Professor Chun-Xia Zhao is a Honorary Professor at the Australian Institute for Bioengineering and Nanotechnology (AIBN), University of Queensland. She is also a Professor at the School of Chemical Engineering and NHMRC Leadership Fellow at The University of Adelaide (UofA). Before joining UofA in 2021, Prof Zhao was a Group leader, UQ Amplify Fellow and an Australian Research Council (ARC) Future Fellow at AIBN, UQ. She was also the UQ Node Director and Leader of the Research Program 3 in ARC Centre of Excellence Eco-Efficient Beneficiation of Minerals.
Prof. Zhao joined Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland (UQ) in early 2008 as a Postdoctoral Fellow in Prof. Anton Middelberg's group, after obtained her PhD degree in Zhejiang University. In 2011, Prof. Zhao was awarded an ARC Discovery project along with the Australian Postdoctoral Fellow as the sole investigator. In 2014, she was awarded the prestigious Australian Research Council Future Fellow. Her research in bio-inspired nanotechnology and microfluidics has attracted more than $$50 M research funding in total since 2011, including six ARC grants as the Lead or Sole Investigator, three prestigious national Fellowships (Australian Postdoctoral Fellowship, ARC Future Fellowship and NHMRC Leadership Fellow), key CI in an ARC Centre of Excellence ($35M), CRC-P ($3 M), MRFF ($5M), as well as other university funding and industry funding. She worked with Prof. David Weitz at Harvard University as Fellow of the School of Engineering and Applied Science (2014). In 2016, her research excellence was recognised by the UQ Foundation Research Excellence Award. She has been appointed as member of the 2019 ARC College of Experts (2019-2021). She was awarded the NHMRC Leadership fellow in 2022.
Prof. Zhao has contributed substantial high quality scientific papers in international top refereed journals such as Nature Comm, PNAS, Science Advances, Angewandte Chemie International Edition, ACS Nano, etc. She has been focusing on innovative research, and has been active in patent application to transfer her research into practical applications, as evidenced by her six patents. One of her patents was licensed to an international company. She has built extensive collaborations with scientists at top universities such as Harvard University, Brown University, etc. She serves as the Editor-in-Chief, Editorial Board member for several journals.
Prof. Zhao has established a recognised international presence in the fields of nanomaterials, microfluidics and drug delivery. She has been invited to contribute three book chapters and many papers in top journals (e.g. Advanced Drug Delivery Review IF 15.5, ACS Nano IF=13.9, etc.). She has also been invited to present her work at international conferences (World Congress of Chemical Engineering, Annual World Congress of Advanced Materials, Annual World Congress of NanoMedicine, Bionano Innovation Conference, etc). Prof. Zhao is also an invited reviewer for more than 30 journals, including Nature Comm, Advanced Materials, Biomaterials, Chemical Communication, Lab on a Chip, etc.
Journal Article: Design of stimuli‐responsive peptides and proteins
Li, Yang, Yang, Guangze, Gerstweiler, Lukas, Thang, San H. and Zhao, Chun‐Xia (2023). Design of stimuli‐responsive peptides and proteins. Advanced Functional Materials, 33 (7) 2210387, 1-31. doi: 10.1002/adfm.202210387
Journal Article: Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions
Zou, Da, Wu, Zeming, Yi, Xin, Hui, Yue, Yang, Guangze, Liu, Yun, Tengjisi,, Wang, Haofei, Brooks, Anastasia, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S., Gao, Huajian and Zhao, Chun-Xia (2022). Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions. Proceedings of the National Academy of Sciences, 120 (1) e2214757120, e2214757120. doi: 10.1073/pnas.2214757120
Journal Article: Microfluidic nanoparticles for drug delivery
Liu, Yun, Yang, Guangze, Hui, Yue, Ranaweera, Supun and Zhao, Chun‐Xia (2022). Microfluidic nanoparticles for drug delivery. Small, 18 (36) 2106580, e2106580. doi: 10.1002/smll.202106580
Journal Article: J-aggregate-based FRET monitoring of drug release from polymer nanoparticles with high drug loading
Liu, Yun, Yang, Guangze, Jin, Song, Zhang, Run, Chen, Peng, Jisi, Teng, Wang, Lianzhou, Chen, Dong, Weitz, David and Zhao, Chun-Xia (2020). J-aggregate-based FRET monitoring of drug release from polymer nanoparticles with high drug loading. Angewandte Chemie, 132 (45) anie.202008018, 20240-20249. doi: 10.1002/anie.202008018
Journal Article: NIR-II bioluminescence for in vivo high contrast imaging and in situ ATP-mediated metastases tracing
Lu, Lingfei, Li, Benhao, Ding, Suwan, Fan, Yong, Wang, Shangfeng, Sun, Caixia, Zhao, Mengyao, Zhao, Chun-Xia and Zhang, Fan (2020). NIR-II bioluminescence for in vivo high contrast imaging and in situ ATP-mediated metastases tracing. Nature Communications, 11 (1) 4192, 4192. doi: 10.1038/s41467-020-18051-1
Journal Article: Active encapsulation in biocompatible nanocapsules
Wu, Baiheng, Yang, Chenjing, Li, Bo, Feng, Leyun, Hai, Mingtan, Zhao, Chun-Xia, Chen, Dong, Liu, Kai and Weitz, David A. (2020). Active encapsulation in biocompatible nanocapsules. Small, 16 (30) 2002716, 1-7. doi: 10.1002/smll.202002716
Journal Article: Nanoparticle elasticity regulates phagocytosis and cancer cell uptake
Hui, Yue, Yi, Xin, Wibowo, David, Yang, Guangze, Middelberg, Anton P. J., Gao, Huajian and Zhao, Chun-Xia (2020). Nanoparticle elasticity regulates phagocytosis and cancer cell uptake. Science Advances, 6 (16) eaaz4316, eaaz4316. doi: 10.1126/sciadv.aaz4316
Journal Article: Stable polymer nanoparticles with exceptionally high drug loading by sequential nanoprecipitation
Liu, Yun, Yang, Guangze, Baby, Thejus, Tengjisi, Chen, Dong, Weitz, David A. and Zhao, Chun-Xia (2020). Stable polymer nanoparticles with exceptionally high drug loading by sequential nanoprecipitation. Angewandte Chemie International Edition, 59 (12) ange.201913539, 4720-4728. doi: 10.1002/anie.201913539
Journal Article: Bioinspired core-shell nanoparticles for hydrophobic drug delivery
Yang, Guangze, Liu, Yun, Wang, Haofei, Wilson, Russell, Hui, Yue, Yu, Lei, Wibowo, David, Zhang, Cheng, Whittaker, Andrew K., Middelberg, Anton P. J. and Zhao, Chun-Xia (2019). Bioinspired core-shell nanoparticles for hydrophobic drug delivery. Angewandte Chemie (International Edition), 58 (40) ange.201908357, 14357-14364. doi: 10.1002/anie.201908357
Journal Article: Role of nanoparticle mechanical properties in cancer drug delivery
Hui, Yue, Yi, Xin, Hou, Fei, Wibowo, David, Zhang, Fan, Zhao, Dongyuan, Gao, Huajian and Zhao, Chun-Xia (2019). Role of nanoparticle mechanical properties in cancer drug delivery. ACS Nano, 13 (7) acsnano.9b03924, 7410-7424. doi: 10.1021/acsnano.9b03924
Journal Article: Controlled co-precipitation of biocompatible colorant-loaded nanoparticles by microfluidics for natural color drinks
Kong, Linlin, Chen, Ran, Wang, Xingzheng, Zhao, Chun-Xia, Chen, Qiushui, Hai, Mingtan, Chen, Dong, Yang, Zhenzhong and Weitz, David A. (2019). Controlled co-precipitation of biocompatible colorant-loaded nanoparticles by microfluidics for natural color drinks. Lab on a Chip, 19 (12), 2089-2095. doi: 10.1039/c9lc00240e
Journal Article: A microfluidic tumor-on-a-chip for assessing multifunctional liposomes' tumor targeting and anticancer efficacy
Ran, Rui, Wang, Hao-Fei, Hou, Fei, Liu, Yun, Hui, Yue, Petrovsky, Nikolai, Zhang, Fan and Zhao, Chun-Xia (2019). A microfluidic tumor-on-a-chip for assessing multifunctional liposomes' tumor targeting and anticancer efficacy. Advanced Healthcare Materials, 8 (8) 1900015, e1900015. doi: 10.1002/adhm.201900015
Journal Article: Tumor-vasculature-on-a-chip for investigating nanoparticle extravasation and tumor accumulation
Wang, Hao-Fei, Ran, Rui, Liu, Yun, Hui, Yue, Zeng, Bijun, Chen, Dong, Weitz, David A. and Zhao, Chun-Xia (2018). Tumor-vasculature-on-a-chip for investigating nanoparticle extravasation and tumor accumulation. ACS Nano, 12 (11) acsnano.8b06846, 11600-11609. doi: 10.1021/acsnano.8b06846
Journal Article: Microfluidic formation of coculture tumor spheroids with stromal cells as a novel 3D tumor model for drug testing
Sun, Qi, Tan, Say Hwa, Chen, Qiushui, Ran, Rui, Hui, Yue, Chen, Dong and Zhao, Chun-Xia (2018). Microfluidic formation of coculture tumor spheroids with stromal cells as a novel 3D tumor model for drug testing. ACS Biomaterials Science & Engineering, 4 (12) acsbiomaterials.8b00904, 4425-4433. doi: 10.1021/acsbiomaterials.8b00904
Journal Article: Microfluidic self-assembly of a combinatorial library of single- and dual-ligand liposomes for in vitro and in vivo tumor targeting
