The University of Queensland

Studying Munc18:Syntaxin interactions using small-angle scattering

Whitten, Andrew E., Jarrott, Russell J., Hu, Shu-Hong, Duff, Anthony P., King, Gordon J., Martin, Jennifer L. and Christie, Michelle P. (2019). Studying Munc18:Syntaxin interactions using small-angle scattering. In SNAREs. Methods in Molecular Biology, vol 1860 (pp. 115-144) New York, NY, United States: Humana Press Inc.. doi:10.1007/978-1-4939-8760-3_7

Study of protein three-dimensional structure and dynamics determination using peptide amide hydrogen/deuterium exchange mass spectrometry (DXMS) and chemical cross-linking with mass spectrometry to constrain molecular modeling

Li, Sheng, Mouradov, Dmitri, King, Gordon, Liu, Tong, Ross, Ian, Kobe, Bostjan, Woods, Virgil L. and Huber, Thomas (2009). Study of protein three-dimensional structure and dynamics determination using peptide amide hydrogen/deuterium exchange mass spectrometry (DXMS) and chemical cross-linking with mass spectrometry to constrain molecular modeling. In Gu, Jenny and Bourne, Phillip E. (Ed.), Structural Bioinformatics 2nd ed. (pp. 171-206) Hoboken, N.J.: Wiley-Blackwell.

Overview of the pipeline for structural and functional characterization of macrophage proteins at the University of Queensland

Meng, Weining, Forwood, Jade K., Guncar, Gregor, Robin, Gautier, Cowieson, Nathan P., Listwan, Pawel, Mouradov, Dmitri, King, Gordon, Ross, lan L., Robinson, Jodie, Puri, Munish, Hill, Justine M., Kellie, Stuart, Huber, Thomas, Hume, David A., Martin, Jennifer L. and Kobe, Bostjan (2008). Overview of the pipeline for structural and functional characterization of macrophage proteins at the University of Queensland. In B. Kobe, M. Guss and T. L. Huber (Ed.), Structural proteomics: High-throughput methods (pp. 577-587) Totowa, NJ, United States: Humana Press.

Protein structure determination using a combination of cross-linking, mass spectrometry, and molecular modeling

Mouradov, Dmitri, King. Gordon, Ross, Ian L., Forwood, Jade K., Hume, David A., Sinz, Andrea, Martin, Jennifer L., Kobe, Bostjan and Huber, Thomas L. (2008). Protein structure determination using a combination of cross-linking, mass spectrometry, and molecular modeling. In Bostjan Kobe, Mitchell Guss and Thomas L. Huber (Ed.), Structural Proteomics: High Throughput Methods (pp. 459-474) Totowa, NJ, United States: Humana Press. doi:10.1007/978-1-60327-058-8_31

Human Corneal and Lens Aldehyde Dehydrogenases

King, G., Hirst, L. W. and Holmes, R. (1999). Human Corneal and Lens Aldehyde Dehydrogenases. In Weiner et al (Ed.), Enzymology and Molecular Biology of Carbonyl Metabolism (pp. 189-197) New York: Kluwer Academic/Plenum.

The atypical thiol-disulfide exchange protein alpha-DsbA2 from Wolbachia pipientis is a homotrimeric disulfide isomerase

Walden, Patricia M., Whitten, Andrew E., Premkumar, Lakshmanane, Halili, Maria A., Heras, Begona, King, Gordon J. and Martin, Jennifer L. (2019) The atypical thiol-disulfide exchange protein alpha-DsbA2 from Wolbachia pipientis is a homotrimeric disulfide isomerase. Acta Crystallographica Section D: Structural Biology, 75 3: 283-295. doi:10.1107/S2059798318018442

Synthesis, racemic x-ray crystallographic, and permeability studies of bioactive orbitides from Jatropha species

Ramalho, Suelem D., Wang, Conan K., King, Gordon J., Byriel, Karl A., Huang, Yen-Hua, Bolzani, Vanderlan S. and Craik, David J. (2018) Synthesis, racemic x-ray crystallographic, and permeability studies of bioactive orbitides from Jatropha species. Journal of Natural Products, 81 11: 2436-2445. doi:10.1021/acs.jnatprod.8b00447

Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins

Christie, Michelle P., Hu, Shu-Hong, Whitten, Andrew E., Rehman, Asma, Jarrott, Russell J., King, Gordon J., Collins, Brett M. and Martin, Jennifer L. (2017) Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins. PloS one, 12 10: 1-16. doi:10.1371/journal.pone.0187302

The nature of the Syntaxin4 C-terminus affects Munc18c-supported SNARE assembly

Rehman, Asma, Hu, Shu-Hong , Tnimov, Zakir, Whitten, Andrew E., King, Gordon J., Jarrott, Russell J., Norwood, Suzanne J., Alexandrov, Kirill, Collins, Brett M., Christie, Michelle P. and Martin, Jennifer L. (2017) The nature of the Syntaxin4 C-terminus affects Munc18c-supported SNARE assembly. PLoS One, 12 8: e0183366. doi:10.1371/journal.pone.0183366

Mirror images of antimicrobial peptides provide reflections on their functions and amyloidogenic properties

Wang, Conan K., King, Gordon J., Conibear, Anne C., Ramos, Mariana C., Chaousis, Stephanie, Henriques, Sonia Troeira and Craik, David J. (2016) Mirror images of antimicrobial peptides provide reflections on their functions and amyloidogenic properties. Journal of American Chemical Society, 138 17: 5706-5713. doi:10.1021/jacs.6b02575

Racemic and quasi-racemic x-ray structures of cyclic disulfide-rich peptide drug scaffolds

Wang, Conan K., King, Gordon J., Northfield, Susan E., Ojeda, Paola G. and Craik, David J. (2014) Racemic and quasi-racemic x-ray structures of cyclic disulfide-rich peptide drug scaffolds. Angewandte Chemie - International Edition, 53 42: 11236-11241. doi:10.1002/anie.201406563

Structure of the Acinetobacter baumannii dithiol oxidase DsbA bound to EF-Tu reveals a novel protein interaction site

Premkumar, Lakshmanane, Kurth, Fabian, Duprez, Wilko, Grøftehauge, Morten K., King, Gordon J., Halili, Maria A., Heras, Begoña and Martin, Jennifer L. (2014) Structure of the Acinetobacter baumannii dithiol oxidase DsbA bound to EF-Tu reveals a novel protein interaction site. Journal of Biological Chemistry, 289 29: 19869-19880. doi:10.1074/jbc.M114.571737

Milligram quantities of homogeneous recombinant full-length mouse Munc18c from Escherichia coli cultures

Rehman, Asma, Jarrott, Russell J., Whitten, Andrew E., King, Gordon J., Hu, Shu-Hong, Christie, Michelle P., Collins, Brett M. and Martin, Jennifer L. (2013) Milligram quantities of homogeneous recombinant full-length mouse Munc18c from Escherichia coli cultures. PloS One, 8 12: e83499.1-e83499.12. doi:10.1371/journal.pone.0083499

Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor

Daly, Norelle L., Thorstholm, Louise, Greenwood, Kathryn P., King, Gordon J., Rosengren, K. Johan, Heras, Begona, Martin, Jennifer L. and Craik, David J. (2013) Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor. Journal of Biological Chemistry, 288 50: 36141-36148. doi:10.1074/jbc.M113.528240

Structural and functional characterization of ScsC, a periplasmic thioredoxin-like protein from Salmonella enterica Serovar typhimurium

Shepherd, Mark, Heras, Begona, Achard, Maud E. S., King, Gordon J., Argente, M. Pilar, Kurth, Fabian, Taylor, Samantha L., Howard, Mark J., King, Nathan P., Schembri, Mark A. and McEwan, Alastair G. (2013) Structural and functional characterization of ScsC, a periplasmic thioredoxin-like protein from Salmonella enterica Serovar typhimurium. Antioxidants and Redox Signaling, 19 13: 1494-1506. doi:10.1089/ars.2012.4939

The Arabidopsis B3 domain protein VERNALIZATION1 is involved in processes essential for development with structural and mutational studies revealing its DNA binding surface

