Journal Article: A nucleotide analog prevents colitis associated cancer via Β-catenin independently of inflammation and autophagy
Sheng, Yong Hua, Giri, Rabina, Davies, Julie, Schreiber, Veronika, Alabbas, Saleh, Movva, Ramya, He, Yaowu, Wu, Andy, Hooper, John, McWhinney, Brett, Oancea, Iulia, Kijanka, Gregor, Hasnain, Sumaira, Lucke, Andrew J., Fairlie, David P., McGuckin, Michael A., Florin, Timothy H. and Begun, Jakob (2021). A nucleotide analog prevents colitis associated cancer via Β-catenin independently of inflammation and autophagy. Cellular and Molecular Gastroenterology and Hepatology, 11 (1), 33-53. doi: 10.1016/j.jcmgh.2020.05.012
Journal Article: IgM and IgA augmented autoantibody signatures improve early‐stage detection of colorectal cancer prior to nodal and distant spread
Roney, Md Saiful Islam, Lanagan, Catharine, Sheng, Yong Hua, Lawler, Karen, Schmidt, Christopher, Nguyen, Nam‐Trung, Begun, Jakob and Kijanka, Gregor Stefan (2021). IgM and IgA augmented autoantibody signatures improve early‐stage detection of colorectal cancer prior to nodal and distant spread. Clinical and Translational Immunology, 10 (9) e1330, e1330. doi: 10.1002/cti2.1330
Journal Article: Microfluidic array chip for parallel detection of waterborne bacteria
Gorgannezhad, Lena, Sreejith, Kamalalayam, Zhang, Jun, Kijanka, Gregor, Christie, Melody, Stratton, Helen and Nguyen, Nam-Trung (2019). Microfluidic array chip for parallel detection of waterborne bacteria. Micromachines, 10 (12) 883, 883. doi: 10.3390/mi10120883
(2018) Mater Foundation
Purchase of Odyssey CLx Imaging System
(2018) Mater Foundation
Profiling of Immunoglobulin (Ig) G, IgM and IgA Isotype Immune Responses and Development of Autoantibody Biomarkers for Early Detection of Colorectal Cancer
Doctor Philosophy
Clinical applications of Immunoassays
Lawler, Karen and Kijanka, Gregor (2017). Clinical applications of Immunoassays. Immunoassays: development, applications and future trends. (pp. 161-190) edited by Richard O'Kennedy and Caroline Murphy. Singapore, Singapore: Pan Stanford Publishing.
Clinical applications of immunoassays
Lawler, Karen and Kijanka, Gregor (2017). Clinical applications of immunoassays. Immunoassays: development, applications and future trends. (pp. 161-190) edited by Richard O’Kennedy and Caroline Murphy. Boca Raton, FL, United States: Pan Stanford. doi: 10.1201/9781315206547-7
Mycofluidics: minaturization of mycotoxin analysis
Loftus JH, Kijanka G and O'Kennedy R (2017). Mycofluidics: minaturization of mycotoxin analysis. Diagnostic devices with microfluidics. (pp. 75-88) edited by Francesco Piraino, Šeila Selimović and Krzysztof Iniewski. Boca Raton, FL, United States: CRC Press (Taylor and Francis).