Ran, Rui, Wang, Haofei, Liu, Yun, Hui, Yue, Sun, Qi, Seth, Arjun, Wibowo, David, Chen, Dong and Zhao, Chun-Xia (2018). Microfluidic self-assembly of a combinatorial library of single- and dual-ligand liposomes for in vitro and in vivo tumor targeting. European Journal of Pharmaceutics and Biopharmaceutics, 130, 1-10. doi: 10.1016/j.ejpb.2018.06.017
Journal Article: Synergetic combinations of dual-targeting ligands for enhanced in vitro and in vivo tumor targeting
Liu, Yun, Hui, Yue, Ran, Rui, Yang, Guang-Ze, Wibowo, David, Wang, Hao-Fei, Middelberg, Anton P. J. and Zhao, Chun-Xia (2018). Synergetic combinations of dual-targeting ligands for enhanced in vitro and in vivo tumor targeting. Advanced Healthcare Materials, 7 (15) 1800106, e1800106. doi: 10.1002/adhm.201800106
Journal Article: Understanding the effects of nanocapsular mechanical property on passive and active tumor targeting
Hui, Yue, Wibowo, David, Liu, Yun, Ran, Rui, Wang, Hao-Fei, Seth, Arjun, Middelberg, Anton P. J. and Zhao, Chun-Xia (2018). Understanding the effects of nanocapsular mechanical property on passive and active tumor targeting. ACS Nano, 12 (3), 2846-2857. doi: 10.1021/acsnano.8b00242
Journal Article: Biocompatible amphiphilic hydrogel-solid dimer particles as colloidal surfactants
Chen, Dong, Amstad, Esther, Zhao, Chun-Xia, Cai, Liheng, Fan, Jing, Chen, Qiushui, Hai, Mingtan, Koehler, Stephan, Zhang, Huidan, Liang, Fuxin, Yang, Zhenzhong and Weitz, David A (2017). Biocompatible amphiphilic hydrogel-solid dimer particles as colloidal surfactants. ACS Nano, 11 (12), 11978-11985. doi: 10.1021/acsnano.7b03110
Journal Article: Interfacial engineering for silica nanocapsules
Wibowo, David, Hui, Yue, Middelberg, Anton P. J. and Zhao, Chun-Xia (2016). Interfacial engineering for silica nanocapsules. Advances in Colloid and Interface Science, 236, 83-100. doi: 10.1016/j.cis.2016.08.001
Journal Article: Emulsion-templated silica nanocapsules formed using bio-inspired silicification
Wibowo, David, Zhao, Chun-Xia and Middelberg, Anton P. J. (2014). Emulsion-templated silica nanocapsules formed using bio-inspired silicification. Chemical Communications, 50 (77), 11325-11328. doi: 10.1039/c4cc04904g
Journal Article: Multiphase flow microfluidics for the production of single or multiple emulsions for drug delivery
Zhao, Chun-Xia (2013). Multiphase flow microfluidics for the production of single or multiple emulsions for drug delivery. Advanced Drug Delivery Reviews, 65 (11-12), 1420-1446. doi: 10.1016/j.addr.2013.05.009
Journal Article: Microfluidic mass-transfer control for the simple formation of complex multiple emulsions
Zhao, Chun-Xia and Middelberg, Anton P. J. (2009). Microfluidic mass-transfer control for the simple formation of complex multiple emulsions. Angewandte Chemie-International Edition, 48 (39), 7208-7211. doi: 10.1002/anie.200902485
Mechanical modulation of particle-cell interactions
(2021) ARC Discovery Projects
Precision-engineered hybrid core-shell materials
(2020–2021) ARC Discovery Projects
Engineering encapsulation technology for animal feed manufacture
(2019–2023) Bioproton Pty Ltd
Bioinspired core-shell silica nanomaterials and their nano-bio interactions
(2022) Doctor Philosophy
Fundamental studies on extracellular matrix mimicking hydrogels for in vitro tumor models
(2022) Doctor Philosophy
Bioinspired Magnetic Nanomaterials for Drug Delivery
(2021) Doctor Philosophy
Precision engineering core-shell nanomaterials for drug delivery
Project 1
New platform technologies for making hybrid core-shell materials
Poor water solubility of many chemical actives hinders the development of new pharmaceutical, agricultural, food products. For example, 40% of approved drugs and 90% of drugs in development are water-insoluble. New methods are needed for more efficient formulation and delivery of these drugs. This project will develop new platform technologies for making hybrid core-shell materials with exceptionally high drug loading capacity and programmed drug release, delivering new technologies for the manufacture of high-value pharmaceutical product for various applications.
This project is supported by an ARC Discovery Project. Two PhD scholarships are available.
Project 2
Fast microfluidic screening platform for specific binding
Facile and quick platforms will be developed to screen biomolecule candidates for selective binding to specific metals. The screened biomolecules will be synthesized either using chemical synthesis methods or biological cell expression systems. The selective adsorption of the biomolecules on the target valuable metals will be systematically studied.
This project is supported by an ARC Centre of Excellence project. PhD scholarship is available.
Project 3
Development of stimuli responsive biomolecules for controlling different interfaces
Peptides or proteins are informational polymers made up of amino acids and are increasingly viewed as key building blocks to achieve specific functions owing to their biocompatibility, sustainability, and ease of functionalization, coupled with facile methods for their economic manufacture. Enabled by the diversity of the 20 naturally occurring amino acids, there is a large sequence and structural solution space for design. This project will explore the functionality of biomolecules to stabilise foams or emulsions, and the potential for switching that functionality based on different switching mechanisms.
This project is supported by an ARC Centre of Excellence project. PhD scholarship is available.
Please email z.chunxia@uq.edu.au with your CV, including a summary of academic qualifications, work and research experience, and publication list.
Design of stimuli‐responsive peptides and proteins
Li, Yang, Yang, Guangze, Gerstweiler, Lukas, Thang, San H. and Zhao, Chun‐Xia (2023). Design of stimuli‐responsive peptides and proteins. Advanced Functional Materials, 33 (7) 2210387, 1-31. doi: 10.1002/adfm.202210387
Zou, Da, Wu, Zeming, Yi, Xin, Hui, Yue, Yang, Guangze, Liu, Yun, Tengjisi,, Wang, Haofei, Brooks, Anastasia, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S., Gao, Huajian and Zhao, Chun-Xia (2022). Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions. Proceedings of the National Academy of Sciences, 120 (1) e2214757120, e2214757120. doi: 10.1073/pnas.2214757120
Microfluidic nanoparticles for drug delivery
Liu, Yun, Yang, Guangze, Hui, Yue, Ranaweera, Supun and Zhao, Chun‐Xia (2022). Microfluidic nanoparticles for drug delivery. Small, 18 (36) 2106580, e2106580. doi: 10.1002/smll.202106580
J-aggregate-based FRET monitoring of drug release from polymer nanoparticles with high drug loading
Liu, Yun, Yang, Guangze, Jin, Song, Zhang, Run, Chen, Peng, Jisi, Teng, Wang, Lianzhou, Chen, Dong, Weitz, David and Zhao, Chun-Xia (2020). J-aggregate-based FRET monitoring of drug release from polymer nanoparticles with high drug loading. Angewandte Chemie, 132 (45) anie.202008018, 20240-20249. doi: 10.1002/anie.202008018
NIR-II bioluminescence for in vivo high contrast imaging and in situ ATP-mediated metastases tracing
Lu, Lingfei, Li, Benhao, Ding, Suwan, Fan, Yong, Wang, Shangfeng, Sun, Caixia, Zhao, Mengyao, Zhao, Chun-Xia and Zhang, Fan (2020). NIR-II bioluminescence for in vivo high contrast imaging and in situ ATP-mediated metastases tracing. Nature Communications, 11 (1) 4192, 4192. doi: 10.1038/s41467-020-18051-1
Active encapsulation in biocompatible nanocapsules
Wu, Baiheng, Yang, Chenjing, Li, Bo, Feng, Leyun, Hai, Mingtan, Zhao, Chun-Xia, Chen, Dong, Liu, Kai and Weitz, David A. (2020). Active encapsulation in biocompatible nanocapsules. Small, 16 (30) 2002716, 1-7. doi: 10.1002/smll.202002716
Nanoparticle elasticity regulates phagocytosis and cancer cell uptake
Hui, Yue, Yi, Xin, Wibowo, David, Yang, Guangze, Middelberg, Anton P. J., Gao, Huajian and Zhao, Chun-Xia (2020). Nanoparticle elasticity regulates phagocytosis and cancer cell uptake. Science Advances, 6 (16) eaaz4316, eaaz4316. doi: 10.1126/sciadv.aaz4316
Stable polymer nanoparticles with exceptionally high drug loading by sequential nanoprecipitation
Liu, Yun, Yang, Guangze, Baby, Thejus, Tengjisi, Chen, Dong, Weitz, David A. and Zhao, Chun-Xia (2020). Stable polymer nanoparticles with exceptionally high drug loading by sequential nanoprecipitation. Angewandte Chemie International Edition, 59 (12) ange.201913539, 4720-4728. doi: 10.1002/anie.201913539
Bioinspired core-shell nanoparticles for hydrophobic drug delivery
Yang, Guangze, Liu, Yun, Wang, Haofei, Wilson, Russell, Hui, Yue, Yu, Lei, Wibowo, David, Zhang, Cheng, Whittaker, Andrew K., Middelberg, Anton P. J. and Zhao, Chun-Xia (2019). Bioinspired core-shell nanoparticles for hydrophobic drug delivery. Angewandte Chemie (International Edition), 58 (40) ange.201908357, 14357-14364. doi: 10.1002/anie.201908357