King, Gordon J., Chanson, Aurelie H., McCallum, Emily J., Ohme-Takagi, Masaru, Byriel, Karl, Hill, Justine M., Martin, Jennifer L. and Mylne, Joshua S. (2013) The Arabidopsis B3 domain protein VERNALIZATION1 is involved in processes essential for development with structural and mutational studies revealing its DNA binding surface. Journal of Biological Chemistry, 288 5: 3198-3207. doi:10.1074/jbc.M112.438572

Membrane curvature protein exhibits interdomain flexibility and binds a small GTPase

King, Gordon J., Stoeckli, Jacqueline, Hu, Shu-Hong, Winnen, Brit, Duprez, Wilko G. A., Meoli, Christopher C., Junutula, Jagath R., Jarrott, Russell J., James, David E., Whitten, Andrew E. and Martin, Jennifer L. (2012) Membrane curvature protein exhibits interdomain flexibility and binds a small GTPase. Journal of Biological Chemistry, 287 49: 40996-41006. doi:10.1074/jbc.M112.349803

The weak complex between RhoGAP protein ARHGAP22 and signal regulatory protein 14-3-3 Has 1:2 stoichiometry and a single peptide binding mode

Hu, Shu-Hong, Whitten, Andrew E., King, Gordon J., Jones, Alun, Rowland, Alexander F., James, David E. and Martin, Jennifer L. (2012) The weak complex between RhoGAP protein ARHGAP22 and signal regulatory protein 14-3-3 Has 1:2 stoichiometry and a single peptide binding mode. Plos One, 7 8: 41731-1-41731-11. doi:10.1371/journal.pone.0041731

Low-resolution solution structures of Munc18: Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide

Christie, Michelle P., Whitten, Andrew E., King, Gordon J., Hu, Shu-Hong, Jarrott, Russell J., Chen, Kai-En, Duff, Anthony P., Callow, Philip, Collins, Brett M., James, David E. and Martin, Jennifer L. (2012) Low-resolution solution structures of Munc18: Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide. Proceedings of the National Academy of Sciences of the United States of America, 109 25: 9816-9821. doi:10.1073/pnas.1116975109

Interaction between plate make and protein in protein crystallisation screening

King, Gordon J., Chen, Kai-En, Robin, Gautier, Forwood, Jade K., Heras, Begoña, Thakur, Anil S., Kobe, Bostjan, Blomberg, Simon P. and Martin, Jennifer L. (2009) Interaction between plate make and protein in protein crystallisation screening. PLoS One, 4 11: x-x. doi:10.1371/journal.pone.0007851

Expression, purification and preliminary X-ray diffraction studies of VERNALIZATION1208–341 from Arabidopsis thaliana

King, Gordon, Hill, Justine M., Martin, Jennifer L. and Mylne, Joshua S. (2009) Expression, purification and preliminary X-ray diffraction studies of VERNALIZATION1208–341 from Arabidopsis thaliana. Acta Crystallographica Section F-Structural Biology and Crystallization Communications, 65 3: 291-294. doi:10.1107/S1744309109004217

Identification of Disulfide-containing chemical cross-links in proteins using MALDI-TOF/TOF-MAss spectrometry

King, G. J., Jones, A., Kobe, B., Huber, T., Mouradov, D., Hume, D. A. and Ross, I. L. (2008) Identification of Disulfide-containing chemical cross-links in proteins using MALDI-TOF/TOF-MAss spectrometry. Analytical Chemistry, 80 13: 5036-5043. doi:10.1021/ac702277q

Cortactin adopts a globular conformation and bundles actin into sheets

Cowieson, Nathan P., King, Gordon, Cookson, David, Ross, Ian, Huber, Thomas, Hume, David A., Kobe, Bostjan and Martin, Jennifer L. (2008) Cortactin adopts a globular conformation and bundles actin into sheets. The Journal of Biological Chemistry, 283 23: 16187-16193. doi:10.1074/jbc.M708917200

Cloning, expression, purification and characterization of a DsbA-like protein from Wolbachia pipientis