Kijanka, Gregor, Burger, Robert, Dimov, Ivan K., Padovani, Rima, Lawler, Karen, O'Kennedy, Richard and Ducrée, Jens (2011). Recent developments in cell-based microscale technologies and their potential application in personalised medicine. Advanced biomedical engineering. (pp. 93-104) edited by Gaetano D. Gargiulo and Alistair McEwan. Rijeka, Croatia: InTech . doi: 10.5772/23013
Sheng, Yong Hua, Giri, Rabina, Davies, Julie, Schreiber, Veronika, Alabbas, Saleh, Movva, Ramya, He, Yaowu, Wu, Andy, Hooper, John, McWhinney, Brett, Oancea, Iulia, Kijanka, Gregor, Hasnain, Sumaira, Lucke, Andrew J., Fairlie, David P., McGuckin, Michael A., Florin, Timothy H. and Begun, Jakob (2021). A nucleotide analog prevents colitis associated cancer via Β-catenin independently of inflammation and autophagy. Cellular and Molecular Gastroenterology and Hepatology, 11 (1), 33-53. doi: 10.1016/j.jcmgh.2020.05.012
Roney, Md Saiful Islam, Lanagan, Catharine, Sheng, Yong Hua, Lawler, Karen, Schmidt, Christopher, Nguyen, Nam‐Trung, Begun, Jakob and Kijanka, Gregor Stefan (2021). IgM and IgA augmented autoantibody signatures improve early‐stage detection of colorectal cancer prior to nodal and distant spread. Clinical and Translational Immunology, 10 (9) e1330, e1330. doi: 10.1002/cti2.1330
Microfluidic array chip for parallel detection of waterborne bacteria
Gorgannezhad, Lena, Sreejith, Kamalalayam, Zhang, Jun, Kijanka, Gregor, Christie, Melody, Stratton, Helen and Nguyen, Nam-Trung (2019). Microfluidic array chip for parallel detection of waterborne bacteria. Micromachines, 10 (12) 883, 883. doi: 10.3390/mi10120883
Brown, Peter, Tan, Aik-Choon, El-Esawi, Mohamed A., Liehr, Thomas, Blanck, Oliver, Gladue, Douglas P., Almeida, Gabriel M. F., Cernava, Tomislav, Sorzano, Carlos O., Yeung, Andy W. K., Engel, Michael S., Chandrasekaran, Arun Richard, Muth, Thilo, Staege, Martin S., Daulatabad, Swapna V., Widera, Darius, Zhang, Junpeng, Meule, Adrian, Honjo, Ken, Pourret, Olivier, Yin, Cong-Cong, Zhang, Zhongheng, Cascella, Marco, Flegel, Willy A., Goodyear, Carl S., van Raaij, Mark J., Bukowy-Bieryllo, Zuzanna, Campana, Luca G., Kurniawan, Nicholas A. ... RELISH Consortium (2019). Large expert-curated database for benchmarking document similarity detection in biomedical literature search. Database-The Journal of Biological Databases and Curation, 2019, 1-67. doi: 10.1093/database/baz085
MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity
Sheng, Yong Hua, Wong, Kuan Yau, Seim, Inge, Wang, Ran, He, Yaowu, Wu, Andy, Patrick, Maya, Lourie, Rohan, Schreiber, Veronika, Giri, Rabina, Ng, Choa Ping, Popat, Amirali, Hooper, John, Kijanka, Gregor, Florin, Timothy H., Begun, Jakob, Radford, Kristen J., Hasnain, Sumaira and McGuckin, Michael A. (2019). MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity. Oncogene, 38 (48), 7294-7310. doi: 10.1038/s41388-019-0951-y
Fitzgerald, Seán, O'Reilly, Julie-Ann, Wilson, Erin, Joyce, Ann, Farrell, Richard, Kenny, Dermot, Kay, Elaine Williamson, Fitzgerald, Jenny, Byrne, Barry, Kijanka, Gregor Stefan and O'Kennedy, Richard (2018). Measurement of the IgM and IgG autoantibody immune responses in human serum has high predictive value for the presence of colorectal cancer. Clinical Colorectal Cancer, 18 (1), e53-e60. doi: 10.1016/j.clcc.2018.09.009
Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment
Fitzgerald, Seán, Espina, Virginia, Liotta, Lance, Sheehan, Katherine M., O'Grady, Anthony, Cummins, Robert, O'Kennedy, Richard, Kay, Elaine W. and Kijanka, Gregor S. (2018). Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment. Journal of Translational Medicine, 16 (1) 89, 89. doi: 10.1186/s12967-018-1465-z
Loftus, Jonathan H., Kijanka, Gregor S., O’Kennedy, Richard and Loscher, Christine E. (2016). Patulin, deoxynivalenol, zearalenone and T-2 toxin affect viability and modulate cytokine secretion in J774A.1 murine macrophages. International Journal of Chemistry, 8 (2), 22-32. doi: 10.5539/ijc.v8n2p22
Referencing cross-reactivity of detection antibodies for protein array experiments
Lemass, Darragh, O'Kennedy, Richard and Kijanka, Gregor S. (2016). Referencing cross-reactivity of detection antibodies for protein array experiments. F1000Research, 5 73, 73.1-73.15. doi: 10.12688/f1000research.7668.2
Kijanka, Gregor S., Dimov, Ivan K., Burger, Robert and Ducrée, Jens (2015). Real-time monitoring of cell migration, phagocytosis and cell surface receptor dynamics using a novel, live-cell opto-microfluidic technique. Analytica Chimica Acta, 872, 95-99. doi: 10.1016/j.aca.2014.12.035
O'Reilly, Julie-Ann, Fitzgerald, Jenny, Fitzgerald, Sean, Kenny, Dermot, Kay, Elaine W., O'Kennedy, Richard and Kijanka, Gregor S. (2015). Diagnostic potential of zinc finger protein-specific autoantibodies and associated linear B-cell epitopes in colorectal cancer. PLoS One, 10 (4), e0123469.1-e0123469.13. doi: 10.1371/journal.pone.0123469
Kirby, Daniel, Glynn, Macdara, Kijanka, Gregor and Ducrée, Jens (2015). Rapid and cost-efficient enumeration of rare cancer cells from whole blood by low-loss centrifugo-magnetophoretic purification under stopped-flow conditions. Cytometry: Part A, 87 (1), 74-80. doi: 10.1002/cyto.a.22588
Burger, R., Kurzbuch, D., Gorkin, R., Kijanka, G., Glynn, M. and Ducrée, J. (2015). An integrated centrifugo-opto-microfluidic platform for arraying, analysis, identification and manipulation of individual cells. Lab On a Chip, 15 (2), 378-381. doi: 10.1039/c4lc01002g
Fitzgerald, Sean, Sheehan, Katherine M. , Espina, Virginia, O’Grady, Anthony, Cummins, Robert, Kenny, Dermot, Liotta, Lance, O’Kennedy, Richard, Kay, Elaine W. and Kijanka, Gregor S. (2015). High CerS5 expression levels associate with reduced patient survival and transition from apoptotic to autophagy signalling pathways in colorectal cancer. The Journal of Pathology Clinical Research, 1 (1), 54-65. doi: 10.1002/cjp2.5
Glynn, Macdara, Kirby, Daniel, Chung, Danielle, Kinahan, David J., Kijanka, Gregor and Ducree, Jens (2014). Centrifugo-magnetophoretic purification of CD4+ cells from whole blood toward future HIV/AIDS point-of-care applications. Journal of Laboratory Automation, 19 (3), 285-296. doi: 10.1177/2211068213504759
Fitzgerald, Sean, Sheehan, Katherine M., O'Grady, Anthony, Kenny, Dermot, O'Kennedy, Richard, Kay, Elaine W. and Kijanka, Gregor S. (2013). Relationship between epithelial and stromal TRIM28 expression predicts survival in colorectal cancer patients. Journal of Gastroenterology and Hepatology, 28 (6), 967-974. doi: 10.1111/jgh.12157
Centrifugo-magnetophoretic particle separation
Kirby, Daniel, Siegrist, Jonathan, Kijanka, Gregor, Zavattoni, Laetita, Shiels, Orla, O'Leary, John, Burger, Robert and Ducrée, Jens (2012). Centrifugo-magnetophoretic particle separation. Microfluidics and Nanofluidics, 13 (6), 899-908. doi: 10.1007/s10404-012-1007-6
