The University of Queensland

Improved concordance of challenging human epidermal growth factor receptor 2 dual in-situ hybridisation cases with the use of a digital image analysis algorithm in breast cancer

Gough, Madeline, Liu, Cheng, Srinivasan, Bhuvana, Wilkinson, Lisa, Dunk, Louisa, Yang, Yuanhao, Schreiber, Veronika, Tuffaha, Haitham, Kryza, Thomas, Hooper, John D., Lakhani, Sunil R. and Snell, Cameron E. (2023). Improved concordance of challenging human epidermal growth factor receptor 2 dual in-situ hybridisation cases with the use of a digital image analysis algorithm in breast cancer. Histopathology, 83 (4), 647-656. doi: 10.1111/his.15000

Inferring the genetic relationship between brain imaging-derived phenotypes and risk of complex diseases by Mendelian randomization and genome-wide colocalization

Lin, Siying, Zhang, Haoyang, Qi, Mengling, Cooper, David N., Yang, Yuedong, Yang, Yuanhao and Zhao, Huiying (2023). Inferring the genetic relationship between brain imaging-derived phenotypes and risk of complex diseases by Mendelian randomization and genome-wide colocalization. NeuroImage, 279 120325, 120325. doi: 10.1016/j.neuroimage.2023.120325

Novel plasma and brain proteins that are implicated in multiple sclerosis

Lin, Xin, Yang, Yuanhao, Gresle, Melissa, Cuellar-Partida, Gabriel, Han, Xikun, Stankovich, Jim, Fuh-Ngwa, Valery, Charlesworth, Jac, Burdon, Kathryn P, Butzkueven, Helmut, Taylor, Bruce V, Zhou, Yuan and AusLong/Ausimmune Investigators Group Steve Simpson-Yap (2023). Novel plasma and brain proteins that are implicated in multiple sclerosis. Brain, 146 (6) awac420, 2464-2475. doi: 10.1093/brain/awac420

Interactions between the lipidome and genetic and environmental factors in autism

Yap, Chloe X., Henders, Anjali K., Alvares, Gail A., Giles, Corey, Huynh, Kevin, Nguyen, Anh, Wallace, Leanne, McLaren, Tiana, Yang, Yuanhao, Hernandez, Leanna M., Gandal, Michael J., Hansell, Narelle K., Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren P., Leslie, Jodie, Levis Frenk, Mira, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Miller, Jessica L., Nunn, Lorelle, Strike, Lachlan T. ... The Busselton Health Study Investigators (2023). Interactions between the lipidome and genetic and environmental factors in autism. Nature Medicine, 29 (4), 936-949. doi: 10.1038/s41591-023-02271-1

Neural biomarker diagnosis and prediction to mild cognitive impairment and Alzheimer's disease using EEG technology

Jiao, Bin, Li, Rihui, Zhou, Hui, Qing, Kunqiang, Liu, Hui, Pan, Hefu, Lei, Yanqin, Fu, Wenjin, Wang, Xiaoan, Xiao, Xuewen, Liu, Xixi, Yang, Qijie, Liao, Xinxin, Zhou, Yafang, Fang, Liangjuan, Dong, Yanbin, Yang, Yuanhao, Jiang, Haiyan, Huang, Sha and Shen, Lu (2023). Neural biomarker diagnosis and prediction to mild cognitive impairment and Alzheimer's disease using EEG technology. Alzheimer's Research and Therapy, 15 (1) 32, 32. doi: 10.1186/s13195-023-01181-1

The shared genetic landscape of blood cell traits and risk of neurological and psychiatric disorders

Yang, Yuanhao, Zhou, Yuan, Nyholt, Dale R., Yap, Chloe X., Tannenberg, Rudolph K., Wang, Ying, Wu, Yang, Zhu, Zhihong, Taylor, Bruce V. and Gratten, Jacob (2023). The shared genetic landscape of blood cell traits and risk of neurological and psychiatric disorders. Cell Genomics, 3 (2) 100249, 100249. doi: 10.1016/j.xgen.2022.100249

Genetically determined serum serine level has a novel causal effect on multiple sclerosis risk and predicts disability progression

Lin, Xin, Yang, Yuanhao, Fuh-Ngwa, Valery, Yin, Xianyong, Simpson-Yap, Steve, van der Mei, Ingrid, Broadley, Simon A, Ponsonby, Anne-Louise, Burdon, Kathryn P, Taylor, Bruce V, Zhou, Yuan and Ausimmune/ AusLong Investigators Group (2023). Genetically determined serum serine level has a novel causal effect on multiple sclerosis risk and predicts disability progression. Journal of Neurology, Neurosurgery and Psychiatry, 94 (7) jnnp-2022-330259, 1-6. doi: 10.1136/jnnp-2022-330259

GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection

Foo, Cheng Xiang, Bartlett, Stacey, Chew, Keng Yih, Ngo, Minh Dao, Bielefeldt-Ohmann, Helle, Jayakody Arachchige, Buddhika, Matthews, Benjamin, Reed, Sarah, Wang, Ran, Smith, Christian, Sweet, Matthew J., Burr, Lucy, Bisht, Kavita, Shatunova, Svetlana, Sinclair, Jane E., Parry, Rhys, Yang, Yuanhao, Lévesque, Jean-Pierre, Khromykh, Alexander, Rosenkilde, Mette Marie, Short, Kirsty R. and Ronacher, Katharina (2023). GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection. European Respiratory Journal, 61 (3) 2201306, 1-15. doi: 10.1183/13993003.01306-2022

Sex differences of the shared genetic landscapes between type 2 diabetes and peripheral artery disease in East Asians and Europeans

Lu, Zhiya, Zhang, Haoyang, Yang, Yuanhao and Zhao, Huiying (2023). Sex differences of the shared genetic landscapes between type 2 diabetes and peripheral artery disease in East Asians and Europeans. Human Genetics, 142 (7), 965-980. doi: 10.1007/s00439-023-02573-x

Genetic evidence for a causal relationship between type 2 diabetes and peripheral artery disease in both Europeans and East Asians

Xiu, Xuehao, Zhang, Haoyang, Xue, Angli, Cooper, David N., Yan, Li, Yang, Yuedong, Yang, Yuanhao and Zhao, Huiying (2022). Genetic evidence for a causal relationship between type 2 diabetes and peripheral artery disease in both Europeans and East Asians. BMC Medicine, 20 (1) 300, 1-16. doi: 10.1186/s12916-022-02476-0

Integrating Genetic Structural Variations and Whole-Genome Sequencing Into Clinical Neurology

Lin, Xin, Yang, Yuanhao, Melton, Phillip E., Singh, Vikrant, Simpson-Yap, Steve, Burdon, Kathryn P., Taylor, Bruce V. and Zhou, Yuan (2022). Integrating Genetic Structural Variations and Whole-Genome Sequencing Into Clinical Neurology. Neurology: Genetics, 8 (4) e200005, 1-12. doi: 10.1212/NXG.0000000000200005

MUC1 mediated macrophage activation promotes colitis-associated colorectal cancer via activating the IL-6/STAT3 axis

Sheng, Yong H., Davies, Julie M., Wang, Ran, Wong, Kuan Yau, Giri, Rabina, Yang, Yuanhao, Begun, Jakob, Florin, Timothy H., Hasnain, Sumaira Z. and McGuckin, Michael A. (2022). MUC1 mediated macrophage activation promotes colitis-associated colorectal cancer via activating the IL-6/STAT3 axis. Cellular and Molecular Gastroenterology and Hepatology, 14 (4), 789-811. doi: 10.1016/j.jcmgh.2022.06.010

Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases

Yang, Yuanhao, Musco, Hannah, Simpson-Yap, Steve, Zhu, Zhihong, Wang, Ying, Lin, Xin, Zhang, Jiawei, Taylor, Bruce, Gratten, Jacob and Zhou, Yuan (2021). Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases. Nature Communications, 12 (1) 5641, 5641. doi: 10.1038/s41467-021-25768-0

Mendelian randomization study reveals a population-specific putative causal effect of type 2 diabetes in risk of cataract

Zhang, Haoyang, Xiu, Xuehao, Xue, Angli, Yang, Yuedong, Yang, Yuanhao and Zhao, Huiying (2021). Mendelian randomization study reveals a population-specific putative causal effect of type 2 diabetes in risk of cataract. International Journal of Epidemiology, 50 (6), 2024-2037. doi: 10.1093/ije/dyab175

Analysis of common genetic variation and rare CNVs in the Australian Autism Biobank