Kurz, Mareike, Iturbe-Ormaetxe, Inaki, Jarrott, Russell, Cowieson, Nathan, Robin, Gautier, Jones, Alun, King, Gordon J., Frei, Patrick, Glockshuber, Rudi, O'Neill, Scott L., Heras, Begona and Martin, Jennifer L. (2008) Cloning, expression, purification and characterization of a DsbA-like protein from Wolbachia pipientis. Protein Expression and Purification, 59 2: 266-273. doi:10.1016/j.pep.2008.02.008

Exiguaquinol: A novel Pentacyclic Hydroquinone from Neopetrosia exigua that inhibits Helicobacter pylori MurI

de Almeida Leone, Priscila, Carroll, Anthony R., Towerzey, Leanne, King, Gordon, McArdle, Bernadette M., Kern, Gunther, Fisher, Stewart, Hooper, John N. A. and Quinn, Ronald J. (2008) Exiguaquinol: A novel Pentacyclic Hydroquinone from Neopetrosia exigua that inhibits Helicobacter pylori MurI. Organic Letters, 10 12: 2585-2588. doi:10.1021/ol800898z

Latifolians A and B, Novel JNK3 Kinase Inhibitors from the Papua New Guinean Plant Gnetum latifolium

Rochfort, Simone J., Towerzey, Leanne, Carroll, Anthony, King, Gordon, Michael, Adam, Pierens, Greg, Rali, Topul, Redburn, Joanne, Whitmore, Jaqueline and Quinn, Ronald J. (2005) Latifolians A and B, Novel JNK3 Kinase Inhibitors from the Papua New Guinean Plant Gnetum latifolium. Journal of Natural Products, 68 7: 1080-1082. doi:10.1021/np049616i

Cheilanthane sesterterpenes, protein kinase inhibitors, from a marine sponge of the genus Ircinia

Buchanan, Malcolm S., Edser, Annette, King, Gordon, Whitmore, Jacqueline and Quinn, Ronald J. (2001) Cheilanthane sesterterpenes, protein kinase inhibitors, from a marine sponge of the genus Ircinia. Journal of Natural Products, 64 3: 300-303. doi:10.1021/np0004597

Covalent modification of sheep liver cytosolic aldehyde dehydrogenase by the oxidative addition of coloured phenoxazine, phenothiazine and phenazine derivatives

Kitson, TM, Kitson, KE and King, GJ (1999) Covalent modification of sheep liver cytosolic aldehyde dehydrogenase by the oxidative addition of coloured phenoxazine, phenothiazine and phenazine derivatives. Enzymology and Molecular Biology of Carbonyl Metabolism 7, 463 89-96.

Human corneal and lens aldehyde dehydrogenases - Localization and function(s) of ocular ALDH1 and ALDH3 isozymes

King, G, Hirst, L and Holmes, R (1999) Human corneal and lens aldehyde dehydrogenases - Localization and function(s) of ocular ALDH1 and ALDH3 isozymes. Enzymology and Molecular Biology of Carbonyl Metabolism 7, 463 189-198.

Reaction between sheep liver mitochondrial aldehyde dehydrogenase and a chromogenic 'reporter group' reagent

King, GJ, Norris, GE, Kitson, KE and Kitson, TM (1999) Reaction between sheep liver mitochondrial aldehyde dehydrogenase and a chromogenic 'reporter group' reagent. Enzymology and Molecular Biology of Carbonyl Metabolism 7, 463 107-113.

Human ocular aldehyde dehydrogenase isozymes: Distribution and properties as major soluble proteins in cornea and lens

King, G and Holmes, R (1998) Human ocular aldehyde dehydrogenase isozymes: Distribution and properties as major soluble proteins in cornea and lens. Journal of Experimental Zoology, 282 1-2: 12-17.

