hospitals: availability, performance and barriers to implementation. British Journal of Clinical Pharmacology, 88 (2) bcp.14995, 669-679. doi: 10.1111/bcp.14995

Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations

Tu, Quyen, Cotta, Menino, Raman, Sainath, Graham, Nicolette, Schlapbach, Luregn and Roberts, Jason A (2021). Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations. Expert Review of Clinical Pharmacology, 14 (11), 1-17. doi: 10.1080/17512433.2021.1961578

Infrared based saliva screening test for COVID-19

Wood, Bayden R., Kochan, Kamila, Bedolla, Diana E., Salazar-Quiroz, Natalia, Grimley, Samantha L., Perez-Guaita, David, Baker, Matthew J., Vongsvivut, Jitraporn, Tobin, Mark J., Bambery, Keith R., Christensen, Dale, Pasricha, Shivani, Eden, Anthony K., Mclean, Aaron, Roy, Supti, Roberts, Jason A., Druce, Julian, Williamson, Deborah A., McAuley, Julie, Catton, Mike, Purcell, Damian F. J., Godfrey, Dale I. and Heraud, Philip (2021). Infrared based saliva screening test for COVID-19. Angewandte Chemie - International Edition, 60 (31), 17102-17107. doi: 10.1002/anie.202104453

Standard of practice in infectious diseases for pharmacy services

Cairns, Kelly A., Avent, Minyon, Buono, Evette, Cheah, Ron, Devchand, Misha, Khumra, Sharmila, Rawlins, Matthew, Roberts, Jason A., Xenos, Kristin and Munro, Courtney (2021). Standard of practice in infectious diseases for pharmacy services. Journal of Pharmacy Practice and Research, 51 (3), 247-264. doi: 10.1002/jppr.1744

Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)

Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680

Micafungin population PK analysis in plasma and peritoneal fluid in septic patients with intra-abdominal infections: a prospective cohort study

Garbez, Nicolas, Mbatchi, Litaty, Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). Micafungin population PK analysis in plasma and peritoneal fluid in septic patients with intra-abdominal infections: a prospective cohort study. Antimicrobial Agents and Chemotherapy, 65 (7) e02307-20, 1-13. doi: 10.1128/aac.02307-20

Personalized ß-lactam dosing in patients with coronavirus disease 2019 (COVID-19) and pneumonia: A retrospective analysis on pharmacokinetics and pharmacokinetic target attainment

Chiriac, Ute, Frey, Otto R., Roehr, Anka C., Koeberer, Andreas, Gronau, Patrick, Fuchs, Thomas, Roberts, Jason A. and Brinkmann, Alexander (2021). Personalized ß-lactam dosing in patients with coronavirus disease 2019 (COVID-19) and pneumonia: A retrospective analysis on pharmacokinetics and pharmacokinetic target attainment. Medicine, 100 (22) e26253, 1-7. doi: 10.1097/MD.0000000000026253

Personalized piperacillin dosing for the critically ill: a retrospective analysis of clinical experience with dosing software and therapeutic drug monitoring to optimize antimicrobial dosing

Chiriac, Ute, Richter, Daniel C., Frey, Otto R., Röhr, Anka C., Helbig, Sophia, Preisenberger, Judit, Hagel, Stefan, Roberts, Jason A., Weigand, Markus A. and Brinkmann, Alexander (2021). Personalized piperacillin dosing for the critically ill: a retrospective analysis of clinical experience with dosing software and therapeutic drug monitoring to optimize antimicrobial dosing. Antibiotics, 10 (6) 667, 667. doi: 10.3390/antibiotics10060667

A systematic review of the clinical pharmacokinetics, pharmacodynamics and toxicodynamics of ganciclovir/valganciclovir in allogeneic haematopoietic stem cell transplant patients

Selby, Philip Roland, Shakib, Sepehr, Peake, Sandra L., Warner, Morgyn S., Yeung, David, Hahn, Uwe and Roberts, Jason A. (2021). A systematic review of the clinical pharmacokinetics, pharmacodynamics and toxicodynamics of ganciclovir/valganciclovir in allogeneic haematopoietic stem cell transplant patients. Clinical Pharmacokinetics, 60 (6), 727-739. doi: 10.1007/s40262-020-00982-z

Nebulized colistin in ventilator-associated pneumonia and tracheobronchitis: historical background, pharmacokinetics and perspectives

Zhu, Yinggang, Monsel, Antoine, Roberts, Jason A., Pontikis, Konstantinos, Mimoz, Olivier, Rello, Jordi, Qu, Jieming, Rouby, Jean-Jacques, on behalf of the European Investigator Network for Nebulized Antibiotics in Ventilator-Associated Pneumonia (ENAVAP) and Li Bassi, Gianluigi (2021). Nebulized colistin in ventilator-associated pneumonia and tracheobronchitis: historical background, pharmacokinetics and perspectives. Microorganisms, 9 (6) 1154, 1-25. doi: 10.3390/microorganisms9061154

Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children

Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Roberts, Jason A., Lipman, Jeffrey, Coulthard, Mark G., Sparkes, Louise, Wallis, Steven C. and Parker, Suzanne L. (2021). Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children. Analytical and Bioanalytical Chemistry, 413 (17), 4483-4491. doi: 10.1007/s00216-021-03411-7

Microsampling to support pharmacokinetic clinical studies in pediatrics

Guerra Valero, Yarmarly, Dorofaeff, Tavey, Parker, Lisa, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2021). Microsampling to support pharmacokinetic clinical studies in pediatrics. Pediatric Research, 91 (6), 1-5. doi: 10.1038/s41390-021-01586-4

Pharmacodynamic evaluation of a single dose versus a 24-hour course of multiple doses of cefazolin for surgical prophylaxis

Heffernan, Aaron, Alawie, Jowana, Wallis, Steven C., Naicker, Saiyuri, Adiraju, Santosh, Roberts, Jason A. and Sime, Fekade Bruck (2021). Pharmacodynamic evaluation of a single dose versus a 24-hour course of multiple doses of cefazolin for surgical prophylaxis. Antibiotics, 10 (5) 602, 602. doi: 10.3390/antibiotics10050602

Clinical pharmacokinetic and pharmacodynamic considerations in the drug treatment of non-tuberculous mycobacteria in cystic fibrosis

Burke, Andrew, Smith, Daniel, Coulter, Chris, Bell, Scott C., Thomson, Rachel and Roberts, Jason A. (2021). Clinical pharmacokinetic and pharmacodynamic considerations in the drug treatment of non-tuberculous mycobacteria in cystic fibrosis. Clinical Pharmacokinetics, 60 (9), 1081-1102. doi: 10.1007/s40262-021-01010-4

Epidemiology of extended-spectrum β-lactamase and metallo-β-lactamase-producing in South Asia

Islam, Kamrul, Heffernan, Aaron J., Naicker, Saiyuri, Henderson, Andrew, Chowdhury, Mohammed Abdul Hassan, Roberts, Jason A. and Sime, Fekade B. (2021). Epidemiology of extended-spectrum β-lactamase and metallo-β-lactamase-producing in South Asia. Future Microbiology, 16 (7) fmb-2020-0193, 521-535. doi: 10.2217/fmb-2020-0193

Antibiotic Pharmacokinetics/Pharmacodynamics: Where are we heading?

Li, Jian and Roberts, Jason (2021). Antibiotic Pharmacokinetics/Pharmacodynamics: Where are we heading?. International Journal of Antimicrobial Agents, 58 (2) 106369, 106369. doi: 10.1016/j.ijantimicag.2021.106369

Ceftriaxone exposure in patients undergoing extracorporeal membrane oxygenation

Gijsen, Matthias, Annaert, Pieter, Shekar, Kiran, Roberts, Jason A., Wauters, Joost and Spriet, Isabel (2021). Ceftriaxone exposure in patients undergoing extracorporeal membrane oxygenation. International Journal of Antimicrobial Agents, 57 (5) 106326, 106326. doi: 10.1016/j.ijantimicag.2021.106326

Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery

Raza, Aun, Alavi, Seyed Ebrahim, Sime, Fekade Bruck, Han, Felicity Y., Roberts, Jason A., Popat, Amirali, Falconer, James R. and Kumeria, Tushar (2021). Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery. Acta Biomaterialia, 126, 277-290. doi: 10.1016/j.actbio.2021.03.042

Semi-mechanistic PK/PD modelling of meropenem and sulbactam combination against carbapenem-resistant strains of Acinetobacter baumannii

Mohd Sazlly Lim, Sazlyna, Heffernan, Aaron J., Zowawi, Hosam M., Roberts, Jason A. and Sime, Fekade B. (2021). Semi-mechanistic PK/PD modelling of meropenem and sulbactam combination against carbapenem-resistant strains of Acinetobacter baumannii. European Journal of Clinical Microbiology and Infectious Diseases, 40 (9), 1943-1952. doi: 10.1007/s10096-021-04252-z

Semi-mechanistic PK/PD modelling of fosfomycin and sulbactam combination against carbapenem-resistant Acinetobacter baumannii

Mohd Sazlly Lim, S., Heffernan, A.J., Roberts, J.A. and Sime, F.B. (2021). Semi-mechanistic PK/PD modelling of fosfomycin and sulbactam combination against carbapenem-resistant Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy, 65 (5) e02472-20. doi: 10.1128/aac.02472-20

Impact of the epithelial lining fluid milieu on amikacin pharmacodynamics against Pseudomonas aeruginosa

Heffernan, Aaron J., Sime, Fekade B., Lim, Sazlyna Mohd Sazlly, Naicker, Saiyuri, Andrews, Katherine T., Ellwood, David, Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2021). Impact of the epithelial lining fluid milieu on amikacin pharmacodynamics against Pseudomonas aeruginosa. Drugs in R&D, 21 (2), 203-215. doi: 10.1007/s40268-021-00344-5

Antimicrobial dosing in prolonged intermittent renal replacement therapy: a systematic review

Rawlins, Matthew D. M., Misko, Jeanie and Roberts, Jason A. (2021). Antimicrobial dosing in prolonged intermittent renal replacement therapy: a systematic review. Journal of Pharmacy Practice and Research, 51 (2), 106-120. doi: 10.1002/jppr.1723

Evaluation of meropenem-ciprofloxacin combination dosage regimens for the pharmacokinetics of critically ill patients with augmented renal clearance

Agyeman, Akosua A., Rogers, Kate E., Tait, Jessica R., Bergen, Phillip J., Kirkpatrick, Carl M., Wallis, Steven C., Bulitta, Jürgen B., Paterson, David L., Lipman, Jeffrey, Nation, Roger L., Roberts, Jason A. and Landersdorfer, Cornelia B. (2021). Evaluation of meropenem-ciprofloxacin combination dosage regimens for the pharmacokinetics of critically ill patients with augmented renal clearance. Clinical Pharmacology and Therapeutics, 109 (4), 1104-1115. doi: 10.1002/cpt.2191

Model-informed drug development for anti-infectives: state of the art and future

Rayner, Craig R., Smith, Patrick F., Andes, David, Andrews, Kayla, Derendorf, Hartmut, Friberg, Lena E., Hanna, Debra, Lepak, Alex, Mills, Edward, Polasek, Thomas M., Roberts, Jason A., Schuck, Virna, Shelton, Mark J., Wesche, David and Rowland-Yeo, Karen (2021). Model-informed drug development for anti-infectives: state of the art and future. Clinical Pharmacology and Therapeutics, 109 (4), 867-891. doi: 10.1002/cpt.2198

Standard of ​practice in intensive care for pharmacy services

Johnston, Karlee, Ankravs, Melissa J., Badman, Belinda, Choo, Chui Lynn, Cree, Michele, Fyfe, Rachel, Roberts, Jason A., Xu, Jessica and Munro, Courtney (2021). Standard of ​practice in intensive care for pharmacy services. Journal of Pharmacy Practice and Research, 51 (2), 165-183. doi: 10.1002/jppr.1718

Provider perspectives on beta-lactam therapeutic drug monitoring programs in the critically ill: a protocol for a multicenter mixed-methods study

Barreto, Erin F., Rule, Andrew D., Alshaer, Mohammad H., Roberts, Jason A., Abdul Aziz, Mohd Hafiz, Scheetz, Marc H., Mara, Kristin C., Jannetto, Paul J., Gajic, Ognjen, O'Horo, John C and Boehmer, Kasey R (2021). Provider perspectives on beta-lactam therapeutic drug monitoring programs in the critically ill: a protocol for a multicenter mixed-methods study. Implementation science communications, 2 (1) 34, 34. doi: 10.1186/s43058-021-00134-9

PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery

Raza, Aun, Miles, Jared A., Bruck Sime, Fekade, Ross, Benjamin P., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2021). PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery. International Journal of Pharmaceutics, 597 120280, 120280. doi: 10.1016/j.ijpharm.2021.120280

Protocol for an international, multicentre, prospective, observational study of nosocomial pneumonia in intensive care units: The PneumoINSPIRE study

Koulenti, Despoina, Armaganidis, Apostolos, Arvaniti, Kostoula, Blot, Stijn, Brun-Buisson, Christian, Deja, Maria, De Waele, Jan, Du, Bin, Dulhunty, Joel M., Garcia-Diaz, Julia, Judd, Matthew, Paterson, David L., Putensen, Christian, Reina, Rosa, Rello, Jordi, Restrepo, Marcos I., Roberts, Jason A., Sjovall, Fredrik, Timsit, Jean-Francois, Tsiodras, Sotirios, Zahar, Jean-Ralph, Zhang, Yuchi, Lipman, Jeffrey and On behalf of the Working Group on Pneumonia of the European Society of Intensive Care Medicine (2021). Protocol for an international, multicentre, prospective, observational study of nosocomial pneumonia in intensive care units: The PneumoINSPIRE study. Critical Care and Resuscitation, 23 (1), 59-66. doi: 10.51893/2021.1.oa5

Pharmacodynamics of once- versus twice-daily dosing of nebulized amikacin in an in vitro Hollow-Fiber Infection Model against 3 clinical isolates of Pseudomonas aeruginosa

Heffernan, Aaron James, Sime, Fekade Bruck, Naicker, Saiyuri, Andrews, Katherine, Ellwood, David, Guerra-Valero, Yarmarly, Wallis, Steven, Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason Alexander (2021). Pharmacodynamics of once- versus twice-daily dosing of nebulized amikacin in an in vitro Hollow-Fiber Infection Model against 3 clinical isolates of Pseudomonas aeruginosa. Diagnostic microbiology and infectious disease, 100 (2) 115329, 115329. doi: 10.1016/j.diagmicrobio.2021.115329

Comparative lung distribution of radiolabeled tobramycin between nebulized and intravenous administration in a mechanically-ventilated ovine model, an observational study

Dhanani, Jayesh A., Goodman, Steven, Ahern, Benjamin, Cohen, Jeremy, Fraser, John F., Barnett, Adrian, Diab, Sara, Bhatt, Manoj and Roberts, Jason A. (2021). Comparative lung distribution of radiolabeled tobramycin between nebulized and intravenous administration in a mechanically-ventilated ovine model, an observational study. International Journal of Antimicrobial Agents, 57 (2) 106232, 106232. doi: 10.1016/j.ijantimicag.2020.106232

Population pharmacokinetics analysis of amikacin initial dosing regimen in elderly patients

Kato, Hideo, Parker, Suzanne L., Roberts, Jason A., Hagihara, Mao, Asai, Nobuhiro, Yamagishi, Yuka, Paterson, David L. and Mikamo, Hiroshige (2021). Population pharmacokinetics analysis of amikacin initial dosing regimen in elderly patients. Antibiotics, 10 (2) 100, 1-13. doi: 10.3390/antibiotics10020100

Population pharmacokinetics of levetiracetam in patients with traumatic brain injury and subarachnoid hemorrhage exhibiting augmented renal clearance

Sime, Fekade Bruck, Roberts, Jason A., Jeffree, Rosalind L., Pandey, Saurabh, Adiraju, Santosh, Livermore, Amelia, Butler, Jenie, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Cotta, Menino Osbert (2021). Population pharmacokinetics of levetiracetam in patients with traumatic brain injury and subarachnoid hemorrhage exhibiting augmented renal clearance. Clinical Pharmacokinetics, 60 (5), 655-664. doi: 10.1007/s40262-020-00979-8

Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem

Raza, Aun, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Falconer, James R., Kumeria, Tushar and Popat, Amirali (2021). Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem. ACS Biomaterials Science and Engineering, 7 (5) acsbiomaterials.0c01284, 1836-1853. doi: 10.1021/acsbiomaterials.0c01284

A meta-analysis of protein binding of flucloxacillin in healthy volunteers and hospitalized patients

Wallenburg, Eveline, Brüggemann, Roger J. M., Roberts, Jason A., Jager, Nynke G. L., Ulldemolins, Marta, Wilkes, Sarah, Schouten, Jeroen, Chin, Paul K. L. and ter Heine, Rob (2021). A meta-analysis of protein binding of flucloxacillin in healthy volunteers and hospitalized patients. Clinical Microbiology and Infection, 28 (3), 446.e1-446.e7. doi: 10.1016/j.cmi.2021.06.039

Antimicrobial pharmacokinetics and preclinical in vitro models to support optimized treatment approaches for uncomplicated lower urinary tract infections

Abbott, Iain J., Roberts, Jason A., Meletiadis, Joseph and Peleg, Anton Y. (2021). Antimicrobial pharmacokinetics and preclinical in vitro models to support optimized treatment approaches for uncomplicated lower urinary tract infections. Expert Review of Anti-infective Therapy, 19 (3), 271-295. doi: 10.1080/14787210.2020.1813567

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

Evans, Laura, Rhodes, Andrew, Alhazzani, Waleed, Antonelli, Massimo, Coopersmith, Craig M., French, Craig, Machado, Flávia R., Mcintyre, Lauralyn, Ostermann, Marlies, Prescott, Hallie C., Schorr, Christa, Simpson, Steven, Wiersinga, W. Joost, Alshamsi, Fayez, Angus, Derek C., Arabi, Yaseen, Azevedo, Luciano, Beale, Richard, Beilman, Gregory, Belley-Cote, Emilie, Burry, Lisa, Cecconi, Maurizio, Centofanti, John, Coz Yataco, Angel, De Waele, Jan, Dellinger, R. Phillip, Doi, Kent, Du, Bin, Estenssoro, Elisa ... Levy, Mitchell (2021). Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Medicine, 47 (11), 1181-1247. doi: 10.1007/s00134-021-06506-y

The impact of pharmacist-led antifungal stewardship interventions in the hospital setting: a systematic review

Khanina, Anna, Cairns, Kelly A., Kong, David C. M., Thursky, Karin A., Slavin, Monica A. and Roberts, Jason A. (2021). The impact of pharmacist-led antifungal stewardship interventions in the hospital setting: a systematic review. Journal of Pharmacy Practice and Research, 51 (2), 90-105. doi: 10.1002/jppr.1721

Optimization of Ganciclovir use in allogeneic hematopoietic cell transplant recipients – the role of therapeutic drug monitoring

Ho, Su Ann, Slavin, Monica, Roberts, Jason A. and Yong, Michelle (2020). Optimization of Ganciclovir use in allogeneic hematopoietic cell transplant recipients – the role of therapeutic drug monitoring. Expert Review of Anti-infective Therapy, 19 (6), 1-12. doi: 10.1080/14787210.2021.1851193

A systematic review of studies reporting antibiotic pharmacokinetic data in the cerebrospinal fluid of critically Ill patients with uninflamed meninges

Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey, Wong, Wai Tat, Joynt, Gavin M. and Cotta, Menino Osbert (2020). A systematic review of studies reporting antibiotic pharmacokinetic data in the cerebrospinal fluid of critically Ill patients with uninflamed meninges. Antimicrobial Agents and Chemotherapy, 65 (1) e01998-20, 1-19. doi: 10.1128/aac.01998-20

Cerebrospinal fluid penetration of ceftolozane/tazobactam in critically ill patients with an indwelling external ventricular drain

Sime, Fekade B, Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Cerebrospinal fluid penetration of ceftolozane/tazobactam in critically ill patients with an indwelling external ventricular drain. Antimicrobial Agents and Chemotherapy, 65 (1) e01698-20, 1-11. doi: 10.1128/aac.01698-20

A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Stuart, Janine, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2020). A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies. Clinical Chemistry and Laboratory Medicine (CCLM), 59 (5), 921-933. doi: 10.1515/cclm-2020-1196

Australian National Enterovirus Reference Laboratory annual report, 2019

Hobday, Linda K., Ibrahim, Aishah, Kaye, Matthew E., Bruggink, Leesa, Chanthalavanh, Presa, Garcia-Clapes, Arnau, Roberts, Jason A. and Thorley, Bruce R. (2020). Australian National Enterovirus Reference Laboratory annual report, 2019. Communicable diseases intelligence (2018), 44. doi: 10.33321/cdi.2020.44.94

Oral meropenem for superbugs: challenges and opportunities

Raza, Aun, Ngieng, Shih Chen, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2020). Oral meropenem for superbugs: challenges and opportunities. Drug Discovery Today, 26 (2), 551-560. doi: 10.1016/j.drudis.2020.11.004

Vancomycin serum concentration after 48 h of administration: A 3-years survey in an intensive care unit

Perin, Nicolas, Roger, Claire, Marin, Grégory, Molinari, Nicolas, Evrard, Alexandre, Lavigne, Jean-Philippe, Barbar, Saber, Claret, Pierre Géraud, Boutin, Caroline, Muller, Laurent, Lipman, Jeffrey, Lefrant, Jean-Yves, Jaber, Samir and Roberts, Jason A. (2020). Vancomycin serum concentration after 48 h of administration: A 3-years survey in an intensive care unit. Antibiotics, 9 (11) 793, 1-16. doi: 10.3390/antibiotics9110793

β-lactam dosing strategies: think before you push

Liu, Jiajun, Rhodes, Nathaniel J., Roberts, Jason A., Pais, Gwendolyn M., Turner, Ben, Kiel, Patrick J. and Scheetz, Marc H. (2020). β-lactam dosing strategies: think before you push. International Journal of Antimicrobial Agents, 56 (5) 106151, 106151. doi: 10.1016/j.ijantimicag.2020.106151

Prolonged infusion of beta-lactam antibiotics for Gram-negative infections: rationale and evidence base

Abdul-Aziz, Mohd H., Portunato, Federica and Roberts, Jason A. (2020). Prolonged infusion of beta-lactam antibiotics for Gram-negative infections: rationale and evidence base. Current Opinion in Infectious Diseases, Publish Ahead of Print (6), 501-510. doi: 10.1097/qco.0000000000000681

Therapeutic drug monitoring of commonly used anti-infective agents: A nationwide cross-sectional survey of Australian hospital practices

Imani, Sahand, Alffenaar, Jan-Willem, Cotta, Menino O., Daveson, Kathryn, van Hal, Sebastiaan, Lau, Cindy, Marriott, Debbie, Penm, Jonathan, Roberts, Jason A., Tabah, Alexis, Trethewy, Nicholas, Williams, Paul and Sandaradura, Indy (2020). Therapeutic drug monitoring of commonly used anti-infective agents: A nationwide cross-sectional survey of Australian hospital practices. International Journal of Antimicrobial Agents, 56 (6) 106180, 106180. doi: 10.1016/j.ijantimicag.2020.106180

Ceftriaxone dosing in patients admitted from the emergency department with sepsis

Heffernan, Aaron J., Curran, Rebecca A., Denny, Kerina J., Sime, Fekade B., Stanford, Claire L., McWhinney, Brett, Ungerer, Jacobus, Roberts, Jason A. and Lipman, Jeffrey (2020). Ceftriaxone dosing in patients admitted from the emergency department with sepsis. European Journal of Clinical Pharmacology, 77 (2), 207-214. doi: 10.1007/s00228-020-03001-z

The role of antibiotic pharmacokinetic studies performed post-licensing

Parker, Suzanne L., Abdul-Aziz, Mohd Hafiz and Roberts, Jason A. (2020). The role of antibiotic pharmacokinetic studies performed post-licensing. International Journal of Antimicrobial Agents, 56 (6) 106165, 106165. doi: 10.1016/j.ijantimicag.2020.106165

Pharmacodynamic Analysis of Meropenem and Fosfomycin Combination Against Carbapenem-Resistant in Patients with Normal Renal Clearance: Can It Be a Treatment Option?

Mohd Sazlly Lim, Sazlyna, Heffernan, Aaron J., Roberts, Jason A. and Sime, Fekade B. (2020). Pharmacodynamic Analysis of Meropenem and Fosfomycin Combination Against Carbapenem-Resistant in Patients with Normal Renal Clearance: Can It Be a Treatment Option?. Microbial drug resistance (Larchmont, N.Y.), 27 (4) mdr.2020.0197, 546-552. doi: 10.1089/mdr.2020.0197

Effectiveness of therapeutic drug monitoring guided vancomycin dosing in adult patients receiving extra corporeal membrane oxygenation

Marella, Prashanti, Roberts, Jason, Hay, Karen and Shekar, Kiran (2020). Effectiveness of therapeutic drug monitoring guided vancomycin dosing in adult patients receiving extra corporeal membrane oxygenation. Antimicrobial Agents and Chemotherapy, 64 (9) e01179-20. doi: 10.1128/aac.01179-20

Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae

Sumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Islam, Kamrul, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2020). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae. Journal of Antimicrobial Chemotherapy, 75 (9), 2633-2640. doi: 10.1093/jac/dkaa211

Physician drug prescribing preferences and availability for ventilation of patients with COVID-19

Coombes, Ian D., Dooley, Michael J., Townsend, Shane, Carmichael, Sinead, Poole, Susan G., Karamujic, Nermin, Richards, Brent, Ziegenfuss, Marc, Ankravs, Melissa J., Uren, Hailie, Roberts, Jason A. and Holley, Anthony (2020). Physician drug prescribing preferences and availability for ventilation of patients with COVID-19. Critical Care and Resuscitation, 22 (3), 271-274.

Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit

Economou, Caleb J. P., Ordoñez, Jennifer, Wallis, Steven C., Richards, Brent, McWhinney, Brett, Lipman, Jeffrey and Roberts, Jason A. (2020). Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit. International Journal of Antimicrobial Agents, 56 (3) 106058, 1-5. doi: 10.1016/j.ijantimicag.2020.106058

How to design a study to evaluate therapeutic drug monitoring in infectious diseases?

Märtson, A. G., Sturkenboom, M. G. G., Stojanova, J., Cattaneo, D., Hope, W., Marriott, D., Patanwala, A. E., Peloquin, C. A., Wicha, S. G., van der Werf, T. S., Tängdén, T., Roberts, J. A., Neely, M. N. and Alffenaar, J. W. C. (2020). How to design a study to evaluate therapeutic drug monitoring in infectious diseases?. Clinical Microbiology and Infection, 26 (8), 1008-1016. doi: 10.1016/j.cmi.2020.03.008

What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?

Cotta, Menino Osbert, Abdul-Aziz, Mohd Hafiz, Frey, Otto R., Sime, Fekade Bruck, Roberts, Jason A. and Roehr, Anka C. (2020). What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?. Therapeutic Drug Monitoring, 42 (4), 626-630. doi: 10.1097/ftd.0000000000000731

Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a comprehensive review by the PK/PD of anti-infectives study group of the European Society of Antimicrobial Agents

Zeitlinger, Markus, Koch, Birgit C. P., Bruggemann, Roger, De Cock, Pieter, Felton, Timothy, Hites, Maya, Le, Jennifer, Luque, Sonia, MacGowan, Alasdair P., Marriott, Deborah J. E., Muller, Anouk E., Nadrah, Kristina, Paterson, David L., Standing, Joseph F., Telles, João P., Wölfl-Duchek, Michael, Thy, Michael and Roberts, Jason A. (2020). Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a comprehensive review by the PK/PD of anti-infectives study group of the European Society of Antimicrobial Agents. Clinical Pharmacokinetics, 59 (10), 1195-1216. doi: 10.1007/s40262-020-00924-9

Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models

Dhaese, Sofie, Heffernan, Aaron, Liu, David, Abdul-Aziz, Mohd Hafiz, Stove, Veronique, Tam, Vincent H., Lipman, Jeffrey, Roberts, Jason A. and De Waele, Jan J. (2020). Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models. Clinical Pharmacokinetics, 59 (10), 1237-1250. doi: 10.1007/s40262-020-00919-6

The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial

Denholm, Justin T., Davis, Joshua, Paterson, David, Roberts, Jason, Morpeth, Susan, Snelling, Thomas, Zentner, Dominica, Rees, Megan, O'Sullivan, Matthew, Price, David, Bowen, Asha, Tong, Steven Y. C., Davis, Joshua, Denholm, Justin, Tong, Steven, ASCOT Investigator Group, Rees, Megan, Paterson, David, Price, David, Morpeth, Susan, O'Sullivan, Matthew, Roberts, Jason, Snelling, Thomas, Anderson, Sue, McQuilton, Zoe, Venkatesh, Bala, Hammond, Naomi, Jha, Vivekanend, Burston, Victoria John ... Slow, Sandy (2020). The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial. Trials, 21 (1) 646. doi: 10.1186/s13063-020-04576-9

Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model

Heffernan, Aaron J., Sime, Fekade B., Sarovich, Derek S., Neely, Michael, Guerra-Valero, Yarmarly, Naicker, Saiyuri, Cottrell, Kyra, Harris, Patrick, Andrews, Katherine T., Ellwood, David, Wallis, Steven C., Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2020). Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model. Antimicrobial Agents and Chemotherapy, 64 (9) e00879-20. doi: 10.1128/aac.00879-20

Towards precision medicine: therapeutic drug monitoring-guided dosing of vancomycin and β-lactam antibiotics to maximize effectiveness and minimize toxicity

Cusumano, Jaclyn A., Klinker, Kenneth P., Huttner, Angela, Luther, Megan K., Roberts, Jason A. and LaPlante, Kerry L. (2020). Towards precision medicine: therapeutic drug monitoring-guided dosing of vancomycin and β-lactam antibiotics to maximize effectiveness and minimize toxicity. American Journal of Health-System Pharmacy, 77 (14), 1104-1112. doi: 10.1093/ajhp/zxaa128

Kidney transplant recipient’s perceptions of blood testing through microsampling and venepuncture

Scuderi, Carla E., Parker, Suzanne L., Jacks, Margaret, John, George, McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Roberts, Jason A., Healy, Helen and Staatz, Christine E. (2020). Kidney transplant recipient’s perceptions of blood testing through microsampling and venepuncture. Bioanalysis, 12 (13) bio-2020-0057, 873-881. doi: 10.4155/bio-2020-0057

Comparative plasma pharmacokinetics of ceftriaxone and ertapenem between normoalbuminemia, hypoalbuminemia and with albumin replacement in a sheep model

Dhanani, Jayesh A., Ahern, Benjamin, Lupinsky, Liad, Jackson, Karen, Wallis, Steven C., Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2020). Comparative plasma pharmacokinetics of ceftriaxone and ertapenem between normoalbuminemia, hypoalbuminemia and with albumin replacement in a sheep model. Antimicrobial Agents and Chemotherapy, 64 (7). doi: 10.1128/aac.02584-19

Non-polymyxin based combinations as potential alternatives in treatment against carbapenem-resistant Acinetobacter baumannii infections

Mohd Sazlly Lim, S., Naicker, S., Ayfan, A. K., Zowawi, H., Roberts, J. A. and Sime, F. B. (2020). Non-polymyxin based combinations as potential alternatives in treatment against carbapenem-resistant Acinetobacter baumannii infections. International Journal of Antimicrobial Agents, 56 (4) 106115, 106115. doi: 10.1016/j.ijantimicag.2020.106115

What are the current approaches to optimising antimicrobial dosing in the intensive care unit?

