The University of Queensland

Journal Article

• MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography

  Clabbers, Max T. B., Holmes, Susannah, Muusse, Timothy W., Vajjhala, Parimala R., Thygesen, Sara J., Malde, Alpeshkumar K., Hunter, Dominic J. B., Croll, Tristan I., Flueckiger, Leonie, Nanson, Jeffrey D., Rahaman, Md. Habibur, Aquila, Andrew, Hunter, Mark S., Liang, Mengning, Yoon, Chun Hong, Zhao, Jingjing, Zatsepin, Nadia A., Abbey, Brian, Sierecki, Emma, Gambin, Yann, Stacey, Katryn J., Darmanin, Connie, Kobe, Bostjan, Xu, Hongyi and Ve, Thomas (2021). MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography. Nature Communications, 12 (1) 2578, 1-14. doi: 10.1038/s41467-021-22590-6

• SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration

  Figley, Matthew D., Gu, Weixi, Nanson, Jeffrey D., Shi, Yun, Sasaki, Yo, Cunnea, Katie, Malde, Alpeshkumar K., Jia, Xinying, Luo, Zhenyao, Saikot, Forhad K., Mosaiab, Tamim, Masic, Veronika, Holt, Stephanie, Hartley-Tassell, Lauren, McGuinness, Helen Y., Manik, Mohammad K., Bosanac, Todd, Landsberg, Michael J., Kerry, Philip S., Mobli, Mehdi, Hughes, Robert O., Milbrandt, Jeffrey, Kobe, Bostjan, DiAntonio, Aaron and Ve, Thomas (2021). SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration. Neuron, 109 (7), 1-19. doi: 10.1016/j.neuron.2021.02.009

• Structural basis for nuclear import selectivity of pioneer transcription factor SOX2

  Jagga, Bikshapathi, Edwards, Megan, Pagin, Miriam, Wagstaff, Kylie M., Aragão, David, Roman, Noelia, Nanson, Jeffrey D., Raidal, Shane R., Dominado, Nicole, Stewart, Murray, Jans, David A., Hime, Gary R., Nicolis, Silvia K., Basler, Christopher F. and Forwood, Jade K. (2021). Structural basis for nuclear import selectivity of pioneer transcription factor SOX2. Nature Communications, 12 (1) 28, 1-11. doi: 10.1038/s41467-020-20194-0

• Structure, function, and regulation of thioesterases

  Swarbrick, Crystall M.D., Nanson, Jeffrey D., Patterson, Edward I. and Forwood, Jade K. (2020). Structure, function, and regulation of thioesterases. Progress in Lipid Research, 79 101036, 101036. doi: 10.1016/j.plipres.2020.101036

• Structural characterisation of β-Ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites

  Patterson, Edward I., Nanson, Jeffrey D., Abendroth, Jan, Bryan, Cassie, Sankaran, Banumathi, Myler, Peter J. and Forwood, Jade K. (2020). Structural characterisation of β-Ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites. Proteins: Structure, Function, and Bioinformatics, 88 (1) prot.25765, 47-56. doi: 10.1002/prot.25765

• Structural characterization of a short-chain dehydrogenase/reductase from multi-drug resistant Acinetobacter baumannii

  Cross, Emily M., Aragão, David, Smith, Kate M., Shaw, Karli I., Nanson, Jeffrey D., Raidal, Shane R. and Forwood, Jade K. (2019). Structural characterization of a short-chain dehydrogenase/reductase from multi-drug resistant Acinetobacter baumannii. Biochemical and Biophysical Research Communications, 518 (3), 465-471. doi: 10.1016/j.bbrc.2019.08.056

• NAD+ cleavage activity by animal and plant TIR domains in cell death pathways

  Horsefield, Shane, Burdett, Hayden, Zhang, Xiaoxiao, Manik, Mohammad K., Shi, Yun, Chen, Jian, Qi, Tiancong, Gilley, Jonathan, Lai, Jhih-Siang, Rank, Maxwell X., Casey, Lachlan W., Gu, Weixi, Ericsson, Daniel J., Foley, Gabriel, Hughes, Robert O., Bosanac, Todd, von Itzstein, Mark, Rathjen, John P., Nanson, Jeffrey D., Boden, Mikael, Dry, Ian B., Williams, Simon J., Staskawicz, Brian J., Coleman, Michael P., Ve, Thomas, Dodds, Peter N. and Kobe, Bostjan (2019). NAD+ cleavage activity by animal and plant TIR domains in cell death pathways. Science, 365 (6455), 793-799. doi: 10.1126/science.aax1911

• Death, TIR, and RHIM: Self-assembling domains involved in innate immunity and cell-death signaling

  Nanson, Jeffrey D., Kobe, Bostjan and Ve, Thomas (2019). Death, TIR, and RHIM: Self-assembling domains involved in innate immunity and cell-death signaling. Journal of Leukocyte Biology, 105 (2), 363-375. doi: 10.1002/JLB.MR0318-123R

• Regulation of signaling by cooperative assembly formation in mammalian innate immunity signalosomes by molecular mimics

  Nanson, Jeffrey D., Rahaman, Habibur, Ve, Thomas and Kobe, Bostjan (2018). Regulation of signaling by cooperative assembly formation in mammalian innate immunity signalosomes by molecular mimics. Seminars in Cell and Developmental Biology, 99, 96-114. doi: 10.1016/j.semcdb.2018.05.002

• Structural characterisation of the fatty acid biosynthesis enzyme FabF from the pathogen Listeria monocytogenes

  Soares Da Costa, Tatiana P., Nanson, Jeffrey D. and Forwood, Jade K. (2017). Structural characterisation of the fatty acid biosynthesis enzyme FabF from the pathogen Listeria monocytogenes. Scientific Reports, 7 (1) 39277, 39277. doi: 10.1038/srep39277

• Structural characterisation of FabG from yersinia pestis, a key component of bacterial fatty acid synthesis

  Nanson, Jeffrey D. and Forwood, Jade K. (2015). Structural characterisation of FabG from yersinia pestis, a key component of bacterial fatty acid synthesis. PloS One, 10 (11) e0141543, e0141543. doi: 10.1371/journal.pone.0141543

• Structural characterisation of the Beta-Ketoacyl-Acyl carrier protein synthases, FabF and FabH, of Yersinia pestis

  Nanson, Jeffrey D., Himiari, Zainab, Swarbrick, Crystall M. D. and Forwood, Jade K. (2015). Structural characterisation of the Beta-Ketoacyl-Acyl carrier protein synthases, FabF and FabH, of Yersinia pestis. Scientific Reports, 5 (1) 14797. doi: 10.1038/srep14797

• Structural basis for regulation of the human acetyl-CoA thioesterase 12 and interactions with the steroidogenic acute regulatory protein-related lipid transfer (START) domain

  Swarbrick, Crystall M. D., Roman, Noelia, Cowieson, Nathan, Patterson, Edward I., Nanson, Jeffrey, Siponen, Marina I., Berglund, Helena, Lehtio, Lari and Forwood, Jade K. (2014). Structural basis for regulation of the human acetyl-CoA thioesterase 12 and interactions with the steroidogenic acute regulatory protein-related lipid transfer (START) domain. Journal of Biological Chemistry, 289 (35), 24263-24274. doi: 10.1074/jbc.M114.589408

• Crystallization and preliminary X-ray diffraction analysis of FabG from Yersinia pestis

  Nanson, Jeffrey David and Forwood, Jade Kenneth (2014). Crystallization and preliminary X-ray diffraction analysis of FabG from Yersinia pestis. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 70 (1), 101-104. doi: 10.1107/S2053230X13033402