Jack bean urease: mixed-metal derivatives

King, Gordon J. and Zerner, Burt (1997) Jack bean urease: mixed-metal derivatives. Inorganica Chimica Acta, 255 2: 381-388. doi:10.1016/S0020-1693(96)05402-3

Inhibition of chicken liver carboxylesterase by activated carbonyls and carbonyl hydrates

Berndt M.C., Bowles M.R., King G.J. and Zerner B. (1996) Inhibition of chicken liver carboxylesterase by activated carbonyls and carbonyl hydrates. Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology, 1298 2: 159-166. doi:10.1016/S0167-4838(96)00117-3

New catalytic roles for serine esterases: A 19F-NMR study of the interaction of 3,3,3-trifluoro-2,2-dihydroxy-1-phenyl-1-propanone with chicken liver carboxylesterase

Bowles M.R., King G.J., Berndt M.C. and Zerner B. (1996) New catalytic roles for serine esterases: A 19F-NMR study of the interaction of 3,3,3-trifluoro-2,2-dihydroxy-1-phenyl-1-propanone with chicken liver carboxylesterase. Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology, 1298 2: 167-179. doi:10.1016/S0167-4838(96)00116-1

Human Corneal Aldehyde Dehydrogenase - Purification, Kinetic Characterization and Phenotypic Variation

King, G and Holmes, RS (1993) Human Corneal Aldehyde Dehydrogenase - Purification, Kinetic Characterization and Phenotypic Variation. Biochemistry and Molecular Biology International, 31 1: 49-63.

Triethyloxonium Tetrafluoroborate as An Ethylating Agent in Aqueous-Solution

King, GJ, Gazzola, C, Blakeley, RL and Zerner, B (1986) Triethyloxonium Tetrafluoroborate as An Ethylating Agent in Aqueous-Solution. Inorganic Chemistry, 25 8: 1078-1078. doi:10.1021/ic00228a003

Gamma-Carboxyglutamic Acid in Invertebrates - its Identification in Hermatypic Corals

Hamilton, SE, King, G, Tesch, D, Riddles, PW, Keough, DT, Jell, J and Zerner, B (1982) Gamma-Carboxyglutamic Acid in Invertebrates - its Identification in Hermatypic Corals. Biochemical and Biophysical Research Communications, 108 2: 610-613. doi:10.1016/0006-291X(82)90872-5

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

Berry, R., Pang, S., Chen, Z., Kjer-Nielsen, L., Perugini, M., King, G., Wang, C., Chew, S., La Gruta, N., Williams, N., Beddoe, T., Tiganis, T., Cowieson, N., Godfrey, D., Purcell, T., Wilce, M., McCluskey, J. and Rossjohn, J. (2012). The structural basis for autonomous dimerization of the pre-T-cell antigen receptor. In: 22nd IUBMB & 37th FEBS Congress. 22nd IUBMB Congress/37th FEBS Congress, Seville, Spain, (431-431). 4-9 September 2012. doi:10.1111/j.1742-4658.2010.08705.x

Application of bioinformatic/biochemical hybrid approach to determine the structure of protein complexes and multi-domain proteins

Mouradov, D. A., Forwood, J. K., Ross, I. L., King, G. F., Sinz, A., Kobe, B. and Huber, T. L. (2006). Application of bioinformatic/biochemical hybrid approach to determine the structure of protein complexes and multi-domain proteins. In: ComBio 2006 : combined conference abstracts, Brisbane Convention Centre, Brisbane, Queensland, 24 September to 28 September 2006. ComBio 2006, Brisbane, Australia, (). 24-28 September, 2006.

Rapid identification of DTSSP crosslinked peptides using LCMALDI Tof-Tof mass spectrometry

King, G. F., Jones, A., Cowieson, N. P., Huber, T. L., Kobe, B. and Ross, I. L. (2006). Rapid identification of DTSSP crosslinked peptides using LCMALDI Tof-Tof mass spectrometry. In: ComBio 2006. ComBio 2006, Brisbane, Australia, (). 24-28 Sept, 2006.

Human corneal and lens aldehyde dehydrogenases - Purification and properties of human lens ALIDH1 and differential expression as major soluble proteins in human lens (ALDH1) and cornea (ALDH3)

King, G and Holmes, R (1997). Human corneal and lens aldehyde dehydrogenases - Purification and properties of human lens ALIDH1 and differential expression as major soluble proteins in human lens (ALDH1) and cornea (ALDH3). In: Weiner, H, Lindahl, R, Crabb, DW and Flynn, TG, Enzymology and Molecular Biology of Carbonyl Metabolism 6. 8th International Workshop on Enzymology and Molecular Biology of Carbonyl Metabolism, Deadwood Sd, (19-27). Jun 29-Jul 03, 1996.