Role of nanoparticle mechanical properties in cancer drug delivery
Hui, Yue, Yi, Xin, Hou, Fei, Wibowo, David, Zhang, Fan, Zhao, Dongyuan, Gao, Huajian and Zhao, Chun-Xia (2019). Role of nanoparticle mechanical properties in cancer drug delivery. ACS Nano, 13 (7) acsnano.9b03924, 7410-7424. doi: 10.1021/acsnano.9b03924
Kong, Linlin, Chen, Ran, Wang, Xingzheng, Zhao, Chun-Xia, Chen, Qiushui, Hai, Mingtan, Chen, Dong, Yang, Zhenzhong and Weitz, David A. (2019). Controlled co-precipitation of biocompatible colorant-loaded nanoparticles by microfluidics for natural color drinks. Lab on a Chip, 19 (12), 2089-2095. doi: 10.1039/c9lc00240e
Ran, Rui, Wang, Hao-Fei, Hou, Fei, Liu, Yun, Hui, Yue, Petrovsky, Nikolai, Zhang, Fan and Zhao, Chun-Xia (2019). A microfluidic tumor-on-a-chip for assessing multifunctional liposomes' tumor targeting and anticancer efficacy. Advanced Healthcare Materials, 8 (8) 1900015, e1900015. doi: 10.1002/adhm.201900015
Tumor-vasculature-on-a-chip for investigating nanoparticle extravasation and tumor accumulation
Wang, Hao-Fei, Ran, Rui, Liu, Yun, Hui, Yue, Zeng, Bijun, Chen, Dong, Weitz, David A. and Zhao, Chun-Xia (2018). Tumor-vasculature-on-a-chip for investigating nanoparticle extravasation and tumor accumulation. ACS Nano, 12 (11) acsnano.8b06846, 11600-11609. doi: 10.1021/acsnano.8b06846
Sun, Qi, Tan, Say Hwa, Chen, Qiushui, Ran, Rui, Hui, Yue, Chen, Dong and Zhao, Chun-Xia (2018). Microfluidic formation of coculture tumor spheroids with stromal cells as a novel 3D tumor model for drug testing. ACS Biomaterials Science & Engineering, 4 (12) acsbiomaterials.8b00904, 4425-4433. doi: 10.1021/acsbiomaterials.8b00904
Ran, Rui, Wang, Haofei, Liu, Yun, Hui, Yue, Sun, Qi, Seth, Arjun, Wibowo, David, Chen, Dong and Zhao, Chun-Xia (2018). Microfluidic self-assembly of a combinatorial library of single- and dual-ligand liposomes for in vitro and in vivo tumor targeting. European Journal of Pharmaceutics and Biopharmaceutics, 130, 1-10. doi: 10.1016/j.ejpb.2018.06.017
Synergetic combinations of dual-targeting ligands for enhanced in vitro and in vivo tumor targeting
Liu, Yun, Hui, Yue, Ran, Rui, Yang, Guang-Ze, Wibowo, David, Wang, Hao-Fei, Middelberg, Anton P. J. and Zhao, Chun-Xia (2018). Synergetic combinations of dual-targeting ligands for enhanced in vitro and in vivo tumor targeting. Advanced Healthcare Materials, 7 (15) 1800106, e1800106. doi: 10.1002/adhm.201800106
Understanding the effects of nanocapsular mechanical property on passive and active tumor targeting
Hui, Yue, Wibowo, David, Liu, Yun, Ran, Rui, Wang, Hao-Fei, Seth, Arjun, Middelberg, Anton P. J. and Zhao, Chun-Xia (2018). Understanding the effects of nanocapsular mechanical property on passive and active tumor targeting. ACS Nano, 12 (3), 2846-2857. doi: 10.1021/acsnano.8b00242
Biocompatible amphiphilic hydrogel-solid dimer particles as colloidal surfactants
Chen, Dong, Amstad, Esther, Zhao, Chun-Xia, Cai, Liheng, Fan, Jing, Chen, Qiushui, Hai, Mingtan, Koehler, Stephan, Zhang, Huidan, Liang, Fuxin, Yang, Zhenzhong and Weitz, David A (2017). Biocompatible amphiphilic hydrogel-solid dimer particles as colloidal surfactants. ACS Nano, 11 (12), 11978-11985. doi: 10.1021/acsnano.7b03110
Interfacial engineering for silica nanocapsules
Wibowo, David, Hui, Yue, Middelberg, Anton P. J. and Zhao, Chun-Xia (2016). Interfacial engineering for silica nanocapsules. Advances in Colloid and Interface Science, 236, 83-100. doi: 10.1016/j.cis.2016.08.001
Emulsion-templated silica nanocapsules formed using bio-inspired silicification
Wibowo, David, Zhao, Chun-Xia and Middelberg, Anton P. J. (2014). Emulsion-templated silica nanocapsules formed using bio-inspired silicification. Chemical Communications, 50 (77), 11325-11328. doi: 10.1039/c4cc04904g
Multiphase flow microfluidics for the production of single or multiple emulsions for drug delivery
Zhao, Chun-Xia (2013). Multiphase flow microfluidics for the production of single or multiple emulsions for drug delivery. Advanced Drug Delivery Reviews, 65 (11-12), 1420-1446. doi: 10.1016/j.addr.2013.05.009
Microfluidic mass-transfer control for the simple formation of complex multiple emulsions
Zhao, Chun-Xia and Middelberg, Anton P. J. (2009). Microfluidic mass-transfer control for the simple formation of complex multiple emulsions. Angewandte Chemie-International Edition, 48 (39), 7208-7211. doi: 10.1002/anie.200902485
Colloidal Self-assembly of Block Copolymers for Drug Loading and Controlled Release
Yang, Guangze, Liuand, Yun and Zhao, Chun-Xia (2022). Colloidal Self-assembly of Block Copolymers for Drug Loading and Controlled Release. Functional Materials from Colloidal Self-assembly. (pp. 455-491) wiley. doi: 10.1002/9783527828722.ch13
Fluid properties and hydrodynamics of microfluidic systems
Wibowo, David, Zhao, Chun-Xia and He, Yinghe (2019). Fluid properties and hydrodynamics of microfluidic systems. Microfluidics for pharmaceutical applications. (pp. 37-77) Amsterdam, The Netherland: Elsevier. doi: 10.1016/b978-0-12-812659-2.00002-8
Synthesis and characterization of nanomaterials using microfluidic technology
Zhao, Chun-Xia and Middelberg, Anton P. J. (2016). Synthesis and characterization of nanomaterials using microfluidic technology. Handbook of nanoparticles. (pp. 455-473) edited by Mahmood Aliofkhazraei. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-15338-4_23
Stimuli-responsive peptide nanostructures at the fluid-fluid interface
Zhao, Chun-Xia and Middelberg, Anton P.J. (2013). Stimuli-responsive peptide nanostructures at the fluid-fluid interface. Protein nanotechnology: protocols, instrumentation, and applications. (pp. 179-194) edited by Juliet A. Gerrard. New York, NY United States: Humana Press. doi: 10.1007/978-1-62703-354-1_10
Luna‐Flores, Carlos H., Weng, Yilun, Wang, Alexander, Chen, Xiaojing, Peng, Bingyin, Zhao, Chun‐Xia, Navone, Laura, von Hellens, Juhani and Speight, Robert E. (2023). Improving phytase production in Pichia pastoris fermentations through de‐repression and methanol induction optimization. Biotechnology and Bioengineering, 120 (11), 3276-3287. doi: 10.1002/bit.28510
Real-Time Road Intersection Detection in Sparse Point Cloud Based on Augmented Viewpoints Beam Model
Hu, Di, Zhang, Kai, Yuan, Xia, Xu, Jiachen, Zhong, Yipan and Zhao, Chunxia (2023). Real-Time Road Intersection Detection in Sparse Point Cloud Based on Augmented Viewpoints Beam Model. Sensors, 23 (21), 8854. doi: 10.3390/s23218854
A biocompatible electrolyte enables highly reversible Zn anode for zinc ion battery
Li, Guanjie, Zhao, Zihan, Zhang, Shilin, Sun, Liang, Li, Mingnan, Yuwono, Jodie A., Mao, Jianfeng, Hao, Junnan, Vongsvivut, Jitraporn, Xing, Lidan, Zhao, Chun-Xia and Guo, Zaiping (2023). A biocompatible electrolyte enables highly reversible Zn anode for zinc ion battery. Nature Communications, 14 (1) 6526, 1-14. doi: 10.1038/s41467-023-42333-z
Ye, Chanqi, Yan, Xiaoxiao, Dai, Xiaomeng, Chen, Ruyin, Li, Qiong, Xu, Shuaishuai, Jiang, Qi, Yan, Feifei, Xu, Suzhen, Zhao, Chun-Xia, Zhao, Peng, Chen, Dong and Ruan, Jian (2023). Biocompatible snowman-like tumor-targeting dimer nanoparticles for improved delivery efficiency and enhanced anti-tumor therapy. Chemical Engineering Journal, 474 145766, 145766. doi: 10.1016/j.cej.2023.145766
Chen, Ruyin, Pu, Xingqun, Liu, Rongrong, Dai, Xiaomeng, Ye, Fangfu, Zhao, Chunxia, Zhao, Peng, Ruan, Jian and Chen, Dong (2023). Biocompatible Snowman-like Dimer Nanoparticles for Improved Cellular Uptake in Intrahepatic Cholangiocarcinoma. Pharmaceutics, 15 (8) 2132, 2132. doi: 10.3390/pharmaceutics15082132
Alginate-based materials for enzyme encapsulation
Weng, Yilun, Yang, Guangze, Li, Yang, Xu, Letao, Chen, Xiaojing, Song, Hao and Zhao, Chun-Xia (2023). Alginate-based materials for enzyme encapsulation. Advances in Colloid and Interface Science, 318 102957, 102957. doi: 10.1016/j.cis.2023.102957
Exploring Biosurfactants as a Sustainable Alternative to Chemical Surfactants
Li, Yang, Yang, Guangze, Weng, Yilun, Xu, Letao, Hou, Fei, Devkota, Shankar and Zhao, Chun-Xia (2023). Exploring Biosurfactants as a Sustainable Alternative to Chemical Surfactants. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 677 132291, 132291. doi: 10.1016/j.colsurfa.2023.132291
Xu, Letao, Wang, Xing, Yang, Guangze, Zhao, Zihan, Weng, Yilun, Li, Yang, Liu, Yun and Zhao, Chun‐Xia (2023). Development of a concentration‐controlled sequential nanoprecipitation for making lipid nanoparticles with high drug loading. Aggregate. doi: 10.1002/agt2.369