Yap, Chloe X., Alvares, Gail A., Henders, Anjali K., Lin, Tian, Wallace, Leanne, Farrelly, Alaina, McLaren, Tiana, Berry, Jolene, Vinkhuyzen, Anna A. E., Trzaskowski, Maciej, Zeng, Jian, Yang, Yuanhao, Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren, Leslie, Jodie, Levis Frenk, Mira, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Visscher, Peter M., Dawson, Paul A., Dissanayake, Cheryl ... Gratten, Jacob (2021). Analysis of common genetic variation and rare CNVs in the Australian Autism Biobank. Molecular Autism, 12 (1) 12, 12. doi: 10.1186/s13229-020-00407-5

Imprint of assortative mating on the human genome

Yengo, Loic, Robinson, Matthew R., Keller, Matthew C., Kemper, Kathryn E., Yang, Yuanhao, Trzaskowski, Maciej, Gratten, Jacob, Turley, Patrick, Cesarini, David, Benjamin, Daniel J., Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2018). Imprint of assortative mating on the human genome. Nature Human Behaviour, 2 (12), 948-954. doi: 10.1038/s41562-018-0476-3

Molecular genetic overlap between migraine and major depressive disorder

Yang, Yuanhao, Zhao, Huiying, Boomsma, Dorret I., Ligthart, Lannie, Belin, Andrea C., Smith, George Davey, Esko, Tonu, Freilinger, Tobias M., Hansen, Thomas Folkmann, Ikram, M. Arfan, Kallela, Mikko, Kubisch, Christian, Paraskevi, Christofidou, Strachan, David P., Wessman, Maija, International Headache Genetics Consortium, van den Maagdenberg, Arn M. J. M., Terwindt, Gisela M. and Nyholt, Dale R. (2018). Molecular genetic overlap between migraine and major depressive disorder. European Journal of Human Genetics, 26 (8), 1202-1216. doi: 10.1038/s41431-018-0150-2

Improving the detection of pathways in genome-wide association studies by combined effects of SNPs from Linkage Disequilibrium blocks

Zhao, Huiying, Nyholt, Dale R., Yang, Yuanhao, Wang, Jihua and Yang, Yuedong (2017). Improving the detection of pathways in genome-wide association studies by combined effects of SNPs from Linkage Disequilibrium blocks. Scientific Reports, 7 (1) 3512. doi: 10.1038/s41598-017-03826-2

A continuum of genetic liability for minor and major depression

Corfield, E. C., Yang, Y., Martin, N. G. and Nyholt, D. R. (2017). A continuum of genetic liability for minor and major depression. Translational Psychiatry, 7 (5) e1131, e1131-e1131. doi: 10.1038/tp.2017.99

Familial aggregation of migraine and depression: insights from a large Australian twin sample

Yang, Yuanhao, Zhao, Huiying, Heath, Andrew C., Madden, Pamela A. F., Martin, Nicholas G. and Nyholt, Dale R. (2016). Familial aggregation of migraine and depression: insights from a large Australian twin sample. Twin Research and Human Genetics, 19 (4), 312-321. doi: 10.1017/thg.2016.43

Shared genetic factors underlie migraine and depression

Yang, Yuanhao, Zhao, Huiying, Heath, Andrew C., Madden, Pamela A. F., Martin, Nicholas G. and Nyholt, Dale R. (2016). Shared genetic factors underlie migraine and depression. Twin Research and Human Genetics, 19 (4), 341-350. doi: 10.1017/thg.2016.46

Genetic epidemiology of migraine and depression

Yang, Yuanhao, Ligthart, Lannie, Terwindt, Gisela M., Boomsma, Dorret I., Rodriguez-Acevedo, Astrid J. and Nyholt, Dale R. (2016). Genetic epidemiology of migraine and depression. Cephalalgia, 36 (7), 679-691. doi: 10.1177/0333102416638520

HER2 in situ hybridization testing in breast cancer: applying algorithm-assisted assessment to reduce interobserver variability in difficult cases

Gough, Madeline, Liu, Cheng, Srinivasan, Bhuvana, Wilkinson, Lisa, Dunk, Louisa, Yang, Yuanhao, Tuffaha, Haitham, Kryza, Thomas, Hooper, John D., Lakhani, Sunil R. and Snell, Cameron Edward (2023). HER2 in situ hybridization testing in breast cancer: applying algorithm-assisted assessment to reduce interobserver variability in difficult cases. 2023 ASCO Annual Meeting, Chicago, IL United States, 2-6 June 2023. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2023.41.16_suppl.e13561

Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers

Gratten, Jacob, Yang, Yuanhao, Trzaskowski, Maciej, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Zhang, Futao, Zhu, Zhihong, Mcrae, Allan, Yang, Jian, Wray, Naomi and Visscher, Peter (2019). Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2018.08.167