Chai, Ming G., Cotta, Menino O., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2020). What are the current approaches to optimising antimicrobial dosing in the intensive care unit?. Pharmaceutics, 12 (7) 638, 1-22. doi: 10.3390/pharmaceutics12070638

Clinically relevant epithelial lining fluid concentrations of meropenem with ciprofloxacin provide synergistic killing and resistance suppression of hypermutable Pseudomonas aeruginosa in a dynamic biofilm model

Bilal, Hajira, Bergen, Phillip J., Tait, Jessica R., Wallis, Steven C., Peleg, Anton Y., Roberts, Jason A., Oliver, Antonio, Nation, Roger L. and Landersdorfer, Cornelia B. (2020). Clinically relevant epithelial lining fluid concentrations of meropenem with ciprofloxacin provide synergistic killing and resistance suppression of hypermutable Pseudomonas aeruginosa in a dynamic biofilm model. Antimicrobial Agents and Chemotherapy, 64 (7) e00469-20. doi: 10.1128/aac.00469-20

Conventional pig as animal model for human renal drug excretion processes: unravelling the porcine renal function by use of a cocktail of exogenous markers

Dhondt, Laura, Croubels, Siska, De Paepe, Peter, Wallis, Steven C., Pandey, Saurabh, Roberts, Jason A., Lipman, Jeffrey, De Cock, Pieter and Devreese, Mathias (2020). Conventional pig as animal model for human renal drug excretion processes: unravelling the porcine renal function by use of a cocktail of exogenous markers. Frontiers in Pharmacology, 11 883, 883. doi: 10.3389/fphar.2020.00883

Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study

De Bus, Liesbet, Depuydt, Pieter, Steen, Johan, Dhaese, Sofie, De Smet, Ken, Tabah, Alexis, Akova, Murat, Cotta, Menino Osbert, De Pascale, Gennaro, Dimopoulos, George, Fujitani, Shigeki, Garnacho-Montero, Jose, Leone, Marc, Lipman, Jeffrey, Ostermann, Marlies, Paiva, José-Artur, Schouten, Jeroen, Sjövall, Fredrik, Timsit, Jean-François, Roberts, Jason A., Zahar, Jean-Ralph, Zand, Farid, Zirpe, Kapil, De Waele, Jan J. and DIANA study group (2020). Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study. Intensive Care Medicine, 46 (7), 1404-1417. doi: 10.1007/s00134-020-06111-5

Principles of ethical prescribing for self and others: hydroxychloroquine in the COVID-19 pandemic

Coombes, Ian, Markwell, Alexandra, Kubler, Paul, Redmond, Andrew M., McGurk, Gordon and Roberts, Jason A. (2020). Principles of ethical prescribing for self and others: hydroxychloroquine in the COVID-19 pandemic. Australian Prescriber, 43 (3), 76-77. doi: 10.18773/austprescr.2020.030

Isolation and rapid sharing of the 2019 novel coronavirus (SARS-CoV-2) from the first patient diagnosed with COVID-19 in Australia

Caly, Leon, Druce, Julian, Roberts, Jason, Bond, Katherine, Tran, Thomas, Kostecki, Renata, Yoga, Yano, Naughton, William, Taiaroa, George, Seemann, Torsten, Schultz, Mark B, Howden, Benjamin P, Korman, Tony M, Lewin, Sharon R, Williamson, Deborah A and Catton, Mike G (2020). Isolation and rapid sharing of the 2019 novel coronavirus (SARS-CoV-2) from the first patient diagnosed with COVID-19 in Australia. Medical Journal of Australia, 212 (10), 459-462. doi: 10.5694/mja2.50569

Population pharmacokinetics and dosing recommendations of levetiracetam in adult and elderly patients with epilepsy

Hernández-Mitre, María Patricia, Medellín-Garibay, Susanna Edith, Rodríguez-Leyva, Ildefonso, Rodríguez-Pinal, Cristian Jazmín, Zarazúa, Sergio, Jung-Cook, Helgi Helene, Roberts, Jason A., Romano-Moreno, Silvia and Milán-Segovia, Rosa del Carmen (2020). Population pharmacokinetics and dosing recommendations of levetiracetam in adult and elderly patients with epilepsy. Journal of Pharmaceutical Sciences, 109 (6), 2070-2078. doi: 10.1016/j.xphs.2020.02.018

Low levels of salicylic acid and salicyluric acid are present in synovial fluid of patients taking aspirin at the time of knee arthroplasty surgery

Eisen, Damon P., McEwen, Peter, Hansen, Regina, Pandey, Saurabh, Wallis, Steven C. and Roberts, Jason A. (2020). Low levels of salicylic acid and salicyluric acid are present in synovial fluid of patients taking aspirin at the time of knee arthroplasty surgery. Clinical and Experimental Pharmacology and Physiology, 47 (9) 1440-1681.13333, 1635-1637. doi: 10.1111/1440-1681.13333

Optimization of flucloxacillin dosing regimens in critically ill patients using population pharmacokinetic modelling of total and unbound concentrations

Jager, Nynke G. L., van Hest, Reinier M., Xie, Jiao, Wong, Gloria, Ulldemolins, Marta, Brüggemann, Roger J. M., Lipman, Jeffrey and Roberts, Jason A. (2020). Optimization of flucloxacillin dosing regimens in critically ill patients using population pharmacokinetic modelling of total and unbound concentrations. Journal of Antimicrobial Chemotherapy, 75 (9), 2641-2649. doi: 10.1093/jac/dkaa187

An Integrated Dialysis Pharmacometric (IDP) model to evaluate the pharmacokinetics in patients undergoing renal replacement therapy

Broeker, Astrid, Vossen, Matthias G., Thalhammer, Florian, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Wicha, Sebastian G. (2020). An Integrated Dialysis Pharmacometric (IDP) model to evaluate the pharmacokinetics in patients undergoing renal replacement therapy. Pharmaceutical Research, 37 (6) 96, 96. doi: 10.1007/s11095-020-02832-w

Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#

Abdul-Aziz, Mohd H., Alffenaar, Jan-Willem C., Bassetti, Matteo, Bracht, Hendrik, Dimopoulos, George, Marriott, Deborah, Neely, Michael N., Paiva, Jose-Artur, Pea, Federico, Sjovall, Fredrik, Timsit, Jean F., Udy, Andrew A., Wicha, Sebastian G., Zeitlinger, Markus, De Waele, Jan J., Roberts, Jason A., the Infection Section of European Society of Intensive Care Medicine (ESICM), Pharmacokinetic/pharmacodynamic and Critically Ill Patient Study Groups of European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Group of International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) and Infections in the ICU and Sepsis Working Group of International Society of Antimicrobial Chemotherapy (ISAC) (2020). Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#. Intensive Care Medicine, 46 (6), 1127-1153. doi: 10.1007/s00134-020-06050-1

Pharmacokinetics of sulfamethoxazole and trimethoprim during veno-venous extracorporeal membrane oxygenation: a case report

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2020). Pharmacokinetics of sulfamethoxazole and trimethoprim during veno-venous extracorporeal membrane oxygenation: a case report. Pharmacotherapy, 40 (7) phar.2413, 713-717. doi: 10.1002/phar.2413

Oral fosfomycin treatment for enterococcal urinary tract infections in a dynamic in vitro model

Abbott, Iain J., van Gorp, Elke, van der Meijden, Aart, Wijma, Rixt A., Meletiadis, Joseph, Roberts, Jason A., Mouton, Johan W. and Peleg, Anton Y. (2020). Oral fosfomycin treatment for enterococcal urinary tract infections in a dynamic in vitro model. Antimicrobial Agents and Chemotherapy, 64 (6) e00342-20. doi: 10.1128/aac.00342-20

On-site therapeutic drug monitoring

Ates, H. Ceren, Roberts, Jason A., Lipman, Jeffrey, Cass, Anthony E.G., Urban, Gerald A. and Dincer, Can (2020). On-site therapeutic drug monitoring. Trends in Biotechnology, 38 (11), 1262-1277. doi: 10.1016/j.tibtech.2020.03.001

Correction to: Ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria: understanding nebulization of aminoglycosides and colistin (Intensive Care Medicine, (2020), 46, 4, (766-770), 10.1007/s00134-019-05890-w)

Rouby, J. J., Sole-Lleonart, C., Rello, J., Monsel, Antoine, Constantin, Jean-Michel, Bouglé, Adrien, Blot, Stijn, Poulakou, Garyphalia, Pontikis, Konstantinos, Kyriakoudi, Anna, Koutsoukou, Antonia, Dimopoulos, George, Routsi, Christina, Arvaniti, Kostoula, Pereira, Jose Manuel, Felton, Timothy, Dhanani, Jayesh, Roberts, Jason, Bassetti, Matteo, Welte, Tobias, Dugernier, Jonathan, Laterre, Pierre-François, Ehrmann, Stephan, Boisson, Matthieu, Mimoz, Olivier, Leone, Marc, Palmer, Lucy B., Pugin, Jérôme, Qu, Jie-ming ... Liao, Xuelian (2020). Correction to: Ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria: understanding nebulization of aminoglycosides and colistin (Intensive Care Medicine, (2020), 46, 4, (766-770), 10.1007/s00134-019-05890-w). Intensive Care Medicine, 46 (4), 766-770. doi: 10.1007/s00134-020-05986-8

Corrigendum to “Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients: a prospective observational study” [Journal of Critical Care 52 (2019) 75–79]

Dhaese, Sofie A. M., Thooft, Alexander D. J., Farkas, Andras, Lipman, Jeffrey, Verstraete, Alain G., Stove, Veronique, Roberts, Jason A. and De Waele, Jan J. (2020). Corrigendum to “Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients: a prospective observational study” [Journal of Critical Care 52 (2019) 75–79]. Journal of Critical Care, 56, 325-325. doi: 10.1016/j.jcrc.2019.09.020

Prophylactic cefazolin dosing in women with body mass index >35 kg·m−2 undergoing cesarean delivery : a pharmacokinetic study of plasma and interstitial fluid

Eley, Victoria A., Christensen, Rebecca, Ryan, Rochelle, Jackson, Dwane, Parker, Suzanne L., Smith, Matthew, van Zundert, Andre A., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Prophylactic cefazolin dosing in women with body mass index >35 kg·m−2 undergoing cesarean delivery : a pharmacokinetic study of plasma and interstitial fluid. Anesthesia and Analgesia, 131 (1), 1-207. doi: 10.1213/ane.0000000000004766

The Effect of Renal Replacement Therapy and Antibiotic Dose on Antibiotic Concentrations in Critically Ill Patients: Data From the Multinational Sampling Antibiotics in Renal Replacement Therapy Study

Roberts, Jason A., Joynt, Gavin M., Lee, Anna, Choi, Gordon, Bellomo, Rinaldo, Kanji, Salmaan, Mudaliar, M Yugan, Peake, Sandra L., Stephens, Dianne, Taccone, Fabio Silvio, Ulldemolins, Marta, Valkonen, Miia Maaria, Agbeve, Julius, Baptista, João P., Bekos, Vasileios, Boidin, Clement, Brinkmann, Alexander, Buizen, Luke, Castro, Pedro, Cole, C. Louise, Creteur, Jacques, De Waele, Jan J., Deans, Renae, Eastwood, Glenn M., Escobar, Leslie, Gomersall, Charles, Gresham, Rebecca, Jamal, Janattul Ain, Kluge, Stefan ... Young, Helen (2020). The Effect of Renal Replacement Therapy and Antibiotic Dose on Antibiotic Concentrations in Critically Ill Patients: Data From the Multinational Sampling Antibiotics in Renal Replacement Therapy Study. Clinical Infectious Diseases, 72 (8), 1369-1378. doi: 10.1093/cid/ciaa224

Development of Population and Bayesian Models for Applied Use in Patients Receiving Cefepime

Liu, Jiajun, Neely, Michael, Lipman, Jeffrey, Sime, Fekade, Roberts, Jason A., Kiel, Patrick J., Avedissian, Sean N., Rhodes, Nathaniel J. and Scheetz, Marc H. (2020). Development of Population and Bayesian Models for Applied Use in Patients Receiving Cefepime. Clinical Pharmacokinetics, 59 (8), 1027-1036. doi: 10.1007/s40262-020-00873-3

Amoxicillin-clavulanate dosing in the intensive care unit: the additive effect of renal replacement therapy in a patient with normal kidney function

Lonsdale, Dagan Osborne, Lipman, Jeffrey, Livermore, Amelia, McWhinney, Brett, Ungerer, Jacobus P.J. and Roberts, Jason A. (2020). Amoxicillin-clavulanate dosing in the intensive care unit: the additive effect of renal replacement therapy in a patient with normal kidney function. Chemotherapy, 64 (4), 1-4. doi: 10.1159/000505057

Evaluation of target attainment of oral posaconazole suspension in immunocompromised children

Lai, Tony, Alffenaar, Jan-Willem, Kesson, Alison, Bandodkar, Sushil and Roberts, Jason A. (2020). Evaluation of target attainment of oral posaconazole suspension in immunocompromised children. Journal of Antimicrobial Chemotherapy, 75 (3), 726-729. doi: 10.1093/jac/dkz481

β-lactam antibiotic versus combined β-lactam antibiotic and single-daily dosing regimens of aminoglycosides for the treatment of serious infections: a meta-analysis

Heffernan, Aaron James, Sime, Fekade Bruck, Sun, Jing, Lipman, Jeffrey, Kumar, Anand, Andrews, Katherine, Ellwood, David, Grimwood, Keith and Roberts, Jason (2020). β-lactam antibiotic versus combined β-lactam antibiotic and single-daily dosing regimens of aminoglycosides for the treatment of serious infections: a meta-analysis. International Journal of Antimicrobial Agents, 55 (3) 105839, 105839. doi: 10.1016/j.ijantimicag.2019.10.020

Finding the relevance of antimicrobial stewardship for cystic fibrosis

Cogen, Jonathan D., Kahl, Barbara C., Maples, Holly, McColley, Susanna A., Roberts, Jason A., Winthrop, Kevin L., Morris, Andrew M., Holmes, Alison, Flume, Patrick A., VanDevanter, Donald R., Waters, Valerie, Muhlebach, Marianne S., Elborn, J. Stuart, Saiman, Lisa and Bell, Scott C. (2020). Finding the relevance of antimicrobial stewardship for cystic fibrosis. Journal of Cystic Fibrosis, 19 (4), 511-520. doi: 10.1016/j.jcf.2020.02.012

The challenge of quantifying and managing pharmacokinetic variability of beta-lactams in the critically ill

Crass, Ryan L., Williams, Paul and Roberts, Jason A. (2020). The challenge of quantifying and managing pharmacokinetic variability of beta-lactams in the critically ill. Anaesthesia Critical Care and Pain Medicine, 39 (1), 27-29. doi: 10.1016/j.accpm.2019.12.008

β-Lactam pharmacodynamics in Gram-negative bloodstream infections in the critically ill

Wong, Gloria, Taccone, Fabio, Villois, Paola, Scheetz, Marc H., Rhodes, Nathaniel J., Briscoe, Scott, McWhinney, Brett, Nunez-Nunez, Maria, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A. (2020). β-Lactam pharmacodynamics in Gram-negative bloodstream infections in the critically ill. Journal of Antimicrobial Chemotherapy, 75 (2), 429-433. doi: 10.1093/jac/dkz437

Oral fosfomycin efficacy with variable urinary exposures following single and multiple doses against Enterobacterales: the importance of heteroresistance on growth outcome

Abbott, Iain J., van Gorp, Elke, Wijma, Rixt A., Meletiadis, Joseph, Roberts, Jason A., Mouton, Johan W. and Peleg, Anton Y. (2020). Oral fosfomycin efficacy with variable urinary exposures following single and multiple doses against Enterobacterales: the importance of heteroresistance on growth outcome. Antimicrobial Agents and Chemotherapy, 64 (3) e01982-19. doi: 10.1128/aac.01982-19

A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration. Antimicrobial Agents and Chemotherapy, 64 (1) e01655. doi: 10.1128/aac.01655-19

Linguistic and cultural adaptation to the Portuguese language of antimicrobial dose adjustment software

Silva, Samuel Dutra da, Alves, Geisa Cristina da Silva, Chequer, Farah Maria Drumond, Farkas, Andras, Daróczi, Gergely, Roberts, Jason A. and Sanches, Cristina (2020). Linguistic and cultural adaptation to the Portuguese language of antimicrobial dose adjustment software. Einstein (São Paulo), 18, 1-8. doi: 10.31744/einstein_journal/2020ao5023

Meropenem-tobramycin combination regimens combat carbapenem-resistant Pseudomonas aeruginosa in the hollow-fiber infection model simulating augmented renal clearance in critically ill patients

Yadav, Rajbharan, Bergen, Phillip J., Rogers, Kate E., Kirkpatrick, Carl M. J., Wallis, Steven C., Huang, Yuling, Bulitta, Jürgen B., Paterson, David L., Lipman, Jeffrey, Nation, Roger L., Roberts, Jason A. and Landersdorfer, Cornelia B. (2020). Meropenem-tobramycin combination regimens combat carbapenem-resistant Pseudomonas aeruginosa in the hollow-fiber infection model simulating augmented renal clearance in critically ill patients. Antimicrobial Agents and Chemotherapy, 64 (1) e01679-19. doi: 10.1128/aac.01679-19

Pharmacokinetic/pharmacodynamic adequacy of polymyxin B against extensively drug-resistant Gram-negative bacteria in critically ill, general ward and cystic fibrosis patient populations

Xie, Jiao, Roberts, Jason A., Lipman, Jeffrey, Cai, Yan, Wang, Haitao, Zhao, Nuannuan, Xu, Xiaona, Yang, Shan, Li, Youjia and Zhang, Kanghuai (2020). Pharmacokinetic/pharmacodynamic adequacy of polymyxin B against extensively drug-resistant Gram-negative bacteria in critically ill, general ward and cystic fibrosis patient populations. International Journal of Antimicrobial Agents, 55 (6) 105943, 105943. doi: 10.1016/j.ijantimicag.2020.105943

Software for dose adjustment of antimicrobials. Implications for plasma concentrations and pratical limitations

Alves, Geisa Cristina da Silva, Silva, Samuel Dutra da, Chequer, Farah Maria Drumond, Castro, Whocely Victor de, Baldoni, André Oliveira, Farkas, Andras, Daróczi, Gergely, Roberts, Jason Alexander and Sanches, Cristina (2020). Software for dose adjustment of antimicrobials. Implications for plasma concentrations and pratical limitations. Einstein, 18, 1-2. doi: 10.31744/einstein_journal/2020ce5858

The pharmacokinetics of meropenem and piperacillin-tazobactam during sustained low efficiency haemodiafiltration (SLED-HDF)

Donnellan, Sine, Wright, Daniel F. B., Roberts, Jason A., Duffull, Stephen B., Schollum, John B. W., Putt, Tracey L., Wallis, Steven C. and Walker, Robert J. (2020). The pharmacokinetics of meropenem and piperacillin-tazobactam during sustained low efficiency haemodiafiltration (SLED-HDF). European Journal of Clinical Pharmacology, 76 (2), 239-247. doi: 10.1007/s00228-019-02792-0

Ceftolozane–tazobactam in an elastomeric infusion device for ambulatory care: an in vitro stability study

Raby, Edward, Naicker, Saiyuri, Sime, Fekade Bruck, Manning, Laurens, Wallis, Steven C., Pandey, Saurabh and Roberts, Jason A. (2019). Ceftolozane–tazobactam in an elastomeric infusion device for ambulatory care: an in vitro stability study. European Journal of Hospital Pharmacy, 27 (e1) e19002093, e84-e86. doi: 10.1136/ejhpharm-2019-002093

Linezolid dosing in patients with liver cirrhosis: standard dosing risk toxicity

Luque, Sonia, Muñoz-Bermudez, Rosana, Echeverría-Esnal, Daniel, Sorli, Luisa, Campillo, Nuria, Martínez-Casanova, Javier, González-Colominas, Elena, Álvarez-Lerma, Francisco, Horcajada, Juan Pablo, Grau, Santiago and Roberts, Jason A. (2019). Linezolid dosing in patients with liver cirrhosis: standard dosing risk toxicity. Therapeutic Drug Monitoring, 41 (6), 732-739. doi: 10.1097/FTD.0000000000000665

Pharmacokinetics and pharmacodynamics of anti-infective agents during continuous veno-venous hemofiltration in critically ill patients: lessons learned from an ancillary study of the IVOIRE trial

Breilh, Dominique, Honore, Patrick M., De Bels, David, Roberts, Jason A., Gordien, Jean Baptiste, Fleureau, Catherine, Dewitte, Antoine, Coquin, Julien, Roze, Hadrien, Perez, Paul, Attou, Rachid, Redant, Sebastien, Kugener, Luc, Saux, Marie-Claude, Spapen, Herbert D., Ouattare, Alexandre and Joannes-Boyau, Olivier (2019). Pharmacokinetics and pharmacodynamics of anti-infective agents during continuous veno-venous hemofiltration in critically ill patients: lessons learned from an ancillary study of the IVOIRE trial. Journal of Translational Internal Medicine, 7 (4), 155-169. doi: 10.2478/jtim-2019-0031

Pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN)

Ranganathan, Dwarakanathan, Abdul-Aziz, Mohd H., John, George T., McWhinney, Brett C., Fassett, Robert G., Healy, Helen, Kubler, Paul, Lim, Aaron, Lipman, Jeffrey, Purvey, Megan, Roberts, Matthew, Reyaldeen, Reza, Ungerer, Jacobus and Roberts, Jason A. (2019). Pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN). Therapeutic Drug Monitoring, 41 (6), 703-713. doi: 10.1097/ftd.0000000000000658

Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion

Dhaese, S.A.M., Colin, P., Willems, H., Heffernan, A., Gadeyne, B., Van Vooren, S., Depuydt, P., Hoste, E., Stove, V., Verstraete, A.G., Lipman, J., Roberts, J.A. and De Waele, J.J. (2019). Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion. International Journal of Antimicrobial Agents, 54 (6), 741-749. doi: 10.1016/j.ijantimicag.2019.08.024

Update in antibiotic therapy in intensive care unit: report from the 2019 Nîmes International Symposium

Leone, Marc, Roberts, Jason A., Bassetti, Matteo, Bouglé, Adrien, Lavigne, Jean-Philippe, Legrand, Matthieu, Neely, Michael, Paiva, José-Artur, Payen, Didier, Rello, Jordi, Roger, Claire, Sjövall, Fredrik and Jung, Boris (2019). Update in antibiotic therapy in intensive care unit: report from the 2019 Nîmes International Symposium. Anaesthesia Critical Care and Pain Medicine, 38 (6), 647-656. doi: 10.1016/j.accpm.2019.09.009

Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP)

Tabah, Alexis, Bassetti, Matteo, Kollef, Marin H., Zahar, Jean-Ralph, Paiva, José-Artur, Timsit, Jean-Francois, Roberts, Jason A., Schouten, Jeroen, Giamarellou, Helen, Rello, Jordi, De Waele, Jan, Shorr, Andrew F., Leone, Marc, Poulakou, Garyphallia, Depuydt, Pieter and Garnacho-Montero, Jose (2019). Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP). Intensive Care Medicine, 46 (2), 245-265. doi: 10.1007/s00134-019-05866-w

Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter?

Abdul-Aziz, Mohd H. and Roberts, Jason A. (2019). Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter?. Current Opinion in Anaesthesiology, 33 (1), 1-82. doi: 10.1097/aco.0000000000000810

A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2019). A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study. Analytical and Bioanalytical Chemistry, 411 (29), 7831-7840. doi: 10.1007/s00216-019-02184-4

Attainment of therapeutic vancomycin level within the first 24 h: authors' response

Baptista, João Pedro, Roberts, Jason A., Sousa, Eduardo, Freitas, Ricardo, Devesa, Nuno and Pimentel, Jorge (2019). Attainment of therapeutic vancomycin level within the first 24 h: authors' response. Critical Care, 23 (1) 354, 354. doi: 10.1186/s13054-019-2639-7

Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study

Pandey, Saurabh, Dhanani, Jayesh, Lipman, Jeffrey, Roberts, Jason A., Wallis, Steve C. and Parker, Suzanne L. (2019). Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study. Clinical Chemistry and Laboratory Medicine, 58 (2), 274-284. doi: 10.1515/cclm-2019-0780

Amikacin initial dose in critically ill patients: a nonparametric approach to optimize a priori pharmacokinetic/pharmacodynamic target attainments in individual patients

Boidin, Clément, Bourguignon, Laurent, Cohen, Sabine, Roger, Claire, Lefrant, Jean-Yves, Roberts, Jason A., Allaouchiche, Bernard, Lepape, Alain, Friggeri, Arnaud and Goutelle, Sylvain (2019). Amikacin initial dose in critically ill patients: a nonparametric approach to optimize a priori pharmacokinetic/pharmacodynamic target attainments in individual patients. Antimicrobial Agents and Chemotherapy, 63 (11) e00993-19, e00993-19. doi: 10.1128/aac.00993-19

Pharmacokinetics of total and unbound cefazolin during veno-arterial extracorporeal membrane oxygenation: a case report

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2019). Pharmacokinetics of total and unbound cefazolin during veno-arterial extracorporeal membrane oxygenation: a case report. Chemotherapy, 64 (3), 1-4. doi: 10.1159/000502474

Pharmacokinetics of flucloxacillin during prolonged intermittent renal replacement therapy in a 76-year-old man

Fox, Emma, Cheng, Vesa, Rawlins, Matthew, Dyer, John, De Keulenaer, Bart, Page, Michael M., Hoad, Kirsten and Roberts, Jason (2019). Pharmacokinetics of flucloxacillin during prolonged intermittent renal replacement therapy in a 76-year-old man. Journal of Chemotherapy, 31 (7-8), 1-5. doi: 10.1080/1120009X.2019.1681622

Antimicrobial therapy during ECMO – customised dosing with therapeutic drug monitoring: the way to go?

Abdul-Aziz, Mohd H., Shekar, Kiran and Roberts, Jason A. (2019). Antimicrobial therapy during ECMO – customised dosing with therapeutic drug monitoring: the way to go?. Anaesthesia Critical Care and Pain Medicine, 38 (5), 451-453. doi: 10.1016/j.accpm.2019.07.005

The global prevalence of multidrug-resistance among Acinetobacter baumannii causing hospital-acquired and ventilator-associated pneumonia and its associated mortality: A systematic review and meta-analysis

Mohd Sazlly, Lim S, Zainal Abidin, A., Liew, S.M., Roberts, J.A. and Sime, FB (2019). The global prevalence of multidrug-resistance among Acinetobacter baumannii causing hospital-acquired and ventilator-associated pneumonia and its associated mortality: A systematic review and meta-analysis. Journal of Infection, 79 (6), 593-600. doi: 10.1016/j.jinf.2019.09.012

Reducing post-caesarean delivery surgical site infections: a narrative review

Douville, S. E., Callaway, L. K., Amoako, A., Roberts, J. and Eley, V. A. (2019). Reducing post-caesarean delivery surgical site infections: a narrative review. International Journal of Obstetric Anesthesia, 42, 76-86. doi: 10.1016/j.ijoa.2019.08.007

Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients (vol 51, pg 594, 2018)

Dhaese, Sofie A. M., Roberts, Jason A., Carlier, Mieke, Verstraete, Alain G., Stove, Veronique and De Waele, Jan J. (2019). Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients (vol 51, pg 594, 2018). International Journal of Antimicrobial Agents, 54 (3), 380-380. doi: 10.1016/j.ijantimicag.2019.07.022

Population pharmacokinetics of periarticular ketorolac in adult patients undergoing total hip or total knee replacement surgery

Gurunathan, Usha, Parker, Suzanne L., Maguire, Richard, Ramdath, Dale, Bijoor, Manu, Wallis, Steven C. and Roberts, Jason A. (2019). Population pharmacokinetics of periarticular ketorolac in adult patients undergoing total hip or total knee replacement surgery. Anesthesia and Analgesia, 129 (3), 701-708. doi: 10.1213/ANE.0000000000003377

Vancomycin population pharmacokinetics in critically ill adults during sustained low-efficiency dialysis

Kanji, Salmaan, Roberts, Jason A., Xie, Jiao, Zelenitsky, Sheryl, Hiremath, Swapnil, Zhang, Guijun, Watpool, Irene, Porteous, Rebecca and Patel, Rakesh (2019). Vancomycin population pharmacokinetics in critically ill adults during sustained low-efficiency dialysis. Clinical Pharmacokinetics, 59 (3), 327-334. doi: 10.1007/s40262-019-00817-6

Augmented renal clearance: A real phenomenon with an uncertain cause

Baptista, João Pedro, Roberts, Jason A. and Udy, Andrew A. (2019). Augmented renal clearance: A real phenomenon with an uncertain cause. Anaesthesia Critical Care and Pain Medicine, 38 (4), 335-336. doi: 10.1016/j.accpm.2019.03.002

Corrigendum to ‘Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients’ (International Journal of Antimicrobial Agents (2018) 51(4) (594–600), (S0924857917304491), (10.1016/j.ijantimicag.2017.12.015))

Dhaese, Sofie A.M., Roberts, Jason A., Carlier, M., Verstraete, Alain G., Stove, Veronique and DeWaele, J. J. (2019). Corrigendum to ‘Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients’ (International Journal of Antimicrobial Agents (2018) 51(4) (594–600), (S0924857917304491), (10.1016/j.ijantimicag.2017.12.015)). International Journal of Antimicrobial Agents, 54 (2), 271-271. doi: 10.1016/j.ijantimicag.2019.07.007

Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients: a prospective observational study

Dhaese, Sofie A.M., Thooft, Alexander D.J., Farkas, Andras, Lipman, Jeffrey, Verstraete, Alain G., Stove, Veronique, Roberts, Jason A. and De Waele, Jan J. (2019). Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients: a prospective observational study. Journal of Critical Care, 52, 75-79. doi: 10.1016/j.jcrc.2019.04.013

In-vitro adsorption and sieving coefficient of ticarcillin-clavulanate during continuous haemofiltration

T.P. Wan, Winnie, Guerra Valero, Yarmarly, Choi, Gordon Y.S., Ordóñez Mejia, Jenny L., Wallis, Steven C., Joynt, Gavin M., Lipman, Jeffrey, Gomersall, Charles D. and Roberts, Jason A. (2019). In-vitro adsorption and sieving coefficient of ticarcillin-clavulanate during continuous haemofiltration. International Journal of Antimicrobial Agents, 54 (2), 261-264. doi: 10.1016/j.ijantimicag.2019.03.018

Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2019). Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction. Antimicrobial Agents and Chemotherapy, 63 (10) e01265-19. doi: 10.1128/aac.01265-19

What antibiotic exposures are required to suppress the emergence of resistance for gram‑negative bacteria? A systematic review

Sumi, Chandra Datta, Heffernan, Aaron J., Lipman, Jeffery, Roberts, Jason A. and Sime, Fekade B. (2019). What antibiotic exposures are required to suppress the emergence of resistance for gram‑negative bacteria? A systematic review. Clinical Pharmacokinetics, 58 (11), 1407-1443. doi: 10.1007/s40262-019-00791-z

Evaluation of pharmacokinetic/pharmacodynamic and clinical outcomes with 6-hourly empiric piperacillin-tazobactam dosing in hematological malignancy patients with febrile neutropenia

Weber, Nicholas, Jackson, Kathryn, McWhinney, Brett, Ungerer, Jacobus, Kennedy, Glen, Lipman, Jeffrey and Roberts, Jason A. (2019). Evaluation of pharmacokinetic/pharmacodynamic and clinical outcomes with 6-hourly empiric piperacillin-tazobactam dosing in hematological malignancy patients with febrile neutropenia. Journal of Infection and Chemotherapy, 25 (7), 503-508. doi: 10.1016/j.jiac.2019.02.014

Pharmacokinetics of benzylpenicillin (penicillin G) during prolonged intermittent renal replacement therapy

Cheng, Vesa, Rawlins, Matthew, Chang, Tim, Fox, Emma, Dyer, John, Allen, Chris, Litton, Edward, Page, Michael M., Hoad, Kirsten and Roberts, Jason A. (2019). Pharmacokinetics of benzylpenicillin (penicillin G) during prolonged intermittent renal replacement therapy. Chemotherapy, 64 (1), 1-5. doi: 10.1159/000499375