Impact of hydrogel biophysical properties on tumor spheroid growth and drug response
Cameron, Anna P., Gao, Song, Liu, Yun and Zhao, Chun-Xia (2023). Impact of hydrogel biophysical properties on tumor spheroid growth and drug response. Biomaterials Advances, 149 213421, 1-12. doi: 10.1016/j.bioadv.2023.213421
Weng, Yilun, Wan, Andria, Li, Yang, Liu, Yun, Chen, Xiaojing, Song, Hao and Zhao, Chun-Xia (2023). Scalable manufacturing of enzyme loaded alginate particles with excellent thermal and storage stability for industrial applications. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 667 131412, 1-10. doi: 10.1016/j.colsurfa.2023.131412
Selective feature fusion network for salient object detection
Sun, Fengming, Yuan, Xia and Zhao, Chunxia (2023). Selective feature fusion network for salient object detection. IET Computer Vision, 17 (4), 483-495. doi: 10.1049/cvi2.12183
Dai, Xiaomeng, Zhang, Jia, Bao, Xuanwen, Guo, Yixuan, Jin, Yuzhi, Yang, Chenjing, Zhang, Hangyu, Liu, Lulu, Gao, Yang, Ye, Chanqi, Wu, Wei, Liu, Chuan, Zhao, Chun‐Xia, Sheng, Jianpeng, Ren, En, Li, Hongjun, Fang, Weijia, Wu, Baiheng, Ruan, Jian, Gu, Zhen, Chen, Dong and Zhao, Peng (2023). Induction of Tumor Ferroptosis‐Dependent Immunity via an Injectable Attractive Pickering Emulsion Gel. Advanced Materials, 35 (35) 2303542. doi: 10.1002/adma.202303542
Divide-and-conquer model based on wavelet domain for multi-focus image fusion
Wu, Zhiliang, Zhang, Kang, Xuan, Hanyu, Yuan, Xia and Zhao, Chunxia (2023). Divide-and-conquer model based on wavelet domain for multi-focus image fusion. Signal Processing: Image Communication, 116 116982, 116982. doi: 10.1016/j.image.2023.116982
Improved enzyme thermal stability, loading and bioavailability using alginate encapsulation
Weng, Yilun, Ranaweera, Supun, Zou, Da, Cameron, Anna, Chen, Xiaojing, Song, Hao and Zhao, Chun-Xia (2023). Improved enzyme thermal stability, loading and bioavailability using alginate encapsulation. Food Hydrocolloids, 137 108385, 1-13. doi: 10.1016/j.foodhyd.2022.108385
Encapsulation of enzymes in food industry using spray drying: recent advances and process scale-ups
Weng, Yilun, Li, Yang, Chen, Xiaojing, Song, Hao and Zhao, Chun-Xia (2023). Encapsulation of enzymes in food industry using spray drying: recent advances and process scale-ups. Critical Reviews in Food Science and Nutrition, 1-18. doi: 10.1080/10408398.2023.2193982
Yang, Chenjing, Xiao, Yao, Hu, Lingjie, Chen, Jingyi, Zhao, Chun-Xia, Zhao, Peng, Ruan, Jian, Wu, Ziliang, Yu, Haifeng, Weitz, David A and Chen, Dong (2023). Stimuli-triggered multishape, multimode, and multistep deformations designed by microfluidic 3D droplet printing. Small, 19 (11) 2207073, 1-7. doi: 10.1002/smll.202207073
Rich‐scale feature fusion network for salient object detection
Sun, Fengming, Cui, Junjie, Yuan, Xia and Zhao, Chunxia (2023). Rich‐scale feature fusion network for salient object detection. IET Image Processing, 17 (3), 794-806. doi: 10.1049/ipr2.12673
Design of stimuli‐responsive peptides and proteins
Li, Yang, Yang, Guangze, Gerstweiler, Lukas, Thang, San H. and Zhao, Chun‐Xia (2023). Design of stimuli‐responsive peptides and proteins. Advanced Functional Materials, 33 (7) 2210387, 1-31. doi: 10.1002/adfm.202210387
Two-phase self-supervised pretraining for object re-identification
Ma, Haoyan, Li, Xiang, Yuan, Xia and Zhao, Chunxia (2023). Two-phase self-supervised pretraining for object re-identification. Knowledge-Based Systems, 261 110220, 1-12. doi: 10.1016/j.knosys.2022.110220
Phase separation‐induced nanoprecipitation for making polymer nanoparticles with high drug loading
Yang, Guangze, Liu, Yun, Jin, Song, Hui, Yue, Wang, Xing, Xu, Letao, Chen, Dong, Weitz, David and Zhao, Chun‐Xia (2023). Phase separation‐induced nanoprecipitation for making polymer nanoparticles with high drug loading. Aggregate, 4 (2) e314. doi: 10.1002/agt2.314
Zou, Da, Wu, Zeming, Yi, Xin, Hui, Yue, Yang, Guangze, Liu, Yun, Tengjisi,, Wang, Haofei, Brooks, Anastasia, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S., Gao, Huajian and Zhao, Chun-Xia (2022). Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions. Proceedings of the National Academy of Sciences, 120 (1) e2214757120, e2214757120. doi: 10.1073/pnas.2214757120
Axons-on-a-chip for mimicking non-disruptive diffuse axonal injury underlying traumatic brain injury
Pan, Xiaorong, Li, Jie, Li, Wei, Wang, Haofei, Durisic, Nela, Li, Zhenyu, Feng, Yu, Liu, Yifan, Zhao, Chun-Xia and Wang, Tong (2022). Axons-on-a-chip for mimicking non-disruptive diffuse axonal injury underlying traumatic brain injury. Lab on a Chip, 22 (23), 4541-4555. doi: 10.1039/d2lc00730d
Chen, Li, Xiao, Yao, Zhang, Zhiming, Zhao, Chun-Xia, Guo, Baoling, Ye, Fangfu and Chen, Dong (2022). Porous ultrathin-shell microcapsules designed by microfluidics for selective permeation and stimuli-triggered release. Frontiers of Chemical Science and Engineering, 16 (11), 1643-1650. doi: 10.1007/s11705-022-2201-z
Bioinspired core-shell silica nanoparticles monitoring extra- and intra-cellular drug release
Tengjisi, , Liu, Yun, Zou, Da, Yang, Guangze and Zhao, Chun-Xia (2022). Bioinspired core-shell silica nanoparticles monitoring extra- and intra-cellular drug release. Journal of Colloid and Interface Science, 624, 242-250. doi: 10.1016/j.jcis.2022.05.099
Li, Xuanhe, Zhao, Chun-Xia and Lin, Liangliang (2022). Plasma-based instant synthesis of functionalized gold nanoparticles for colorimetric detection of lead ions. Chemical Engineering Science, 260 117849. doi: 10.1016/j.ces.2022.117849
Alginate particles for enzyme immobilization using spray drying
Weng, Yilun, Ranaweera, Supun, Zou, Da, Cameron, Anna, Chen, Xiaojing, Song, Hao and Zhao, Chun-Xia (2022). Alginate particles for enzyme immobilization using spray drying. Journal of Agricultural and Food Chemistry, 70 (23), 7139-7147. doi: 10.1021/acs.jafc.2c02298
Biophysical properties of hydrogels for mimicking tumor extracellular matrix
Cameron, Anna P., Zeng, Bijun, Liu, Yun, Wang, Haofei, Soheilmoghaddam, Farhad, Cooper-White, Justin and Zhao, Chun-Xia (2022). Biophysical properties of hydrogels for mimicking tumor extracellular matrix. Biomaterials Advances, 136 212782, 212782. doi: 10.1016/j.bioadv.2022.212782
Microfluidic nanoparticles for drug delivery
Liu, Yun, Yang, Guangze, Hui, Yue, Ranaweera, Supun and Zhao, Chun‐Xia (2022). Microfluidic nanoparticles for drug delivery. Small, 18 (36) 2106580, e2106580. doi: 10.1002/smll.202106580
Morphology control of trimer particles via one-step co-precipitation and controlled phase separation
Chen, Li, Chen, Jinyi, Sun, Zhu, Wu, Baiheng, Ye, Fangfu, Zhao, Chun-Xia and Chen, Dong (2022). Morphology control of trimer particles via one-step co-precipitation and controlled phase separation. Chemical Engineering Science, 251 117432, 117432. doi: 10.1016/j.ces.2022.117432
Tian, Tian, Ruan, Jian, Zhang, Jia, Zhao, Chun-Xia, Chen, Dong and Shan, Jianzhen (2022). Nanocarrier-based tumor-targeting drug delivery systems for hepatocellular carcinoma treatments: enhanced therapeutic efficacy and reduced drug toxicity. Journal of Biomedical Nanotechnology, 18 (3), 660-676. doi: 10.1166/jbn.2022.3297
Orthogonal multiplexed NIR-II imaging with excitation-selective lanthanide-based nanoparticles
Xu, Houben, Yang, Yang, Lu, Lingfei, Yang, Yiwei, Zhang, Zhengcheng, Zhao, Chun-Xia, Zhang, Fan and Fan, Yong (2022). Orthogonal multiplexed NIR-II imaging with excitation-selective lanthanide-based nanoparticles. Analytical Chemistry, 94 (8) acs.analchem.1c05253, 3661-3668. doi: 10.1021/acs.analchem.1c05253
Influence of nanoparticle mechanical property on protein corona formation
Tengjisi, Hui, Yue, Fan, Yuanyuan, Zou, Da, Talbo, Gert H., Yang, Guangze and Zhao, Chun-Xia (2022). Influence of nanoparticle mechanical property on protein corona formation. Journal of Colloid and Interface Science, 606 (Pt 2), 1737-1744. doi: 10.1016/j.jcis.2021.08.148
Liu, Jiaqi, Yang, Zhen, Che, Yuanyuan, Zhang, Yaojie, Zhang, Zhihao and Zhao, Chun-Xia (2022). Computational investigation of metal organic frameworks as potential drug carriers for antihypertensive amlodipine. AIChE Journal, 68 (1) e17474. doi: 10.1002/aic.17474
FRET ratiometric nanoprobes for nanoparticle monitoring
Yang, Guangze, Liu, Yun, Teng, Jisi and Zhao, Chun-Xia (2021). FRET ratiometric nanoprobes for nanoparticle monitoring. Biosensors, 11 (12) 505. doi: 10.3390/bios11120505
Lipid nanoparticles for drug delivery
Xu, Letao, Wang, Xing, Liu, Yun, Yang, Guangze, Falconer, Robert J. and Zhao, Chun-Xia (2021). Lipid nanoparticles for drug delivery. Advanced NanoBiomed Research, 2 (2) 2100109, 2100109. doi: 10.1002/anbr.202100109
Facile bioinspired synthesis of iron oxide encapsulating silica nanocapsules
Wilson, Russell J., Hui, Yue, Whittaker, Andrew K. and Zhao, Chun-Xia (2021). Facile bioinspired synthesis of iron oxide encapsulating silica nanocapsules. Journal of Colloid and Interface Science, 601, 78-84. doi: 10.1016/j.jcis.2021.05.021
Dai, Xiaomeng, Ruan, Jian, Guo, Yixuan, Sun, Zhu, Liu, Junqing, Bao, Xuanwen, Zhang, Hangyu, Li, Qiong, Ye, Chanqi, Wang, Xun, Zhao, Chun-Xia, Zhou, Feng, Sheng, Jianpeng, Chen, Dong and Zhao, Peng (2021). Enhanced radiotherapy efficacy and induced anti-tumor immunity in HCC by improving hypoxia microenvironment using oxygen microcapsules. Chemical Engineering Journal, 422 130109, 130109. doi: 10.1016/j.cej.2021.130109
Quantitative comparison of different fluorescent dye-loaded nanoparticles
Yang, Guangze, Liu, Yun and Zhao, Chun-Xia (2021). Quantitative comparison of different fluorescent dye-loaded nanoparticles. Colloids and Surfaces B: Biointerfaces, 206 111923, 111923. doi: 10.1016/j.colsurfb.2021.111923
Baby, Thejus, Liu, Yun, Yang, Guangze, Chen, Dong and Zhao, Chun-Xia (2021). Microfluidic synthesis of curcumin loaded polymer nanoparticles with tunable drug loading and pH-triggered release. Journal of Colloid and Interface Science, 594, 474-484. doi: 10.1016/j.jcis.2021.03.035
Yang, Guangze, Liu, Yun, Hui, Yue, Tengjisi, Chen, Dong, Weitz, David A. and Zhao, Chun-Xia (2021). Implications of quenching‐to-dequenching switch in quantitative cell uptake and biodistribution of dye‐labeled nanoparticles. Angewandte Chemie, 133 (28) ange.202101730, 15554-15563. doi: 10.1002/ange.202101730
Liver organoid as a 3D in vitro model for drug validation and toxicity assessment
Brooks, Anastasia, Liang, Xiaowen, Zhang, Yonglong, Zhao, Chun-Xia, Roberts, Michael S., Wang, Haolu, Zhang, Lei and Crawford, Darrell H.G. (2021). Liver organoid as a 3D in vitro model for drug validation and toxicity assessment. Pharmacological Research, 169 105608, 105608. doi: 10.1016/j.phrs.2021.105608
Templating core-shell particles using metal ion-chelating biosurfactants
Yeh, Ching-Min, Jarrett, Thomas, Gao, Yuan, Zhao, Chun-Xia, Whittaker, Andrew, Sainsbury, Frank and White, Alison L. (2021). Templating core-shell particles using metal ion-chelating biosurfactants. Particuology, 64, 145-152. doi: 10.1016/j.partic.2021.06.003
Artificial cells for the treatment of liver diseases
Zou, Da, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S. and Zhao, Chun-Xia (2021). Artificial cells for the treatment of liver diseases. Acta Biomaterialia, 130, 98-114. doi: 10.1016/j.actbio.2021.06.012
Nanoemulsions for drug delivery
Wilson, Russell J., Li, Yang, Yang, Guangze and Zhao, Chun-Xia (2021). Nanoemulsions for drug delivery. Particuology, 64, 85-97. doi: 10.1016/j.partic.2021.05.009
Insight into drug encapsulation in polymeric nanoparticles using microfluidic nanoprecipitation
Li, Wei, Chen, Qiaoli, Baby, Thejus, Jin, Song, Liu, Yun, Yang, Guangze and Zhao, Chun-Xia (2021). Insight into drug encapsulation in polymeric nanoparticles using microfluidic nanoprecipitation. Chemical Engineering Science, 235 116468, 116468. doi: 10.1016/j.ces.2021.116468
Yang, Guangze, Liu, Yun, Hui, Yue, Tengjisi, , Chen, Dong, Weitz, David A. and Zhao, Chun‐Xia (2021). Implications of Quenching-to-Dequenching Switch in Quantitative Cell Uptake and Biodistribution of Dye-Labeled Nanoparticles. Angewandte Chemie, 133 (28) ange.202105984, 15242-15242. doi: 10.1002/ange.202105984
Yang, Guangze, Liu, Yun, Hui, Yue, Tengjisi, , Chen, Dong, Weitz, David A. and Zhao, Chun‐Xia (2021). Inside Cover: Implications of Quenching‐to‐Dequenching Switch in Quantitative Cell Uptake and Biodistribution of Dye‐Labeled Nanoparticles (Angew. Chem. Int. Ed. 28/2021). Angewandte Chemie International Edition, 60 (28), 15114-15114. doi: 10.1002/anie.202105984
Droplet shape control using microfluidics and designer biosurfactants
Gao, Yuan, Zhao, Chun-Xia and Sainsbury, Frank (2021). Droplet shape control using microfluidics and designer biosurfactants. Journal of Colloid and Interface Science, 584, 528-538. doi: 10.1016/j.jcis.2020.09.126
Wu, Baiheng, Sun, Zhu, Wu, Jiangchao, Ruan, Jian, Zhao, Peng, Liu, Kai, Zhao, Chun-Xia, Sheng, Jianpeng, Liang, Tingbo and Chen, Dong (2021). Nanoparticle-stabilized oxygen microcapsules prepared by interfacial polymerization for enhanced oxygen delivery. Angewandte Chemie (International Edition), 60 (17), 9284-9289. doi: 10.1002/anie.202100752
Antifouling surfaces enabled by surface grafting of highly hydrophilic sulfoxide polymer brushes
Xu, Xin, Huang, Xumin, Chang, Yixin, Yu, Ye, Zhao, Jiacheng, Isahak, Naatasha, Teng, Jisi, Qiao, Ruirui, Peng, Hui, Zhao, Chun-Xia, Davis, Thomas P., Fu, Changkui and Whittaker, Andrew K. (2021). Antifouling surfaces enabled by surface grafting of highly hydrophilic sulfoxide polymer brushes. Biomacromolecules, 22 (2), 330-339. doi: 10.1021/acs.biomac.0c01193
Sun, Zhu, Wu, Baiheng, Ren, Yixin, Wang, Zhongzhen, Zhao, Chun-Xia, Hai, Mingtan, Weitz, David A. and Chen, Dong (2021). Diverse particle carriers prepared by co‐precipitation and phase separation: formation and applications. ChemPlusChem, 86 (1) cplu.202000497, 49-58. doi: 10.1002/cplu.202000497
Integration of microfluidic systems with external fields for multiphase process intensification
Yang, Mei, Gao, Yuan, Liu, Yun, Yang, Guangze, Zhao, Chun-Xia and Wu, Ke-Jun (2021). Integration of microfluidic systems with external fields for multiphase process intensification. Chemical Engineering Science, 234 116450, 116450. doi: 10.1016/j.ces.2021.116450
J-aggregate-based FRET monitoring of drug release from polymer nanoparticles with high drug loading
Liu, Yun, Yang, Guangze, Jin, Song, Zhang, Run, Chen, Peng, Jisi, Teng, Wang, Lianzhou, Chen, Dong, Weitz, David and Zhao, Chun-Xia (2020). J-aggregate-based FRET monitoring of drug release from polymer nanoparticles with high drug loading. Angewandte Chemie, 132 (45) anie.202008018, 20240-20249. doi: 10.1002/anie.202008018
Macrophage-mediated cancer drug delivery
Wang, Hao-Fei, Liu, Yun, Yang, Guangze and Zhao, Chun-Xia (2020). Macrophage-mediated cancer drug delivery. Materials Today Sustainability, 11-12 100055, 100055. doi: 10.1016/j.mtsust.2020.100055
A general approach for biomimetic mineralization of MOF particles using biomolecules
Zou, Da, Yu, Lei, Sun, Qi, Hui, Yue, Tengjisi,, Liu, Yun, Yang, Guangze, Wibowo, David and Zhao, Chun-Xia (2020). A general approach for biomimetic mineralization of MOF particles using biomolecules. Colloids and Surfaces B: Biointerfaces, 193 111108, 111108. doi: 10.1016/j.colsurfb.2020.111108
Development of high‐drug‐loading nanoparticles
Liu, Yun, Yang, Guangze, Jin, Song, Xu, Letao and Zhao, Chun-Xia (2020). Development of high‐drug‐loading nanoparticles. ChemPlusChem, 85 (9) cplu.202000496, 2143-2157. doi: 10.1002/cplu.202000496
NIR-II bioluminescence for in vivo high contrast imaging and in situ ATP-mediated metastases tracing
Lu, Lingfei, Li, Benhao, Ding, Suwan, Fan, Yong, Wang, Shangfeng, Sun, Caixia, Zhao, Mengyao, Zhao, Chun-Xia and Zhang, Fan (2020). NIR-II bioluminescence for in vivo high contrast imaging and in situ ATP-mediated metastases tracing. Nature Communications, 11 (1) 4192, 4192. doi: 10.1038/s41467-020-18051-1
Tumor-microenvironment-on-a-chip for evaluating nanoparticle-loaded macrophages for drug delivery
Wang, Hao-Fei, Liu, Yun, Wang, Tong, Yang, Guangze, Zeng, Bijun and Zhao, Chun-Xia (2020). Tumor-microenvironment-on-a-chip for evaluating nanoparticle-loaded macrophages for drug delivery. ACS Biomaterials Science and Engineering, 6 (9) acsbiomaterials.0c00650, 5040-5050. doi: 10.1021/acsbiomaterials.0c00650
Biomimetic core-shell silica nanoparticles using a dual-functional peptide
Tengjisi, Hui, Yue, Yang, Guangze, Fu, Changkui, Liu, Yun and Zhao, Chun-Xia (2020). Biomimetic core-shell silica nanoparticles using a dual-functional peptide. Journal of Colloid and Interface Science, 581 (Pt A), 185-194. doi: 10.1016/j.jcis.2020.07.107
Active encapsulation in biocompatible nanocapsules
Wu, Baiheng, Yang, Chenjing, Li, Bo, Feng, Leyun, Hai, Mingtan, Zhao, Chun-Xia, Chen, Dong, Liu, Kai and Weitz, David A. (2020). Active encapsulation in biocompatible nanocapsules. Small, 16 (30) 2002716, 1-7. doi: 10.1002/smll.202002716
Development of core‐shell nanoparticle drug delivery systems based on biomimetic mineralization
Yang, Guangze, Liu, Yun, Jin, Song and Zhao, Chun‐Xia (2020). Development of core‐shell nanoparticle drug delivery systems based on biomimetic mineralization. ChemBioChem, 21 (20) cbic.202000105, 2871-2879. doi: 10.1002/cbic.202000105
Sustained-release ketamine-loaded nanoparticles fabricated by sequential nanoprecipitation