Centrifugal microfluidics for cell analysis
Burger, Robert, Kirby, Daniel, Glynn, Macdara, Nwankire, Charles, O'Sullivan, Mary, Siegrist, Jonathan, Kinahan, David, Aguirre, Gerson, Kijanka, Gregor, Gorkin III, Robert A. and Ducrée, Jens (2012). Centrifugal microfluidics for cell analysis. Current Opinion in Chemical Biology, 16 (3), 409-414. doi: 10.1016/j.cbpa.2012.06.002
Burger, Robert, Reith, Patrick, Kijanka, Gregor, Akujobi, Victor, Abgrall, Patrick and Ducree, Jens (2012). Array-based capture, distribution, counting and multiplexed assaying of beads on a centrifugal microfluidic platform. Lab on a Chip, 12 (7), 1289-1295. doi: 10.1039/c2lc21170j
A reverse-ELISA for the detection of TRIM28/KAP1 serum autoantibodies in colorectal cancer patients
Hector, Suzanne, Chen, Hong, Kijanka, Gregor, Murray, Frank and Prehn, Jochen H. M. (2012). A reverse-ELISA for the detection of TRIM28/KAP1 serum autoantibodies in colorectal cancer patients. Acta Oncologica, 51 (3), 394-396. doi: 10.3109/0284186X.2011.652742
Integrated microfluidic array plate (iMAP) for cellular and molecular analysis
Dimov, Ivan K., Kijanka, Gregor, Park, Younggeun, Ducrée, Jens, Kang, Taewook and Lee, Luke P. (2011). Integrated microfluidic array plate (iMAP) for cellular and molecular analysis. Lab on a Chip, 11 (6), 2701-2710. doi: 10.1039/c1lc20105k
Kijanka, Gregor, Burger, Robert, Dimov, Ivan K., Padovani, Rima, Lawler, Karen, O'Kennedy, Richard and Ducree, Jens (2011). Recent Developments in Cell-Based Microscale Technologies and Their Potential Application in Personalised Medicine. Advanced Biomedical Engineering-Book, 93-104.
Kijanka, G., Hector, S., Kay, E. W., Murray, F., Cummins, R., Murphy, D., MacCraith, B. D., Prehn, J. H. and Kenny, D. (2010). Human IgG antibody profiles differentiate between symptomatic patients with and without colorectal cancer. Gut, 59 (1), 69-78. doi: 10.1136/gut.2009.178574
Kijanka, Gregor, Barry, Richard, Chen, Hong, Gould, Edith, Seidlits, Stephanie K., Schmid, Jasmin, Morgan, Maria, Mason, David Y., Cordell, Jacqueline and Murphy, Derek (2009). Defining the molecular target of an antibody derived from nuclear extract of Jurkat cells using protein arrays. Analytical Biochemistry, 395 (2), 119-124. doi: 10.1016/j.ab.2009.08.039
Protein arrays as tools for serum autoantibody marker discovery in cancer.
Kijanka, Gregor and Murphy, Derek (2009). Protein arrays as tools for serum autoantibody marker discovery in cancer.. Journal of Proteomics, 72 (6), 936-944. doi: 10.1016/j.jprot.2009.02.006
Kijanka, Gregor, Ipcho Simon, Baars, Sabine, Chen, Hong, Hadley, Katie, Beveridge, Allan, Gould, Edith and Murphy, Derek (2009). Rapid characterization of binding specificity and cross-reactivity of antibodies using recombinant human protein arrays. Journal of Immunological Methods, 340 (2), 132-137. doi: 10.1016/j.jim.2008.10.008
Seeing better through a MIST: evaluation of monoclonal recombinant antibody fragments on microarrays
Angenendt, Philipp, Wilde, Jeannine, Kijanka, Gregor, Baars, Sabine, Cahill, Dolores J., Kreutzberger, Jurgen, Lehrach, Hans, Konthur, Zoltan and Glökler, Jorn (2004). Seeing better through a MIST: evaluation of monoclonal recombinant antibody fragments on microarrays. Analytical Chemistry, 76 (10), 2916-2921. doi: 10.1021/ac035357a