Population pharmacokinetics of ticarcillin in critically ill patients receiving extended daily diafiltration

Economou, Caleb J. P., Xie, Jiao, Comadira, Gregory, Richards, Brent, Tallott, Mandy, Wallis, Steven C., Ordoñez, Jenny, Lipman, Jeffrey and Roberts, Jason A. (2019). Population pharmacokinetics of ticarcillin in critically ill patients receiving extended daily diafiltration. International Journal of Antimicrobial Agents, 54 (3), 351-355. doi: 10.1016/j.ijantimicag.2019.06.027

Implementasi Antimicrobial Stewardship Program di Kawasan Asia: Sebuah Kajian Sistematis

Setiawan, Eko, Wibowo, Yosi I., Setiadi, Adji P., Nurpatria, Yul'aini, Sosilya, Hernycane, Wardhani, Dian K., Cotta, Menino O., Abdul-Aziz, Mohd-Hafiz and Roberts, Jason (2019). Implementasi Antimicrobial Stewardship Program di Kawasan Asia: Sebuah Kajian Sistematis. Indonesian Journal of Clinical Pharmacy, 8 (2), 141-156. doi: 10.15416/ijcp.2019.8.2.141

Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients

Sime, Fekade B., Byrn, Catherine J., Parker, Suzanne, Stuart, Janine, Butler, Jenie, Starr, Therese, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffery and Roberts, Jason A. (2019). Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients. Critical Care, 23 (1) 205, 205. doi: 10.1186/s13054-019-2483-9

Therapeutic drug monitoring-based dose optimisation of piperacillin/tazobactam to improve outcome in patients with sepsis (TARGET): a prospective, multi-centre, randomised controlled trial

Hagel, Stefan, Fiedler, Sandra, Hohn, Andreas, Brinkmann, Alexander, Frey, Otto R., Hoyer, Heike, Schlattmann, Peter, Kiehntopf, Michael, Roberts, Jason A., Pletz, Mathias W., Bloos, Frank, Angermair, Stefan, Bracht, Hendrik, Barth, Eberhard, Kluge, Stefan, Nierhaus, Axel, Motsch, Johann, Brenner, Thorsten, Annecke, Thorsten, Bach, Friedhelm, Weigand, Markus, Schappacher, Markus, Von Ameln-Mayerhofer, Andreas, Michels, Guido, Roehr, Anka, Fuchs, Thomas, Eichner, Sarah, Köng, Christina, Pinder, Nadine ... Braune, Anke (2019). Therapeutic drug monitoring-based dose optimisation of piperacillin/tazobactam to improve outcome in patients with sepsis (TARGET): a prospective, multi-centre, randomised controlled trial. Trials, 20 (1) 330, 330. doi: 10.1186/s13063-019-3437-x

Nebulized tranexamic acid therapy for hemoptysis associated with submassive pulmonary embolism

Dhanani, Jayesh A., Roberts, Jason and Reade, Michael C (2019). Nebulized tranexamic acid therapy for hemoptysis associated with submassive pulmonary embolism. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 32 (1) jamp.2019.1534, 12-14. doi: 10.1089/jamp.2019.1534

Defining optimal dosing of ciprofloxacin in patients with septic shock

Roberts, Jason A., Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Sjövall, Fredrik (2019). Defining optimal dosing of ciprofloxacin in patients with septic shock. Journal of Antimicrobial Chemotherapy, 74 (6) dkz069, 1662-1669. doi: 10.1093/jac/dkz069

Multidrug-resistant Acinetobacter baumannii infections: current evidence on treatment options and role of PK/PD in dose optimization

Lim, Sazlyna Mohd Sazlly, Sime, Fekade Bruck and Roberts, Jason (2019). Multidrug-resistant Acinetobacter baumannii infections: current evidence on treatment options and role of PK/PD in dose optimization. International Journal of Antimicrobial Agents, 53 (6), 726-745. doi: 10.1016/j.ijantimicag.2019.02.016

Obesity in the critically ill: a narrative review

Schetz, Miet, De Jong, Audrey, Deane, Adam M., Druml, Wilfried, Hemelaar, Pleun, Pelosi, Paolo, Pickkers, Peter, Reintam-Blaser, Annika, Roberts, Jason, Sakr, Yasser and Jaber, Samir (2019). Obesity in the critically ill: a narrative review. Intensive Care Medicine, 45 (6), 757-769. doi: 10.1007/s00134-019-05594-1

Pharmacokinetics of micafungin in critically ill patients receiving continuous venovenous hemodialysis with high cutoff membranes

Tenorio-Cañamás, Teresa, Grau, Santiago, Luque, Sonia, Fortún, Jesús, Liaño, Fernando and Roberts, Jason A. (2019). Pharmacokinetics of micafungin in critically ill patients receiving continuous venovenous hemodialysis with high cutoff membranes. Therapeutic Drug Monitoring, 41 (3), 376-382. doi: 10.1097/FTD.0000000000000595

Vancomycin pharmacokinetics throughout life: results from a pooled population analysis and evaluation of current dosing recommendations

Colin, Pieter J., Allegaert, Karel, Thomson, Alison H., Touw, Daan J., Dolton, Michael, de Hoog, Matthijs, Roberts, Jason A., Adane, Eyob D., Yamamoto, Masato, Santos-Buelga, Dolores, Martín-Suarez, Ana, Simon, Nicolas, Taccone, Fabio S., Lo, Yoke-Lin, Barcia, Emilia, Struys, Michel M. R. F. and Eleveld, Douglas J. (2019). Vancomycin pharmacokinetics throughout life: results from a pooled population analysis and evaluation of current dosing recommendations. Clinical Pharmacokinetics, 58 (6), 767-780. doi: 10.1007/s40262-018-0727-5

Vancomycin population pharmacokinetics for adult patients with sepsis or septic shock: are current dosing regimens sufficient?

Heffernan, A. J., Germano, A., Sime, F. B., Roberts, Jason A. and Kimura, E. (2019). Vancomycin population pharmacokinetics for adult patients with sepsis or septic shock: are current dosing regimens sufficient?. European Journal of Clinical Pharmacology, 75 (9), 1219-1226. doi: 10.1007/s00228-019-02694-1

Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study

Guerra Valero, Yarmarly C., Roberts, Jason A., Lipman, Jeffrey, Fourie, Cheryl, Starr, Therese, Wallis, Steven C. and Parker, Suzanne L. (2019). Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study. Journal of Pharmaceutical and Biomedical Analysis, 169, 288-292. doi: 10.1016/j.jpba.2019.03.018

Dexmedetomidine prescribing in Australian intensive care units: an observational study

O'Brien, Daniel W., Cotta, Menino O., Choo, Lyn, Fowler, Stephen, Downey, Maria, Fisquet, Stephanie, Tan, Ivy and Roberts, Jason A. (2019). Dexmedetomidine prescribing in Australian intensive care units: an observational study. Journal of Pharmacy Practice and Research, 49 (5) jppr.1529, 477-481. doi: 10.1002/jppr.1529

Antibiotic exposure at the site of infection: principles and assessment of tissue penetration

Jager, Nynke G. L., van Hest, Reinier M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2019). Antibiotic exposure at the site of infection: principles and assessment of tissue penetration. Expert Review of Clinical Pharmacology, 12 (7), 623-634. doi: 10.1080/17512433.2019.1621161

Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model

Dhanani, Jayesh A., Diab, Sara, Chaudhary, Jivesh, Cohen, Jeremy, Parker, Suzanne L., Wallis, Steven C., Boidin, Clément, Barnett, Adrian, Chew, Michelle, Roberts, Jason A. and Fraser, John F. (2019). Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model. Anesthesiology, 131 (2), 1-355. doi: 10.1097/ALN.0000000000002752

Personalized antibiotic dosing for the critically ill

Roberts, Jason A., Roger, Claire and De Waele, Jan J. (2019). Personalized antibiotic dosing for the critically ill. Intensive Care Medicine, 45 (5), 715-718. doi: 10.1007/s00134-019-05522-3

Narrative study on pharmacokinetics of antibiotics among critically ill patients: the implication on the pharmacokinetics-pharmacodynamics target attainment

Setiawan, Eko, Widyati, Marpaung, Ferdy Royland, Sukandar, Edy, Susaniwati, Lukas, Dwi Lily, Wijono, Heru, Warindra, Taufin, Kurniawan, Roni, Wibowo, Tjipto, Hendradi, Wahyu, Cotta, Menino Osbert, Abdul-Aziz, Mohd-Hafiz and Roberts, Jason (2019). Narrative study on pharmacokinetics of antibiotics among critically ill patients: the implication on the pharmacokinetics-pharmacodynamics target attainment. Pharmaceutical Sciences and Research, 6 (1). doi: 10.7454/psr.v6i1.4274

Effect of plasmapheresis on ATG (Thymoglobulin) clearance prior to adoptive T cell transfer

Zhang, Ping, Curley, Cameron I., Mudie, Kari, Nakagaki, Midori, Hill, Geoffrey R., Roberts, Jason A. and Tey, Siok-Keen (2019). Effect of plasmapheresis on ATG (Thymoglobulin) clearance prior to adoptive T cell transfer. Bone Marrow Transplantation, 54 (12), 2110-2116. doi: 10.1038/s41409-019-0505-5

A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III

Lipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino O., Davis, Joshua S., Finfer, Simon, Glass, Parisa, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Billot, Laurent and Dulhunty, Joel M. (2019). A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III. Critical Care and Resuscitation, 21 (1), 63-68.

Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review

Heffernan, Aaron J., Sime, Fekade B., Lipman, Jeffrey, Dhanani, Jayesh, Andrews, Katherine, Ellwood, David, Grimwood, Keith and Roberts, Jason A. (2019). Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review. International Journal of Antimicrobial Agents, 53 (3), 234-245. doi: 10.1016/j.ijantimicag.2018.11.011

Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?

Dimopoulos, George, Koulenti, Despoina, Parker, Suzanne L, Roberts, Jason A, Arvaniti, Kostoula and Poulakou, Garyphalia (2019). Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?. Expert Review of Anti-infective Therapy, 17 (3) 14787210.2019.1573669, 201-210. doi: 10.1080/14787210.2019.1573669

A robust statistical approach to analyse population pharmacokinetic data in critically ill patients receiving renal replacement therapy

Paul, Sanjoy Ketan, Roberts, Jason A., Lipman, Jeffrey, Deans, Renae and Samanta, Mayukh (2019). A robust statistical approach to analyse population pharmacokinetic data in critically ill patients receiving renal replacement therapy. Clinical Pharmacokinetics, 58 (2), 263-270. doi: 10.1007/s40262-018-0690-1

Antimicrobial dosing in critical care: a pragmatic adult dosing nomogram

Williams, Paul, Beall, Gareth, Cotta, Menino Osbert and Roberts, Jason A. (2019). Antimicrobial dosing in critical care: a pragmatic adult dosing nomogram. International Journal of Antimicrobial Agents, 55 (2) 105837, 105837. doi: 10.1016/j.ijantimicag.2019.10.018

Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients

Cheng, Vesa, Abdul-Aziz, Mohd H., Roberts, Jason A. and Shekar, Kiran (2019). Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients. Expert Opinion on Drug Metabolism & Toxicology, 15 (2), 103-112. doi: 10.1080/17425255.2019.1563596

Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis

Abraham, Jacob, Sinnollareddy, Mahipal G., Roberts, Michael S., Williams, Patricia, Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2019). Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 53 (2), 137-142. doi: 10.1016/j.ijantimicag.2018.09.021

Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models

Dhaese, Sofie A. M., Farkas, Andras, Colin, Pieter, Lipman, Jeffrey, Stove, Veronique, Verstraete, Alain G., Roberts, Jason A. and De Waele, Jan J. (2019). Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models. Journal of Antimicrobial Chemotherapy, 74 (2), 432-441. doi: 10.1093/jac/dky434

Solid nanoparticles for oral antimicrobial drug delivery: a review

Raza, Aun, Sime, Fekade Bruck, Cabot, Peter J., Maqbool, Faheem, Roberts, Jason A. and Falconer, James Robert (2019). Solid nanoparticles for oral antimicrobial drug delivery: a review. Drug Discovery Today, 24 (3), 858-866. doi: 10.1016/j.drudis.2019.01.004

Diagnostic and medical needs for therapeutic drug monitoring of antibiotics

Mabilat, Claude, Gros, Marie Francoise, Nicolau, David, Mouton, Johan W., Textoris, Julien, Roberts, Jason A., Cotta, Menino O., van Belkum, Alex and Caniaux, Isabelle (2019). Diagnostic and medical needs for therapeutic drug monitoring of antibiotics. European Journal of Clinical Microbiology and Infectious Diseases, 39 (5), 791-797. doi: 10.1007/s10096-019-03769-8

Pharmacokinetics/Pharmacodynamics of β-Lactams and therapeutic drug monitoring: from theory to practical issues in the intensive care unit

Williams, Paul, Cotta, Menino Osbert and Roberts, Jason A. (2019). Pharmacokinetics/Pharmacodynamics of β-Lactams and therapeutic drug monitoring: from theory to practical issues in the intensive care unit. Seminars in Respiratory and Critical Care Medicine, 40 (4), 476-487. doi: 10.1055/s-0039-1693498

Therapeutic drug monitoring-guided continuous infusion of piperacillin/tazobactam significantly improves pharmacokinetic target attainment in critically ill patients: a retrospective analysis of four years of clinical experience

Richter, Daniel C., Frey, Otto, Röhr, Anka, Roberts, Jason A., Köberer, Andreas, Fuchs, Thomas, Papadimas, Nikolaos, Heinzel-Gutenbrunner, Monika, Brenner, Thorsten, Lichtenstern, Christoph, Weigand, Markus A. and Brinkmann, Alexander (2019). Therapeutic drug monitoring-guided continuous infusion of piperacillin/tazobactam significantly improves pharmacokinetic target attainment in critically ill patients: a retrospective analysis of four years of clinical experience. Infection, 47 (6), 1001-1011. doi: 10.1007/s15010-019-01352-z

Une voie originale pour une voix originale

Lefrant, Jean-Yves, Lorne, Emmanuel, Asehnoune, Karim, Ausset, Silvain, Beaulieu, Pierre, Biais, Matthieu, Brichant, Jean-Francois, Charbit, Beny, Constantin, Jean-Michel, Cuvillon, Philippe, Dadure, Christophe, Dahmani, Souhayl, David, Jean-Stephane, Fuchs-Buder, Thomas, Geeraerts, Thomas, Godier, Anne, Hanouz, Jean-Luc, Joannes-Boyau, Olivier, Kipnis, Eric, Laudenbach, Vincent, Le Guen, Morgan, Legrand, Matthieu, Lescot, Thomas, Marret, Emmanuel, Mongardon, Nicolas, Ouattara, Alexandre, Pierre, Sebastien, Pirracchio, Romain, Roberts, Jason ... Capdevila, Xavier (2019). Une voie originale pour une voix originale. Anesthesie & Reanimation, 5 (1), 1-3. doi: 10.1016/j.anrea.2018.11.001

Cerebrospinal fluid penetration of very high-dose meropenem: a case report

Kerz, Thomas, Von Loewenich, Friederike D., Roberts, Jason, Neulen, Axel and Ringel, Florian (2018). Cerebrospinal fluid penetration of very high-dose meropenem: a case report. Annals of Clinical Microbiology and Antimicrobials, 17 (1) 47, 47. doi: 10.1186/s12941-018-0299-0

French legal approach to clinical research

Toulouse, Elisabeth, Masseguin, Christophe, Lafont, Brigitte, McGurk, Gordon, Harbonn, Anna, Roberts, Jason A., Granier, Sophie, Dupeyron, Arnaud and Bazin, Jean Etienne (2018). French legal approach to clinical research. Anaesthesia Critical Care and Pain Medicine, 37 (6), 607-614. doi: 10.1016/j.accpm.2018.10.013

Understanding the impact of pathophysiological alterations during critical illness on drug pharmacokinetics

Jamal, Janattul-Ain, Roger, Claire and Roberts, Jason A. (2018). Understanding the impact of pathophysiological alterations during critical illness on drug pharmacokinetics. Anaesthesia Critical Care & Pain Medicine, 37 (6), 515-517. doi: 10.1016/j.accpm.2018.10.006

Pharmacokinetics of ceftolozane-tazobactam during prolonged intermittent renal replacement therapy

Rawlins, Matthew, Cheng, Vesa, Raby, Edward, Dyer, John, Regli, Adrian, Ingram, Paul, McWhinney, Brett C., Ungerer, Jacobus P. J. and Roberts, Jason A. (2018). Pharmacokinetics of ceftolozane-tazobactam during prolonged intermittent renal replacement therapy. Chemotherapy, 63 (4), 203-206. doi: 10.1159/000493196

How to optimize antibiotic pharmacokinetic/pharmacodynamics for Gram-negative infections in critically ill patients

Heffernan, Aaron J., Sime, Fekade B., Taccone, Fabio S. and Roberts, Jason A. (2018). How to optimize antibiotic pharmacokinetic/pharmacodynamics for Gram-negative infections in critically ill patients. Current Opinion in Infectious Diseases, 31 (6), 1-565. doi: 10.1097/QCO.0000000000000494

A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminemia receiving continuous venovenous hemodiafiltration

Sime, Fekade B., Stuart, Janine, Butler, Jenie, Starr, Therese, Wallis, Steven C., Pandey, Saurabh, Lipman, Jeffrey and Roberts, Jason A. (2018). A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminemia receiving continuous venovenous hemodiafiltration. International Journal of Antimicrobial Agents, 52 (4), 506-509. doi: 10.1016/j.ijantimicag.2018.07.008

Therapeutic drug monitoring of β-lactam antibiotics in the critically ill: direct measurement of unbound drug concentrations to achieve appropriate drug exposures

Wong, Gloria, Briscoe, Scott, McWhinney, Brett, Ally, Mumtaz, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A (2018). Therapeutic drug monitoring of β-lactam antibiotics in the critically ill: direct measurement of unbound drug concentrations to achieve appropriate drug exposures. Journal of Antimicrobial Chemotherapy, 73 (11), 3087-3094. doi: 10.1093/jac/dky314

Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam

Sime, Fekade B., Pandey, Saurabh, Karamujic, Nermin, Parker, Suzanne, Alexander, Elizabeth, Loutit, Jeffery, Durso, Stephanie, Griffith, David, Lipman, Jeffrey, Wallis, Steven C. and Roberts, Jason A. (2018). Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam. Antimicrobial Agents and Chemotherapy, 62 (10) e01306, AAC.01306-18. doi: 10.1128/AAC.01306-18

Detailed error analysis for a fractional Adams method with graded meshes

Liu, Yanzhi, Roberts, Jason and Yan, Yubin (2018). Detailed error analysis for a fractional Adams method with graded meshes. Numerical Algorithms, 78 (4), 1195-1216. doi: 10.1007/s11075-017-0419-5

Determining the editorial policy of Anaesthesia Critical Care and Pain Medicine (ACCPM)

Lefrant, Jean-Yves, Lorne, Emmanuel, Asehnoune, Karim, Ausset, Sylvain, Beaulieu, Pierre, Biais, Matthieu, Brichant, Jean-Francois, Charbit, Beny, Constantin, Jean-Michel, Cuvillon, Philippe, Dadure, Christophe, Dahmani, Souhayl, David, Jean-Stephane, Fuchs-Buder, Thomas, Geeraerts, Thomas, Godier, Anne, Hanouz, Jean-Luc, Joannes-Boyau, Olivier, Kipnis, Eric, Laudenbach, Vincent, Le Guen, Morgan, Legrand, Matthieu, Lescot, Thomas, Marret, Emmanuel, Mongardon, Nicolas, Ouattara, Alexandre, Pierre, Sebastien, Roberts, Jason, Schneider, Antoine ... Capdevila, Xavier (2018). Determining the editorial policy of Anaesthesia Critical Care and Pain Medicine (ACCPM). Anaesthesia Critical Care & Pain Medicine, 37 (4), 299-301. doi: 10.1016/j.accpm.2018.07.001

A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models

Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F. and Roberts, Jason A. (2018). A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models. Intensive Care Medicine Experimental, 6 (1) 17, 17. doi: 10.1186/s40635-018-0180-7

β-lactam dosage regimens in septic patients with augmented renal clearance

Jacobs, Alexandra, Taccone, Fabio Silvio, Roberts, Jason A., Jacobs, Frédérique, Wolff, Fleur, Cotton, Frederic, Creteur, Jacques, Vincent, Jean-Louis and Hites, Maya (2018). β-lactam dosage regimens in septic patients with augmented renal clearance. Antimicrobial Agents and Chemotherapy, 62 (9) e02534-17, AAC.02534-17. doi: 10.1128/AAC.02534-17

Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions

Dhanani, Jayesh A., Parker, Suzanne L., Lipman, Jeffrey, Wallis, Steven C., Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle and Roberts, Jason A. (2018). Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions. Journal of Pharmaceutical Analysis, 8 (6), 407-412. doi: 10.1016/j.jpha.2018.07.003

A note on finite difference methods for nonlinear fractional differential equations with non-uniform meshes

Liu, Yanzhi, Roberts, Jason and Yan, Yubin (2018). A note on finite difference methods for nonlinear fractional differential equations with non-uniform meshes. International Journal of Computer Mathematics, 95 (6-7), 1151-1169. doi: 10.1080/00207160.2017.1381691

Pharmacodynamic target attainment for cefepime, meropenem and piperacillin/tazobactam using a pharmacokinetic/pharmacodynamic-based dosing calculator in critically ill patients

Heil, Emily L., Nicolau, David P., Farkas, Andras, Roberts, Jason A. and Thom, Kerri A. (2018). Pharmacodynamic target attainment for cefepime, meropenem and piperacillin/tazobactam using a pharmacokinetic/pharmacodynamic-based dosing calculator in critically ill patients. Antimicrobial Agents and Chemotherapy, 62 (9) e01008-18, AAC.01008-18. doi: 10.1128/AAC.01008-18

Optimised dosing of vancomycin in critically ill Indigenous Australian patients with severe sepsis

Tsai, D., Stewart, P. C., Hewagama, S., Krishnaswamy, S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2018). Optimised dosing of vancomycin in critically ill Indigenous Australian patients with severe sepsis. Anaesthesia and Intensive Care, 46 (4), 374-380. doi: 10.1177/0310057X1804600405

The authors reply

Rhodes, Nathaniel J., Liu, Jiajun, Lipman, Jeffrey and Roberts, Jason A. (2018). The authors reply. Critical Care Medicine, 46 (7), e725-e726. doi: 10.1097/CCM.0000000000003164

New paradigm for rapid achievement of appropriate therapy in special populations: coupling antibiotic dose optimisation rapid microbiological methods

Abdul-Aziz, Mohd H., Driver, Elicia, Lipman, Jeffrey and Roberts, Jason A. (2018). New paradigm for rapid achievement of appropriate therapy in special populations: coupling antibiotic dose optimisation rapid microbiological methods. Expert Opinion on Drug Metabolism and Toxicology, 14 (7), 1-16. doi: 10.1080/17425255.2018.1484452

Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation

Dhanani, Jayesh A., Tang, Patrician, Wallis, Steven C., Parker, Suzanne L., Pandey, Preeti, Fraser, John F., Cohen, Jeremy, Barnett, Adrian, Roberts, Jason R. and Chan, Hak-Kim (2018). Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation. Pulmonary Pharmacology and Therapeutics, 50, 93-99. doi: 10.1016/j.pupt.2018.04.006

Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury

Parker, Suzanne L, Saxena, Manoj, Gowardman, John, Lipman, Jeffrey, Myburgh, John and Roberts, Jason A. (2018). Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury. Journal of Critical Care, 47, 15-20. doi: 10.1016/j.jcrc.2018.05.016

Piperacillin population pharmacokinetics in critically ill adults during sustained low-efficiency dialysis

Kanji, Salmaan, Roberts, Jason A., Xie, Jiao, Alobaid, Abdulaziz, Zelenitsky, Sheryl, Hiremath, Swapnil, Zhang, Guijun, Watpool, Irene, Porteous, Rebecca and Patel, Rakesh (2018). Piperacillin population pharmacokinetics in critically ill adults during sustained low-efficiency dialysis. Annals of Pharmacotherapy, 52 (10), 106002801877377-973. doi: 10.1177/1060028018773771

Risk factors for multidrug-resistant Gram-negative infection in burn patients

Vickers, Mark L., Dulhunty, Joel M., Ballard, Emma, Chapman, Paul, Muller, Michael, Roberts, Jason A. and Cotta, Menino O. (2018). Risk factors for multidrug-resistant Gram-negative infection in burn patients. ANZ Journal of Surgery, 88 (5), 480-485. doi: 10.1111/ans.14144

Predictive performance of a gentamicin population pharmacokinetic model in two Western populations of critically ill patients

Bukkems, Laura H., Roger, Claire, Hodiamont, Caspar J., Lefrant, Jean-Yves, Juffermans, Nicole P., Roberts, Jason A. and van Hest, Reinier M. (2018). Predictive performance of a gentamicin population pharmacokinetic model in two Western populations of critically ill patients. International Journal of Antimicrobial Agents, 52 (2), 218-225. doi: 10.1016/j.ijantimicag.2018.04.016

Population pharmacokinetics/pharmacodynamics of micafungin against Candida species in obese, critically ill, and morbidly obese critically ill patients

Maseda, Emilio, Grau, Santiago, Luque, Sonia, Castillo-Mafla, Maria-Pilar, Suárez-de-la-Rica, Alejandro, Montero-Feijoo, Ana, Salgado, Patricia, Gimenez, Maria-Jose, García-Bernedo, Carlos A., Gilsanz, Fernando and Roberts, Jason A. (2018). Population pharmacokinetics/pharmacodynamics of micafungin against Candida species in obese, critically ill, and morbidly obese critically ill patients. Critical Care, 22 (1) 94, 94. doi: 10.1186/s13054-018-2019-8

Delivering precision antimicrobial therapy through closed-loop control systems

Rawson, T. M., O'Hare, D., Herrero, P., Sharma, S., Moore, L. S. P., de Barra, E., Roberts, J. A., Gordon, A. C., Hope, W., Georgiou, P., Cass, A. E. G. and Holmes, A. H. (2018). Delivering precision antimicrobial therapy through closed-loop control systems. Journal of Antimicrobial Chemotherapy, 73 (4), 835-843. doi: 10.1093/jac/dkx458

Pharmacokinetics of intravenous posaconazole in critically ill patients

Sime, Fekade B., Stuart, Janine, Butler, Jenie, Starr, Therese, Wallis, Steven C., Pandey, Saurabh, Lipman, Jeffrey and Roberts, Jason A. (2018). Pharmacokinetics of intravenous posaconazole in critically ill patients. Antimicrobial Agents and Chemotherapy, 62 (6) e00242-18, e00242-18. doi: 10.1128/AAC.00242-18

Individualising therapy to minimize bacterial multidrug resistance

Heffernan, A. J., Sime, F. B., Lipman, J. and Roberts, J. A. (2018). Individualising therapy to minimize bacterial multidrug resistance. Drugs, 78 (6), 621-641. doi: 10.1007/s40265-018-0891-9

Valganciclovir pharmacokinetics in patients receiving oral prophylaxis following kidney transplantation and model-based predictions of optimal dosing regimens

Tängdén, Thomas, Cojutti, Pier Giorgio, Roberts, Jason A. and Pea, Federico (2018). Valganciclovir pharmacokinetics in patients receiving oral prophylaxis following kidney transplantation and model-based predictions of optimal dosing regimens. Clinical Pharmacokinetics, 57 (11), 1-7. doi: 10.1007/s40262-018-0638-5

Population pharmacokinetics of vancomycin in critically ill patients receiving prolonged intermittent renal replacement therapy

Economou, Caleb J. P., Kielstein, Jan T., Czock, David, Xie, Jiao, Field, Jonathan, Richards, Brent, Tallot, Mandy, Visser, Adam, Koenig, Christina, Hafer, Carsten, Schmidt, Julius J., Lipman, Jeffrey and Roberts, Jason A. (2018). Population pharmacokinetics of vancomycin in critically ill patients receiving prolonged intermittent renal replacement therapy. International Journal of Antimicrobial Agents, 52 (2), 151-157. doi: 10.1016/j.ijantimicag.2018.03.001

Optimising drug dosing in patients receiving extracorporeal membrane oxygenation

Cheng, Vesa, Abdul-Aziz, Mohd-Hafiz, Roberts, Jason A. and Shekar, Kiran (2018). Optimising drug dosing in patients receiving extracorporeal membrane oxygenation. Journal of Thoracic Disease, 10 (Suppl 5), S629-S641. doi: 10.21037/jtd.2017.09.154

Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2018). Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. The Journal of Antimicrobial Chemotherapy, 73 (6), 1647-1650. doi: 10.1093/jac/dky057

Optimization and evaluation of piperacillin plus tobramycin combination dosage regimens againstfor patients with altered pharmacokineticsthe hollow-fiber infection model and mechanism-based modeling

Yadav, Rajbharan, Rogers, Kate E., Bergen, Phillip J., Bulitta, Jürgen B., Kirkpatrick, Carl M. J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2018). Optimization and evaluation of piperacillin plus tobramycin combination dosage regimens againstfor patients with altered pharmacokineticsthe hollow-fiber infection model and mechanism-based modeling. Antimicrobial Agents and Chemotherapy, 62 (5) e00078, e00078-18. doi: 10.1128/AAC.00078-18

Evidence of clinical response and stability of Ceftolozane/Tazobactam used to treat a carbapenem-resistant Pseudomonas Aeruginosa lung abscess on an outpatient antimicrobial program

Stewart, A., Roberts, J. A., Wallis, S. C., Allworth, A. M., Legg, A. and McCarthy, K. L. (2018). Evidence of clinical response and stability of Ceftolozane/Tazobactam used to treat a carbapenem-resistant Pseudomonas Aeruginosa lung abscess on an outpatient antimicrobial program. International Journal of Antimicrobial Agents, 51 (6), 941-942. doi: 10.1016/j.ijantimicag.2018.02.008

Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review

Guerra Valero, Yarmarly C., Wallis, Steven C., Lipman, Jeffrey, Stove, Christophe, Roberts, Jason A. and Parker, Suzanne L. (2018). Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review. Bioanalysis, 10 (6), 407-423. doi: 10.4155/bio-2017-0269

Development of a dosing nomogram for continuous-infusion meropenem in critically ill patients based on a validated population pharmacokinetic model

Minichmayr, Iris K., Roberts, Jason A., Frey, Otto R., Roehr, Anka C., Kloft, Charlotte and Brinkmann, Alexander (2018). Development of a dosing nomogram for continuous-infusion meropenem in critically ill patients based on a validated population pharmacokinetic model. The Journal of Antimicrobial Chemotherapy, 73 (5), 1330-1339. doi: 10.1093/jac/dkx526

Beta-Lactam Therapeutic Drug Monitoring in the Critically Ill Children: Big Solution for Infections in Small People?