Han, Felicity Y., Liu, Yun, Kumar, Vinod, Xu, Weizhi, Yang, Guangze, Zhao, Chun-Xia, Woodruff, Trent M., Whittaker, Andrew K. and Smith, Maree T. (2020). Sustained-release ketamine-loaded nanoparticles fabricated by sequential nanoprecipitation. International Journal of Pharmaceutics, 581 119291, 119291. doi: 10.1016/j.ijpharm.2020.119291
Development of a microfluidic droplet-based microbioreactor for microbial cultivation
Ho, Chee Meng Benjamin, Sun, Qi, Teo, Adrian J. T., Wibowo, David, Gao, Yongsheng, Zhou, Jun, Huang, Yanyi, Tan, Say Hwa and Zhao, Chun-Xia (2020). Development of a microfluidic droplet-based microbioreactor for microbial cultivation. ACS Biomaterials Science and Engineering, 6 (6) acsbiomaterials.0c00292, 3630-3637. doi: 10.1021/acsbiomaterials.0c00292
Nanoparticle elasticity regulates phagocytosis and cancer cell uptake
Hui, Yue, Yi, Xin, Wibowo, David, Yang, Guangze, Middelberg, Anton P. J., Gao, Huajian and Zhao, Chun-Xia (2020). Nanoparticle elasticity regulates phagocytosis and cancer cell uptake. Science Advances, 6 (16) eaaz4316, eaaz4316. doi: 10.1126/sciadv.aaz4316
Stable polymer nanoparticles with exceptionally high drug loading by sequential nanoprecipitation
Liu, Yun, Yang, Guangze, Baby, Thejus, Tengjisi, Chen, Dong, Weitz, David A. and Zhao, Chun-Xia (2020). Stable polymer nanoparticles with exceptionally high drug loading by sequential nanoprecipitation. Angewandte Chemie International Edition, 59 (12) ange.201913539, 4720-4728. doi: 10.1002/anie.201913539
Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma
Ruan, Qi, Wang, Haolu, Burke, Leslie J., Bridle, Kim R., Li, Xinxing, Zhao, Chun-Xia, Crawford, Darrell H. G., Roberts, Michael S. and Liang, Xiaowen (2020). Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma. International Journal of Cancer, 147 (6) ijc.32899, 1519-1527. doi: 10.1002/ijc.32899
Formulation of nanoparticles using mixing-induced nanoprecipitation for drug delivery
Liu, Yun, Yang, Guangze, Zou, Da, Hui, Yue, Nigam, Krishna, Middelberg, Anton P. J. and Zhao, Chun-Xia (2020). Formulation of nanoparticles using mixing-induced nanoprecipitation for drug delivery. Industrial and Engineering Chemistry Research, 59 (9) acs.iecr.9b04747, 4134-4149. doi: 10.1021/acs.iecr.9b04747
Bioinspired core–shell nanoparticles for hydrophobic drug delivery
Yang, Guangze, Liu, Yun, Wang, Haofei, Wilson, Russell, Hui, Yue, Yu, Lei, Wibowo, David, Zhang, Cheng, Whittaker, Andrew K., Middelberg, Anton P. J. and Zhao, Chun‐Xia (2019). Bioinspired core–shell nanoparticles for hydrophobic drug delivery. Angewandte Chemie, 131 (40), 14495-14502. doi: 10.1002/ange.201908357
Evaluation of baiting fipronil-loaded silica nanocapsules against termite colonies in fields
Peters, Brenton C., Wibowo, David, Yang, Guang-Ze, Hui, Yue, Middelberg, Anton P. J. and Zhao, Chun-Xia (2019). Evaluation of baiting fipronil-loaded silica nanocapsules against termite colonies in fields. Heliyon, 5 (8) e02277, e02277. doi: 10.1016/j.heliyon.2019.e02277
Li, Wei, Wang, Hao-Fei, Li, Zhi-Yong, Wang, Tong and Zhao, Chun-Xia (2019). Numerical investigation of drug transport from blood vessels to tumour tissue using a tumour-vasculature-on-a-chip. Chemical Engineering Science, 208 115155, 115155. doi: 10.1016/j.ces.2019.115155
Bioinspired core-shell nanoparticles for hydrophobic drug delivery
Yang, Guangze, Liu, Yun, Wang, Haofei, Wilson, Russell, Hui, Yue, Yu, Lei, Wibowo, David, Zhang, Cheng, Whittaker, Andrew K., Middelberg, Anton P. J. and Zhao, Chun-Xia (2019). Bioinspired core-shell nanoparticles for hydrophobic drug delivery. Angewandte Chemie (International Edition), 58 (40) ange.201908357, 14357-14364. doi: 10.1002/anie.201908357
Role of nanoparticle mechanical properties in cancer drug delivery
Hui, Yue, Yi, Xin, Hou, Fei, Wibowo, David, Zhang, Fan, Zhao, Dongyuan, Gao, Huajian and Zhao, Chun-Xia (2019). Role of nanoparticle mechanical properties in cancer drug delivery. ACS Nano, 13 (7) acsnano.9b03924, 7410-7424. doi: 10.1021/acsnano.9b03924
Kong, Linlin, Chen, Ran, Wang, Xingzheng, Zhao, Chun-Xia, Chen, Qiushui, Hai, Mingtan, Chen, Dong, Yang, Zhenzhong and Weitz, David A. (2019). Controlled co-precipitation of biocompatible colorant-loaded nanoparticles by microfluidics for natural color drinks. Lab on a Chip, 19 (12), 2089-2095. doi: 10.1039/c9lc00240e
Ran, Rui, Wang, Hao-Fei, Hou, Fei, Liu, Yun, Hui, Yue, Petrovsky, Nikolai, Zhang, Fan and Zhao, Chun-Xia (2019). A microfluidic tumor-on-a-chip for assessing multifunctional liposomes' tumor targeting and anticancer efficacy. Advanced Healthcare Materials, 8 (8) 1900015, e1900015. doi: 10.1002/adhm.201900015
Yu, Lei, Sun, Qi, Hui, Yue, Seth, Arjun, Petrovsky, Nikolai and Zhao, Chun-Xia (2019). Microfluidic formation of core-shell alginate microparticles for protein encapsulation and controlled release. Journal of Colloid and Interface Science, 539, 497-503. doi: 10.1016/j.jcis.2018.12.075
Wibowo, David and Zhao, Chun-Xia (2019). Recent achievements and perspectives for large-scale recombinant production of antimicrobial peptides. Applied Microbiology and Biotechnology, 103 (2), 659-671. doi: 10.1007/s00253-018-9524-1
A numerical investigation of drug extravasation using a tumour-vasculature microfluidic device
Li, Wei, Wang, Hao-Fei, Kuruneru, Sahan T. W., Wang, Tong, Sauret, Emilie, Li, Zhi-Yong, Zhao, Chun-Xia and Gu, Yuan-Tong (2018). A numerical investigation of drug extravasation using a tumour-vasculature microfluidic device. Microfluidics and Nanofluidics, 22 (12) 143. doi: 10.1007/s10404-018-2165-y
Tumor-vasculature-on-a-chip for investigating nanoparticle extravasation and tumor accumulation
Wang, Hao-Fei, Ran, Rui, Liu, Yun, Hui, Yue, Zeng, Bijun, Chen, Dong, Weitz, David A. and Zhao, Chun-Xia (2018). Tumor-vasculature-on-a-chip for investigating nanoparticle extravasation and tumor accumulation. ACS Nano, 12 (11) acsnano.8b06846, 11600-11609. doi: 10.1021/acsnano.8b06846
Sun, Qi, Tan, Say Hwa, Chen, Qiushui, Ran, Rui, Hui, Yue, Chen, Dong and Zhao, Chun-Xia (2018). Microfluidic formation of coculture tumor spheroids with stromal cells as a novel 3D tumor model for drug testing. ACS Biomaterials Science & Engineering, 4 (12) acsbiomaterials.8b00904, 4425-4433. doi: 10.1021/acsbiomaterials.8b00904
Ran, Rui, Wang, Haofei, Liu, Yun, Hui, Yue, Sun, Qi, Seth, Arjun, Wibowo, David, Chen, Dong and Zhao, Chun-Xia (2018). Microfluidic self-assembly of a combinatorial library of single- and dual-ligand liposomes for in vitro and in vivo tumor targeting. European Journal of Pharmaceutics and Biopharmaceutics, 130, 1-10. doi: 10.1016/j.ejpb.2018.06.017
Synergetic combinations of dual-targeting ligands for enhanced in vitro and in vivo tumor targeting
Liu, Yun, Hui, Yue, Ran, Rui, Yang, Guang-Ze, Wibowo, David, Wang, Hao-Fei, Middelberg, Anton P. J. and Zhao, Chun-Xia (2018). Synergetic combinations of dual-targeting ligands for enhanced in vitro and in vivo tumor targeting. Advanced Healthcare Materials, 7 (15) 1800106, e1800106. doi: 10.1002/adhm.201800106
Understanding the effects of nanocapsular mechanical property on passive and active tumor targeting
Hui, Yue, Wibowo, David, Liu, Yun, Ran, Rui, Wang, Hao-Fei, Seth, Arjun, Middelberg, Anton P. J. and Zhao, Chun-Xia (2018). Understanding the effects of nanocapsular mechanical property on passive and active tumor targeting. ACS Nano, 12 (3), 2846-2857. doi: 10.1021/acsnano.8b00242
Sun, Baode, Wibowo, David, Middelberg, Anton P. J. and Zhao, Chun-Xia (2018). Cost-effective downstream processing of recombinantly produced pexiganan peptide and its antimicrobial activity. AMB Express, 8 (1) 6, 6. doi: 10.1186/s13568-018-0541-3
Design and production of a novel antimicrobial fusion protein in Escherichia coli
Sun, Baode, Wibowo, David, Sainsbury, Frank and Zhao, Chun-Xia (2018). Design and production of a novel antimicrobial fusion protein in Escherichia coli. Applied Microbiology and Biotechnology, 102 (20), 8763-8772. doi: 10.1007/s00253-018-9319-4
Biocompatible amphiphilic hydrogel-solid dimer particles as colloidal surfactants
Chen, Dong, Amstad, Esther, Zhao, Chun-Xia, Cai, Liheng, Fan, Jing, Chen, Qiushui, Hai, Mingtan, Koehler, Stephan, Zhang, Huidan, Liang, Fuxin, Yang, Zhenzhong and Weitz, David A (2017). Biocompatible amphiphilic hydrogel-solid dimer particles as colloidal surfactants. ACS Nano, 11 (12), 11978-11985. doi: 10.1021/acsnano.7b03110
Chen, Dong, Zhao, Chun-Xia, Lagoin, Camille, Hai, Mingtan, Arriaga, Laura R., Koehler, Stephan, Abbaspourrad, Alireza and Weitz, David A. (2017). Dispersing hydrophobic natural colourant β-carotene in shellac particles for enhanced stability and tunable colour. Royal Society Open Science, 4 (12) 170919, 170919. doi: 10.1098/rsos.170919
