Dr Chun Xu

NHMRC Early Career Fellow

School of Dentistry
Faculty of Health and Behavioural Sciences
chun.xu@uq.edu.au
+61 7 336 58127

Overview

Dr. Chun Xu received his Ph.D. in Biomedical Engineering and Nanotechnology at The University of Queensland, Australia in 2016. Before that, he got a M.D.S. in Oral and Maxillofacial Surgery and a B.D.S. in Dentistry from Wuhan University, China. He is currently a NHMRC Senior Research Officer and C.J. Martin fellow at The University of Queensland. He has published over 60 peer-reviewed scientific papers in top journals and hold several patents. He also serves as review editor on the editorial board of Nanoscience, Frontiers in Chemistry. He is a member of ISO experts committee for Nanoscience and Nanotechnologies. His reseach interests include the synethesis and application of nanomaterials for biomedical applications.

Qualifications

  • Doctor of Philosophy, The University of Queensland
  • Master of Stomatological Medicine, Wuhan University
  • Bachelor of Medicine, Wuhan University

Publications

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • (2021) Master Philosophy

View all Supervision

Available Projects

  • Osteoporosis affects 1.2 million Australians and will cost $33.6 billion by 2022. This study aims to develop a novel nano-cement platform for custom-designed bone repair in osteoporosis, by using purpose-designed nanomaterials and advanced 3D printing technique. The research findings will lead to the development of a new bone repair strategy, expand knowledge on both biomaterials engineering and osteoporosis treatment, and improve the quality of life of Australians.

  • Nanoparticles possess unique physical, chemical and biological properties due to the nanosize effects and offer various advantages for biomedical applications such as drug delivery and tissue engineering. Mesoporous silica nanoparticles (MSNs) are of special interest due to their good biocompatibility, high stability, rigid framework, well-defined pore structure, easily controllable morphology and tuneable surface chemistry. MSNs based delivery systems offer a promising strategy to improve the drawbacks of traditional therapeutic drugs such as low stability and difficulty of crossing the cell membranes. In this project we will develop novel smart MSNs which enable the loading and delivery of large therapeutic molecules including proteins and genes.

  • Bioceramics scaffold is one of the promising candidates for bone repair and regeneration. This project aims to develop a multifunctional mesoporous bioceramics scaffold with antibiotic/growth factor to repair craniofacial bone defects. The advanced 3D printing technique will be employed to precisely fabricate tissues with designed structures and functions while providing biomimetic microenvironments. The unique design and functionality will improve the life quality of patients with bone defects.

View all Available Projects

Publications

Book Chapter

  • Hosseinpour, Sepanta, Nanda, Ashwin, Lei, Chang, Lowe, Baboucarr, Ye, Qingsong and Xu, Chun (2021). Nanobiomaterials in craniofacial bone regeneration. Advances in Dental Implantology using Nanomaterials and Allied Technology Applications. (pp. 25-52) edited by Ramesh S. Chaughule and Rajesh Dashaputra. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-030-52207-0_2

  • He, Yan, Guastaldi, Fernando, Xu, Chun and Ye, Qingsong (2021). Regenerative Approaches in Orthodontic and Orthopedic Treatment. Regenerative Approaches in Dentistry. (pp. 151-170) Cham, Switzerland: Springer. doi: 10.1007/978-3-030-59809-9_8

  • Cheng, Ning, Wen, Juan, Hitching, Rita, Lei, Chang and Xu, Chun (2021). Tooth Bioengineering and Whole Tooth Regeneration. Regenerative Approaches in Dentistry. (pp. 89-102) Cham, Switzerland: Springer. doi: 10.1007/978-3-030-59809-9_5

Journal Article

Other Outputs

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors:

Completed Supervision

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.

  • Osteoporosis affects 1.2 million Australians and will cost $33.6 billion by 2022. This study aims to develop a novel nano-cement platform for custom-designed bone repair in osteoporosis, by using purpose-designed nanomaterials and advanced 3D printing technique. The research findings will lead to the development of a new bone repair strategy, expand knowledge on both biomaterials engineering and osteoporosis treatment, and improve the quality of life of Australians.

  • Nanoparticles possess unique physical, chemical and biological properties due to the nanosize effects and offer various advantages for biomedical applications such as drug delivery and tissue engineering. Mesoporous silica nanoparticles (MSNs) are of special interest due to their good biocompatibility, high stability, rigid framework, well-defined pore structure, easily controllable morphology and tuneable surface chemistry. MSNs based delivery systems offer a promising strategy to improve the drawbacks of traditional therapeutic drugs such as low stability and difficulty of crossing the cell membranes. In this project we will develop novel smart MSNs which enable the loading and delivery of large therapeutic molecules including proteins and genes.

  • Bioceramics scaffold is one of the promising candidates for bone repair and regeneration. This project aims to develop a multifunctional mesoporous bioceramics scaffold with antibiotic/growth factor to repair craniofacial bone defects. The advanced 3D printing technique will be employed to precisely fabricate tissues with designed structures and functions while providing biomimetic microenvironments. The unique design and functionality will improve the life quality of patients with bone defects.