Fitzgerald, Sean, Espina, Virginia, Sheehan, Katherine M., Cummins, Robert, O'Grady, Anthony, Kenny, Dermot, O'Kennedy, Richard, Liotta, Lance, Kay, Elaine W. and Kijanka, Gregor (2015). Molecular characterization of epithelial and stromal crosstalk associated with TRIM28 expression levels in colorectal cancer. AACR Special Conference on Cellular Heterogeneity in the Tumor Microenvironment, San Diego Ca, Feb 26-Mar 01, 2014. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.CHTME14-B55
Fitzgerald, Sean, Sheehan, Katherine M., O'Grady, Anthony, Kenny, Dermot, O'Kennedy, Richard, Kay, Elaine W. and Kijanka, Gregor (2013). Increased ceramide synthase 5 expression is associated with lymphovascular invasion, metastasis and poor survival in colorectal cancer. AACR 104th Annual Meeting 2013, Washington, DC, United States, 6-10 April 2013. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2013-1159
The Tumour-specific Antigen TRIM28 is an Independent Prognostic Marker in Colorectal Cancer
Fitzgerald, S., Sheehan, K. M., O'Grady, A., Kenny, D., O'Kennedy, R., Kay, E. W. and Kijanka, G. (2012). The Tumour-specific Antigen TRIM28 is an Independent Prognostic Marker in Colorectal Cancer. 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Dublin Ireland, Nov 06-09, 2012. OXFORD: ELSEVIER SCI LTD. doi: 10.1016/S0959-8049(12)72347-X
Lawler, Karen, Kijanka, Gregor, O' Sullivan, Gerald, Long, Aideen and Kenny, Dermot (2012). Shear stress induces Rac1/Rab5 circular ruffling/endosomes at the apical surface of metastatic esophageal tumor cells enhancing spreading and motility responses. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2012-4301
MULTIPLEXING OF HIGHLY REPRODUCIBLE, BEAD-BASED IMMUNOASSAYS ON A CENTRIFUGAL MICROFLUIDIC PLATFORM
Burger, Robert, Reith, Patrick, Abgrall, Patrick, Kijanka, Gregor and Ducree, Jens (2011). MULTIPLEXING OF HIGHLY REPRODUCIBLE, BEAD-BASED IMMUNOASSAYS ON A CENTRIFUGAL MICROFLUIDIC PLATFORM. 24th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Cancun Mexico, Jan 23-27, 2011. NEW YORK: IEEE. doi: 10.1109/memsys.2011.5734639
LAB-IN-A-TRENCH PLATFORM FOR REAL-TIME MONITORING OF CELL SURFACE PROTEIN EXPRESSION
Dimov, Ivan K., Kijanka, Gregor and Ducree, Jens (2010). LAB-IN-A-TRENCH PLATFORM FOR REAL-TIME MONITORING OF CELL SURFACE PROTEIN EXPRESSION. 23rd IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2010), Hong Kong Peoples R China, Jan 24-28, 2010. NEW YORK: IEEE. doi: 10.1109/MEMSYS.2010.5442556
Minimizing Stress Exposure to Cells Using Novel Microfluidic Cell Capture Devices
Kijanka, G., Dimov, I. K., Burger, R. and Ducree, J. (2009). Minimizing Stress Exposure to Cells Using Novel Microfluidic Cell Capture Devices. World Congress on Medical Physics and Biomedical Engineering, Munich Germany, Sep 07-12, 2009. NEW YORK: SPRINGER.
Microfluidic multiplexed cellular and molecular analysis device and method
Dimov, I., Ducrée, J., Lee, L. and Kijanka, G. (2014). Microfluidic multiplexed cellular and molecular analysis device and method. US8906669.
Method of assessing colorectal cancer status in an individual
Kijanka, Gregor, Kenny, Dermot and Kay, Elaine (2013). Method of assessing colorectal cancer status in an individual. 0098-1133;US 08426140.
(2018) Mater Foundation
Purchase of Odyssey CLx Imaging System
(2018) Mater Foundation
Profiling of Immunoglobulin (Ig) G, IgM and IgA Isotype Immune Responses and Development of Autoantibody Biomarkers for Early Detection of Colorectal Cancer
Doctor Philosophy — Associate Advisor
Other advisors: