The University of Queensland

Breast cancer metastasis to gynaecological organs: a clinico‐pathological and molecular profiling study

Kutasovic, Jamie R., McCart Reed, Amy E., Males, Renique, Sim, Sarah, Saunus, Jodi M., Dalley, Andrew, McEvoy, Christopher R., Dedina, Liana, Miller, Gregory, Peyton, Stephen, Reid, Lynne, Lal, Samir, Niland, Colleen, Ferguson, Kaltin, Fellowes, Andrew P., Al-Ejeh, Fares, Lakhani, Sunil R., Cummings, Margaret C. and Simpson, Peter T. (2019) Breast cancer metastasis to gynaecological organs: a clinico‐pathological and molecular profiling study. The Journal of Pathology: Clinical Research, 5 1: 25-39. doi:10.1002/cjp2.118

Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology

McCart Reed, Amy E., Kutasovic, Jamie R., Nones, Katia, Saunus, Jodi M., Da Silva, Leonard, Newell, Felicity, Kazakoff, Stephen, Melville, Lewis, Jayanthan, Janani, Vargas, Ana Cristina, Reid, Lynne E., Beesley, Jonathan, Chen, Xiao Qing, Patch, Anne Marie, David Clouston, D., Porter, Alan, Evans, Elizabeth, Pearson, John V., Chenevix-Trench, Georgia, Cummings, Margaret C., Waddell, Nic, Lakhani, Sunil R. and Simpson, Peter T. (2018) Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology. The Journal of Pathology, 244 4: 460-468. doi:10.1002/path.5040

LobSig is a multigene predictor of outcome in invasive lobular carcinoma

McCart Reed, Amy E., Lal, Samir, Kutasovic, Jamie R., Wockner, Leesa, Robertson, Alan, de Luca, Xavier M., Kalita-de Croft, Priyakshi, Dalley, Andrew J., Coorey, Craig P., Kuo, Luyu, Ferguson, Kaltin, Niland, Colleen, Miller, Gregory, Johnson, Julie, Reid, Lynne E., Males, Renique, Saunus, Jodi M., Chenevix-Trench, Georgia, Coin, Lachlan, Lakhani, Sunil R. and Simpson, Peter T. (2019) LobSig is a multigene predictor of outcome in invasive lobular carcinoma. npj Breast Cancer, 5 1: 18. doi:10.1038/s41523-019-0113-y

Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells

Genz, Berit, Coleman, Miranda A., Irvine, Katharine M., Kutasovic, Jamie R., Miranda, Mariska, Gratte, Francis D., Tirnitz-Parker, Janina E. E., Olynyk, John. K., Calvopina, Diego A., Weis, Anna, Cloonan, Nicole, Robinson, Harley, Hill, Michelle M., Al-Ejeh, Fares and Ramm, Grant A. (2019) Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells. Scientific Reports, 9 1: 8541. doi:10.1038/s41598-019-44865-1

Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer

Wiegmans, Adrian P., Saunus, Jodi M., Ham, Sunyoung, Lobb, Richard J., Kutasovic, Jamie R., Dalley, Andrew J., Miranda, Mariska, Atkinson, Caroline, Foliaki, Simote T., Ferguson, Kaltin, Niland, Colleen, Johnstone, Cameron N., Lewis, Victoria, Collins, Steven, Lakhani, Sunil R., Al-Ejeh, Fares and Möller, Andreas (2019) Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer. JCI Insight, . doi:10.1172/jci.insight.124092

Breast cancer metastasis to gynaecological organs: a clinico‐pathological and molecular profiling study

Kutasovic, Jamie R., McCart Reed, Amy E., Males, Renique, Sim, Sarah, Saunus, Jodi M., Dalley, Andrew, McEvoy, Christopher R., Dedina, Liana, Miller, Gregory, Peyton, Stephen, Reid, Lynne, Lal, Samir, Niland, Colleen, Ferguson, Kaltin, Fellowes, Andrew P., Al-Ejeh, Fares, Lakhani, Sunil R., Cummings, Margaret C. and Simpson, Peter T. (2019) Breast cancer metastasis to gynaecological organs: a clinico‐pathological and molecular profiling study. The Journal of Pathology: Clinical Research, 5 1: 25-39. doi:10.1002/cjp2.118

Recent advances in breast cancer research impacting clinical diagnostic practice : Breast cancer research - where are we now?

McCart Reed, Amy E, Kalita-de Croft, Priyakshi, Kutasovic, Jamie, Saunus, Jodi M and Lakhani, Sunil R (2018) Recent advances in breast cancer research impacting clinical diagnostic practice : Breast cancer research - where are we now?. The Journal of Pathology, . doi:10.1002/path.5199

Phenotypic and molecular dissection of Metaplastic Breast Cancer and the prognostic implications

McCart Reed, Amy Ellen, Kalaw, Emarene, Nones, Katia, Bettington, Mark, Lim, Malcolm, Bennett, James, Johnstone, Kate, Kutasovic, Jamie Rose, Saunus, Jodi Marie, Kazakoff, Stephen, Xu, Qinying, Wood, Scott, Holmes, Oliver, Leonard, Conrad, Reid, Lynne Estelle, Black, Debra, Niland, Colleen, Ferguson, Kaltin, Gresshoff, Irma, Raghavendra, Ashwini, Harvey, Kate, Cooper, Caroline, Liu, Cheng, Kalinowski, Lauren, Reid, Andrew Scott, Davidson, Morgan, Pearson, John V, Pathmanathan, Nirmala, Tse, Gary, Papadimos, David, Pathmanathan, Rajadurai, Harris, Gavin, Yamaguchi, Rin, Tan, Puay Hoon, Fox, Stephen, O'Toole, Sandra A., Simpson, Peter Thomas, Waddell, Nicola and Lakhani, Sunil R. (2018) Phenotypic and molecular dissection of Metaplastic Breast Cancer and the prognostic implications. Journal of Pathology, . doi:10.1002/path.5184

Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology

McCart Reed, Amy E., Kutasovic, Jamie R., Nones, Katia, Saunus, Jodi M., Da Silva, Leonard, Newell, Felicity, Kazakoff, Stephen, Melville, Lewis, Jayanthan, Janani, Vargas, Ana Cristina, Reid, Lynne E., Beesley, Jonathan, Chen, Xiao Qing, Patch, Anne Marie, David Clouston, D., Porter, Alan, Evans, Elizabeth, Pearson, John V., Chenevix-Trench, Georgia, Cummings, Margaret C., Waddell, Nic, Lakhani, Sunil R. and Simpson, Peter T. (2018) Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology. The Journal of Pathology, 244 4: 460-468. doi:10.1002/path.5040

Multidimensional phenotyping of breast cancer cell lines to guide preclinical research

Saunus, Jodi M., Smart, Chanel E., Kutasovic, Jamie R., Johnston, Rebecca L., Kalita-de Croft, Priyakshi, Miranda, Mariska, Rozali, Esdy N., Vargas, Ana Cristina, Reid, Lynne E., Lorsy, Eva, Cocciardi, Sibylle, Seidens, Tatjana, McCart Reed, Amy E., Dalley, Andrew J., Wockner, Leesa F., Johnson, Julie, Sarkar, Debina, Askarian-Amiri, Marjan E., Simpson, Peter T., Khanna, Kum Kum, Chenevix-Trench, Georgia, Al-Ejeh, Fares and Lakhani, Sunil R. (2017) Multidimensional phenotyping of breast cancer cell lines to guide preclinical research. Breast Cancer Research and Treatment, 167 1: 1-13. doi:10.1007/s10549-017-4496-x

Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer

Field, Sarah, Uyttenhove, Catherine, Stroobant, Vincent, Cheou, Paméla, Coutelier, Jean-Paul, Simpson, Peter T., Cummings, Margaret C., Saunus, Jodi M., Reid, Lynne E., Kutasovic, Jamie R., McNicol, Anne Marie, Kim, Ba Reun, Kim, Jae Ho, Lakhani, Sunil R., Neville, A. Munro, Van Snick, Jacques and Jat, Parmjit S. (2016) Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer. International Journal of Cancer, 138 8: 1959-1970. doi:10.1002/ijc.29946

An epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomas

McCart Reed, Amy E., Kutasovic, Jamie R., Vargas, Ana Cristina, Jayanthan, Janani, Al-Murrani, Amel, Reid, Lynne E., Chambers, Rachael, Da Silva, Leonard, Melville, Lewis, Evans, Elizabeth, Porter, Alan, Papadimos, David, Thompson, Erik W., Lakhani, Sunil R. and Simpson, Peter T. (2016) An epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomas. Journal of Pathology, 238 4: 489-494. doi:10.1002/path.4668

Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics

McCart Reed, Amy E., Kutasovic, Jamie R., Lakhani, Sunil R. and Simpson, Peter T. (2015) Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics. Breast Cancer Research, 17 12: 1-11. doi:10.1186/s13058-015-0519-x

Erratum: Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer

Al-Ejeh, F, Simpson, P T, Saunus, J M, Klein, K, Kalimutho, M, Shi, W, Miranda, M, Kutasovic, J, Raghavendra, A, Madore, J, Reid, L, Krause, L, Chenevix-Trench, G, Lakhani, S R and Khanna, K K (2014) Erratum: Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer. Oncogenesis, 3 10: e124-e124. doi:10.1038/oncsis.2014.41

Intratumour heterogeneity in the progression to breast cancer metastasis

Kutasovic, Jamie R., Sim, Sarah Y. M., McCart Reed, Amy E., Cummings, Margaret C. and Simpson, Peter T. (2014) Intratumour heterogeneity in the progression to breast cancer metastasis. Cancer Forum, 38 2: 138-142.

Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer

Al-Ejeh, F., Simpson, P. T., Sanus, J. M., Klein, K., Kalimutho, M., Shi, W., Miranda, M., Kutasovic, J., Raghavendra, A., Madore, J., Reid, L., Krause, L., Chenevix-Trench, G., Lakhani, S. R. and Khanna, K. K. (2014) Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer. Oncogenesis, 3 4: 1-12. doi:10.1038/oncsis.2014.14

Metastatic progression of breast cancer: Insights from 50 years of autopsies

Cummings, Margaret C., Simpson, Peter T., Reid, Lynne E., Jayanthan, Janani, Skerman, Joanna, Song, Sarah, McCart Reed, Amy E., Kutasovic, Jamie R., Morey, Adrienne L., Marquart, Louise, O'Rourke, Peter and Lakhani, Sunil R. (2014) Metastatic progression of breast cancer: Insights from 50 years of autopsies. Journal of Pathology, 232 1: 23-31. doi:10.1002/path.4288

Thrombospondin-4 expression is activated during the stromal response to invasive breast cancer

McCart Reed, Amy E., Song, Sarah, Kutasovic, Jamie R., Reid, Lynne E., Valle, Jordan M., Vargas, Ana Cristina, Smart, Chanel E. and Simpson, Peter T. (2013) Thrombospondin-4 expression is activated during the stromal response to invasive breast cancer. Virchows Archiv, 463 4: 535-545. doi:10.1007/s00428-013-1468-3

Evaluating the repair of DNA derived from formalin-fixed paraffin-embedded tissues prior to genomic profiling by SNP-CGH analysis

Hosein, Abdel Nasser, Song, Sarah, McCart Reed, Amy E., Jayanthan, Janani, Reid, Lynne E., Kutasovic, Jamie R., Cummings, Margaret C., Waddell, Nic, Lakhani, Sunil R., Chenevix-Trench, Georgia and Simpson, Peter T. (2013) Evaluating the repair of DNA derived from formalin-fixed paraffin-embedded tissues prior to genomic profiling by SNP-CGH analysis. Laboratory Investigation, 93 6: 701-710. doi:10.1038/labinvest.2013.54

Dissecting the heterogeneity of metaplastic breast cancer: a morphological, immunohistochemical and genomic analysis of a large cohort

Reed, A. E. McCart, Kalaw, E., Nones, K., Bettington, M., Lim, M., Bennett, J., Johnstone, K., Kutasovic, J. R., Kazakoff, S., Xu, Q. C., Saunus, J. M., Reid, L. E., Black, D., Niland, C., Ferguson, K., Gresshoff, I., Raghavendra, A., Liu, J. C., Kalinowski, L., Reid, A. S., Davidson, M., Pearson, J. V., Yamaguchi, R., Harris, G., Tse, G., Papadimos, D., Pathmanathan, R., Pathmanathan, N., Tan, P. H., Fox, S., O'Toole, S., Waddell, N., Simpson, P. T. and Lakhani, S. R. (2019). Dissecting the heterogeneity of metaplastic breast cancer: a morphological, immunohistochemical and genomic analysis of a large cohort. In: San Antonio Breast Cancer Symposium, San Antonio, TX, United States, (). 4-8 December 2018. doi:10.1158/1538-7445.SABCS18-P3-08-03

Expression of ARGLU and FBXL3 is highly prognostic for invasive lobular carcinoma

Coorey, Craig, Lal, Samir, Kutasovic, Jamie, Niland, Colleen, Ferguson, Kaltin, Kuo, Lu Yu, Reid, Lynne, Evans, Elizabeth, Porter, Alan, Lakhani, Sunil, McCart Reed, Amy and Simpson, Peter (2018). Expression of ARGLU and FBXL3 is highly prognostic for invasive lobular carcinoma. In: Unknown, Unknown, (S68). Unknown. doi:10.1016/j.pathol.2017.12.166

Immunohistochemical evaluation of FOXA1 expression and its correlation with breast cancer-specific survival: queensland follow up cohort

Dedina, Liana, Kutasovic, Jamie R., McCart Reed, Amy E., Simpson, Peter T. and Lakhani, Sunil R. (2017). Immunohistochemical evaluation of FOXA1 expression and its correlation with breast cancer-specific survival: queensland follow up cohort. In: Pathology Update Abstracts. Pathology Update 2017, Sydney Australia, (S70-S70). 24 - 26 February 2017. doi:10.1016/j.pathol.2016.12.174

Mixed ductal-lobular carcinomas of the breast: Abrogated cell adhesion in the clonal evolution from ductal to lobular morphology

Reed, A. E. McCart, Kutasovic, J. R., Nones, K., da Silva, L., Melville, L., Jayanthan, J., Vargas, A. C., Reid, L. E., Saunus, J. M., Cummings, M. M., Porter, A., Evans, E., Waddell, N., Lakhani, S. R. and Simpson, P. T. (2017). Mixed ductal-lobular carcinomas of the breast: Abrogated cell adhesion in the clonal evolution from ductal to lobular morphology. In: San Antonio Breast Cancer Symposium, San Antonio, TX, United States, (). 6-10 December 2016. doi:10.1158/1538-7445.SABCS16-P1-07-08

The development of personalized diagnostic tests and therapeutic strategies in breast cancer

Kutasovic, J. R., Rozali, E., Miranda, M., Lakhani, S. R. and Al-Ejeh, F. (2017). The development of personalized diagnostic tests and therapeutic strategies in breast cancer. In: San Antonio Breast Cancer Symposium, San Antonio, TX United States, (). 06-10 December 2016. doi:10.1158/1538-7445.SABCS16-P6-09-47

The development of personalized diagnostic tests and therapeutic strategies in breast cancer

Kutasovic, Jamie R., Rozali, Esdy, Miranda, Mariska, Lakhani, Sunil R. and Al-Ejeh, Fares (2016). The development of personalized diagnostic tests and therapeutic strategies in breast cancer. In: COSA's 43rd and ANZBCTG's 38th Annual Scientific Meetings. Partners for Progress in Breast Cancer Research and Care, Gold Coast, QLD Australia, (95-96). 15-17 November 2016.

Breast cancer metastasis to gynaecological organs: impacting young women diagnosed with a luminal tumour subtype

Kutasovic, Jamie, Reed, Amy McCart, Sim, Sarah, Cummings, Margaret, Lakhani, Sunil and Simpson, Peter (2015). Breast cancer metastasis to gynaecological organs: impacting young women diagnosed with a luminal tumour subtype. In: 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, (215-215). June 28th–July 1st, 2014. doi:10.1007/s10585-015-9708-3

The role of epithelial to mesenchymal plasticity in driving the invasive capacity of 'lobular-like' tumour cell differentiation in breast cancer

Reed, McCart A. E., Kutasovic, J. R., Vargas, A. C., Da Silva, L., Jayanthan, J., Al-Murrani, A., Reid, L. E., Evans, E., Porter, A., Lakhani, S. R. and Simpson, P. T. (2015). The role of epithelial to mesenchymal plasticity in driving the invasive capacity of 'lobular-like' tumour cell differentiation in breast cancer. In: 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, (239-240). June 28th–July 1st, 2014. doi:10.1007/s10585-015-9708-3

Abrogated cell-cell adhesion in the phenotypic drift from ductal to lobular breast cancer types

Da Silva, Leonard, McCart Reed, Amy E., Kutasovic, Jamie R., Vargas, Ana Cristina, Jayanthan, Janani, Reid, Lynne, Fritz, Brian, Cummings, Margaret C., Porter, Alan, Evans, Elizabeth, Lakhani, Sunil R. and Simpson, Peter T. (2012). Abrogated cell-cell adhesion in the phenotypic drift from ductal to lobular breast cancer types. In: 24th Lorne Cancer Conference 2012, Lorne, VIC, Australia, (). 9-11 February 2012.

Intratumour heterogeneity in the development and progression of breast cancer

Kutasovic, Jamie (2016). Intratumour heterogeneity in the development and progression of breast cancer PhD Thesis, School of Medicine, The University of Queensland. doi:10.14264/uql.2016.970