Roberts, Jason A. (2018). Beta-Lactam Therapeutic Drug Monitoring in the Critically Ill Children: Big Solution for Infections in Small People?. Critical Care Medicine, 46 (2), 335-337. doi: 10.1097/CCM.0000000000002862

Impact of Quality Bundle Enforcement by a Critical Care Pharmacist on Patient Outcome and Costs

Leguelinel-Blache, Géraldine, Nguyen, Tri-Long, Louart, Benjamin, Poujol, Hélène, Lavigne, Jean-Philippe, Roberts, Jason A, Muller, Laurent, Kinowski, Jean-Marie, Roger, Claire and Lefrant, Jean-Yves (2018). Impact of Quality Bundle Enforcement by a Critical Care Pharmacist on Patient Outcome and Costs. Critical Care Medicine, 46 (2), 199-207. doi: 10.1097/CCM.0000000000002827

Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis

Rhodes, Nathaniel J., Liu, Jiajun, O'Donnell, J. Nicholas, Dulhunty, Joel M., Abdul-Aziz, Mohd H., Berko, Patsy Y., Nadler, Barbara, Lipman, Jeffery and Roberts, Jason A. (2018). Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis. Critical Care Medicine, 46 (2), 236-243. doi: 10.1097/CCM.0000000000002836

A UHPLC–MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent

Naicker, Saiyuri, Guerra Valero, Yarmarly C., Ordenez Meija, Jenny L., Lipman, Jeffrey, Roberts, Jason A., Wallis, Steven C. and Parker, Suzanne L. (2018). A UHPLC–MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent. Journal of Pharmaceutical and Biomedical Analysis, 148, 324-333. doi: 10.1016/j.jpba.2017.10.023

Pharmacokinetics of meropenem in septic patients on sustained low-efficiency dialysis: a population pharmacokinetic study

Braune, Stephan, König, Christina, Roberts, Jason A., Nierhaus, Axel, Steinmetz, Oliver, Baehr, Michael, Kluge, Stefan and Langebrake, Claudia (2018). Pharmacokinetics of meropenem in septic patients on sustained low-efficiency dialysis: a population pharmacokinetic study. Critical Care (London, England), 22 (1) 25, 1-10. doi: 10.1186/s13054-018-1940-1

Re: 'Is a randomized trial of a short course of aminoglycoside added to β-lactam antibiotics for empirical treatment in critically ill patients with sepsis justified?' Pharmacokinetic/pharmacodynamic considerations

Heffernan, A., Lipman, J. and Roberts, J. (2018). Re: 'Is a randomized trial of a short course of aminoglycoside added to β-lactam antibiotics for empirical treatment in critically ill patients with sepsis justified?' Pharmacokinetic/pharmacodynamic considerations. Clinical Microbiology and Infection, 24 (6), 666-667. doi: 10.1016/j.cmi.2017.12.019

Differences in suppression of regrowth and resistance despite similar initial bacterial killing for meropenem and piperacillin/tazobactam against Pseudomonas aeruginosa and Escherichia coli

Bergen, Phillip J., Bulitta, Jürgen B., Sime, Fekade B., Lipman, Jeffrey, McGregor, Megan J., Millen, Nada, Paterson, David L., Kirkpatrick, Carl M. J., Roberts, Jason A. and Landersdorfer, Cornelia B. (2018). Differences in suppression of regrowth and resistance despite similar initial bacterial killing for meropenem and piperacillin/tazobactam against Pseudomonas aeruginosa and Escherichia coli. Diagnostic Microbiology and Infectious Disease, 91 (1), 69-76. doi: 10.1016/j.diagmicrobio.2017.12.019

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

Blaskovich, Mark A T, Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G, Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E, Sidjabat, Hanna E, Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R, Beevers, Andrew P G, Smith, Richard A G ... Cooper, Matthew A. (2018). Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature Communications, 9 (1) 02123, 22. doi: 10.1038/s41467-017-02123-w

In vitro removal of anti-infective agents by a novel cytokine adsorbent system

König, Christina, Röhr, Anka C., Frey, Otto R., Brinkmann, Alexander, Roberts, Jason A., Wichmann, Dominic, Braune, Stephan, Kluge, Stefan and Nierhaus, Axel (2018). In vitro removal of anti-infective agents by a novel cytokine adsorbent system. International Journal of Artificial Organs, 42 (2), 57-64. doi: 10.1177/0391398818812601

Prevalence of augmented renal clearance and performance of glomerular filtration estimates in Indigenous Australian patients requiring intensive care admission

Tsai, D., Udy, A. A., Stewart, P. C., Gourley, S., Morick, N. M., Lipman, J. and Roberts, J. A. (2018). Prevalence of augmented renal clearance and performance of glomerular filtration estimates in Indigenous Australian patients requiring intensive care admission. Anaesthesia and Intensive Care, 46 (1), 42-50. doi: 10.1177/0310057X1804600107

Antimicrobial resistance and antibiotic stewardship programs in the ICU: insistence and persistence in the fight against resistance. a position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance

De Waele, Jan J., Akova, Murat, Antonelli, Massimo, Canton, Rafael, Carlet, Jean, De Backer, Daniel, Dimopoulos, George, Garnacho-Montero, José, Kesecioglu, Jozef, Lipman, Jeffrey, Mer, Mervyn, Paiva, José-Artur, Poljak, Mario, Roberts, Jason A., Rodriguez Bano, Jesus, Timsit, Jean-François, Zahar, Jean-Ralph and Bassetti, Matteo (2017). Antimicrobial resistance and antibiotic stewardship programs in the ICU: insistence and persistence in the fight against resistance. a position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance. Intensive Care Medicine, 44 (2), 189-196. doi: 10.1007/s00134-017-5036-1

Population pharmacokinetics of piperacillin continuous infusion in critically ill patients

Dhaese, Sofie A. M., Roberts, Jason A., Carlier, Mieke, Verstraete, Alain G., Stove, Veronique and De Waele, Jan J. (2017). Population pharmacokinetics of piperacillin continuous infusion in critically ill patients. International Journal of Antimicrobial Agents, 51 (4), 594-600. doi: 10.1016/j.ijantimicag.2017.12.015

Population pharmacokinetics of total and unbound teicoplanin concentrations and dosing simulations in patients with haematological malignancy

Byrne, Catherine J., Parton, Ted, McWhinney, Brett, Fennell, Jerome P., O'Byrne, Philomena, Deasy, Evelyn, Egan, Sean, Enright, Helen, Desmond, Ronan, Ryder, Sheila A., D'Arcy, Deirdre M., McHugh, Johnny and Roberts, Jason A. (2017). Population pharmacokinetics of total and unbound teicoplanin concentrations and dosing simulations in patients with haematological malignancy. The Journal of Antimicrobial Chemotherapy, 73 (4), 995-1003. doi: 10.1093/jac/dkx473

Fosfomycin efficacy and emergence of resistance among Enterobacteriaceae in an in vitro dynamic bladder infection model

Abbott, Iain J., Meletiadis, Joseph, Belghanch, Imane, Wijma, Rixt A., Kanioura, Lamprini, Roberts, Jason A., Peleg, Anton Y. and Mouton, Johan W. (2017). Fosfomycin efficacy and emergence of resistance among Enterobacteriaceae in an in vitro dynamic bladder infection model. The Journal of Antimicrobial Chemotherapy, 73 (3), 709-719. doi: 10.1093/jac/dkx441

A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples

Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Weiss, Steven, Smith, Camilla, Russell, Lyndal, Smith, Paul, Roberts, Jason A and Wallis, Steven C (2017). A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples. Biomedical Chromatography, 31 (12) e4030, e4030. doi: 10.1002/bmc.4030

Identifying "at-risk" patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections

Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2017). Identifying "at-risk" patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections. Critical Care, 21 (1) 283, 1-3. doi: 10.1186/s13054-017-1871-2

A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway

Global Alliance for Infections in Surgery Working Group and Roberts, Jason (2017). A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway. Surgical Infections, 18 (8), 846-853. doi: 10.1089/sur.2017.219

Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropenia

Sime, Fekade Bruck, Hahn, Uwe, Warner, Morgyn S., Tiong, Ing Soo, Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2017). Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropenia. Antimicrobial Agents and Chemotherapy, 61 (11) e00311-17, e00311-17. doi: 10.1128/AAC.00311-17

Clinical pharmacokinetics and pharmacodynamics of oxazolidinones

Roger, Claire, Roberts, Jason A. and Muller, Laurent (2017). Clinical pharmacokinetics and pharmacodynamics of oxazolidinones. Clinical Pharmacokinetics, 57 (5), 1-17. doi: 10.1007/s40262-017-0601-x

Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation

Sinnah, Fabrice, Shekar, Kiran, Abdul-Aziz, Mohd H, Buscher, Hergen, Diab, Sara D., Fisquet, Stephanie, Fung, Yoke L., McDonald, Charles I., Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan, Xie, Jiao, Fraser, John F., Roberts, Jason A. and ASAP ECMO investigators (2017). Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation. Critical Care and Resuscitation, 19 (Suppl 1), 8-14.

The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use: An appraisal utilizing antibiotics

Udy, Andrew A, Roberts, Jason A, Lipman, Jeffrey and Blot, Stijn (2017). The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use: An appraisal utilizing antibiotics. Advanced drug delivery reviews, 123, 65-74. doi: 10.1016/j.addr.2017.09.019

Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?

Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey and Cotta, Menino Osbert (2017). Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?. Clinical Pharmacokinetics, 57 (4), 439-454. doi: 10.1007/s40262-017-0588-3

Maximally effective dosing regimens of meropenem in patients with septic shock

Sjövall, Fredrik, Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Roberts, Jason A. (2017). Maximally effective dosing regimens of meropenem in patients with septic shock. The Journal of Antimicrobial Chemotherapy, 73 (1) dkx330, 191-198. doi: 10.1093/jac/dkx330

Key considerations on nebulization of antimicrobial agents to mechanically ventilated patients

Rello, J., Rouby, J. J., Sole-Lleonart, C., Chastre, J., Blot, S., Luyt, C. E., Riera, J., Vos, M. C., Monsel, A., Dhanani, J. and Roberts, J. A. (2017). Key considerations on nebulization of antimicrobial agents to mechanically ventilated patients. Clinical Microbiology and Infection, 23 (9), 640-646. doi: 10.1016/j.cmi.2017.03.018

Use of nebulized antimicrobials for the treatment of respiratory infections in invasively mechanically ventilated adults: a position paper from the European Society of Clinical Microbiology and Infectious Diseases

Rello, J., Sole-Lleonart, C., Rouby, J. -J., Chastre, J., Blot, S., Poulakou, G., Luyt, C. -E., Riera, J., Palmer, L. B., Pereira, J. M., Felton, T., Dhanani, J., Bassetti, M., Welte, T. and Roberts, J. A. (2017). Use of nebulized antimicrobials for the treatment of respiratory infections in invasively mechanically ventilated adults: a position paper from the European Society of Clinical Microbiology and Infectious Diseases. Clinical Microbiology and Infection, 23 (9), 629-639. doi: 10.1016/j.cmi.2017.04.011

Erratum: Antimicrobials: A global alliance for optimizing their rational use in intra-abdominal infections (AGORA). [World J Emerg Surg. 11, (2016) (33)] DOI: 10.1186/s13017-016-0089-y

Sartelli, M., Weber, D. G., Ruppé, E., Bassetti, M., Wright, B. J., Ansaloni, L., Catena, F., Coccolini, F., Abu-Zidan, F. M., Coimbra, R., Moore, E. E., Moore, F. A., Maier, R. V., De Waele, J. J., Kirkpatrick, A. W., Griffiths, E. A., Eckmann, C., Brink, A. J., Mazuski, J. E., May, A. K., Sawyer, R. G., Mertz, D., Montravers, P., Kumar, A., Roberts, J. A., Vincent, J. L., Watkins, R. R., Lowman, W., Spellberg, B. ... Viale, P. (2017). Erratum: Antimicrobials: A global alliance for optimizing their rational use in intra-abdominal infections (AGORA). [World J Emerg Surg. 11, (2016) (33)] DOI: 10.1186/s13017-016-0089-y. World Journal of Emergency Surgery, 12 (1) 35, 35. doi: 10.1186/s13017-017-0147-0

Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients

Roger, Claire, Cotta, Menino O., Muller, Laurent, Wallis, Steven C., Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2017). Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients. International Journal of Antimicrobial Agents, 50 (2), 227-231. doi: 10.1016/j.ijantimicag.2017.03.018

Population pharmacokinetics of tigecycline in critically ill patients with severe infections

Xie, Jiao, Roberts, Jason A., Alobaid, Abdulaziz S., Roger, Claire, Wang, Yan, Yang, Qianting, Sun, Jinyao, Dong, Haiyan, Wang, Xue, Xing, Jianfeng, Lipman, Jeffrey and Dong, Yalin (2017). Population pharmacokinetics of tigecycline in critically ill patients with severe infections. Antimicrobial Agents and Chemotherapy, 61 (8) e00345-17, e00345-17. doi: 10.1128/AAC.00345-17

The Global Alliance for Infections in Surgery: Defining a model for antimicrobial stewardship-results from an international cross-sectional survey

Sartelli, Massimo, Labricciosa, Francesco M., Barbadoro, Pamela, Pagani, Leonardo, Ansaloni, Luca, Brink, Adrian J., Carlet, Jean, Khanna, Ashish, Chichom-Mefire, Alain, Coccolini, Federico, Di Saverio, Salomone, May, Addison K. , Viale, Pierluig, Watkins, Richard R., Scudeller, Luigia, Abbo, Lilian M., Abu-Zidan, Fikri M., Adesunkanmi, Abdulrashid K., Al-Dahir, Sara, Al-Hasan, Majdi N., Alis, Halil, Alves, Carlos, Araujo da Silva, Andre .R., Augustin, Goran, Bala, Miklosh, Barie, Philip S., Beltran, Marcelo A., Bhangu, Aneel, Bouchra, Belefquih ... Catena, Fausto (2017). The Global Alliance for Infections in Surgery: Defining a model for antimicrobial stewardship-results from an international cross-sectional survey. World Journal of Emergency Surgery, 12 (1) 34, 34. doi: 10.1186/s13017-017-0145-2

Evolutionary changes in the capsid P2 region of Australian strains of the norovirus GII.Pe_GII.4

Bruggink, Leesa D., Moselen, Jean M., Roberts, Jason A. and Marshall, John A. (2017). Evolutionary changes in the capsid P2 region of Australian strains of the norovirus GII.Pe_GII.4. Journal of Medical Microbiology, 66 (7) 000531, 1014-1022. doi: 10.1099/jmm.0.000531

Australian National Enterovirus Reference Laboratory annual report, 2014

Roberts, Jason, Hobday, Linda, Ibrahim, Aishah, Aitken, Thomas and Thorley, Bruce (2017). Australian National Enterovirus Reference Laboratory annual report, 2014. Communicable Diseases Intelligence Quarterly Report, 41 (2), E161-E180.

An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent

Parker, Suzanne L., Valero, Yarmarly C. Guerra, Mejia, Jenny L. Ordonez, Roger, Claire, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2017). An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent. Bioanalysis, 9 (12), 911-924. doi: 10.4155/bio-2017-0019

Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial

Naik, B. I., Roger, C., Ikeda, K., Todorovic, M. S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2017). Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial. British Journal of Anaesthesia, 118 (6), 876-882. doi: 10.1093/bja/aex026

Pharmacokinetic/pharmacodynamics-optimized antimicrobial therapy in patients with hospital-acquired pneumonia/ventilator-associated pneumonia

Sulaiman, Helmi, Abdul-Aziz, Mohd H. and Roberts, Jason A. (2017). Pharmacokinetic/pharmacodynamics-optimized antimicrobial therapy in patients with hospital-acquired pneumonia/ventilator-associated pneumonia. Seminars in Respiratory and Critical Care Medicine, 38 (3) 01275, 271-286. doi: 10.1055/s-0037-1602716

Variability in trough total and unbound teicoplanin concentrations and achievement of therapeutic drug monitoring targets in adult patients with hematological malignancy

Byrne, Catherine J., Roberts, Jason A., McWhinney, Brett, Fennell, Jerome P., O'Byrne, Philomena, Deasy, Evelyn, Egan, Sean, Desmond, Ronan, Enright, Helen, Ryder, Sheila A., D'Arcy, Deirdre M. and McHugh, Johnny (2017). Variability in trough total and unbound teicoplanin concentrations and achievement of therapeutic drug monitoring targets in adult patients with hematological malignancy. Antimicrobial Agents and Chemotherapy, 61 (6) e02466-16, e02466-16. doi: 10.1128/AAC.02466-16

Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy

Economou, Caleb J. P., Wong, Gloria, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2017). Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy. International Journal of Antimicrobial Agents, 49 (5), 589-594. doi: 10.1016/j.ijantimicag.2017.01.009

Nebulization of antiinfective agents in invasively mechanically ventilated adults: a systematic review and meta-analysis

Sole-Lleonart, Candela, Rouby, Jean-Jacques, Blot, Stijn, Poulakou, Garyfallia, Chastre, Jean, Palmer, Lucy B., Bassetti, Matteo, Luyt, Charles-Edouard, Pereira, Jose M., Riera, Jordi, Felton, Tim, Dhanani, Jayesh, Welte, Tobias, Garcia-Alamino, Jose M., Roberts, Jason A. and Rello, Jordi (2017). Nebulization of antiinfective agents in invasively mechanically ventilated adults: a systematic review and meta-analysis. Anesthesiology, 126 (5), 890-908. doi: 10.1097/ALN.0000000000001570

Population pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysis

Konig, Christina, Braune, Stephan, Roberts, Jason A., Nierhaus, Axel, Steinmetz, Oliver M., Baehr, Michael, Frey, Otto R., Langebrake, Claudia and Kluge, Stefan (2017). Population pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysis. Journal of Antimicrobial Chemotherapy, 72 (5), 1433-1440. doi: 10.1093/jac/dkw592

Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model

Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2017). Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model. Antimicrobial Agents and Chemotherapy, 61 (5) e02642, e02642-16. doi: 10.1128/AAC.02642-16

The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections

Tangden, T., Ramos Martin, V., Felton, T. W., Nielsen, E. I., Marchand, S., Bruggemann, R. J., Bulitta, J. B., Bassetti, M., Theuretzbacher, U., Tsuji, B. T., Wareham, D. W., Friberg, L. E., de Waele, J. J., Tam, V. H. and Roberts, J. A. (2017). The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections. Intensive Care Medicine, 43 (7), 1021-1032. doi: 10.1007/s00134-017-4780-6

What’s new in pharmacokinetics of antimicrobials in AKI and RRT?

Roberts, Jason A., Lefrant, Jean-Yves and Lipman, Jeffrey (2017). What’s new in pharmacokinetics of antimicrobials in AKI and RRT?. Intensive Care Medicine, 43 (6), 1-3. doi: 10.1007/s00134-017-4789-x

The effect of pharmacists on ward rounds measured by the STOPP/START tool in a specialized geriatric unit

Mulvogue, K., Roberts, J. A., Coombes, I., Cottrell, N., Kanagarajah, S. and Smith, A. (2017). The effect of pharmacists on ward rounds measured by the STOPP/START tool in a specialized geriatric unit. Journal of Clinical Pharmacy and Therapeutics, 42 (2), 178-184. doi: 10.1111/jcpt.12489

The use of bloodstream infection mortality to measure the impact of antimicrobial stewardship interventions: assessing the evidence

Coulter, Sonali, Roberts, Jason A., Hajkowicz, Krispin and Halton, Kate (2017). The use of bloodstream infection mortality to measure the impact of antimicrobial stewardship interventions: assessing the evidence. Infectious Disease Reports, 9 (1), 8-12. doi: 10.4081/idr.2017.6849

Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial

Udy, Andrew A., Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K. and Lipman, Jeffrey (2017). Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial. International Journal of Antimicrobial Agents, 49 (5), 624-630. doi: 10.1016/j.ijantimicag.2016.12.022

Population pharmacokinetics of teicoplanin and attainment of pharmacokinetic/pharmacodynamic targets in adult patients with haematological malignancy

Byrne, C. J., Roberts, J. A., McWhinney, B., Ryder, S. A., Fennell, J. P., O'Byrne, P., Deasy, E., Egan, S., Desmond, R., Enright, H., D'Arcy, D. M. and McHugh, J. (2017). Population pharmacokinetics of teicoplanin and attainment of pharmacokinetic/pharmacodynamic targets in adult patients with haematological malignancy. Clinical Microbiology and Infection, 23 (9), 674.e7-674.e13. doi: 10.1016/j.cmi.2017.02.032

Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Roger, Claire, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2017). Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients. Antimicrobial Agents and Chemotherapy, 61 (3) e01276, e01276-16. doi: 10.1128/AAC.01276-16

Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review

Paruk, Fathima, Sime, Fekade B., Lipman, Jeffrey and Roberts, Jason A. (2017). Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review. International Journal of Antimicrobial Agents, 49 (4), 395-402. doi: 10.1016/j.ijantimicag.2016.12.014

Does furosemide increase oxidative stress in acute kidney injury?

Silbert, Benjamin I., Ho, Kwok M., Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2017). Does furosemide increase oxidative stress in acute kidney injury?. Antioxidants & Redox Signaling, 26 (5), 221-226. doi: 10.1089/ars.2016.6845

Right dose, right now: customized drug dosing in the critically ill

Roberts, Jason A., Kumar, Anand and Lipman, Jeffrey (2017). Right dose, right now: customized drug dosing in the critically ill. Critical Care Medicine, 45 (2), 331-336. doi: 10.1097/CCM.0000000000002210

Augmented renal clearance in traumatic brain injury: a single-center observational study of atrial natriuretic peptide, cardiac output, and creatinine clearance

Udy, Andrew A., Jarrett, Paul, Lassig-Smith, Melissa, Stuart, Janine, Starr, Therese, Dunlop, Rachel, Deans, Renae, Roberts, Jason A., Senthuran, Siva, Boots, Robert, Bisht, Kavita, Bulmer, Andrew C. and Lipman, Jeffrey (2017). Augmented renal clearance in traumatic brain injury: a single-center observational study of atrial natriuretic peptide, cardiac output, and creatinine clearance. Journal of Neurotrauma, 34 (1), 137-144. doi: 10.1089/neu.2015.4328

Pharmacodynamics of aerosolized fosfomycin and amikacin against resistant clinical isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a hollow-fiber infection model: experimental basis for combination therapy

Sime, Fekade Bruck, Johnson, Adam, Whalley, Sarah, Santoyo-Castelazo, Anahi, Montgomery, A. Bruce, Walters, Kathie Ann, Lipman, Jeffrey, Hope, William W. and Roberts, Jason A. (2017). Pharmacodynamics of aerosolized fosfomycin and amikacin against resistant clinical isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a hollow-fiber infection model: experimental basis for combination therapy. Antimicrobial Agents and Chemotherapy, 61 (1) e01763-16, e01763-16. doi: 10.1128/AAC.01763-16

Caspofungin Population Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-Venous Haemofiltration or Haemodiafiltration

Roger, C., Wallis, S.C., Muller, L., Saissi, G., Lipman, J., Bruggemann, R.J., Lefrant, J.-Y. and Roberts, J.A. (2016). Caspofungin Population Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-Venous Haemofiltration or Haemodiafiltration. Clinical Pharmacokinetics, 56 (9), 1-12. doi: 10.1007/s40262-016-0495-z

Antibiotic dosing for multidrug-resistant pathogen pneumonia

Abdul-Aziz, Mohd. H., Lipman, Jeffrey and Roberts, Jason A. (2016). Antibiotic dosing for multidrug-resistant pathogen pneumonia. Current Opinion in Infectious Diseases, 30 (2), 231-239. doi: 10.1097/QCO.0000000000000348

Pharmacokinetics of piperacillin in critically ill Australian Indigenous patients with severe sepsis

Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016). Pharmacokinetics of piperacillin in critically ill Australian Indigenous patients with severe sepsis. Antimicrobial Agents and Chemotherapy, 60 (12), 7402-7406. doi: 10.1128/AAC.01657-16

Total and unbound ceftriaxone pharmacokinetics in critically ill Australian Indigenous patients with severe sepsis

Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016). Total and unbound ceftriaxone pharmacokinetics in critically ill Australian Indigenous patients with severe sepsis. International Journal of Antimicrobial Agents, 48 (6), 748-752. doi: 10.1016/j.ijantimicag.2016.09.021

Comparative evaluation of the predictive performances of three different structural population pharmacokinetic models to predict future voriconazole concentrations

Farkas, Andras, Daroczi, Gergely, Villasurda, Phillip, Dolton, Michael, Nakagaki, Midori and Roberts, Jason A. (2016). Comparative evaluation of the predictive performances of three different structural population pharmacokinetic models to predict future voriconazole concentrations. Antimicrobial Agents and Chemotherapy, 60 (11), 6806-6812. doi: 10.1128/AAC.00970-16

Effect of obesity on the population pharmacokinetics of fluconazole in critically Ill patients

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Sinnollareddy, Mahipal G., Roger, Claire, Lipman, Jeffrey and Roberts, Jason A. (2016). Effect of obesity on the population pharmacokinetics of fluconazole in critically Ill patients. Antimicrobial Agents and Chemotherapy, 60 (11), 6550-6557. doi: 10.1128/AAC.01088-16

Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin

Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016). Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin. Bioanalysis, 8 (21), 2235-2242. doi: 10.4155/bio-2016-0159

LC-MS/MS for therapeutic drug monitoring of anti-infective drugs

Veringa, Anette, Sturkenboom, Marieke G. G., Dekkers, Bart G. J., Koster, Remco A., Roberts, Jason A., Peloquin, Charles A., Touw, Daan J. and Alffenaar, Jan-Willem C. (2016). LC-MS/MS for therapeutic drug monitoring of anti-infective drugs. Trends in Analytical Chemistry, 84, 34-40. doi: 10.1016/j.trac.2015.11.026

Optimising meropenem dosing in critically ill Australian Indigenous patients with severe sepsis

Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016). Optimising meropenem dosing in critically ill Australian Indigenous patients with severe sepsis. International Journal of Antimicrobial Agents, 48 (5), 542-546. doi: 10.1016/j.ijantimicag.2016.08.015

Fundamentals of aerosol therapy in critical care

Dhanani, Jayesh, Fraser, John F., Chan, Hak-Kim, Rello, Jordi, Cohen, Jeremy and Roberts, Jason A. (2016). Fundamentals of aerosol therapy in critical care. Critical Care, 20 (1) 269, 269. doi: 10.1186/s13054-016-1448-5

Are new gentamicin dosing guidelines suitable for achieving target concentrations in patients with sepsis and septic shock?

Tabah, Alexis, Lipman, Jeffrey and Roberts, Jason A. (2016). Are new gentamicin dosing guidelines suitable for achieving target concentrations in patients with sepsis and septic shock?. Anaesthesia, Critical Care and Pain Medicine, 35 (5), 311-312. doi: 10.1016/j.accpm.2016.08.002

Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis

Abdul-Aziz, Mohd H., Sulaiman, Helmi, Mat-Nor, Mohd-Basri, Rai, Vineya, Wong, Kang K., Hasan, Mohd S., Abd Rahman, Azrin N., Jamal, Janattul A., Wallis, Steven C., Lipman, Jeffrey, Staatz, Christine E. and Roberts, Jason A. (2016). Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis. Intensive Care Medicine, 42 (10), 1535-1545. doi: 10.1007/s00134-015-4188-0

Comparative population plasma and tissue pharmacokinetics of micafungin in critically ill patients with severe burn injuries and patients with complicated intra-abdominal infection

Garcia-De-Lorenzo, A., Luque, S., Grau, S., Agrifoglio, A., Cachafeiro, L., Herrero, E., Asensio, M. J., Sanchez, S. M. and Roberts, J. A. (2016). Comparative population plasma and tissue pharmacokinetics of micafungin in critically ill patients with severe burn injuries and patients with complicated intra-abdominal infection. Antimicrobial Agents and Chemotherapy, 60 (10), 5914-5921. doi: 10.1128/AAC.00727-16

Determinants of urinary output response to IV furosemide in acute kidney injury: a pharmacokinetic/pharmacodynamic study

Silbert, Benjamin I., Ho, Kwok M., Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2016). Determinants of urinary output response to IV furosemide in acute kidney injury: a pharmacokinetic/pharmacodynamic study. Critical Care Medicine, 44 (10), e923-e929. doi: 10.1097/CCM.0000000000001823

Erratum: is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients? The IPHIVAP investigators of the Australian and New Zealand Intensive Care Society Clinical Trials Group

Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016). Erratum: is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients? The IPHIVAP investigators of the Australian and New Zealand Intensive Care Society Clinical Trials Group. Journal of Critical Care, 35, 230-230. doi: 10.1016/j.jcrc.2016.06.021

Integrated pharmacokinetic-pharmacodynamic modelling to evaluate antimicrobial prophylaxis in abdominal surgery

Zelenitsky, S. A., Lawson, C., Calic, D., Ariano, R. E., Roberts, J. A., Lipman, J. and Zhanel, G. G. (2016). Integrated pharmacokinetic-pharmacodynamic modelling to evaluate antimicrobial prophylaxis in abdominal surgery. Journal of Antimicrobial Chemotherapy, 71 (10) dkw247, 2902-2908. doi: 10.1093/jac/dkw247

Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?

Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016). Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?. Journal of Critical Care, 35, 231-239. doi: 10.1016/j.jcrc.2016.06.022

Prolonged administration of beta-lactam antibiotics - a comprehensive review and critical appraisal

Osthoff, Michael, Siegemund, Martin, Balestra, Gianmarco, Abdul-Aziz, Mohd H. and Roberts, Jason A. (2016). Prolonged administration of beta-lactam antibiotics - a comprehensive review and critical appraisal. Swiss Medical Weekly, 146 (4142), w14368-w14368. doi: 10.4414/smw.2016.14368

Tigecycline use in the outpatient parenteral antibiotic therapy setting

Ingram, P. R., Rawlins, M. D. M., Murray, R. J., Roberts, J. A. and Manning, L. (2016). Tigecycline use in the outpatient parenteral antibiotic therapy setting. European Journal of Clinical Microbiology and Infectious Diseases, 35 (10), 1673-1677. doi: 10.1007/s10096-016-2709-6

Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials

Roberts, Jason A., Abdul-Aziz, Mohd-Hafiz, Davis, Joshua S., Dulhunty, Joel M., Cotta, Menino O., Myburgh, John, Bellomo, Rinaldo and Lipman, Jeffrey (2016). Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials. American Journal of Respiratory and Critical Care Medicine, 194 (6), 681-691. doi: 10.1164/rccm.201601-0024OC

Effect of different renal function on antibacterial effects of piperacillin against Pseudomonas aeruginosa evaluated via the hollow-fibre infection model and mechanism-based modelling

Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2016). Effect of different renal function on antibacterial effects of piperacillin against Pseudomonas aeruginosa evaluated via the hollow-fibre infection model and mechanism-based modelling. Journal of Antimicrobial Chemotherapy, 71 (9), 2509-2520. doi: 10.1093/jac/dkw153

Executive summary: management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the infectious diseases society of America and the American thoracic society

Kalil, Andre C., Metersky, Mark L., Klompas, Michael, Muscedere, John, Sweeney, Daniel A, Palmer, Lucy B., Napolitano, Lena M., O'Grady, Naomi P., Bartlett, John G., Carratala, Jordi, El Solh, Ali A., Ewig, Santiago, Fey, Paul D., File, Thomas M., Restrepo, Marcos I., Roberts, Jason A., Waterer, Grant W., Cruse, Peggy, Knight, Shandra L. and Brozek, Jan L. (2016). Executive summary: management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the infectious diseases society of America and the American thoracic society. Clinical Infectious Diseases, 63 (5), 575-582. doi: 10.1093/cid/ciw504

Is high-dose beta-lactam therapy associated with excessive drug toxicity in critically ill patients?

Mcdonald, Craig, Cotta, Menino O., Little, Peter J., Mcwhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2016). Is high-dose beta-lactam therapy associated with excessive drug toxicity in critically ill patients?. Minerva Anestesiologica, 82 (9), 957-965.

Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the infectious diseases society of America and the American thoracic society

Kalil, Andre C., Metersky, Mark L., Klompas, Michael, Muscedere, John, Sweeney, Daniel A., Palmer, Lucy B., Napolitano, Lena M., O'Grady, Naomi P., Bartlett, John G., Carratala, Jordi, El Solh, Ali A., Ewig, Santiago, Fey, Paul D., File, Thomas M., Jr., Restrepo, Marcos I., Roberts, Jason A., Waterer, Grant W., Cruse, Peggy, Knight, Shandra L. and Brozek, Jan L. (2016). Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the infectious diseases society of America and the American thoracic society. Clinical Infectious Diseases, 63 (5), E61-E111. doi: 10.1093/cid/ciw353

Uncertainty in antibiotic dosing in critically ill neonate and pediatric patients: can microsampling provide the answers?

Dorofaeff, Tavey, Bandini, Rossella M., Lipman, Jeffrey, Ballot, Daynia E., Roberts, Jason A. and Parker, Suzanne L. (2016). Uncertainty in antibiotic dosing in critically ill neonate and pediatric patients: can microsampling provide the answers?. Clinical Therapeutics, 38 (9), 1961-1975. doi: 10.1016/j.clinthera.2016.07.093

Antibiotic dosing in obesity: a BIG challenge

Hanrahan, Timothy P., Lipman, Jeffrey and Roberts, Jason A. (2016). Antibiotic dosing in obesity: a BIG challenge. Critical Care, 20 (240) 240, 240. doi: 10.1186/s13054-016-1426-y

Effect of obesity on the population pharmacokinetics of meropenem in critically ill patients

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Ordonez Mejia, Jenny Lisette, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). Effect of obesity on the population pharmacokinetics of meropenem in critically ill patients. Antimicrobial Agents and Chemotherapy, 60 (8), 4577-4584. doi: 10.1128/AAC.00531-16

Influence of renal replacement modalities on amikacin population pharmacokinetics in critically ill patients on continuous renal replacement therapy

Roger, Claire, Wallis, Steven C., Muller, Laurent, Saissi, Gilbert, Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2016). Influence of renal replacement modalities on amikacin population pharmacokinetics in critically ill patients on continuous renal replacement therapy. Antimicrobial Agents and Chemotherapy, 60 (8), 4901-4909. doi: 10.1128/AAC.00828-16

Intratracheal administration of antimicrobial agents in mechanically ventilated adults: an international survey on delivery practices and safety

Sole-Lleonart, Candela, Rouby, Jean-Jacques, Chastre, Jean, Poulakou, Garyfallia, Palmer, Lucy B., Blot, Stijn, Felton, Tim, Bassetti, Matteo, Luyt, Charles-Eduard, Pereira, Joao Manuel, Riera, Jordi, Welte, Tobias, Roberts, Jason A. and Rello, Jordi (2016). Intratracheal administration of antimicrobial agents in mechanically ventilated adults: an international survey on delivery practices and safety. Respiratory Care, 61 (8), 1008-1014. doi: 10.4187/respcare.04519

Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?. The IPHIVAP investigators of the Australian and New Zealand Intensive Care Society Clinical Trials Group

Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016). Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?. The IPHIVAP investigators of the Australian and New Zealand Intensive Care Society Clinical Trials Group. Journal of Critical Care, 34, 95-102. doi: 10.1016/j.jcrc.2016.04.005

New regimen for continuous infusion of vancomycin in critically ill patients

Cristallini, Stefano, Hites, Maya, Kabtouri, Hakim, Roberts, Jason A., Beumier, Marjorie, Cotton, Frederic, Lipman, Jeffrey, Jacobs, Frederique, Vincent, Jean-Louis, Creteur, Jacques and Taccone, Fabio Silvio (2016). New regimen for continuous infusion of vancomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 60 (8), 4750-4756. doi: 10.1128/AAC.00330-16

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Sartelli, Massimo, Weber, Dieter G., Ruppe, Etienne, Bassetti, Matteo, Wright, Brian J., Ansaloni, Luca, Catena, Fausto, Coccolini, Federico, Abu-Zidan, Fikri M., Coimbra, Raul, Moore, Ernest E., Moore, Frederick A., Maier, Ronald V., De Waele, Jan J., Kirkpatrick, Andrew W., Griffiths, Ewen A., Eckmann, Christian, Brink, Adrian J., Mazuski, John E., May, Addison K., Sawyer, Rob G., Mertz, Dominik, Montravers, Philippe, Kumar, Anand, Roberts, Jason A., Vincent, Jean-Louis, Watkins, Richard R., Lowman, Warren, Spellberg, Brad ... Viale, Perluigi (2016). Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA). World Journal of Emergency Surgery, 11 (1) 35, 33. doi: 10.1186/s13017-016-0089-y

Pharmacokinetics of intraperitoneal cefalothin and cefazolin in patients being treated for peritoneal dialysis-associated peritonitis

Roberts, Darren M., Ranganathan, Dwarakanathan, Wallis, Steven C., Varghese, Julie M., Kark, Adrian, Lipman, Jeffrey and Roberts, Jason A. (2016). Pharmacokinetics of intraperitoneal cefalothin and cefazolin in patients being treated for peritoneal dialysis-associated peritonitis. Peritoneal Dialysis International, 36 (4), 415-420. doi: 10.3747/pdi.2015.00008

Stability of antibiotics for intraperitoneal administration in extraneal 7.5% icodextrin peritoneal dialysis bags (stab study)

Ranganathan, Dwarakanathan, Naicker, Saiyuri, Wallis, Steven C., Lipman, Jeffrey, Ratanjee, Sharad K. and Roberts, Jason A. (2016). Stability of antibiotics for intraperitoneal administration in extraneal 7.5% icodextrin peritoneal dialysis bags (stab study). Peritoneal Dialysis International, 36 (4), 421-426. doi: 10.3747/pdi.2015.00062

Comparison of equal doses of continuous venovenous haemofiltration and haemodiafiltration on ciprofloxacin population pharmacokinetics in critically ill patients

Roger, Claire, Wallis, Steven C., Louart, Benjamin, Lefrant, Jean-Yves, Lipman, Jeffrey, Muller, Laurent and Roberts, Jason A. (2016). Comparison of equal doses of continuous venovenous haemofiltration and haemodiafiltration on ciprofloxacin population pharmacokinetics in critically ill patients. Journal of Antimicrobial Chemotherapy, 71 (6), 1643-1650. doi: 10.1093/jac/dkw043

Determination of cefalothin and cefazolin in human plasma, urine and peritoneal dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans

Parker, Suzanne L., Guerra Valero, Yarmarly C., Roberts, Darren M., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016). Determination of cefalothin and cefazolin in human plasma, urine and peritoneal dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Biomedical Chromatography, 30 (6), 872-879. doi: 10.1002/bmc.3622

Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists

Cotta, Menino O., Dulhunty, Joel M., Roberts, Jason A., Myburgh, John and Lipman, Jeffrey (2016). Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists. International Journal of Antimicrobial Agents, 47 (6), 436-438. doi: 10.1016/j.ijantimicag.2016.02.017

We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?

Cotta, Menino Osbert, Roberts, Jason A. and Lipman, Jeffrey (2016). We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?. Critical Care, 20 (1) 163. doi: 10.1186/s13054-016-1348-8

Diagnosis and management of invasive candidiasis in the ICU: an updated approach to an old enemy

Calandra, Thierry, Roberts, Jason A., Antonelli, Massimo, Bassetti, Matteo and Vincent, Jean-Louis (2016). Diagnosis and management of invasive candidiasis in the ICU: an updated approach to an old enemy. Critical Care, 20 (1) 125, 125. doi: 10.1186/s13054-016-1313-6

Advances in antibiotic therapy in the critically ill

Vincent, Jean-Louis, Bassetti, Matteo, Francois, Bruno, Karam, George, Chastre, Jean, Torres, Antoni, Roberts, Jason A., Taccone, Fabio S., Rello, Jordi, Calandra, Thierry, De Backer, Daniel, Welte, Tobias and Antonelli, Massimo (2016). Advances in antibiotic therapy in the critically ill. Critical Care, 20 (1) 133, 133. doi: 10.1186/s13054-016-1285-6

Is there a role for microsampling in antibiotic pharmacokinetic studies?

Parker, Suzanne L., Dorofaeff, Tavey, Lipman, Jeffrey, Ballot, Daynia E., Bandini, Rossella M., Wallis, Steven C. and Roberts, Jason A. (2016). Is there a role for microsampling in antibiotic pharmacokinetic studies?. Expert Opinion on Drug Metabolism and Toxicology, 12 (6), 601-614. doi: 10.1080/17425255.2016.1178238

A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the Intensive Care Unit

Tabah, Alexis, Cotta, Menino Osbert, Garnacho-Montero, Jose, Schouten, Jeroen, Roberts, Jason A., Lipman, Jeffrey, Tacey, Mark, Timsit, Jean-Francois, Leone, Marc, Zahar, Jean Ralph and De Waele, Jan J. (2016). A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the Intensive Care Unit. Clinical Infectious Diseases, 62 (8), 1009-1017. doi: 10.1093/cid/civ1199

Therapeutic drug monitoring of anti-infective agents in critically ill patients

Jager, Nynke G., van Hest, Reinier M., Lipman, Jeffrey, Taccone, Fabio S. and Roberts, Jason A. (2016). Therapeutic drug monitoring of anti-infective agents in critically ill patients. Expert Review of Clinical Pharmacology, 9 (7), 961-979. doi: 10.1586/17512433.2016.1172209

The use and risks of antibiotics in critically ill patients

Denny, Kerina J., Cotta, Menino O., Parker, Suzanne L., Roberts, Jason A. and Lipman, Jeffrey (2016). The use and risks of antibiotics in critically ill patients. Expert Opinion on Drug Safety, 15 (5), 667-678. doi: 10.1517/14740338.2016.1164690

Effect of obesity on the pharmacokinetics of antimicrobials in critically ill patients: a structured review

Alobaid, Abdulaziz S., Hites, Maya, Lipman, Jeffrey, Taccone, Fabio Silvio and Roberts, Jason A. (2016). Effect of obesity on the pharmacokinetics of antimicrobials in critically ill patients: a structured review. International Journal of Antimicrobial Agents, 47 (4), 259-268. doi: 10.1016/j.ijantimicag.2016.01.009

Global survey on nebulization of antimicrobial agents in mechanically ventilated patients: a call for international guidelines

Sole-Lleonart, C., Roberts, J. A., Chastre, J., Poulakou, G., Palmer, L. B., Blot, S., Felton, T., Bassetti, M., Luyt, C.-E., Pereira, J. M., Riera, J., Welte, T., Qiu, H., Rouby, J.-J. and Rello, J. (2016). Global survey on nebulization of antimicrobial agents in mechanically ventilated patients: a call for international guidelines. Clinical Microbiology and Infection, 22 (4), 359-364. doi: 10.1016/j.cmi.2015.12.016

Does critical illness change levofloxacin pharmacokinetics?

Roberts, Jason A., Cotta, Menino Osbert, Cojutti, Piergiorgio, Lugano, Manuela, Rocca, Giorgio D. and Pea, Federico (2016). Does critical illness change levofloxacin pharmacokinetics?. Antimicrobial Agents and Chemotherapy, 60 (3), 1459-1463. doi: 10.1128/AAC.02610-15

Pharmacokinetics of a novel dosing regimen of oral melatonin in critically ill patients

Bellapart, Judith, Roberts, Jason Alexander, Appadurai, Vinesh, Wallis, Steven C., Nunez-Nunez, Maria and Boots, Robert James (2016). Pharmacokinetics of a novel dosing regimen of oral melatonin in critically ill patients. Clinical Chemistry and Laboratory Medicine, 54 (3), 467-472. doi: 10.1515/cclm-2015-0323

SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients

Roberts, Jason A., Choi, Gordon Y. S., Joynt, Gavin M., Paul, Sanjoy K., Deans, Renae, Peake, Sandra, Cole, Louise, Stephens, Dianne, Bellomo, Rinaldo, Turnidge, John, Wallis, Steven C., Roberts, Michael S., Roberts, Darren M., Lassig-Smith, Melissa, Starr, Therese and Lipman, Jeffrey (2016). SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients. Bmc Infectious Diseases, 16 (1) 103, 103.1-103.8. doi: 10.1186/s12879-016-1421-6

What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?

Alobaid, Abdulaziz S., Brinkmann, Alexander, Frey, Otto R., Roehr, Anka C., Luque, Sonia, Grau, Santiago, Wong, Gloria, Abdul-Aziz, Mohd-Hafiz, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?. Journal of Antimicrobial Chemotherapy, 71 (3) dkv412, 696-702. doi: 10.1093/jac/dkv412

Impact of the MIC of piperacillin/tazobactam on the outcome for patients with bacteraemia due to Enterobacteriaceae: the Bacteraemia-MIC project

Delgado-Valverde, Mercedes, Torres, Eva, Valiente-Mendez, Adoracion, Almirante, Benito, Gomez-Zorrilla, Silvia, Borrell, Nuria, Corzo, Juan E., Gurgui, Mercedes, Almela, Manuel, Garcia-Alvarez, Lara, Fontecoba-Sanchez, Maria Crus, Martinez-Martinez, Luis, Canton, Rafael, Praena, Julia, Causse, Manuel, Gutierrez-Gutierrez, Belen, Roberts, Jason A., Farkas, Andras, Pascual, Alvaro, Rodriguez-Bano, Jesus, de Cueto, Marina, Planes Reig, Ana Maria, Quintano, Fe Tubau, Pena, Carmen, Galan Otalora, M. Elvira, Alegria, Carlos Ruiz de, Morosini, M. Isabel, Lepe, Jose Antonio, Cisneros, Jose Miguel ... Abdul-Aziz, Mohd-Hafiz (2016). Impact of the MIC of piperacillin/tazobactam on the outcome for patients with bacteraemia due to Enterobacteriaceae: the Bacteraemia-MIC project. Journal of Antimicrobial Chemotherapy, 71 (2) dkv362, 521-530. doi: 10.1093/jac/dkv362

In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Lassig-Smith, Melissa, Starr, Therese, Robertson, Thomas, Peake, Sandra L. and Roberts, Jason A. (2016). In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis. Antimicrobial Agents and Chemotherapy, 60 (2), 827-832. doi: 10.1128/AAC.02461-15

Population pharmacokinetics of linezolid in critically ill patients on renal replacement therapy: comparison of equal doses in continuous venovenous haemofiltration and continuous venovenous haemodiafiltration

Roger, C., Muller, L., Wallis, S. C., Louart, B., Saissi, G., Lipman, J., Lefrant, J. Y. and Roberts, J. A. (2016). Population pharmacokinetics of linezolid in critically ill patients on renal replacement therapy: comparison of equal doses in continuous venovenous haemofiltration and continuous venovenous haemodiafiltration. Journal of Antimicrobial Chemotherapy, 71 (2) dkv349, 464-470. doi: 10.1093/jac/dkv349

The new Sfar journals are in place

Plaud, Benoît, Lefrant, Jean-Yves, Asehnoune, Karim, Beaulieu, Pierre, Beloeil, Hélène, Brichant, Jean-François, Charbit, Beny, Constantin, Jean-Michel, Cuvillon, Philippe, Dahmani, Souhayl, Fuchs-Buder, Thomas, Geeraerts, Thomas, Godier, Anne, Kern, Christian, Hanouz, Jean-Luc, Laudenbach, Vincent, Lebuffe, Gilles, Le Guen, Morgan, Legrand, Matthieu, Leone, Marc, Lorne, Emmanuel, Marret, Emmanuel, Mongardon, Nicolas, Ouattara, Alexandre, Pierre, Sébastien, Pirracchio, Romain, Roberts, Jason A. and Tourtier, Jean-Pierre (2016). The new Sfar journals are in place. Anaesthesia Critical Care and Pain Medicine, 35 (1), 1-2. doi: 10.1016/j.accpm.2016.01.001

Antibiotic dosing in critically ill patients receiving renal replacement therapy

Sime, Fekade Bruck and Roberts, Jason A. (2016). Antibiotic dosing in critically ill patients receiving renal replacement therapy. Expert Review of Clinical Pharmacology, 9 (4), 497-499. doi: 10.1586/17512433.2016.1133290

Impact of 30 mg/kg amikacin and 8 mg/kg gentamicin on serum concentrations in critically ill patients with severe sepsis

Roger, Claire, Nucci, Bastian, Louart, Benjamin, Friggeri, Arnaud, Knani, Haroun, Evrard, Alexandre, Lavigne, Jean-Philippe, Allaouchiche, Bernard, Lefrant, Jean-Yves, Roberts, Jason A. and Muller, Laurent (2016). Impact of 30 mg/kg amikacin and 8 mg/kg gentamicin on serum concentrations in critically ill patients with severe sepsis. Journal of Antimicrobial Chemotherapy, 71 (1), 208-212. doi: 10.1093/jac/dkv291

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Dulhunty, Joel, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Roberts, Jason A., Paul, Sanjoy, Ribas, Antonio Margarit, De Crop, Luc, Spapen, Herbert, Wauters, Joost, Dugernier, Thierry, Jorens, Philippe, Dapper, Ilse, De Backer, Daniel, Taccone, Fabio S., Ruano, Laura, Afonso, Elsa, Alvarez-Lerma, Francisco ... Ozveren, Arife (2016). Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort. Journal of Antimicrobial Chemotherapy, 71 (1), 196-207. doi: 10.1093/jac/dkv288

Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit

Abdul-Aziz, Mohd H., Abd Rahman, Azrin N., Mat-Nor, Mohd-Basri, Sulaiman, Helmi, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Staatz, Christine E. (2016). Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit. Antimicrobial Agents and Chemotherapy, 60 (1), 206-214. doi: 10.1128/AAC.01543-15

The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial

Saxena, Manoj K., Taylor, Colman, Billot, Laurent, Bompoint, Severine, Gowardman, John, Roberts, Jason A., Lipman, Jeffery and Myburgh, John (2015). The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial. PloS One, 10 (12) e0144740, e0144740. doi: 10.1371/journal.pone.0144740

Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models

Shekar, Kiran, Roberts, Jason A., Barnett, Adrian G., Diab, Sara, Wallis, Steven C., Fung, Yoke L. and Fraser, John F. (2015). Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models. Critical Care, 19 (1) 437, 1-11. doi: 10.1186/s13054-015-1151-y

A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis

Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A.R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K., Lipman, Jeffrey, Bellomo, Rinaldo, Peck, Leah, Young, Helen, Boschert , Catherine, Fletcher, Jason, Smith, Julie, Nand, Kiran, Sara, Treena, Harney, Amy, Rodgers, Helen, Van Haren, Frank, Clarke, Sally, Durham, David, Hannan, Catherine, Matheson, Elisha, Schwartz, Kate ... Paul, Sanjoy (2015). A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis. American Journal of Respiratory and Critical Care Medicine, 192 (11), 1298-1305. doi: 10.1164/rccm.201505-0857OC

Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos

Cotta, M. O., Roberts, J. A. and Lipman, J. (2015). Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos. Medicina Intensiva (English Edition), 39 (9), 563-572. doi: 10.1016/j.medine.2015.07.001

Therapeutic drug monitoring of the beta-lactam antibiotics: what is the evidence and which patients should we be using it for?

Huttner, Angela, Harbarth, Stephan, Hope, William W., Lipman, Jeffrey and Roberts, Jason A. (2015). Therapeutic drug monitoring of the beta-lactam antibiotics: what is the evidence and which patients should we be using it for?. Journal of Antimicrobial Chemotherapy, 70 (12), 3178-3183. doi: 10.1093/jac/dkv201

The efficacy and safety of adrenergic blockade post burn injury: a systematic review and meta-analysis

Flores, Orlando, Stockton, Kellie, Roberts, Jason A., Muller, Michael J. and Paratz, Jennifer D. (2015). The efficacy and safety of adrenergic blockade post burn injury: a systematic review and meta-analysis. Journal of Trauma and Acute Care Surgery, 80 (1), 146-155. doi: 10.1097/TA.0000000000000887

A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans

Parker, Suzanne L., Lipman, Jeffrey, Dimopoulos, George, Roberts, Jason A. and Wallis, Steven C. (2015). A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 115, 509-514. doi: 10.1016/j.jpba.2015.07.013

Augmented renal clearance in critically ill patients: etiology, definition and implications for beta-lactam dose optimization

Sime, Fekade B., Udy, Andrew A. and Roberts, Jason A. (2015). Augmented renal clearance in critically ill patients: etiology, definition and implications for beta-lactam dose optimization. Current Opinion in Pharmacology, 24, 1-6. doi: 10.1016/j.coph.2015.06.002

Early detection of preterm intraventricular hemorrhage from clinical electroencephalography

Iyer, Kartik K., Roberts, James A., Hellstrom-Westas, Lena, Wikstrom, Sverre, Hansen Pupp, Ingrid, Ley, David, Breakspear, Michael and Vanhatalo, Sampsa (2015). Early detection of preterm intraventricular hemorrhage from clinical electroencephalography. Critical Care Medicine, 43 (10), 2219-2227. doi: 10.1097/CCM.0000000000001190

Optimization of dosing regimens and dosing in special populations

Sime, F. B., Roberts, M. S. and Roberts, J. A. (2015). Optimization of dosing regimens and dosing in special populations. Clinical Microbiology and Infection, 21 (10), 886-893. doi: 10.1016/j.cmi.2015.05.002

Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill

Tsai, Danny, Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill. Current Opinion in Critical Care, 21 (5), 412-420. doi: 10.1097/MCC.0000000000000229

Plasma and peritoneal fluid population pharmacokinetics of micafungin in post-surgical patients with severe peritonitis

Grau, S., Luque, S., Campillo, N., Samso, E., Rodriguez, U., Garcia-Bernedo, C.A., Salas, E., Sharma, R., Hope, W.W. and Roberts, J.A. (2015). Plasma and peritoneal fluid population pharmacokinetics of micafungin in post-surgical patients with severe peritonitis. Journal of Antimicrobial Chemotherapy, 70 (10) dkv173, 2854-2861. doi: 10.1093/jac/dkv173

Population pharmacokinetics of fosfomycin in critically ill patients

Parker, Suzanne L., Frantzeskaki, Frantzeska, Wallis, Steven C., Diakaki, Chryssa, Giamarellou, Helen, Koulenti, Despoina, Karaiskos, Ilias, Lipman, Jeffrey, Dimopoulos, George and Roberts, Jason A. (2015). Population pharmacokinetics of fosfomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (10), 6471-6476. doi: 10.1128/AAC.01321-15

Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling

Parker, Suzanne L., Roberts, Jason A., Lipman, Jeffrey and Wallis, Steven C. (2015). Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling. Bioanalysis, 7 (19), 2585-2595. doi: 10.4155/bio.15.173

Optimizing dosing of antibiotics in critically ill patients

Parker, Suzanne L., Sime, Fekade B. and Roberts, Jason A. (2015). Optimizing dosing of antibiotics in critically ill patients. Current Opinion in Infectious Diseases, 28 (6), 497-504. doi: 10.1097/QCO.0000000000000206

Antimicrobial stewardship in Australian hospitals and other settings

Cairns, Kelly A., Roberts, Jason A., Cotta, Menino O. and Cheng, Allen C. (2015). Antimicrobial stewardship in Australian hospitals and other settings. Infectious Diseases and Therapy, 4 (Supp.1), 27-38. doi: 10.1007/s40121-015-0083-9

Understanding PK/PD

Roberts, Jason A., Taccone, Fabio Silvio. and Lipman, Jeffrey. (2015). Understanding PK/PD. Intensive Care Medicine, 42 (11), 1797-1800. doi: 10.1007/s00134-015-4032-6

Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies

Sime, Fekade Bruck., Roberts, Michael S., Tiong, Ing Soo., Gardner, Julia H., Lehman, Sheila., Peake, Sandra L., Hahn, Uwe., Warner, Morgyn S. and Roberts, Jason A. (2015). Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies. Antimicrobial Agents and Chemotherapy, 59 (9), 5463-5469. doi: 10.1128/AAC.00389-15

An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine

Parker, Suzanne L., Adnan, Syamhanin, Meija, Jenny L. Ordonez, Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2015). An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine. Bioanalysis, 7 (18), 2311-2319. doi: 10.4155/bio.15.143

Factors associated with vancomycin nephrotoxicity in the critically ill

Hanrahan, T. P., Kotapati, C., Roberts, M. J., Rowland, J., Lipman, J., Roberts, J. A. and Udy, A. (2015). Factors associated with vancomycin nephrotoxicity in the critically ill. Anaesthesia and Intensive Care, 43 (5), 594-599. doi: 10.1177/0310057X1504300507

The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs

Tabah, Alexis, De Waele, Jan, Lipman, Jeffrey, Zahar, Jean Ralph, Cotta, Menino Osbert, Barton, Greg, Timsit, Jean-Francois and Roberts, Jason A. (2015). The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs. Journal of Antimicrobial Chemotherapy, 70 (9), 2671-2677. doi: 10.1093/jac/dkv165

Vancomycin-associated nephrotoxicity: a meta-analysis of administration by continuous versus intermittent infusion

Hanrahan, Timothy, Whitehouse, Tony, Lipman, Jeffrey and Roberts, Jason A. (2015). Vancomycin-associated nephrotoxicity: a meta-analysis of administration by continuous versus intermittent infusion. International Journal of Antimicrobial Agents, 46 (3), 249-253. doi: 10.1016/j.ijantimicag.2015.04.013

A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients

Carlier, Mieke, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2015). A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (8), 4689-4694. doi: 10.1128/AAC.00409-15

Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?

Jamal, Janattul-Ain, Udy, Andrew A., Wallis, Steven C., Ranganathan, Dwarakanathan, McWhinney, Brett C., Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2015). Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?. International Journal of Artificial Organs, 38 (8), 419-424. doi: 10.5301/ijao.5000422

Does appropriate antibiotic therapy mean only adequate spectrum and timing?

Lipman, Jeffrey and Roberts, Jason (2015). Does appropriate antibiotic therapy mean only adequate spectrum and timing?. Critical Care Medicine, 43 (8), 1773-1774. doi: 10.1097/CCM.0000000000001060

Enterovirus D68 disease and molecular epidemiology in Australia

Levy, Avram, Roberts, Jason, Lang, Jurissa, Tempone, Simone, Kesson, Alison, Dofai, Alfred, Daley, Andrew J., Thorley, Bruce and Speers, David J. (2015). Enterovirus D68 disease and molecular epidemiology in Australia. Journal of Clinical Virology, 69, 117-121. doi: 10.1016/j.jcv.2015.06.079

The need for cost-effectiveness analyses of antimicrobial stewardship programmes: a structured review

Coulter, Sonali, Merollini, Katharina, Roberts, Jason A., Graves, Nicholas and Halton, Kate (2015). The need for cost-effectiveness analyses of antimicrobial stewardship programmes: a structured review. International Journal of Antimicrobial Agents, 46 (2) 4585, 140-149. doi: 10.1016/j.ijantimicag.2015.04.007

Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review

Carlier, Mieke, Stove, Veronique, Wallis, Steven C., De Waele, Jan J., Verstraete, Alain G., Lipman, Jeffrey and Roberts, Jason A. (2015). Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review. International Journal of Antimicrobial Agents, 46 (4), 367-375. doi: 10.1016/j.ijantimicag.2015.06.016

Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2015). Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis. International Journal of Antimicrobial Agents, 46 (1), 121-124. doi: 10.1016/j.ijantimicag.2015.02.017

Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: a randomised controll edtrial of continuous infusion versus intermittent bolus administration

Jamal, Janattul-Ain, Roberts, Darren M., Udy, Andrew A., Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: a randomised controll edtrial of continuous infusion versus intermittent bolus administration. International Journal of Antimicrobial Agents, 46 (1), 39-44. doi: 10.1016/j.ijantimicag.2015.02.014

Standard dosing of amikacin and gentamicin in critically ill patients results in variable and subtherapeutic concentrations

Roger, Claire, Nucci, Bastian, Molinari, Nicolas, Bastide, Sophie, Saissi, Gilbert, Pradel, Gael, Barbar, Saber, Aubert, Clement, Lloret, Sophie, Elotmani, Loubna, Polge, Anne, Lefrant, Jean-Yves, Roberts, Jason A and Muller, Laurent (2015). Standard dosing of amikacin and gentamicin in critically ill patients results in variable and subtherapeutic concentrations. International Journal of Antimicrobial Agents, 46 (1), 21-27. doi: 10.1016/j.ijantimicag.2015.02.009

Pharmacokinetics and preliminary safety ofhigh dose linezolid for the treatment of Gram-positive bacterial infections

Lopez-Garcia, Belen, Luque, Sonia, Roberts, Jason A. and Grau, Santiago (2015). Pharmacokinetics and preliminary safety ofhigh dose linezolid for the treatment of Gram-positive bacterial infections. Journal of Infection, 71 (5), 604-607. doi: 10.1016/j.jinf.2015.06.007

Microbiologic clearance following transition from standard infusion piperacillin-tazobactam to extended-infusion for persistent Gram-negative bacteremia and possible endocarditis: a case report and review of the literature

D'Agostino, Carly, Rhodes, Nathaniel J., Skoglund, Erik, Roberts, Jason A. and Scheetz, Marc H. (2015). Microbiologic clearance following transition from standard infusion piperacillin-tazobactam to extended-infusion for persistent Gram-negative bacteremia and possible endocarditis: a case report and review of the literature. Journal of Infection and Chemotherapy, 21 (10), 742-746. doi: 10.1016/j.jiac.2015.05.010

Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis

Brink, A. J., Richards, G. A., Lautenbach, E. E. G., Rapeport, N., Schillack, V., van Niekerk, L., Lipman, J. and Roberts, J. A. (2015). Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis. International Journal of Antimicrobial Agents, 45 (6), 647-651. doi: 10.1016/j.ijantimicag.2015.01.015

Australian National Enterovirus Reference Laboratory annual report, 2013

Roberts, Jason A., Hobday, Linda K., Ibrahim, Aishah, Aitkin, Thomas and Thorley, Bruce R. (2015). Australian National Enterovirus Reference Laboratory annual report, 2013. Communicable Diseases Intelligence Quarterly Report, 39 (2), E208-E216.

Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial

Sime, Fekade B., Roberts, Michael S., Tiong, Ing S., Gardner, Julia H., Lehman, Sheila, Peake, Sandra L., Hahn, Uwe, Warner, Morgyn S. and Roberts, Jason A. (2015). Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial. Journal of Antimicrobial Chemotherapy, 70 (8) dkv123, 2369-2375. doi: 10.1093/jac/dkv123

Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients

De Waele, J. J., Lipman, J., Akova, M., Bassetti, M. , Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P. , Rello, J. , Rhodes, A. , Udy, A. A. , Starr, T. , Wallis, S. C. and Roberts, J. A. (2015). Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients. Intensive Care Medicine, 41 (5), 969-969. doi: 10.1007/s00134-015-3772-7

How can we ensure effective antibiotic dosing in critically ill patients receiving different types of renal replacement therapy?

Jamal, Janattul-Ain, Mueller, Bruce A., Choi, Gordon Y. S., Lipman, Jeffrey and Roberts, Jason A. (2015). How can we ensure effective antibiotic dosing in critically ill patients receiving different types of renal replacement therapy?. Diagnostic Microbiology and Infectious Disease, 82 (1), 92-103. doi: 10.1016/j.diagmicrobio.2015.01.013

Vancomycin-associated nephrotoxicity: unintentional consequences of a loading dose? Reply

Hanrahan, Timothy P., Harlow, Georgina, Dulhunty, Joel M., Lipman, Jeffrey, Whitehouse, Tony and Roberts, Jason A. (2015). Vancomycin-associated nephrotoxicity: unintentional consequences of a loading dose? Reply. Critical Care Medicine, 43 (5), E154-E155. doi: 10.1097/CCM.0000000000000952

Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: Results from an ex vivo study

Shekar, Kiran, Roberts, Jason A, Mcdonald, Charles I, Ghassabian, Sussan, Anstey, Chris, Wallis, Steven C, Mullany, Daniel V, Fung, Yoke L and Fraser, John F (2015). Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: Results from an ex vivo study. Critical Care, 19 (164) 164, 164. doi: 10.1186/s13054-015-0891-z

A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics

Roberts, Darren M, Liu, Xin, Roberts, Jason A, Nair, Priya, Cole, Louise, Roberts, Michael S, Lipman, Jeffrey, Bellomo, Rinaldo and RENAL Replacement Therapy Study Investigators (2015). A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics. Critical Care, 19 (84) 84, 84. doi: 10.1186/s13054-015-0818-8

Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients

Wong G., Farkas A., Sussman R., Daroczi G., Hope W.W., Lipman J. and Roberts J.A. (2015). Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (3), 1411-1417. doi: 10.1128/AAC.04001-14

β-Lactam pharmacokinetics during extracorporeal membrane oxygenation therapy: A case-control study

Donadello, Katia, Antonucci, Elio, Cristallini, Stefano, Roberts, Jason A., Beumier, Marjorie, Scolletta, Sabino, Jacobs, Frederique, Rondelet, Benoit, de Backer, Daniel, Vincent, Jean-Louis and Taccone, Fabio Silvio (2015). β-Lactam pharmacokinetics during extracorporeal membrane oxygenation therapy: A case-control study. International Journal of Antimicrobial Agents, 45 (3), 278-282. doi: 10.1016/j.ijantimicag.2014.11.005

Streamlined research funding using short proposals and accelerated peer review: An observational study

Barnett, Adrian G., Herbert, Danielle L., Campbell, Megan, Daly, Naomi, Roberts, Jason A., Mudge, Alison and Graves, Nicholas (2015). Streamlined research funding using short proposals and accelerated peer review: An observational study. BMC Health Services Research, 15 (1) 55. doi: 10.1186/s12913-015-0721-7

A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans

Parker S.L., Lipman J., Roberts J.A. and Wallis S.C. (2015). A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 105, 39-45. doi: 10.1016/j.jpba.2014.11.042

Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study

Sinnollareddy, Mahipal G., Roberts, Jason A., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Dimopoulos, George (2015). Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study. Critical Care, 19 (33) 33, 1-7. doi: 10.1186/s13054-015-0758-3

Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Hope, William W. and Roberts, Jason A. (2015). Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development. Seminars in Respiratory and Critical Care Medicine, 36 (1), 136-153. doi: 10.1055/s-0034-1398490

Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?

Varghese J.M., Jarrett P., Wallis S.C., Boots R.J., Kirkpatrick C.M.J., Lipman J. and Roberts J.A. (2015). Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?. Journal of Antimicrobial Chemotherapy, 70 (2), 528-533. doi: 10.1093/jac/dku413

Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Robertson, Thomas A., Peake, Sandra L. and Roberts, Jason A. (2015). Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. International Journal of Antimicrobial Agents, 45 (2), 192-195. doi: 10.1016/j.ijantimicag.2014.08.013

Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement

Kanji S., Hayes M., Ling A., Shamseer L., Chant C., Edwards D.J., Edwards S., Ensom M.H.H., Foster D.R., Hardy B., Kiser T.H., La Porte C., Roberts J.A., Shulman R., Walker S., Zelenitsky S. and Moher D. (2015). Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement. Clinical Pharmacokinetics, 54 (7), 783-795. doi: 10.1007/s40262-015-0236-8

Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?

Udy, Andrew A., Lipman, Jeffrey, Jarrett, Paul, Klein, Kerenaftali, Wallis, Steven C., Patel, Kashyap, Kirkpatrick, Carl M. J., Kruger, Peter S., Paterson, David L., Roberts, Michael S. and Roberts, Jason A. (2015). Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?. Critical Care, 19 (28) 28, 1-9. doi: 10.1186/s13054-015-0750-y

Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial

Harris, Patrick N. A., Peleg, Anton Y., Iredell, Jon, Ingram, Paul R., Miyakis, Spiros, Stewardson, Andrew J., Rogers, Benjamin A., McBryde, Emma S., Roberts, Jason A., Lipman, Jeff, Athan, Eugene, Paul, Sanjoy K., Baker, Peter, Harris-Brown, Tiffany and Paterson, David L. (2015). Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial. Trials, 16 (1) 24, 24.1-24.8. doi: 10.1186/s13063-014-0541-9

Anti-infective drugs during continuous hemodialysis - using the bench to learn what to do at the bedside

Roehr, Anka C., Frey, Otto R., Koeberer, Andreas, Fuchs, Thomas, Roberts, Jason A. and Brinkmann, Alexander (2015). Anti-infective drugs during continuous hemodialysis - using the bench to learn what to do at the bedside. International Journal of Artificial Organs, 38 (1), 17-22. doi: 10.5301/ijao.5000377

Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring

Cotta, Menino Osbert, Gowen, Belinda, Truloff, Natasha, Bursle, Evan, Mcwhinney, Brett, Ungerer, Jacobus P. J., Roberts, Jason A. and Lipman, Jeffrey (2015). Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring. Infectious Diseases, 47 (10), 739-742. doi: 10.3109/23744235.2015.1021831

Impact of an inducement to give high doses of amikacin and gentamicin on serum concentrations in critically ill patients with severe sepsis

Roger, C., Louart, B., Muller, L., Roberts, J. A. and Lefrant, J. Y. (2015). Impact of an inducement to give high doses of amikacin and gentamicin on serum concentrations in critically ill patients with severe sepsis. Intensive Care Medicine Experimental , 3 A402. doi: 10.1186/2197-425X-3-S1-A402

Linezolid pharmacokinetics in critically ill patients with renal replacement therapy: Comparison of equi-dose of continuous veno-venous haemofiltration with continuous veno-venous haemodiafiltration

Roger, C., Louart, B., Muller, L., Roberts, J. A. and Lefrant, J. Y. (2015). Linezolid pharmacokinetics in critically ill patients with renal replacement therapy: Comparison of equi-dose of continuous veno-venous haemofiltration with continuous veno-venous haemodiafiltration. Intensive Care Medicine Experimental , 3 A631. doi: 10.1186/2197-425X-3-S1-A631

Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: A randomised controlled trial of continuous infusion versus intermittent bolus administration

Jamal, Janattul-Ain, Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Udy, Andrew A., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: A randomised controlled trial of continuous infusion versus intermittent bolus administration. International Journal of Antimicrobial Agents, 45 (1), 41-45. doi: 10.1016/j.ijantimicag.2014.09.009

Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy

Carlier, Mieke, Taccone, Fabio S, Beumier, Majorie, Seyler, Lucie, Cotton, Frederic, Jacobs, Grederique and Roberts, Jason A (2015). Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy. International Journal of Antimicrobial Agents, 46 (4), 413-419. doi: 10.1016/j.ijantimicag.2015.05.020

Subtleties in practical application of prolonged infusion of β-lactam antibiotics

De Waele, J.J., Lipman, J., Carlier, M. and Roberts, J.A. (2015). Subtleties in practical application of prolonged infusion of β-lactam antibiotics. International Journal of Antimicrobial Agents, 45 (5) 4517, 461-463. doi: 10.1016/j.ijantimicag.2015.01.007

Risk factors in hospitalized patients with burn injuries for developing heterotopic ossification—a retrospective analysis

Orchard, Gregory R., Paratz, Jennifer D., Blot, Stijn and Roberts, Jason A. (2014). Risk factors in hospitalized patients with burn injuries for developing heterotopic ossification—a retrospective analysis. Journal of Burn Care and Research, 36 (4), 465-470. doi: 10.1097/BCR.0000000000000123

The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study

Shekar, Kiran, Fraser, John F., Taccone, Fabio Silvio, Welch, Susan, Wallis, Steven C., Mullany, Daniel V., Lipman, Jeffrey and Roberts, Jason A. (2014). The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study. Critical Care, 18 (6) 565, 1-9. doi: 10.1186/s13054-014-0565-2

Decreasing the time to achieve therapeutic vancomycin concentrations in critically ill patients: Developing and testing of a dosing nomogram

Baptista, Joao P., Roberts, Jason A., Sousa, Eduardo, Freitas, Ricardo, Deveza, Nuno and Pimentel, Jorge (2014). Decreasing the time to achieve therapeutic vancomycin concentrations in critically ill patients: Developing and testing of a dosing nomogram. Critical Care, 18 (654) 654, 1-9. doi: 10.1186/s13054-014-0654-2

Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy, 2014

Chau, M. M., Kong, D. C. M., van Hal, S. J., Urbancic, K., Trubiano, J. A., Cassumbhoy, M., Wilkes, J., Cooper, C. M., Roberts, J. A., Marriott, D. J. E. and Worth, L. J. (2014). Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy, 2014. Internal Medicine Journal, 44 (12), 1364-1388. doi: 10.1111/imj.12600

Extended versus bolus infusion of meropenem and piperacillin: a pharmacolcinetic analysis

De Waele, J., Carlier, M., Hoste, E., Depuydt, P., Decruyenaere, J., Wallis, S. C., Lipman, J. and Roberts, J. A. (2014). Extended versus bolus infusion of meropenem and piperacillin: a pharmacolcinetic analysis. Minerva Anestesiologica, 80 (12), 1302-1309.

Therapeutic drug monitoring of antibiotics – author's reply

Roberts, Jason A. (2014). Therapeutic drug monitoring of antibiotics – author's reply. Lancet Infectious Diseases, 14 (12), 1181-1181. doi: 10.1016/S1473-3099(14)71007-2

Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis

Hanrahan, Timothy P., Harlow, Georgina, Hutchinson, James, Dulhunty, Joel M., Lipman, Jeffrey, Whitehouse, Tony and Roberts, Jason A. (2014). Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis. Critical Care Medicine, 42 (12), 2527-2536. doi: 10.1097/CCM.0000000000000514

Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds

Udy, Andrew A., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Starr, Therese, Dunlop, Rachel, Wallis, Steven C., Roberts, Jason A. and Lipman, Jeffrey (2014). Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds. Critical Care, 18 (657) 657, 1-9. doi: 10.1186/s13054-014-0657-z

How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?

Wong, Gloria, Sime, Fekade Bruck, Lipman, Jeffrey and Roberts, Jason A. (2014). How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?. BMC Infectious Diseases, 14 (288) 288, 1-11. doi: 10.1186/1471-2334-14-288

Vancomycin population pharmacokinetics during extracorporeal membrane oxygenation therapy: a matched cohort study

Donadello, Katia, Roberts, Jason A., Cristallini, Stefano, Beumier, Marjorie, Shekar, Kiran, Jacobs, Frederique, Belhaj, Asmae, Vincent, Jean-Louis, de Backer, Daniel and Taccone, Fabio Silvio (2014). Vancomycin population pharmacokinetics during extracorporeal membrane oxygenation therapy: a matched cohort study. Critical Care, 18 (632) 632, 1-10. doi: 10.1186/s13054-014-0632-8

Interethnic differences in pharmacokinetics of antibacterials

Tsai, Danny, Jamal, Janattul-Ain, Davis, Joshua S., Lipman, Jeffrey and Roberts, Jason A. (2014). Interethnic differences in pharmacokinetics of antibacterials. Clinical Pharmacokinetics, 54 (3), 243-260. doi: 10.1007/s40262-014-0209-3

Meeting the challenges of advanced drug delivery in critical illness

Roberts, Jason A. and Fraser, John F. (2014). Meeting the challenges of advanced drug delivery in critical illness. Advanced Drug Delivery Reviews, 77, 1-2. doi: 10.1016/j.addr.2014.11.002

Select critically ill patients at risk of augmented renal clearance: experience in a Malaysian intensive care unit

Adnan, S., Ratnam, S., Kumar, S., Paterson, D., Lipman, J., Roberts, J. and Udy, A. A. (2014). Select critically ill patients at risk of augmented renal clearance: experience in a Malaysian intensive care unit. Anaesthesia And Intensive Care, 42 (6), 715-722. doi: 10.1177/0310057X1404200606

Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU

Abdul-Aziz, Mohd H., McDonald, Craig, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU. Annals of Pharmacotherapy, 48 (10), 1380-1384. doi: 10.1177/1060028014540610

Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures

Carlier, Mieke, Noe, Michael, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2014). Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures. Journal of Antimicrobial Chemotherapy, 69 (10), 2797-2803. doi: 10.1093/jac/dku195

Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al

Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014). Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al. Clinical Infectious Diseases, 59 (6), 907-908. doi: 10.1093/cid/ciu403

Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections

Luque, S., Grau, S., Alvarez-Lerma, F., Ferrandez, O., Campillo, N., Horcajada, J.P., Basas, M., Lipman, J. and Roberts, J.A. (2014). Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections. International Journal of Antimicrobial Agents, 44 (5), 409-415. doi: 10.1016/j.ijantimicag.2014.07.001

How severe is antibiotic pharmacokinetic variability in critically ill patients and what can be done about it?

Felton, T. W., Hope, W. W. and Roberts, J. A. (2014). How severe is antibiotic pharmacokinetic variability in critically ill patients and what can be done about it?. Diagnostic Microbiology and Infectious Disease, 79 (4), 441-447. doi: 10.1016/j.diagmicrobio.2014.04.007

Amikacin dosing in the ICU: we now know more, but still not enough ...

De Rosa, Francesco G. and Roberts, Jason A. (2014). Amikacin dosing in the ICU: we now know more, but still not enough .... Intensive Care Medicine, 40 (7), 1033-1035. doi: 10.1007/s00134-014-3308-6

The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens

Jamal, Janattul-Ain, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2014). The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens. Critical Care Medicine, 42 (7), 1640-1650. doi: 10.1097/CCM.0000000000000317

Micafungin pharmacokinetic/pharmacodynamic adequacy for the treatment of invasive candidiasis in critically ill patients on continuous venovenous haemofiltration

Maseda, Emilio, Grau, Santiago, Villagran, Maria-Jose, Hernandez-Gancedo, Carmen, Lopez-Tofino, Araceli, Roberts, Jason A., Aguilar, Lorenzo, Luque, Sonia, Sevillano, David, Gimenez, Maria-Jose and Gilsanz, Fernando (2014). Micafungin pharmacokinetic/pharmacodynamic adequacy for the treatment of invasive candidiasis in critically ill patients on continuous venovenous haemofiltration. Journal of Antimicrobial Chemotherapy, 69 (6), 1624-1632. doi: 10.1093/jac/dku013

Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies

Sime, Fekade Bruck, Roberts, Michael S., Roberts, Jason A. and Robertson, Thomas A. (2014). Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies. Journal of Chromatography B, 960, 134-144. doi: 10.1016/j.jchromb.2014.04.029

Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?

Nunez-Nunez, Maria, Bellapart, Judith, O’Donoghue, Steven, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?. International journal of antimicrobial agents, 43 (6), 572-573. doi: 10.1016/j.ijantimicag.2014.03.001

Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study

Blot, Stijn, Koulenti, Despoina, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2014). Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study. Critical Care, 18 (3) R99, 1-11. doi: 10.1186/cc13874

Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients

Roberts, Jason A., Udy, Andrew A., Jarrett, Paul, Wallis, Steven C., Hope, William W., Sharma, Raman, Kirkpatrick, Carl M. J., Kruger, Peter S., Roberts, Michael S. and Lipman, Jeffrey (2014). Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients. Journal of Antimicrobial Chemotherapy, 70 (5) dku564, 1495-1502. doi: 10.1093/jac/dku564

An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units

Wong, Gloria, Brinkman, Alexander, Benefield, Russell J., Carlier, Mieke, De Waele, Jan J., Helali, Najoua, Frey, Otto, Harbarth, Stephan, Huttner, Angela, McWhinney, Brett, Misset, Benoit, Pea, Federico, Preisenberger, Judit, Roberts, Michael S., Robertson, Thomas A., Roehr, Anka, Sime, Fekade Bruck, Taccone, Fabio Silvio, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units. Journal of Antimicrobial Chemotherapy, 69 (5) dkt523, 1416-1423. doi: 10.1093/jac/dkt523

The influence of acute kidney injury on antimicrobial dosing in critically ill patients: Are dose reductions always necessary?

Blot,Stijn, Lipman, Jeffrey, Roberts, Darren M. and Roberts, Jason A (2014). The influence of acute kidney injury on antimicrobial dosing in critically ill patients: Are dose reductions always necessary?. Diagnostic Microbiology and Infectious Disease, 79 (1), 77-84. doi: 10.1016/j.diagmicrobio.2014.01.015

DALI: defining antibiotic levels in intensive care unit patients. Are current beta-lactam antibiotic doses sufficient for critically ill patients?

Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014). DALI: defining antibiotic levels in intensive care unit patients. Are current beta-lactam antibiotic doses sufficient for critically ill patients?. Clinical Infectious Diseases, 58 (8), 1072-1083. doi: 10.1093/cid/ciu027

Cefazolin plasma protein binding in different human populations: More than cefazolin-albumin interaction

Smits, Anne, Roberts, Jason A., Vella-Brincat, Jane W. A. and Allegaert, Karel (2014). Cefazolin plasma protein binding in different human populations: More than cefazolin-albumin interaction. International Journal of Antimicrobial Agents, 43 (2), 199-200. doi: 10.1016/j.ijantimicag.2013.10.008

A national survey of renal replacement therapy prescribing practice for acute kidney injury in Malaysian intensive care units

Jamal, Janattul-Ain, Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2014). A national survey of renal replacement therapy prescribing practice for acute kidney injury in Malaysian intensive care units. Nephrology, 19 (8), 507-512. doi: 10.1111/nep.12276

Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy

Sime, Fekade Bruck, Roberts, Michael S., Warner, Morgyn S., Hahn, Uwe, Robertson, Thomas A., Yeend, Sue, Phay, Andy, Lehman, Sheila, Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2014). Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy. Antimicrobial Agents and Chemotherapy, 58 (6), 3533-3537. doi: 10.1128/AAC.02340-14

Antibiotic dosing in critically ill patients with septic shock and on continuous renal replacement therapy: can we resolve this problem with pharmacokinetic studies and dosing guidelines?

Roberts, Jason A. and Roberts, Darren M. (2014). Antibiotic dosing in critically ill patients with septic shock and on continuous renal replacement therapy: can we resolve this problem with pharmacokinetic studies and dosing guidelines?. Critical Care, 18 (3) 156. doi: 10.1186/cc13939

Antimicrobial stewardship activities: a survey of Queensland hospitals

Avent, Minyon L., Hall, Lisa, Davis, Louise, Allen, Michelle, Roberts, Jason A., Unwin, Sean, McIntosh, Kylie A., Thursky, Karin, Buising, Kirsty and Paterson, David L. (2014). Antimicrobial stewardship activities: a survey of Queensland hospitals. Australian Health Review, 38 (5), 557-563. doi: 10.1071/AH13137

Antimicrobial stewardship of β-lactams in intensive care units

Cotta, Menino Osbert, Roberts, Jason A., Tabah, Alexis, Lipman, Jeffrey, Vogelaers, Dirk and Blot, Stijn (2014). Antimicrobial stewardship of β-lactams in intensive care units. Expert Review of Anti-Infective Therapy, 12 (5), 581-595. doi: 10.1586/14787210.2014.902308

Doripenem population pharmacokinetics and dosing requirements for critically ill patients receiving continuous venovenous haemodiafiltration

Roberts, Jason A., Udy, Andrew A., Bulitta, Juergen B., Stuart, Janin, Jarrett, Paul, Starr, Therese, Lassig-Smith, Melissa, Roberts, Natasha A., Dunlop, Rachel, Hayashi, Yoshiro, Wallis, Steven C. and Lipman, Jeffrey (2014). Doripenem population pharmacokinetics and dosing requirements for critically ill patients receiving continuous venovenous haemodiafiltration. Journal of Antimicrobial Chemotherapy, 69 (9) dku177, 2508-2516. doi: 10.1093/jac/dku177

Individualised antibiotic dosing for patients who are critically ill: Challenges and potential solutions

Roberts, Jason A., Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Vinks, Alexander ., Felton, Timothy W., Hope, William W., Farkas, Andras, Neely, Michael N., Schentag, Jerome J., Drusano, George, Frey, Otto R., Theuretzbacher, Ursula and Kuti, Joseph L. (2014). Individualised antibiotic dosing for patients who are critically ill: Challenges and potential solutions. The Lancet Infectious Diseases, 14 (6), 498-509. doi: 10.1016/S1473-3099(14)70036-2

Individualization of piperacillin dosing for critically ill patients: Dosing software to optimize antimicrobial therapy

Felton, T. W., Roberts, J. A., Lodise, T. P., Van Guilder, M., Boselli, E., Neely, M. N. and Hope, W. W. (2014). Individualization of piperacillin dosing for critically ill patients: Dosing software to optimize antimicrobial therapy. Antimicrobial Agents and Chemotherapy, 58 (7), 4094-4102. doi: 10.1128/AAC.02664-14

Pharmacokinetics of piperacillin and tazobactam in plasma and subcutaneous interstitial fluid in critically ill patients receiving continuous venovenous haemodiafiltration

Varghese, Julie M., Jarrett, Paul, Boots, Robert J., Kirkpatrick, Carl M. J., Lipman, Jeffrey and Roberts, Jason A. (2014). Pharmacokinetics of piperacillin and tazobactam in plasma and subcutaneous interstitial fluid in critically ill patients receiving continuous venovenous haemodiafiltration. International Journal of Antimicrobial Agents, 43 (4), 343-348. doi: 10.1016/j.ijantimicag.2014.01.009

Population pharmacokinetics and dose simulation of vancomycin in critically ill patients during high-volume haemofiltration

Escobar, Leslie, Andresen, Max, Downey, Patricio, Gai, Maria Nella, Regueira, Tomas, Borquez, Tamara, Lipman, Jeffrey and Roberts, Jason A. (2014). Population pharmacokinetics and dose simulation of vancomycin in critically ill patients during high-volume haemofiltration. International Journal of Antimicrobial Agents, 44 (2), 163-167. doi: 10.1016/j.ijantimicag.2014.03.009

Preface

Holstege, Gert, Beers, Caroline M. and Subramanian, Hari H. (2014). Preface. Progress in Brain Research, 209, xi-xii. doi: 10.1016/B978-0-444-63488-7.10000-X

Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients

De Waele, Jan J., Lipman, J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Udy, A. A., Starr, T., Wallis, S. C. and Roberts, J. A. (2014). Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients. Intensive Care Medicine, 40 (9), 1340-1351. doi: 10.1007/s00134-014-3403-8

Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DALI Study

Roberts, J. A., Stove, V., De Waele, J. J., Sipinkoski, B., McWhinney, B., Ungerer, J. P. J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, K.-M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Starr, T., Wallis, S. C. and Lipman, J. (2014). Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DALI Study. International Journal of Antimicrobial Agents, 43 (5), 423-430. doi: 10.1016/j.ijantimicag.2014.01.023

Can optimal drug dosing during ECMO improve outcomes?

Shekar, Kiran, Fraser, John F. and Roberts, Jason A. (2013). Can optimal drug dosing during ECMO improve outcomes?. Intensive Care Medicine, 39 (12), 2237-2237. doi: 10.1007/s00134-013-3080-z

Clinical implications of antibiotic pharmacokinetic principles in the critically ill

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2013). Clinical implications of antibiotic pharmacokinetic principles in the critically ill. Intensive Care Medicine, 39 (12), 2070-2082. doi: 10.1007/s00134-013-3088-4

Ampicillin/sulbactam: Its potential use in treating infections in critically ill patients

Adnan, Syamhanin, Paterson, David L., Lipman, Jeffrey and Roberts, Jason A. (2013). Ampicillin/sulbactam: Its potential use in treating infections in critically ill patients. International Journal of Antimicrobial Agents, 42 (5), 384-389. doi: 10.1016/j.ijantimicag.2013.07.012

What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review

Parker, Suzanne, Lipman, Jeffrey, Koulenti, Despoina, Dimopoulos, George and Roberts, Jason A. (2013). What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review. International Journal of Antimicrobial Agents, 42 (4), 289-293. doi: 10.1016/j.ijantimicag.2013.05.018

A protocol for a multicentre randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients with severe sepsis: the BLING II study

Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Udy, Andrew A., Paul, Sanjoy K. and Lipman, Jeffrey (2013). A protocol for a multicentre randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients with severe sepsis: the BLING II study. Critical Care and Resuscitation, 15 (3), 179-185.

Phenytoin loading doses in adult critical care patients: does current practice achieve adequate drug levels?

Putt, M. T., Udy, A. A., Jarrett, P., Martin, J., Hennig, S., Salmon, N., Lipman, J. and Roberts, J. A. (2013). Phenytoin loading doses in adult critical care patients: does current practice achieve adequate drug levels?. Anaesthesia and Intensive Care, 41 (5), 602-609. doi: 10.1177/0310057x1304100505

Electron microscope detection of an endogenous infection of retrovirus-like particles in L20B cells

Roberts, Jason A., Thorley, Bruce R., Bruggink, Leesa D. and Marshall, John A. (2013). Electron microscope detection of an endogenous infection of retrovirus-like particles in L20B cells. Journal of Electron Microscopy, 62 (4), 485-486. doi: 10.1093/jmicro/dfs133

Reply to Soman et al

Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L. and Lipman, Jeffrey (2013). Reply to Soman et al. Clinical Infectious Diseases, 57 (2), 323-324. doi: 10.1093/cid/cit201

Pharmacokinetics of meropenem and piperacillin in critically ill patients with indwelling surgical drains

Adnan, Syamhanin, Li, Janice Xuanhui, Wallis, Steven C., Rudd, Michael, Jarrett, Paul, Paterson, David L., Lipman, Jeffrey, Udy, Andrew A. and Roberts, Jason A. (2013). Pharmacokinetics of meropenem and piperacillin in critically ill patients with indwelling surgical drains. International Journal of Antimicrobial Agents, 42 (1), 90-93. doi: 10.1016/j.ijantimicag.2013.02.023

Annual report of the Australian National Enterovirus Reference Laboratory 2010-2011

Roberts, Jason, Hobday, Linda, Ibrahim, Aishah, Aitken, Thomas and Thorley, Bruce (2013). Annual report of the Australian National Enterovirus Reference Laboratory 2010-2011. Communicable Diseases Intelligence Quarterly Report, 37 (2), E105-E114.

Annual report of the Australian National Enterovirus Reference Laboratory 2012

Roberts, Jason, Hobday, Linda, Ibrahim, Aishah, Aitken, Thomas and Thorley, Bruce (2013). Annual report of the Australian National Enterovirus Reference Laboratory 2012. Communicable Diseases Intelligence Quarterly Report, 37 (2), E97-E104.

Can population pharmacokinetic modelling guide vancomycin dosing during continuous renal replacement therapy in critically ill patients?

Udy, Andrew A., Covajes, Cecilia, Taccone, Fabio Silvio, Jacobs, Frederique, Vincent, Jean-Louis, Lipman, Jeffrey and Roberts, Jason A. (2013). Can population pharmacokinetic modelling guide vancomycin dosing during continuous renal replacement therapy in critically ill patients?. International Journal of Antimicrobial Agents, 41 (6), 564-568. doi: 10.1016/j.ijantimicag.2013.01.018

Meropenem and piperacillin/tazobactam prescribing in critically ill patients: Does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?

Carlier, Mieke, Carrette, Sofie, Roberts, Jason A., Stove, Veronique, Verstraete, Alain, Hoste, Eric, Depuydt, Pieter, Decruyenaere, Johan, Lipman, Jeffrey, Wallis, Steven C. and De Waele, Jan J. (2013). Meropenem and piperacillin/tazobactam prescribing in critically ill patients: Does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?. Critical Care, 17 (3) R84, R84.1-R84.9. doi: 10.1186/cc12705

Digoxin prescription in the critically ill: an unpredictably loaded problem?

Mrara, B., Roberts, J. A. and Gowardman, J. (2013). Digoxin prescription in the critically ill: an unpredictably loaded problem?. Anaesthesia and Intensive Care, 41 (3), 434-436.

How should we dose antibiotics for pneumonia in the ICU?

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2013). How should we dose antibiotics for pneumonia in the ICU?. Current Opinions in Infectious Diseases, 26 (2), 189-195. doi: 10.1097/QCO.0b013e32835d19e0

Echovirus 19 associated with a case of acute flaccid paralysis

Kesson, Alison M., Choo, Chong Ming, Troedson, Christopher, Thorley, Bruce R. and Roberts, Jason A. (2013). Echovirus 19 associated with a case of acute flaccid paralysis. Journal of Paediatrics and Child Health, 49 (3), E239-E242. doi: 10.1111/jpc.12043

The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

Shekar, Kiran, Roberts, Jason A., Smith, Maree T., Fung, Yoke L. and Fraser, John F. (2013). The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation. BMC Anesthesiology, 13 (1) 7, 7.1-7.10. doi: 10.1186/1471-2253-13-7

Letter to the editor: Application of bayesian methods to the inference of phylogeny for enterovirus surveillance

Roberts, J. A., Hung, A. and Thorley, B. R. (2013). Letter to the editor: Application of bayesian methods to the inference of phylogeny for enterovirus surveillance. Eurosurveillance, 18 (9).

Optimal doripenem dosing simulations in critically ill nosocomial pneumonia patients with obesity, augmented renal clearance and decreased bacterial susceptibility

Roberts, Jason and Lipman, Jeffrey (2013). Optimal doripenem dosing simulations in critically ill nosocomial pneumonia patients with obesity, augmented renal clearance and decreased bacterial susceptibility. Critical Care Medicine, 41 (2), 489-495. doi: 10.1097/CCM.0b013e31826ab4c4

β-Lactam therapeutic drug monitoring in the critically ill: optimising drug exposure in patients with fluctuating renal function and hypoalbuminaemia

Hayashi, Yoshiro, Lipman, Jeffrey, Udy, Andrew A., Ng, Mandy, McWhinney, Brett, Ungerer, Jacobus, Lust, Karin and Roberts, Jason A. (2013). β-Lactam therapeutic drug monitoring in the critically ill: optimising drug exposure in patients with fluctuating renal function and hypoalbuminaemia. International Journal of Antimicrobial Agents, 41 (2), 162-166. doi: 10.1016/j.ijantimicag.2012.10.002

A new regimen for continuous infusion of vancomycin during continuous renal replacement therapy

Beumier, Marjorie, Roberts, Jason A., Kabtouri, Hakim, Hites, Maya, Cotton, Frederic, Wolff, Fleur, Lipman, Jeffrey, Jacobs, Frederique, Vincent, Jean-Louis and Taccone, Fabio Silvio (2013). A new regimen for continuous infusion of vancomycin during continuous renal replacement therapy. Journal of Antimicrobial Chemotherapy, 68 (12) dkt261, 2859-2865. doi: 10.1093/jac/dkt261

A protocol for the pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN): An open-label, randomised controlled trial

Ranganathan, Dwarakanathan, John, George T., Healy, Helen, Roberts, Matthew J., Fassett, Robert G., Lipman, Jeffrey, Kubler, Paul, Ungerer, Jacobus, McWhinney, Brett C., Lim, Aaron, Purvey, Megan, Reyaldeen, Reza and Roberts, Jason A. (2013). A protocol for the pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN): An open-label, randomised controlled trial. BMJ Open, 3 (8) e003511, e003511. doi: 10.1136/bmjopen-2013-003511

Augmented renal clearance in septic and traumatized patients with normal plasma creatinine concentrations: identifying at-risk patients

Udy, Andrew A., Roberts, Jason A., Shorr, Andrew F., Boots, Robert J. and Lipman, Jeffrey (2013). Augmented renal clearance in septic and traumatized patients with normal plasma creatinine concentrations: identifying at-risk patients. Critical Care, 17 (1) R35, R35.1-R35.9. doi: 10.1186/cc12544

Continuous infusion of beta-lactam antibiotics in severe sepsis: a multicentre double-blind, randomised controlled trial

Dulhunty, Joel M., Roberts, Jason A., Webb, Joshua S., Webb, Steve A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David and Lipman, Jeffrey (2013). Continuous infusion of beta-lactam antibiotics in severe sepsis: a multicentre double-blind, randomised controlled trial. Clinical Infectious Diseases, 56 (2), 236-244. doi: 10.1093/cid/cis856

Defining antibiotic dosing in lung infections

Jamal, Janattul-Ain, Abdul-Aziz, Mohd-Hafiz, Lipman, Jeffrey and Roberts, Jason A. (2013). Defining antibiotic dosing in lung infections. Clinical Pulmonary Medicine, 20 (3), 121-128. doi: 10.1097/CPM.0b013e31828fc646

Population pharmacokinetics and dosing simulations of amoxicillin/clavulanic acid in critically ill patients

Carlier, Mieke, Noe, Michael, De Waele, Jan J., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and Roberts, Jason A. (2013). Population pharmacokinetics and dosing simulations of amoxicillin/clavulanic acid in critically ill patients. Journal of Antimicrobial Chemotherapy, 68 (11) dkt240, 2600-2608. doi: 10.1093/jac/dkt240

Protein binding of β-lactam antibiotics in critically Ill patients: can we successfully predict unbound concentrations?

Wong, Gloria, Briscoe, Scott, Adnan, Syamhanin, McWhinney, Brett, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A. (2013). Protein binding of β-lactam antibiotics in critically Ill patients: can we successfully predict unbound concentrations?. Antimicrobial Agents and Chemotherapy, 57 (12), 6165-6170. doi: 10.1128/AAC.00951-13

The clinical relevance of plasma protein binding changes

Roberts, Jason, Pea, Federico and Lipman, Jeffrey (2013). The clinical relevance of plasma protein binding changes. Clinical Pharmacokinetics, 52 (1), 1-8. doi: 10.1007/s40262-012-0018-5

The compatibility of a low concentration of hydrocortisone sodium succinate with selected drugs during a simulated Y-site administration

Semark, Andrew J., Venkatesh, Karthik, McWhinney, Brett C., Pretorius, Carel, Roberts, Jason A., Cohen, Jeremy and Venkatesh, Bala (2013). The compatibility of a low concentration of hydrocortisone sodium succinate with selected drugs during a simulated Y-site administration. Critical Care and Resuscitation, 15 (1), 63-66.

Infusional beta-lactam antibiotics in febrile neutropenia: has the time come?

Abbott, Iain J. and Roberts, Jason A. (2012). Infusional beta-lactam antibiotics in febrile neutropenia: has the time come?. Current Opinion in Infectious Diseases, 25 (6), 619-625. doi: 10.1097/QCO.0b013e32835915c2

Therapeutic drug monitoring when using cefepime in continuous renal replacement therapy: seizures associated with cefepime

Smith, Nicholas L., Freebairn, Ross C., Park, Michael A. J., Wallis, Steven C., Roberts, Jason A. and Lipman, Jeffrey (2012). Therapeutic drug monitoring when using cefepime in continuous renal replacement therapy: seizures associated with cefepime. Critical Care and Resuscitation, 14 (4), 312-315.

ASAP ECMO: antibiotic, sedative and analgesic pharmacokinetics during extracorporeal membrane oxygenation: a multi-centre study to optimise drug therapy during ECMO

Shekar, Kiran, Roberts, Jason A., Welsh, Susan, Buscher, Hergen, Rudham, Sam, Burrows, Fay, Ghassabian, Sussan, Wallis, Steven C., Levkovich, Bianca, Pellegrino, Vin, McGuiness, Shay, Parke, Rachael, Gilder, Eileen, Barnett, Adrian G., Walsham, James, Mullany, Daniel V., Fung, Yoke L., Smith, Maree T. and Fraser, John F. (2012). ASAP ECMO: antibiotic, sedative and analgesic pharmacokinetics during extracorporeal membrane oxygenation: a multi-centre study to optimise drug therapy during ECMO. BMC Anesthesiology, 12 (1) 29, 29.1-29.9. doi: 10.1186/1471-2253-12-29

Characterization of poliovirus variants selected for resistance to the antiviral compound V-073

Liu, Hong-Mei, Roberts, Jason A., Moore, Deborah, Anderson, Barbara, Pallansch, Mark A., Pevear, Daniel C., Collett, Marc S. and Oberste, M. Steven (2012). Characterization of poliovirus variants selected for resistance to the antiviral compound V-073. Antimicrobial Agents and Chemotherapy, 56 (11), 5568-5574. doi: 10.1128/AAC.00539-12

Quantification of seven beta-lactam antibiotics and two beta-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method

Carlier, Mieke, Stove, Veronique, Roberts, Jason A., Van de Velde, Eric, De Waele, Jan J. and Verstraete, Alain G. (2012). Quantification of seven beta-lactam antibiotics and two beta-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method. International Journal of Antimicrobial Agents, 40 (5), 416-422. doi: 10.1016/j.ijantimicag.2012.06.022

Sedation during extracorporeal membrane oxygenation-why more is less

Shekar, K., Roberts, J. A., Ghassabian, S., Mullany, D. V., Ziegenfuss, M., Smith, M. T., Fung, Y. L. and Fraser, J. F. (2012). Sedation during extracorporeal membrane oxygenation-why more is less. Anaesthesia and Intensive Care, 40 (6), 1067-1069.

Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?

Shekar, Kiran, Roberts, Jason A., Ghassabian, Sussan, Mullany, Daniel V., Wallis, Steven C., Smith, Maree T. and Fraser, John F. (2012). Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?. Journal of Antimicrobial Chemotherapy, 68 (3), 726-727. doi: 10.1093/jac/dks435

A method for determining the free (unbound) concentration of ten beta-lactam antibiotics in human plasma using high performance liquid chromatography with ultraviolet detection

Briscoe, Scott E., McWhinney, Brett C., Lipman, Jeffrey, Roberts, Jason A. and Ungerer, Jacobus P. J. (2012). A method for determining the free (unbound) concentration of ten beta-lactam antibiotics in human plasma using high performance liquid chromatography with ultraviolet detection. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 907, 178-184. doi: 10.1016/j.jchromb.2012.09.016

Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation

Shekar, Kiran, Roberts, Jason A., McDonald, Charles I., Fisquet, Stephanie, Barnett, Adrian G., Mullany, Daniel V., Ghassabian, Sussan, Wallis, Steven C., Fung, Yoke L., Smith, Maree T. and Fraser, John F. (2012). Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation. Critical Care, 16 (5) R194, R194.1-R194.7. doi: 10.1186/cc11679

Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation

Jamal, Janattul-Ain, Economou, Caleb J. P., Lipman, Jeffrey and Roberts, Jason A. (2012). Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation. Current Opinion in Critical Care, 18 (5), 460-471. doi: 10.1097/MCC.0b013e32835685ad

Investigation of a predicted N-terminal amphipathic α-helix using atomistic molecular dynamics simulation of a complete prototype poliovirus virion

Roberts, Jason A., Kuiper, Michael J., Thorley, Bruce R., Smooker, Peter M. and Hung, Andrew (2012). Investigation of a predicted N-terminal amphipathic α-helix using atomistic molecular dynamics simulation of a complete prototype poliovirus virion. Journal of Molecular Graphics and Modelling, 38, 165-173. doi: 10.1016/j.jmgm.2012.06.009

Continuous beta-lactam infusion in critically ill patients: the clinical evidence

Abdul-Aziz, Mohd H., Dulhunty, Joel M., Bellomo, Rinaldo, Lipman, Jeffrey and Roberts, Jason A. (2012). Continuous beta-lactam infusion in critically ill patients: the clinical evidence. Annals of Intensive Care, 2 (1) 37, 37. doi: 10.1186/2110-5820-2-37

Characteristics of bloodstream infections in burn patients: an 11-year retrospective study

Patel, Bhavik M., Paratz, Jennifer D., Mallet, Anthony, Lipman, Jeffrey, Rudd, Michael, Muller, Michael J., Paterson, David L. and Roberts, Jason A. (2012). Characteristics of bloodstream infections in burn patients: an 11-year retrospective study. Burns, 38 (5), 685-690. doi: 10.1016/j.burns.2011.12.018

Pharmacokinetics of intraperitoneal gentamicin in peritoneal dialysis patients with peritonitis (GIPD study)

Varghese, Julie M., Roberts, Jason A., Wallis, Steven C., Boots, Robert J., Healy, Helen, Fassett, Robert G., Lipman, Jeffrey and Ranganathan, Dwarakanathan (2012). Pharmacokinetics of intraperitoneal gentamicin in peritoneal dialysis patients with peritonitis (GIPD study). Clinical Journal of the American Society of Nephrology, 7 (8), 1249-1256. doi: 10.2215/CJN.12211211

Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review

Sime, Fekade Bruck, Roberts, Michael S., Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2012). Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review. Annals of Intensive Care, 2 (1) 35, 35.1-35.11. doi: 10.1186/2110-5820-2-35

DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic

Roberts, Jason, De Waele, Jan J., Dimopoulos, George, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven and Lipman, Jeffrey (2012). DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic. BMC Infectious Diseases, 12 (1) 152, 152.1-152.7. doi: 10.1186/1471-2334-12-152

A comparison of pulse contour wave analysis and ultrasonic cardiac output monitoring in the critically ill

Udy, A. A., Altukroni, M., Jarrett, P., Roberts, J. A. and Lipman, J. (2012). A comparison of pulse contour wave analysis and ultrasonic cardiac output monitoring in the critically ill. Anaesthesia and Intensive Care, 40 (4), 631-637. doi: 10.1177/0310057X1204000408

Evaluation of medication-related problems in medication reviews: a comparative perspective

Kaur, Sukhpreet, Roberts, Jason A. and Roberts, Michael S. (2012). Evaluation of medication-related problems in medication reviews: a comparative perspective. Annals of Pharmacotherapy, 46 (7-8), 972-982. doi: 10.1345/aph.1Q694

Subtherapeutic Initial beta-Lactam Concentrations in Select Critically Ill Patients Association Between Augmented Renal Clearance and Low Trough Drug Concentrations

Udy, Andrew A., Varghese, Julie M., Altukroni, Mahdi, Briscoe, Scott, McWhinney, Brett C., Ungerer, Jacobus P., Lipman, Jeffrey and Roberts, Jason A. (2012). Subtherapeutic Initial beta-Lactam Concentrations in Select Critically Ill Patients Association Between Augmented Renal Clearance and Low Trough Drug Concentrations. Chest, 142 (1), 30-39. doi: 10.1378/chest.11-1671

Closing the loop-a colistin clinical study to confirm dosing recommendations from PK/PD modeling

Roberts, Jason A. and Lipman, Jeffrey (2012). Closing the loop-a colistin clinical study to confirm dosing recommendations from PK/PD modeling. Clinical Infectious Diseases, 54 (12), 1727-1729. doi: 10.1093/cid/cis311

Antibiotic therapy of pneumonia in critical care

Dhanani, Jayesg, Roberts, Jason A. and Lipman, Jeffrey (2012). Antibiotic therapy of pneumonia in critical care. Current Respiratory Medicine Reviews, 8 (3), 228-238. doi: 10.2174/157339812800493232

Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions

Shekar, Kiran, Fung, Yoke L., Diab, Sara, Mullany, Daniel V., McDonald, Charles I., Dunster, Kimble R., Fisquet, Stephanie, Platts, David G., Stewart, David, Wallis, Steven C., Smith, Maree T., Roberts, Jason A. and Fraser, John F. (2012). Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions. Critical Care and Resuscitation, 14 (2), 105-111.

Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions

Shekar, Kiran, Fung, Yoke L., Diab, Sara, Mullany, Daniel V., McDonald, Charles I, Dunster, Kimble R., Fisquet, Kimble R, Platts, David G., Stewart, David G, Wallis, Steven C., Smith, Maree T., Roberts, Jason A. and Fraser, John F. (2012). Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions. Critical Care and Resuscitation, 14 (2), 105-111.

What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance

Udy, Andrew A., Roberts, Jason A., De Waele, Jan J., Paterson, David L. and Lipman, Jeffrey (2012). What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance. International Journal of Antimicrobial Agents, 39 (6), 455-457. doi: 10.1016/j.ijantimicag.2012.02.010

beta-Lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: A structured review

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012). beta-Lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: A structured review. Clinical and Experimental Pharmacology and Physiology, 39 (6), 489-496. doi: 10.1111/j.1440-1681.2012.05715.x

The association of picornaviruses with gastroenteritis

Thorley, Bruce R. and Roberts, Jason A. (2012). The association of picornaviruses with gastroenteritis. Microbiology Australia, 33 (2), 82-84.

Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study

Roberts, Darren M., Roberts, Jason A., Roberts, Michael S., Liu, Xin, Nair, Priya, Cole, Louise, Lipman, Jeffrey, Bellomo, Rinaldo and on behalf of the RENAL Replacement Therapy Study Investigators (2012). Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study. Critical Care Medicine, 40 (5), 1523-1528. doi: 10.1097/CCM.0b013e318241e553

Therapeutic drug monitoring of beta-lactam antibiotics in burns patients-A one-year prospective study

Patel, Bhavik M., Paratz, Jennifer, See, Natalie C., Muller, Michael J., Rudd, Michael, Paterson, David, Briscoe, Scott E., Ungerer, Jacobus, McWhinney, Brett C., Lipman, Jeffrey and Roberts, Jason A. (2012). Therapeutic drug monitoring of beta-lactam antibiotics in burns patients-A one-year prospective study. Therapeutic Drug Monitoring, 34 (2), 160-164. doi: 10.1097/FTD.0b013e31824981a6

How to optimise antimicrobial prescriptions in the Intensive Care Unit: principles of individualised dosing using pharmacokinetics and pharmacodynamics

Roberts, Jason A., Joynt, Gavin M., Choi, Gordon Y.S., Gomersall, Charles D. and Lipman, Jeffrey (2012). How to optimise antimicrobial prescriptions in the Intensive Care Unit: principles of individualised dosing using pharmacokinetics and pharmacodynamics. International Journal of Antimicrobial Agents, 39 (3), 187-192. doi: 10.1016/j.ijantimicag.2011.11.002

Pharmacokinetics of beta-lactam antibiotics in patients with intra-abdominal disease: A structured review

Adnan, Syamhanin, Paterson, David, Lipman, Jeffrey, Kumar, Suresh, Li, Janice, Rudd, Michael J and Roberts, Jason (2012). Pharmacokinetics of beta-lactam antibiotics in patients with intra-abdominal disease: A structured review. Surgical Infections, 13 (1), 9-17. doi: 10.1089/sur.2011.046

Antibacterial therapeutic drug monitoring in cerebrospinal fluid: difficulty in achieving adequate drug concentrations

Lonsdale, Dagan O., Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2012). Antibacterial therapeutic drug monitoring in cerebrospinal fluid: difficulty in achieving adequate drug concentrations. Journal of Neurosurgery, 118 (2), 297-301. doi: 10.3171/2012.10.JNS12883

Australian clinical pharmacy award oration

Roberts, Jason (2012). Australian clinical pharmacy award oration. Journal of Pharmacy Practice and Research, 42 (4), 308-310. doi: 10.1002/j.2055-2335.2012.tb00195.x

Continuous infusion vs. bolus dosing: Implications for beta-lactam antibiotics

Abdul-Aziz, Mohd Hafiz, Staatz, C. E., Kirkpatrick, C. M. J., Lipman, J. and Roberts, J. A. (2012). Continuous infusion vs. bolus dosing: Implications for beta-lactam antibiotics. Minerva Anestesiologica, 78 (1), 94-104.

Improving vancomycin prescription in critical illness through a drug use evaluation process: a weight-based dosing intervention study

Li, Janice, Udy, Andrew A., Kirkpatrick, Carl M.J., Lipman, Jeffrey and Roberts,Jason A. (2012). Improving vancomycin prescription in critical illness through a drug use evaluation process: a weight-based dosing intervention study. International Journal of Antimicrobial Agents, 39 (1), 69-72. doi: 10.1016/j.ijantimicag.2011.08.017

Increased sedation requirements in patients receiving extracorporeal membrane oxygenation for respiratory and cardiorespiratory failure

Shekar, K., Roberts, J. A., Mullany, D. V., Corley, A., Fisquet, S., Bull, T. N., Barnett, A. G. and Fraser, J. F. (2012). Increased sedation requirements in patients receiving extracorporeal membrane oxygenation for respiratory and cardiorespiratory failure. Anaesthesia and Intensive Care, 40 (4), 648-655. doi: 10.1177/0310057x1204000411

Pharmacokinetic changes in patients receiving extracorporeal membrane oxygenation

Shekar, Kiran, Fraser, John F., Smith, Maree T. and Roberts, Jason A. (2012). Pharmacokinetic changes in patients receiving extracorporeal membrane oxygenation. Journal of Critical Care, 27 (6), 741.e9-741.e18. doi: 10.1016/j.jcrc.2012.02.013

Therapeutic drug monitoring of antimicrobials

Roberts, Jason A., Norris, Ross, Paterson, David L. and Martin, Jennifer H. (2012). Therapeutic drug monitoring of antimicrobials. British Journal of Clinical Pharmacology, 73 (1), 27-36. doi: 10.1111/j.1365-2125.2011.04080.x

Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review

Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012). Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review. International Journal of Antimicrobial Agents, 39 (1), 1-10. doi: 10.1016/j.ijantimicag.2011.07.013

Importance of Antibiotic Dosing in Critically Ill Patients

Roberts, Jason A. (2011). Importance of Antibiotic Dosing in Critically Ill Patients. Current Pharmaceutical Biotechnology, 12 (12), 1981-1982. doi: 10.2174/138920111798808310

Population pharmacokinetics of fluconazole in critically ill patients receiving continuous venovenous hemodiafiltration - using Monte Carlo Simulations to predict doses for specified pharmacodynamic targets

Patel, Kashyap, Roberts, Jason A., Lipman, Jeffrey, Tett, Susan E., Deldot, Megan E. and Kirkpatrick, Carl M. (2011). Population pharmacokinetics of fluconazole in critically ill patients receiving continuous venovenous hemodiafiltration - using Monte Carlo Simulations to predict doses for specified pharmacodynamic targets. Antimicrobial Agents and Chemotherapy, 55 (12), 5868-5873. doi: 10.1128/AAC.00424-11

Using PK/PD to Optimize Antibiotic Dosing for Critically Ill Patients

Roberts, Jason A. (2011). Using PK/PD to Optimize Antibiotic Dosing for Critically Ill Patients. Current Pharmaceutical Biotechnology, 12 (12), 2070-2079. doi: 10.2174/138920111798808329

Do we understand the impact of altered physiology, consequent interventions and resultant clinical scenarios in the intensive care unit? The antibiotic story

Lipman, J., Udy, A. and Roberts, Jason (2011). Do we understand the impact of altered physiology, consequent interventions and resultant clinical scenarios in the intensive care unit? The antibiotic story. Anaesthesia and Intensive Care, 39 (6), 999-1000. doi: 10.1177/0310057x1103900602

Pharmacokinetic evaluation of fluconazole in critically ill patients

Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Playford, E. Geoffrey, Lipman, Jeffrey and Roberts, Jason A. (2011). Pharmacokinetic evaluation of fluconazole in critically ill patients. Expert Opinion On Drug Metabolism and Toxicology, 7 (11), 1431-1440. doi: 10.1517/17425255.2011.615309

Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery

Douglas, Alexandra, Udy, Andrew A., Wallis, Steven C., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Deans, Renae, Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Medley, Gregory, Lipman, Jeffrey and Roberts, Jason A. (2011). Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery. Antimicrobial Agents and Chemotherapy, 55 (11), 5238-5242. doi: 10.1128/AAC.05033-11

Implications of augmented renal clearance in critically ill patients

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2011). Implications of augmented renal clearance in critically ill patients. Nature Reviews Nephrology, 7 (9), 539-543. doi: 10.1038/nrneph.2011.92

Pitfalls of using estimations of glomerular filtration rate in an intensive care population

Martin, Jennifer H., Fay, Michael F., Udy, Andrew, Roberts, Jason, Kirkpatrick, Carl, Ungerer, Jacobus and Lipman, Jeffrey (2011). Pitfalls of using estimations of glomerular filtration rate in an intensive care population. Internal Medicine Journal, 41 (7), 537-543. doi: 10.1111/j.1445-5994.2009.02160.x

A comparison of estimates of glomerular filtration in critically ill patients with augmented renal clearance

Baptista, Joao P., Udy, Andrew A., Sousa, Eduardo, Pimentel, Jorge, Wang, Lisa, Roberts, Jason A. and Lipman, Jeffrey (2011). A comparison of estimates of glomerular filtration in critically ill patients with augmented renal clearance. Critical Care, 15 (3) R139, 1-8. doi: 10.1186/cc10262

Vancomycin Dosing in Critically Ill Patients: Robust Methods for Improved Continuous-Infusion Regimens

Roberts, Jason A., Taccone, Fabio Silvio, Udy, Andrew A., Vincent, Jean-Louis, Jacobs, Frederique and Lipman, Jeffrey (2011). Vancomycin Dosing in Critically Ill Patients: Robust Methods for Improved Continuous-Infusion Regimens. Antimicrobial Agents and Chemotherapy, 55 (6), 2704-2709. doi: 10.1128/AAC.01708-10

Antibiotic dosing in multiple organ dysfunction syndrome

Ulldemolins, Marta, Roberts, Jason A., Lipman, Jeffrey and Rello, Jordi (2011). Antibiotic dosing in multiple organ dysfunction syndrome. Chest, 139 (5), 1210-1220. doi: 10.1378/chest.10-2371

Pharmacodynamic profiling of intravenous antibiotics against prevalent Gram-negative organisms across the globe: The PASSPORT Program—Asia-Pacific Region

Roberts, Jason A., Kwa, Andrea, Montakantikul, Preecha, Gomersall, Charles, Kuti, Joseph L. and Nicolau, David P. (2011). Pharmacodynamic profiling of intravenous antibiotics against prevalent Gram-negative organisms across the globe: The PASSPORT Program—Asia-Pacific Region. International Journal of Antimicrobial Agents, 37 (3), 225-229. doi: 10.1016/j.ijantimicag.2010.10.024

Sustained low efficiency dialysis allows rational renal replacement therapy, but does it allow rational drug dosing?

Roberts, Jason A., Mehta, Ravindra L. and Lipman, Jeffrey (2011). Sustained low efficiency dialysis allows rational renal replacement therapy, but does it allow rational drug dosing?. Critical Care Medicine, 39 (3), 602-603. doi: 10.1097/CCM.0b013e31820e6a0d

Antibiotic dosing in the 'at risk' critically ill patient: linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients

Roberts, Jason A., Roberts, Michael S., Semark, Andrew, Udy, Andrew A., Kirkpatrick, Carl M.J., Paterson, David L., Roberts, Matthew J., Kruger, Peter and Lipman, Jeffrey (2011). Antibiotic dosing in the 'at risk' critically ill patient: linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients. BMC Anesthesiology, 11 (1) 3, 3.1-3.7. doi: 10.1186/1471-2253-11-3

Monte Carlo simulations: Maximizing antibiotic pharmacokinetic data to optimize clinical practice for critically ill patients

Roberts, Jason, Kirkpatrick, Carl M.J. and Lipman, Jeffrey (2011). Monte Carlo simulations: Maximizing antibiotic pharmacokinetic data to optimize clinical practice for critically ill patients. Journal of Antimicrobial Chemotherapy, 66 (2) dkq449, 227-231. doi: 10.1093/jac/dkq449

The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients

Ulldemolins, Marta, Roberts, Jason A., Rello, Jordi, Paterson, David L. and Lipman, Jeffrey (2011). The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients. Clinical Pharmacokinetics, 50 (2), 99-110. doi: 10.2165/11539220-000000000-00000

Antimicrobial Pharmacokinetic and Pharmacodynamic Issues in the Critically Ill with Severe Sepsis and Septic Shock

Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2011). Antimicrobial Pharmacokinetic and Pharmacodynamic Issues in the Critically Ill with Severe Sepsis and Septic Shock. Critical Care Clinics, 27 (1), 19-34. doi: 10.1016/j.ccc.2010.09.006

Effect of intravenous GLutamine supplementation in Trauma patients receiving enteral nutrition study protocol (GLINT Study): A prospective, blinded, randomised, placebo-controlled clinical trial

Al Balushi, Ruqaiya M., Paratz, Jennifer D., Cohen, Jeremy, Banks, Merrilyn, Dulhunty, Joel, Roberts, Jason A. and Lipman, Jeffrey (2011). Effect of intravenous GLutamine supplementation in Trauma patients receiving enteral nutrition study protocol (GLINT Study): A prospective, blinded, randomised, placebo-controlled clinical trial. BMJ Open, 1 (2) e000334, 1-8. doi: 10.1136/bmjopen-2011-000334

Ganciclovir pharmacokinetics and suggested dosing in continuous venovenous haemodiafiltration

McGloughlin, Steven, Roberts, Jason A., O'Donoghue, Steven, Martin, Jennifer, Briscoe, Scott and Lipman, Jeffrey (2011). Ganciclovir pharmacokinetics and suggested dosing in continuous venovenous haemodiafiltration. International Journal of Antimicrobial Agents, 37 (1), 90-92. doi: 10.1016/j.ijantimicag.2010.10.003

The pharmacokinetics of cefazolin in patients undergoing elective and semi-elective abdominal aortic aneurysm open repair surgery

Douglas, Alexandra, Altukroni, Mahdi, Udy, Andrew A., Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Lipman, Jeffrey and Roberts, Jason A. (2011). The pharmacokinetics of cefazolin in patients undergoing elective and semi-elective abdominal aortic aneurysm open repair surgery. BMC Anesthesiology, 11 (1) 5, 5.1-5.5. doi: 10.1186/1471-2253-11-5

Antimicrobial chemotherapy and lung microdialysis: a review

Dhanani, Jayesh, Roberts, Jason A., Chew, Michelle, Lipman, Jeffrey, Boots, Robert J., Paterson, David L. and Fraser, John F. (2010). Antimicrobial chemotherapy and lung microdialysis: a review. International Journal of Antimicrobial Agents, 36 (6), 491-500. doi: 10.1016/j.ijantimicag.2010.08.013

Optimal antibiotic therapy in the management of the lung of the critically ill

Roberts, Jason, Boots, Robert J. and Lipman, Jeffrey (2010). Optimal antibiotic therapy in the management of the lung of the critically ill. Current Reviews in Respiratory Medicine, 6 (4), 253-263. doi: 10.2174/157339810793563749

Therapeutic drug monitoring of beta-lactams in critically ill patients: Proof of concept

Roberts, Jason A., Ulldemolins, Marta, Roberts, Michael S., McWhinney, Brett, Ungerer, Jacobus, Paterson, David L. and Lipman, Jeffrey (2010). Therapeutic drug monitoring of beta-lactams in critically ill patients: Proof of concept. International Journal of Antimicrobial Agents, 36 (4), 332-339. doi: 10.1016/j.ijantimicag.2010.06.008

A survey of antibiotic prescribing practices in Australian and New Zealand intensive care units

Dulhunty, Joel, Webb, Steven, Paterson, David, Bellomo, Rinaldo, Myburgh, John, Roberts, Jason and Lipman, Jeffrey (2010). A survey of antibiotic prescribing practices in Australian and New Zealand intensive care units. Critical Care and Resuscitation, 12 (3), 162-170.

Annual report of the Australian National Poliovirus Reference Laboratory, 2009

Roberts, Jason A, Hobday, Linda, Polychronopoulos, Sophie, Ibrahim, Aishah and Thorley, Bruce R (2010). Annual report of the Australian National Poliovirus Reference Laboratory, 2009. Communicable diseases intelligence, 34 (3), 277-284.

Using population pharmacokinetics to determine Gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury

Roberts, Jason A., Field, Jonathan, Visser, Adam, Whitbread, Rosemary, Tallot, Mandy, Lipman, Jeffrey and Kirkpatrick, Carl M. J. (2010). Using population pharmacokinetics to determine Gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. Antimicrobial Agents and Chemotherapy, 54 (9), 3635-3640. doi: 10.1128/AAC.00222-10

Flucloxacillin dosing in critically ill patients with hypoalbuminaemia: Special emphasis on unbound pharmacokinetics

Ulldemolins, Marta, Roberts, Jason A., Wallis, Steven C., Rello, Jordi and Lipman, Jeffrey (2010). Flucloxacillin dosing in critically ill patients with hypoalbuminaemia: Special emphasis on unbound pharmacokinetics. Journal of Antimicrobial Chemotherapy, 65 (8) dkq184, 1771-1778. doi: 10.1093/jac/dkq184

Pharmacokinetic evaluation of piperacillin-tazobactam

Hayashi, Yoshiro, Roberts, Jason A., Paterson, David L. and Lipman, Jeffrey (2010). Pharmacokinetic evaluation of piperacillin-tazobactam. Expert Opinion on Drug Metabolism and Toxicology, 6 (8), 1017-1031. doi: 10.1517/17425255.2010.506187

Pharmacokinetics and pharmacodynamics in critically ill patients

Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2010). Pharmacokinetics and pharmacodynamics in critically ill patients. Current Opinion in Anesthesiology, 23 (4), 472-478. doi: 10.1097/ACO.0b013e328339ef0a

Analysis of 12 beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection

McWhinney, Brett C., Wallis, Steven C., Hillister, Tara, Roberts, Jason A., Lipman, Jeffrey and Ungerer, Jacobus P.J. (2010). Analysis of 12 beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878 (22), 2039-2043. doi: 10.1016/j.jchromb.2010.05.027

Meropenem dosing in critically ill patients with sepsis receiving high-volume continuous venovenous hemofiltration

Bilgrami, I., Roberts, J. A., Wallis, S. C., Thomas, J., Davis, J., Fowler, S., Goldrick, P. B. and Lipman, J. (2010). Meropenem dosing in critically ill patients with sepsis receiving high-volume continuous venovenous hemofiltration. Antimicrobial Agents and Chemotherapy, 54 (7), 2974-2978. doi: 10.1128/AAC.01582-09

Optimizing antibiotic use in the intensive care unit

Ulldemolins, Marta, Roberts, Jason A. and Lipman, Jeffrey (2010). Optimizing antibiotic use in the intensive care unit. Clinical Pulmonary Medicine, 17 (4), 162-169. doi: 10.1097/CPM.0b013e3181e47953

Augmented renal clearance in the Intensive Care Unit: An illustrative case series

Udy, Andrew A., Putt, Michael T., Shanmugathasan, Sulochana, Roberts, Jason A. and Lipman, Jeffrey (2010). Augmented renal clearance in the Intensive Care Unit: An illustrative case series. International Journal of Antimicrobial Agents, 35 (6), 606-608. doi: 10.1016/j.ijantimicag.2010.02.013

Meropenem: Focus on its use in serious bacterial infections

Roberts, Jason A., Ulldemolins, Marta and Lipman, Jeffrey (2010). Meropenem: Focus on its use in serious bacterial infections. Clinical Medicine Reviews in Therapeutics, 2, 1-14. doi: 10.4137/CMRT.S4598

Therapeutic drug monitoring of beta-lactams for critically ill patients: Unwarranted or essential?

Roberts, Jason A., Hope, William W. and Lipman, Jeffrey (2010). Therapeutic drug monitoring of beta-lactams for critically ill patients: Unwarranted or essential?. International Journal of Antimicrobial Agents, 35 (5), 419-420. doi: 10.1016/j.ijantimicag.2010.01.022

First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis

Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Dalley, Andrew J. and Lipman, Jeffrey (2010). First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 35 (2), 156-163. doi: 10.1016/j.ijantimicag.2009.10.008

Therapeutic monitoring of vancomycin in adult patients: A consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists

Martin, Jennifer H., Norris, Ross, Barras, Michael, Roberts, Jason, Morris, Ray, Doogue, Matthew and Jones, Graham R. D. (2010). Therapeutic monitoring of vancomycin in adult patients: A consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists. Clinical Biochemist Reviews, 31 (1), 21-24.

Augmented renal clearance: Implications for antibacterial dosing in the critically Ill

Udy, Andrew A., Roberts, Jason A., Boots, Robert J., Paterson, David L. and Lipman, Jeffrey (2010). Augmented renal clearance: Implications for antibacterial dosing in the critically Ill. Clinical Pharmacokinetics, 49 (1), 1-16. doi: 10.2165/11318140-000000000-00000

Optimising intraperitoneal gentamicin dosing in peritoneal dialysis patients with peritonitis (GIPD) study

Ranganathan, Dwarakanathan, Varghese, Julie M., Fassett, Robert G., Lipman, Jeffrey, D'Intini, Vincent, Healy, Helen and Roberts, Jason A. (2009). Optimising intraperitoneal gentamicin dosing in peritoneal dialysis patients with peritonitis (GIPD) study. BMC Nephrology, 10 (1) 42, 1-6. doi: 10.1186/1471-2369-10-42

Clearance of intravenous 5-fluorocytosine during continuous venovenous haemodiafiltration in a patient with hepatosplenic candidiasis

Roberts, Jason A., Udy, Andrew A., O'Donoghue, Stephen, Briscoe, Scott, Paterson, David L. and Lipman, Jeffrey (2009). Clearance of intravenous 5-fluorocytosine during continuous venovenous haemodiafiltration in a patient with hepatosplenic candidiasis. International Journal of Antimicrobial Agents, 34 (4), 383-384. doi: 10.1016/j.ijantimicag.2009.05.005

Midazolam metabolism: Implications for individualised dosing?

Roberts, Jason A., Coulthard, Mark G., Addison, Russell S., Foot, Carole and Lipman, Jeffrey (2009). Midazolam metabolism: Implications for individualised dosing?. Journal of Pharmacy Practice and Research, 39 (3), 198-201. doi: 10.1002/j.2055-2335.2009.tb00452.x

Tissue Distribution of Beta-Lactam Antibiotics: Continuous versus Bolus Dosing

Roberts, JA and Lipman, J (2009). Tissue Distribution of Beta-Lactam Antibiotics: Continuous versus Bolus Dosing. Journal of Pharmacy Practice and Research, 39 (3), 219-222. doi: 10.1002/j.2055-2335.2009.tb00457.x

Dose matters: Dose of antibiotics in the critically ill patient depends on the dose of renal replacement therapy

Roberts, Jason A. and Lipman, Jeffrey (2009). Dose matters: Dose of antibiotics in the critically ill patient depends on the dose of renal replacement therapy. Critical Care Medicine, 37 (8), 2491-2492. doi: 10.1097/CCM.0b013e3181aee840

A systematic review on clinical benefits of continuous administration of [beta]-lactam antibiotics

Roberts, Jason A., Webb, Steven, Paterson, David, Ho, Kwok M. and Lipman, Jeffrey (2009). A systematic review on clinical benefits of continuous administration of [beta]-lactam antibiotics. Critical Care Medicine, 37 (6), 2071-2078. doi: 10.1097/CCM.0b013e3181a0054d

Pharmacokinetic issues for antibiotics in the critically ill patient

Roberts, Jason A. and Lipman, Jeffrey (2009). Pharmacokinetic issues for antibiotics in the critically ill patient. Critical Care Medicine, 37 (3), 840-851. doi: 10.1097/CCM.0b013e3181961bff

Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?

Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?. Critical Care Medicine, 37 (3), 926-933. doi: 10.1097/CCM.0b013e3181968e44

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution. Journal of Antimicrobial Chemotherapy, 64 (1), 142-150. doi: 10.1093/jac/dkp139

You only find what you look for: The importance of high creatinine clearance in the critically ill

Udy, A., Roberts, J. A., Boots, R. J. and Lipman, J. (2009). You only find what you look for: The importance of high creatinine clearance in the critically ill. Anaesthesia and Intensive Care, 37 (1), 11-13. doi: 10.1177/0310057x0903700123

Antibiotic resistance - what's dosing got to do with it?

Roberts, Jason A., Kruger, Peter, Paterson, David L. and Lipman, Jeffrey (2008). Antibiotic resistance - what's dosing got to do with it?. Critical Care Medicine, 36 (8), 2433-2440. doi: 10.1097/CCM.0b013e318180fe62

Better outcomes through continuous infusion of time-dependent antibiotics to critically ill patients?

Roberts, Jason A, Lipman, Jeffrey, Blot, Stijn and Rello, Jordi (2008). Better outcomes through continuous infusion of time-dependent antibiotics to critically ill patients?. Current Opinion in Critical Care, 14 (4), 390-396. doi: 10.1097/MCC.0b013e3283021b3a

Lessons learnt in the pharmacokinetic analysis of the effect of haemoperfusion for acute overdose with sustained-release diltiazem

D. M. Roberts, J. A. Roberts, R. J. Boots, R. Mason and J. Lipman (2008). Lessons learnt in the pharmacokinetic analysis of the effect of haemoperfusion for acute overdose with sustained-release diltiazem. Anaesthesia, 63 (7), 714-718. doi: 10.1111/j.1365-2044.2008.05477.x

Continuous infusion of [beta]-lactams in the intensive care unit—Best way to hit the target?

Jason A. Roberts, Jennifer D. Paratz and Jeffrey Lipman (2008). Continuous infusion of [beta]-lactams in the intensive care unit—Best way to hit the target?. Critical Care Medicine, 36 (5), 1663-1664. doi: 10.1097/CCM.0b013e3181704625

Continuous infusion of time-dependent antibiotics: lung pharmacokinetics and pharmacodynamics

Roberts, Jason A., Paratz, Jennifer D., Paratz, Elizabeth D., Boots, Rob J. and Jeffrey Lipman (2008). Continuous infusion of time-dependent antibiotics: lung pharmacokinetics and pharmacodynamics. Clinical Pulmonary Medicine, 15 (3), 167-172. doi: 10.1097/CPM.0b013e3181729d3d

A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis

Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Cross, Sheree E. and Lipman, Jeffrey (2008). A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis. International Journal of Antimicrobial Agents, 31 (3), 240-244. doi: 10.1016/j.ijantimicag.2007.09.013

Expanding horizons - needs you to travel over them!

Roberts, Jason A. (2007). Expanding horizons - needs you to travel over them!. Journal of Pharmacy Practice and Research, 37 (4), 333-333. doi: 10.1002/j.2055-2335.2007.tb00781.x

Conclusions regarding the efficacy of treatments for neuroleptic malignant syndrome should be tempered given poor quality data, regardless of the analysis conducted

Roberts, Darren M. and Roberts, Jason A. (2007). Conclusions regarding the efficacy of treatments for neuroleptic malignant syndrome should be tempered given poor quality data, regardless of the analysis conducted. Critical Care, 11 (3), 1-2. doi: 10.1186/cc5786

Cefepime versus ceftazidime: Considerations for empirical use in critically ill patients

Roberts, Jason A., Webb, Steven A. R. and Lipman, Jeffrey (2007). Cefepime versus ceftazidime: Considerations for empirical use in critically ill patients. International Journal of Antimicrobial Agents, 29 (2), 117-128. doi: 10.1016/j.ijantimicag.2006.08.031

Is continuous infusion ceftriaxone better than once-a-day dosing in intensive care? A randomized controlled pilot study

Roberts, J. A., Boots, R., Rickard, C. M., Thomas, P., Quinn, J., Roberts, D. M., Richards, B. and Lipman, J. (2007). Is continuous infusion ceftriaxone better than once-a-day dosing in intensive care? A randomized controlled pilot study. Journal of Antimicrobial Chemotherapy, 59 (2), 285-291. doi: 10.1093/jac/dkl478

Continuous infusion of beta-lactam antibiotics in severe infections: a review of its role

Roberts, Jason A., Paratz, Jennifer, Paratz, Elizabeth, Krueger, Wolfgang A. and Lipman, Jeffrey (2007). Continuous infusion of beta-lactam antibiotics in severe infections: a review of its role. International Journal of Antimicrobial Agents, 30 (1), 11-18. doi: 10.1016/j.ijantimicag.2007.02.002

Optimizing use of ß-lactum antibiotics in the critically ill

Roberts, Jason A. and Lipman, Jeffrey (2007). Optimizing use of ß-lactum antibiotics in the critically ill. Seminars in Respiratory and Critical Care Medicine, 28 (6), 579-585. doi: 10.1055/s-2007-996404

Pharmacists investigating adverse penicillin responses - Pilot Study

Roberts, Jason A., Hsu, Millie, Allen, Karen, Willis, Jennifer and Barras, Michael (2007). Pharmacists investigating adverse penicillin responses - Pilot Study. Journal of Pharmacy Practice and Research, 37 (3), 200-203. doi: 10.1002/j.2055-2335.2007.tb00744.x

Antibacterial dosing in intensive care: Pharmacokinetics, degree of disease and pharmacodynamics of sepsis

Roberts, J. A. and Lipman, J. (2006). Antibacterial dosing in intensive care: Pharmacokinetics, degree of disease and pharmacodynamics of sepsis. Clinical Pharmacokinetics, 45 (8), 755-773. doi: 10.2165/00003088-200645080-00001

Toxocara vitulorum: treatment based on the duration of the infectivity of buffalo cows (Bubalus bubalis) for their calves

A.ROBERTS, J. (1989). Toxocara vitulorum: treatment based on the duration of the infectivity of buffalo cows (Bubalus bubalis) for their calves. Journal of Veterinary Pharmacology and Therapeutics, 12 (1), 5-13. doi: 10.1111/j.1365-2885.1989.tb00634.x

Trimethoprim-sulfamethoxazole pharmacokinetic evaluation in adult kidney transplant recipients.

Scuderi, C.E., Parker, S.L., Jacks, M., John, G.T., McWhinney, B., Ungerer, J., Mallett, A.J., Healy, H.G., Roberts, J.A. and Staatz, C.E. (2023). Trimethoprim-sulfamethoxazole pharmacokinetic evaluation in adult kidney transplant recipients.. World Congress on Pharmacy and Pharmaceutical Sciences., Brisbane, QLD Australia, 24-28 September 2023.

In vitro susceptibility testing of imipenem- relebactam and tedizolid against australian mycobacterium abscessus isolates

Burke, A. J., Carter, R., Tolson, C., Congdon, J., Duplancic, C., Bursle, E., Bell, S., Roberts, J. and Thomson, R. (2023). In vitro susceptibility testing of imipenem- relebactam and tedizolid against australian mycobacterium abscessus isolates. ATS 2023 International Conference, Washington, DC USA, 19-24 May 2023. Washington, DC USA: American Thoracic Society. doi: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2968

Demographic, clinical and molecular epidemiology of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli bloodstream infections in Central Australia

Langham, Freya, Tsai, Danny, Camilleri, Shayne, Forde, Brian, Harris, Patrick, Roberts, Jason A. and Chiong, Fabian (2022). Demographic, clinical and molecular epidemiology of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli bloodstream infections in Central Australia. 32nd International Congress of Antimicrobial Chemotherapy (ICC), Perth, WA Australia, 27-30 November 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s2213-7165(22)00286-7

Evaluating mono- and combination therapy of meropenem and amikacin against Pseudomonas aeruginosa bacteremia in the hollow-fiber infection model

Avent, Minyon, Mccarthy, Kate, Sime, Fekade, Naickera, Saiyuri, Heffernan, Aaron, Wallis, Steven, Paterson, David and Roberts, Jason A (2022). Evaluating mono- and combination therapy of meropenem and amikacin against Pseudomonas aeruginosa bacteremia in the hollow-fiber infection model. 32nd International Congress of Antimicrobial Chemotherapy (ICC), Perth, WA, Australia, 27-30 November 2022. Amsterdam, Netherlands: Elsevier . doi: 10.1016/s2213-7165(22)00314-9

Pharmacokinetics of polymyxin B and the pharmacokinetic/pharmacodynamic target attainment in hospitalised adult patients with multidrug-resistant gram-negative infections

Zamri, Puteri Juanita, Abdul-Aziz, Mohd-Hafiz, Hernandez-Mitre, Maria Patricia, Hasan, Mohd Shahnaz, Shariff, Izyani Md, Sulaiman, Helmi, Wallis, Steve, Sumi, Chandra Datta, Sime, Fekade Bruck and Roberts, Jason A (2022). Pharmacokinetics of polymyxin B and the pharmacokinetic/pharmacodynamic target attainment in hospitalised adult patients with multidrug-resistant gram-negative infections. 32nd International Congress of Antimicrobial Chemotherapy (ICC), Perth, Australia, 27-30 November 2022. Amsterdam, Netherlands: Elsevier . doi: 10.1016/s2213-7165(22)00339-3

Tacrolimus, mycophenolate and prednisolone concentration monitoring using microsampling instead of venepuncture in kidney transplant patients

Scuderi, C. E., Parker, S. L., Jacks, M., John, G. T., McWhinney, B., Ungerer, J., Mallett, A. J., Healy, H. G., Roberts, J. A. and Staatz, C. E. (2022). Tacrolimus, mycophenolate and prednisolone concentration monitoring using microsampling instead of venepuncture in kidney transplant patients. Society of Hospital Pharmacists of Australia, Brisbane, QLD, Australia, 1-3 December 2022.

Can microsampling methods replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid and prednisolone concentrations in adult kidney transplant patients?

Scuderi, Carla, Parker, Suzanne, Jacks, Margaret, John, George, McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Healy, Helen, Roberts, Jason and Staatz, Christine (2022). Can microsampling methods replace venepuncture for simultaneous therapeutic drug monitoring of tacrolimus, mycophenolic acid and prednisolone concentrations in adult kidney transplant patients?. 57th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, NSW Australia, 17-19 October 2022. Richmond, VIC Australia: John Wiley & Sons.

Is creatine and tacrolimus measurement through VAMS microsampling the future for adult kidney transplant patients?

Scuderi, C., Parker, S., John, G., McWhinney, B., Ungerer, J., Mallett, A., Roberts, J., Healy, H. and Staatz, C. E. (2022). Is creatine and tacrolimus measurement through VAMS microsampling the future for adult kidney transplant patients? . Australian and New Zealand Society of Nephrology meeting, Sydney, NSW, Australia, October 2022.

Is creatinine and tacrolimus measurement through vams microsampling the future for adault kidney transplant patients?

Scuderi, Carla, Parker, Suzanne, Jacks, Margaret, John, George, Mcwhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Healy, Helen, Roberts, Jason and Staatz, Christine (2022). Is creatinine and tacrolimus measurement through vams microsampling the future for adault kidney transplant patients?. 57th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Australia, 17–19 October 2022. Richmond, VIC, Australia: John Wiley & Sons.

Trimethoprim and sulphathiazole pharmacokinetic evaluation in adult kidney transplant recipients.

Scuderi, C., Jahan, S., Parker, S., Wallis, S., Jacks, M., John, G., McWhinney, B., Ungerer, J., Mallett. A., Healy, H., Roberts, J. and Staatz, C. (2022). Trimethoprim and sulphathiazole pharmacokinetic evaluation in adult kidney transplant recipients. . Society of Hospital Pharmacists of Australia conference, Adelaide, SA Australia, 24-26 February 2022. HOBOKEN: WILEY.

Trimethoprim-sulfamethoxazole pharmacokinetic evaluation in adult kidney transplant patients

Scuderi, C.E., Jahan, S., Parker, S. L., Jacks, M., John, G., McWhinney, B., Ungerer, J., Mallett, A., Healy, H., Roberts, J.A. and Staatz, C. E. (2021). Trimethoprim-sulfamethoxazole pharmacokinetic evaluation in adult kidney transplant patients. Australian and New Zealand Society of Nephrology conference, Virtual, September 2021.

Effect of amoxicillin on oral microcosms in a dynamic reactor

Sulugodu Ramachandra, Srinivas, Sime, Fekade, Naicker, Saiyuri, Han, Pingping, Lee, Ryan, Roberts, Jason and Ivanovski, Sašo (2021). Effect of amoxicillin on oral microcosms in a dynamic reactor. 2021 IADR/AADR/CADR General Session (Virtual Experience), Virtual, 21 July 2021. Alexandria, VA, United States: IADR.

Pharmacodynamic evaluation of intermittent versus prolonged infusion dosing regimens of piperacillin/tazobactam in a hollow-fiber infection model against two susceptible Klebsiella pneumoniae clinical isolates

Sumi, Chandra Datta, B.Sime, Fekade, Heffernan, Aaron J., Naicker, Saiyuri, Islam, Kamrul, Cottrell, Kyra, Harris, Patrick N.A. and Roberts, Jason A. (2020). Pharmacodynamic evaluation of intermittent versus prolonged infusion dosing regimens of piperacillin/tazobactam in a hollow-fiber infection model against two susceptible Klebsiella pneumoniae clinical isolates. Federation of Infection Societies Conference 2019, Edinburgh, United Kingdom, 11-14 November 2019. London, United Kingdom: The Microbiology Society. doi: 10.1099/acmi.fis2019.po0103

Interest in possible alternative methods to venepuncture-based monitoring in kidney transplant patients.

Scuderi, C., Parker, S., John, G., McWhinney, B., Ungerer, J., Mallett, A., Roberts, J., Healy, H. and Staatz, C.E. (2020). Interest in possible alternative methods to venepuncture-based monitoring in kidney transplant patients. . RBWH Symposium, Brisbane, QLD Australia, 7-11 December 2020.

The DECISIVE study: defining beta-lactam concentration in intensive care unit patients – the pharmacokinetics of piperacillin and meropenem in critically ill patients with conserved renal function

Abdul-Aziz, M., Rozali, M., Othman-Jailani, M., Rahman, A. Abd, Sulaiman, H., Atiya, N., Adiraju, S., Wallis, S., Mat, W. Wan, Mazlan, M., Jamaluddin, M., Hasan, M., Mat-Nor, M. and Roberts, J. (2020). The DECISIVE study: defining beta-lactam concentration in intensive care unit patients – the pharmacokinetics of piperacillin and meropenem in critically ill patients with conserved renal function. 31st ICC - 4th GCCMID 2019, Dubai, United Arab Emirates, 6 - 9 November 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jiph.2020.01.129

The burden of venepuncture for kidney transplant patients and interest in possible solutions.

Scuderi, C., Parker, S., John, G., McWhinney, B., Ungerer, J., Mallett, A., Roberts, J., Healy, H. and Staatz, C.E. (2020). The burden of venepuncture for kidney transplant patients and interest in possible solutions. . Society of Hospital Pharmacists of Australia, Online, 21-22 November 2020.

Amikacin loading dose in critically ill patients: designing optimal dosing regimens based on stochastic control

Boidin, C., Bourguignon, L., Cohen, S., Roger, C., Lefrant, J. Y., Roberts, J. A., Allaouchiche, B., Lepape, A., Friggeri, A. and Goutelle, S. (2019). Amikacin loading dose in critically ill patients: designing optimal dosing regimens based on stochastic control. Annual Meeting of French Society of Pharmacology and Therapeutics, and INSERM Clinical Research Centers (CIC) Meeting, Lyon, France, 12–14 June 2019. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Amikacin loading dose in critically ill patients: development of a non-parametric population pharmacokinetic model

Boidin, C., Bourguignon, L., Cohen, S., Roger, C., Lefrant, J. Y., Roberts, J. A., Allaouchiche, B., Lepape, A., Friggeri, A. and Goutelle, S. (2019). Amikacin loading dose in critically ill patients: development of a non-parametric population pharmacokinetic model. Annual Meeting of French Society of Pharmacology and Therapeutics, and INSERM Clinical Research Centers (CIC) Meeting, Lyon, France, 12–14 June 2019. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Optimize cefepime dosing in critically ill patients receiving continuous venovenous hemofiltration

Lin, Hsin, Boidin, Clement, Evans, Danielle, Lopez, Natasha, Healy, Daniel, Serpico, Elena, Goutelle, Sylvain and Roberts, Jason (2019). Optimize cefepime dosing in critically ill patients receiving continuous venovenous hemofiltration. 48th Critical Care Congress of the Society-of-Critical-Care-Medicine, San Diego, CA, United States, 17-20 February 2019. Philadelphia, PA, United States: Lippincott Williams & Wilkins.

Pharmacokinetic dose-approximation significantly increases pharmacokinetic target attainment during the first 24 h of treatment with continuously infused Piperacillin/Tazobactam in critically ill patients

Richter, D. C., Frey, O., Roehr, A., Roberts, J. A., Koeberer, A., Fuchs, Th, Brenner, T., Lichtenstein, C., Weigand, M. A. and Brinkmann, A. (2019). Pharmacokinetic dose-approximation significantly increases pharmacokinetic target attainment during the first 24 h of treatment with continuously infused Piperacillin/Tazobactam in critically ill patients. 9th International Congress ‘‘Sepsis and Multiorgan Dysfunction’’, Weimar, Germany, 11–13 September 2019. Heidelberg, Germany: Springer.

Therapeutic drug monitoring -guided continuous infusion of Piperacillin/Tazobactam significantly improves pharmacokinetic target-attainment in critically ill patients: a retrospective analysis from four years of clinical experience

Richter, D. C., Frey, O., Rohr, A., Roberts, J. A., Koeberer, A., Fuchs, Th, Brenner, T., Lichtenstein, C., Weigand, M. A. and Brinkmann, A. (2019). Therapeutic drug monitoring -guided continuous infusion of Piperacillin/Tazobactam significantly improves pharmacokinetic target-attainment in critically ill patients: a retrospective analysis from four years of clinical experience. 9th International Congress ‘‘Sepsis and Multiorgan Dysfunction’’, Weimar, Germany, 11–13 September 2019. Heidelberg, Germany: Springer.

Does Cefazolin Prophylaxis During Elective Bariatric Caesarean Section Achieve Therapeutic Concentrations in Plasma and Interstitial Fluid?

Christensen, R., Eley, V. A., Smith, M., Jackson, D., Ryan, R., van Zundert, A., Wallis, S., Lipman, J. and Roberts, J. (2018). Does Cefazolin Prophylaxis During Elective Bariatric Caesarean Section Achieve Therapeutic Concentrations in Plasma and Interstitial Fluid?. The National Scientific Congress of the Australian Society of Anaesthetists, Perth Convention and Exhibition Centre, Perth, Western Australia, 7-10th October 2017. New South Wales, Australia: Australian Society of Anaesthetists.

Does Cefazolin Prophylaxis During Elective Bariatric Surgery Achieve Therapeutic Concentrations in Plasma and Interstitial Fluid?

Ryan, R., Jackson, D. , Eley, V. A., Christensen, R., van Zundert, A ., Wallis, S., Lipman, J. and Roberts, J. (2018). Does Cefazolin Prophylaxis During Elective Bariatric Surgery Achieve Therapeutic Concentrations in Plasma and Interstitial Fluid?. The National Scientific Congress of the Australian Society of Anaesthetists, Perth Convention and Exhibition Centre, Perth, Western Australia, 7-10th October. New South Wales, Australia: The Australian Society of Anaesthetists.

Does dosing of ceftriaxone in critically ill patients on ECMO need to change? A pharmacokinetics study

Cheng, V., Shekar, K., Abdul-Aziz, M. H., Buscher, H., Corley, A., Diehl, A., Gilder, A., Jarrett, P., Lye, I., McGuinness, S., Parke, R., Pellegrino, V., Reynolds, C., Wallis, S. C., Welch, S., Zacharias, D., Fraser, J. F. and Roberts, J. A. (2018). Does dosing of ceftriaxone in critically ill patients on ECMO need to change? A pharmacokinetics study. European Society of Intensive Care Medicine Annual Congress, Paris, France, 20-24 October 2018. Heidelberg, Germany: Springer.

Does dosing of piperacillin-tazobactam in critically ill patients on ECMO need to change? A pharmacokinetics study

Cheng, V., Shekar, K., Abdul-Aziz, M.H., Buscher, H., Corley, A., Diehl, A., Gilder, E., Jarrett, P., Lye, I., McGuinness, S., Parke, R., Pellegrino, V., Reynolds, C., Wallis, S. C., Welch, S., Zacharias, D., Fraser, J. F. and Roberts, J. A. (2018). Does dosing of piperacillin-tazobactam in critically ill patients on ECMO need to change? A pharmacokinetics study. European Society of Intensive Care Medicine Annual Congress, Paris, France, 20-24 October 2018. Heidelberg, Germany: Springer.

Potential posaconazole sequestration during extracorporeal membrane oxygentation: Results from an ex-vivo experiment

Lyster, H., Pitt, T., Maunz, O., Saez, D. Garcia, Tiller, J., Leaver, N., Roberts, J., Shekar, K., Brown, D., Mills, J., Carby, M., Simon, A. and Reed, A. (2017). Potential posaconazole sequestration during extracorporeal membrane oxygentation: Results from an ex-vivo experiment. 37th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT), San Diego, CA United States, 5-8 April 2017. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2017.01.055

Optimization of anti-infective Therapy by Concentration Determination Meropenem Pharmacokinetics in critically ill patients undergoing sustained low-efficiency dialysis (SLED)

Koenig, C., Braune, S. A., Roberts, J. A., Nierhaus, A., Steinmetz, O. M., Baehr, M., Neely, M., Langebrake, C. and Kluge, S. (2016). Optimization of anti-infective Therapy by Concentration Determination Meropenem Pharmacokinetics in critically ill patients undergoing sustained low-efficiency dialysis (SLED). Gemeinsamen Jahrestagung der DGIIN und ÖGIAIN. Der Mensch – ein anspruchsvoller Arbeitsplatz, Berlin, Germany, 8-10 June 2016. Heidelberg, Germany: Springer.

Can therapeutic drug monitoring optimise exposure of piperacillin in febrile neutropenic patients with haematological malignancies? A randomised controlled trial

Sime, F. B., Roberts, M., Tiong, I. S., Gardner, J., Lehman, S., Peake, S., Hahn, U., Warner, M. and Roberts, J. (2015). Can therapeutic drug monitoring optimise exposure of piperacillin in febrile neutropenic patients with haematological malignancies? A randomised controlled trial. 20th Congress of European Hematology Association, Vienna, Austria, 11-14 June 2015. Pavia, Italy: Fondazione Ferrata Storti.

The BLISS Study: Beta-Lactam Infusion in Severe Sepsis- Randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting

Abdul-Aziz, M. H., Sulaiman, H., Mat-Nor, M., Rai, V., Wong, K., Hasan, M., Wallis, S., Lipman, J., Staatz, C. E. and Roberts, J. (2015). The BLISS Study: Beta-Lactam Infusion in Severe Sepsis- Randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting. Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), San Diego, CA United States, 17-21 September 2015.

Plasma and subcutaneous tissue pharmacokinetics of piperacillin in a large cohort of critically ill patients with sepsis

Abdul-Aziz, M., Udy, A., Wallis, S., Roberts, M., Lipman, J. and Roberts, J. (2014). Plasma and subcutaneous tissue pharmacokinetics of piperacillin in a large cohort of critically ill patients with sepsis. European Congress of Clinical Microbiology & Infectious Diseases, Barcelona, Spain, 10-13 May 2014.

The ADMIN-ICU survey: A survey on antimicrobials dosing and monitoring strategies in intensive care units

Tabah, A., Roberts, J., De Waele, J. J., Lipman, J., Zahar, J. R., Cotta, M. O., Barton, G. and Timsit, J. -F. (2014). The ADMIN-ICU survey: A survey on antimicrobials dosing and monitoring strategies in intensive care units. 27th Annual Congress of the European Society of Intensive Care Medicine (ESICM), Barcelona, Spain, 27 September-1 October 2014. Heidelberg, Germany: Springer. doi: 10.1007/s00134-014-3451-0

Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation may cause therapeutic failure

Shekar, K., Mcdonald, C., Fisquet, S., Barnett, A., Ghassabian, S., Fung, L., Roberts, J., Smith, M. and Fraser, J. (2012). Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation may cause therapeutic failure. Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meetin, Brisbane, QLD Australia, 16-19 August 2012. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2012.05.584

ECMO: The clinician's view

Fraser, F., Fung, L., Diab, S., Shekar, S., Platts, D., McDonald, C., I, Panavello, M. S. and Roberts, J. (2012). ECMO: The clinician's view. 32nd International Congress of the International Society of Blood Transfusion in joint cooperation with the 10th Congress of AMMTAC, Cancun, Mexico, 7-12 July 2012. Oxford, United Kingdom: Wiley-Blackwell Publishing.

Is morphine superior to fentanyl for analgesia during extracorporeal membrane oxygenation in adult patients?

Shekar, K., Mcdonald, C., Fisquet, S., Barnett, A., Ghassabian, S., Fung, L., Roberts, J., Smith, M. and Fraser, J. (2012). Is morphine superior to fentanyl for analgesia during extracorporeal membrane oxygenation in adult patients?. Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Brisbane, QLD Australia, 16-19 August 2012. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2012.05.585

Pharmacokinetics of meropenem in critically ill patients with indwelling surgical drains

Adnan, Syamhanin, Li, Janice X., Lipman, Jeffrey, Wallis, Steve C. and Roberts, Jason A. (2012). Pharmacokinetics of meropenem in critically ill patients with indwelling surgical drains. 13th Annual Scientific Meeting Antimicrobials 2012, Brisbane Convention and Exhibition Centre, Brisbane, 23 - 25 February 2012. Brisbane QLD, Australia: Australian Society of Antimicrobial.

Vancomycin Dosing in Critically Ill Patients Using Population Pharmacokinetics to Develop Personalised Dosing Regimens to Achieve Target Concentrations by Continuous Infusion

Roberts, Jason A., Taccone, Fabio Silvio, Udy, Andrew, Vincent, Jean-Louis, Jacobs, Frederique and Lipman, Jeffrey (2010). Vancomycin Dosing in Critically Ill Patients Using Population Pharmacokinetics to Develop Personalised Dosing Regimens to Achieve Target Concentrations by Continuous Infusion. 40th Critical Care Congress, San Diego Ca, Jan 15-19, 2011. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Assessment of adequacy of loading dose of phenytoin (PTN) in adult intensive care patients using population pharmacokinetics

Putt, M. T., Roberts, J. A., Udy, A. A., Martin, J. H., Jarrett, P., Salmon, N. and Lipman, J. (2010). Assessment of adequacy of loading dose of phenytoin (PTN) in adult intensive care patients using population pharmacokinetics. 23rd Annual Meeting of the European Society of Intensive Care Medicine, Barcelona, Spain, 9-13 October 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00134-010-2001-7

Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients

Roberts, D. M., Roberts, M. S., Liu, X., Roberts, J. A., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ESICM 2010: 23rd Annual Meeting of the European Society of Intensive Care Medicine, Barcelona, Spain, 9-13 October, 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00134-010-1999-x

Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients

Roberts, D., Roberts, M., Liu, X., Roberts, J., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ANZSN 2010: 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, WA, Australia, 12-15 September 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1797.2010.01377_1.x

Using Population Pharmacokinetics To Determine Gentamicin Dosing during Extended Daily Diafiltration in Critically Ill Patients with Acute Kidney Injury

Roberts, J. A., Field, J., Visser, A., Whitbread, R., Lipman, J. and Kirkpatrick, C. (2009). Using Population Pharmacokinetics To Determine Gentamicin Dosing during Extended Daily Diafiltration in Critically Ill Patients with Acute Kidney Injury. 22nd Annual Congress of the European Society of Intensive Care Medicine, Vienna, Austria, 11-14 October 2009. NEW YORK: SPRINGER.

A comparative study of Nomogram vs Bayesian approaches to monitoring aminoglycosides

Greenup, L.C., Roberts, J. and Kirkpatrick, C. M. J. (2005). A comparative study of Nomogram vs Bayesian approaches to monitoring aminoglycosides. Joint Meeting of ASCEPT and APSA, Melbourne, 4-7 December, 2005. Australia: Australasian Society of Clinical & Experimental Pharmacologists & Toxicologists.

TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of nafamostat and camostat mesylate randomised clinical trials

Hernández-Mitre, María Patricia, UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia, Morpeth, Susan C., Venkatesh, Balasubramanian, Hills, Thomas E., Davis, Joshua, Mahar, Robert K., McPhee, Grace, Jones, Mark, Totterdell, James, Tong, Steven Y. C. and Roberts, Jason A. (2023). TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of nafamostat and camostat mesylate randomised clinical trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols. doi: 10.37766/inplasy2023.2.0120

Beta-lactam antibiotic dosing in critical care units: bolus vs continuous dosing

Jason Roberts (2008). Beta-lactam antibiotic dosing in critical care units: bolus vs continuous dosing. PhD Thesis, School of Medicine, The University of Queensland.