Multiphase microfluidic synthesis of micro- and nanostructures for pharmaceutical applications
Ran, Rui, Sun, Qi, Baby, Thejus, Wibowo, David, Middelberg, Anton P. J. and Zhao, Chun-Xia (2017). Multiphase microfluidic synthesis of micro- and nanostructures for pharmaceutical applications. Chemical Engineering Science, 169, 78-96. doi: 10.1016/j.ces.2017.01.008
Baby, Thejus, Liu, Yun, Middelberg, Anton P. J. and Zhao, Chun-Xia (2017). Fundamental studies on throughput capacities of hydrodynamic flow-focusing microfluidics for producing monodisperse polymer nanoparticles. Chemical Engineering Science, 169, 128-139. doi: 10.1016/j.ces.2017.04.046
Design of modular peptide surfactants and their surface activity
Wang, Hao-Fei, Wibowo, David, Shao, Zhengzhong, Middelberg, Anton P. J. and Chun-Xia Zhao (2017). Design of modular peptide surfactants and their surface activity. Langmuir, 33 (32), 7957-7967. doi: 10.1021/acs.langmuir.7b01382
Biocompatible microcapsules with a water core templated from single emulsions
Kong, Linlin, Amstad, Esther, Hai, Mingtan, Ke, Xinyou, Chen, Dong, Zhao, Chun-Xia and Weitz, David A. (2017). Biocompatible microcapsules with a water core templated from single emulsions. Chinese Chemical Letters, 28 (9), 1897-1900. doi: 10.1016/j.cclet.2017.07.017
Zhao, Fangyi, Guo, Hui, Zhang, Zhidong, Ye, John, Liu, Longlong, Zhao, Chun-Xia and Shao, Zhengzhong (2017). Conformation and self-assembly changes of isomeric peptide amphiphiles influenced by switching tyrosine in the sequences. Journal of Materials Chemistry B, 5 (26), 5189-5195. doi: 10.1039/c7tb00736a
Interfacial films formed by a biosurfactant modularized with a silken tail
Wibowo, David, Wang, Hao-Fei, Shao, Zhengzhong, Middelberg, Anton P. J. and Zhao, Chun-Xia (2017). Interfacial films formed by a biosurfactant modularized with a silken tail. The Journal of Physical Chemistry C, 121 (27), 14658-14667. doi: 10.1021/acs.jpcc.7b03807
Biomimetic silica nanocapsules for tunable sustained release and cargo protection
Yang, Guang-Ze, Wibowo, David, Yun, Jung-Ho, Wang, Lianzhou, Middelberg, Anton P. J. and Zhao, Chun-Xia (2017). Biomimetic silica nanocapsules for tunable sustained release and cargo protection. Langmuir, 33 (23), 5777-5785. doi: 10.1021/acs.langmuir.7b00590
Controlled generation of ultrathin-shell double emulsions and studies on their stability
Zhao, Chun-Xia, Chen, Dong, Hui, Yue, Weitz, David A. and Middelberg, Anton P. J. (2017). Controlled generation of ultrathin-shell double emulsions and studies on their stability. ChemPhysChem, 18 (10), 1393-1399. doi: 10.1002/cphc.201601334
Collective generation of milliemulsions by step-emulsification
Huang, Xing, Eggersdorfer, Max, Wu, Jinrong, Zhao, Chun-Xia, Xu, Zhongbin, Chen, Dong and Weitz, David A. (2017). Collective generation of milliemulsions by step-emulsification. RSC Advances, 7 (24), 14932-14938. doi: 10.1039/c7ra00935f
Wibowo, David, Yang, Guang-Ze, Middelberg, Anton P.J. and Zhao, Chun-Xia (2017). Non-chromatographic bioprocess engineering of a recombinant mineralizing protein for the synthesis of silica nanocapsules. Biotechnology and Bioengineering, 114 (2), 335-343. doi: 10.1002/bit.26079
From folding to function: design of a new switchable biosurfactant protein
Zhao, Chun-Xia, Dwyer, Mirjana, Yu, Lei and Middelberg, Anton P. J. (2017). From folding to function: design of a new switchable biosurfactant protein. ChemPhysChem, 18 (5), 488-492. doi: 10.1002/cphc.201601277
Zhao, Liang, Cavallaro, Antonino S., Wibowo, David, Zhang, Bing, Zhang, Jun, Mitter, Neena, Yu, Chengzhong, Zhao, Chun-Xia and Middelberg, Anton P. J. (2017). A partially purified outer membrane protein VirB9-1 for low-cost nanovaccines against Anaplasma marginale. Vaccine, 35 (1), 77-83. doi: 10.1016/j.vaccine.2016.11.037
Microfluidic synthesis of multifunctional liposomes for tumour targeting
Ran, Rui, Middelberg, Anton P. J. and Zhao, Chun-Xia (2016). Microfluidic synthesis of multifunctional liposomes for tumour targeting. Colloids and Surfaces B: Biointerfaces, 148, 402-410. doi: 10.1016/j.colsurfb.2016.09.016
Interfacial engineering for silica nanocapsules
Wibowo, David, Hui, Yue, Middelberg, Anton P. J. and Zhao, Chun-Xia (2016). Interfacial engineering for silica nanocapsules. Advances in Colloid and Interface Science, 236, 83-100. doi: 10.1016/j.cis.2016.08.001
Stable ultrathin-shell double emulsions for controlled release
Zhao, Chun-Xia, Chen, Dong, Hui, Yue, Weitz, David A. and Middelberg, Anton P. J. (2016). Stable ultrathin-shell double emulsions for controlled release. ChemPhysChem, 17 (11), 1553-1556. doi: 10.1002/cphc.201600142
Zhao, Liang, Mahony, Donna, Cavallaro, Antonino S., Zhang, Bing, Zhang, Jun, Deringer, James R., Brown, Wendy C., Zhao, Chun-Xia, Yu, Chengzhong, Mitter, Neena and Middelberg, Anton P. J. (2016). Immunogenicity of Outer Membrane Proteins VirB9-1 and VirB9-2, a Novel Nanovaccine against Anaplasma marginale. PLoS One, 11 (4) e0154295, e0154295. doi: 10.1371/journal.pone.0154295
Hui, Yue, Wibowo, David and Zhao, Chun-Xia (2016). Insights into the role of biomineralizing peptide surfactants on making nanoemulsion-templated silica nanocapsules. Langmuir, 32 (3), 822-830. doi: 10.1021/acs.langmuir.5b03811
Wibowo, David, Zhao, Chun-Xia and Middelberg, Anton P. J. (2015). Interfacial biomimetic synthesis of silica nanocapsules using a recombinant catalytic modular protein. Langmuir, 31 (6), 1999-2007. doi: 10.1021/la504684g
A simple and low-cost platform technology for producing pexiganan antimicrobial peptide in E. coli
Zhao, Chun-Xia, Dimitrijev Dwyer, Mirjana, Yu, Alice Lei, Wu, Yang, Fang, Sheng and Middelberg, Anton P. J. (2015). A simple and low-cost platform technology for producing pexiganan antimicrobial peptide in E. coli. Biotechnology and Bioengineering, 112 (5), 957-964. doi: 10.1002/bit.25505
Wibowo, David, Zhao, Chun-Xia, Peters, Brenton C. and Middelberg, Anton P. J. (2014). Sustained release of fipronil insecticide in Vitro and in Vivo from biocompatible silica nanocapsules. Journal of Agricultural and Food Chemistry, 62 (52), 12504-12511. doi: 10.1021/jf504455x
Titania microparticles using a facile microfluidic mass-transfer control method
Zhao, Chun-Xia and Middelberg, Anton P. J. (2014). Titania microparticles using a facile microfluidic mass-transfer control method. Chemical Engineering Science, 112, 10-14. doi: 10.1016/j.ces.2014.03.009
Zhao, Liang, Seth, Arjun, Wibowo, Nani, Zhao, Chun-Xia, Mitter, Neena, Yu, Chengzhong and Middelberg, Anton P. J. (2014). Nanoparticle vaccines. Vaccine, 32 (3), 327-337. doi: 10.1016/j.vaccine.2013.11.069
Emulsion-templated silica nanocapsules formed using bio-inspired silicification
Wibowo, David, Zhao, Chun-Xia and Middelberg, Anton P. J. (2014). Emulsion-templated silica nanocapsules formed using bio-inspired silicification. Chemical Communications, 50 (77), 11325-11328. doi: 10.1039/c4cc04904g
Multiphase flow microfluidics for the production of single or multiple emulsions for drug delivery
Zhao, Chun-Xia (2013). Multiphase flow microfluidics for the production of single or multiple emulsions for drug delivery. Advanced Drug Delivery Reviews, 65 (11-12), 1420-1446. doi: 10.1016/j.addr.2013.05.009
Zhao, Chun-Xia and Middelberg, Anton P. J. (2013). One-step fabrication of titania hollow spheres by controlled interfacial reaction in a droplet-based microfluidic system. Microfluidics and Nanofluidics, 14 (3-4), 703-709. doi: 10.1007/s10404-012-1088-2
Zhao, Chun-Xia, Yu, Lei and Middelberg, Anton P. J. (2013). Magnetic mesoporous silica nanoparticles end-capped with hydroxyapatite for pH-responsive drug release. Journal of Materials Chemistry B, 1 (37), 4828-4833. doi: 10.1039/c3tb20641f
Microfluidic synthesis of monodisperse hierarchical silica particles with raspberry-like morphology
Zhao, Chun-Xia and Middelberg, Anton P. J. (2013). Microfluidic synthesis of monodisperse hierarchical silica particles with raspberry-like morphology. RSC Advances, 3 (44), 21227-21230. doi: 10.1039/c3ra42362j
We, Ke-Jun, Zhao, Chun-Xia and He, Chao-Hong (2012). Development of a group contribution method for determination of thermal conductivity of ionic liquids. Fluid Phase Equilibria, 339, 10-14. doi: 10.1016/j.fluid.2012.11.024
Investigation of convective heat transfer with liquids in microtubes
Wu, Ke-Jun, Zhao, Chun-Xia and He, Chao-Hong (2012). Investigation of convective heat transfer with liquids in microtubes. Industrial & Engineering Chemistry Research, 51 (27), 9386-9395. doi: 10.1021/ie301174j
We, Ke-Jun, Zhao, Chun-Xia and Chao-Hong He (2012). A simple corresponding-states group contribution method for estimating surface tension of ionic liquids. Fluid Phase Equilibria, 328, 42-48. doi: 10.1016/j.fluid.2012.05.021
Microfluidic elucidation of the effects of interfacial rheology on droplet deformation
Zhao, Chun-Xia, Rondeau, Elisabeth, Cooper-White, Justin J. and Middelberg, Anton P. J. (2012). Microfluidic elucidation of the effects of interfacial rheology on droplet deformation. Industrial and Engineering Chemistry Research, 51 (4), 2021-2029. doi: 10.1021/ie200631m
Design of low-charge peptide sequences for high-yield formation of titania nanoparticles
Zhao, Chun-Xia, Yu, Lei and Middelberg, Anton P. J. (2012). Design of low-charge peptide sequences for high-yield formation of titania nanoparticles. RSC Advances, 2 (4), 1292-1295. doi: 10.1039/c2ra00726f
Effects of fluid-fluid interfacial elasticity on droplet formation in microfluidic devices
Zhao, Chun-Xia, Miller, Erik, Cooper-White, Justin J. and Middelberg, Anton P.J. (2011). Effects of fluid-fluid interfacial elasticity on droplet formation in microfluidic devices. AIChE Journal, 57 (7), 1669-1677. doi: 10.1002/aic.12382
Nanoparticle synthesis in microreactors
Zhao, Chun-Xia, He, Lizhong, Qiao, Shizhang and Middelberg, Anton P.J. (2011). Nanoparticle synthesis in microreactors. Chemical Engineering Science, 66 (7), 1463-1479. doi: 10.1016/j.ces.2010.08.039
Zhao, Chun-Xia and Middelberg, Anton P. J. (2011). Two-phase microfluidic flows. Chemical Engineering Science, 66 (7), 1394-1411. doi: 10.1016/j.ces.2010.08.038
Imaging the effects of peptide bio-surfactants on droplet deformation in a Taylor-Couette shear cell
Fridjonsson, Einar O., Chandrasekera, Thusara C., Sederman, Andrew J., Johns, Michael L., Zhao, Chun-Xia and Middelberg, Anton P. J. (2011). Imaging the effects of peptide bio-surfactants on droplet deformation in a Taylor-Couette shear cell. Soft Matter, 7 (6), 2961-2967. doi: 10.1039/c0sm00951b
Mass transfer and separation criteria for high-speed countercurrent chromatography
Zhao, Chun-Xia and He, Chao-Hong (2011). Mass transfer and separation criteria for high-speed countercurrent chromatography. AIChE Journal, 57 (2), 359-372. doi: 10.1002/aic.12282
A nonlinear active learning based on AUC optimization and its application to obstacle detection
Han, Guang, Zhao, Chunxia and Hu, Xuelei (2010). A nonlinear active learning based on AUC optimization and its application to obstacle detection. Jiqiren, 32 (3), 344-351. doi: 10.3724/SP.J.1218.2010.00344
Microfluidic mass-transfer control for the simple formation of complex multiple emulsions
Zhao, Chun-Xia and Middelberg, Anton P. J. (2009). Microfluidic mass-transfer control for the simple formation of complex multiple emulsions. Angewandte Chemie-International Edition, 48 (39), 7208-7211. doi: 10.1002/anie.200902485
Axial dispersion coefficient in high-speed counter-current chromatography
Zhao, Chun-Xia, Xua, Ya-Lan and He, Chao-Hong (2009). Axial dispersion coefficient in high-speed counter-current chromatography. Journal of Chromatography A, 1216 (24), 4841-4846. doi: 10.1016/j.chroma.2009.04.020
Wang, Fei-Na, Yu, Jing, Zhao, Chun-Xia and Qian, Fang-Jing (2008). Optimization of preparation of Atractylodes macrocephala Volatile-β-cyclodextrin complex by response surface methodology. Zhejiang Daxue Xuebao (Gongxue Ban)/Journal of Zhejiang University (Engineering Science), 42 (12), 2160-2165. doi: 10.3785/j.issn.1008-973X.2008.12.022
Fang, Sheng, Zhao, Chun-Xia and He, Chao-Hong (2008). Densities and viscosities of binary mixtures of tri-n-butyl phosphate + cyclohexane, + n-heptane at T = (288.15, 293.15, 298.15, 303.15, and 308.15) K. Journal of Chemical and Engineering Data, 53 (9), 2244-2246. doi: 10.1021/je8003707
Fang, Sheng, Zhao, Chun-Xia, He, Chao-Hong, Liu, Jian-Qing and Sun, Jiang-Hao (2008). Densities and viscosities of binary mixtures of tris(2-ethylhexyl) phosphate + cyclohexane or n-hexane at T = (293.15, 298.15, and 303.15) K and p = 0.1 MPa. Journal of Chemical and Engineering Data, 53 (11), 2718-2720. doi: 10.1021/je8006138
Retention of the stationary phase for high-speed countercurrent chromatography
He, Chao-Hong and Zhao, Chun-Xia (2007). Retention of the stationary phase for high-speed countercurrent chromatography. AIChE Journal, 53 (6), 1460-1471. doi: 10.1002/aic.11185
Sample capacity in preparative high-speed counter-current chromatography
Zhao, Chun-Xia and He, Chao-Hong (2007). Sample capacity in preparative high-speed counter-current chromatography. Journal of chromatography. A, 1146 (2), 186-192. doi: 10.1016/j.chroma.2007.01.105
Zhao, Chun-Xia and He, Chao-Hong (2007). Solubility of Atractylenolide III in Hexane, Ethyl Acetate, Diethyl Ether, and Ethanol from (283.2 to 323.2) K. Journal of Chemical and Engineering Data, 52 (4), 1223-1225. doi: 10.1021/je6005482
Zhao, Chunxia and He, Chaohong (2006). Preparative isolation and purification of atractylon and atractylenolide III from the Chinese medicinal plant Atractylodes macrocephala by high-speed counter-current chromatography. Journal of Separation Science, 29 (11), 1630-1636. doi: 10.1002/jssc.200500464
Deep Relevant Feature Focusing for Out-of-Distribution Generalization
Wang, Fawu, Zhang, Kang, Liu, Zhengyu, Yuan, Xia and Zhao, Chunxia (2022). Deep Relevant Feature Focusing for Out-of-Distribution Generalization. 5th Chinese Conference on Pattern Recognition and Computer Vision PRCV 2022, Shenzhen, China, 4 - 7 November 2022. Cham, Switzerland: Springer. doi: 10.1007/978-3-031-18907-4_19
Automatic live and dead cell classification via hyperspectral imaging
Chen, He, Ho, Benjamin, Wang, Haofei, Tan, Say Hwa, Zhao, Chun-Xia, Nguyen, Nam-Trung, Gao, Yongsheng and Zhou, Jun (2019). Automatic live and dead cell classification via hyperspectral imaging. Workshop on Hyperspectral Imaging and Signal Processing: Evolution in Remote Sensing (WHISPERS), Amsterdam, Netherlands, 24-26 September 2019. Piscataway, NJ, United States: IEEE Computer Society. doi: 10.1109/WHISPERS.2019.8921136
Sun, Qi, Zhao, Chun-Xia, Nguyen, Nam-Trung and Tan, Say Hwa (2017). A droplet-based microfluidic platform for the study of the effect of oscillation on the growth of E.coli. 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017, Savannah, GA, United States, 22-26 October 2017. San Diego, CA, United States: Chemical and Biological Microsystems Society.
Bio-inspired nanomaterials for controlled release
Zhao, Chun-Xia, Wibowo, David and Middelberg, Anton P. J. (2015). Bio-inspired nanomaterials for controlled release. 2015 AIChE Annual Meeting, Salt Lake City, UT, United States, 8-13 November 2015.
Double emulsions by a one-step solvent shift method
Zhao, Chun-Xia and Middelberg, Anton P. J. (2010). Double emulsions by a one-step solvent shift method. 40th Annual Australasian Chemical and Process Engineering Conference, Adelaide, SA, Australia, 26-29 September 2010. Barton, ACT, Australia: Engineers Australia.
Interfacial elasticity affects droplet formation in microfluidic channels
Zhao, Chun-Xia, Miller, Erik, Cooper-White, Justin J., Dexter, Annette F. and Middelberg, Anton P. J. (2009). Interfacial elasticity affects droplet formation in microfluidic channels. 8th World Congress of Chemical Engineering, Montreal, Canada, 23 - 27 August, 2009.
The influence of interfacial viscoelasticity on droplet deformation in microchannels
Zhao, Chun-Xia, Rondeau, Elisabeth, Miller, Erik, Cooper-White, Justin J., Dexter, Annette F. and Middelberg, Anton P.J. (2009). The influence of interfacial viscoelasticity on droplet deformation in microchannels. WCCE8: 8th World Congress of Chemical Engineering, Montréal, QC, Canada, 23-27 August 2009.
Separation for the mixture of petroleum ether (60-90?) and ethyl acetate
Luo, D. Z., Zhao, C. X. and He, C. H. (2005). Separation for the mixture of petroleum ether (60-90?) and ethyl acetate. China/USA/Japan Joint Chemical Engineering Conference, Beijing, Oct 11-13, 2005.
Mechanical modulation of particle-cell interactions
(2021) ARC Discovery Projects
Precision-engineered hybrid core-shell materials
(2020–2021) ARC Discovery Projects
Engineering encapsulation technology for animal feed manufacture
(2019–2023) Bioproton Pty Ltd
A new physical strategy for therapeutic delivery
(2019) UQ Development Fellowships
Imaging in the nano-scale age: terahertz and millimetre wave microanalysis
(2018) UQ Major Equipment and Infrastructure
In vivo optical imaging into the next generation
(2018) UQ Research Facilities Infrastructure Grants
Platform technologies for next generation single dose vaccine delivery
(2016–2017) UQ Collaboration and Industry Engagement Fund - FirstLink
Exosome and Bio/Nanoparticle Characterisation Facility
(2016) UQ Major Equipment and Infrastructure
Platform technologies for multifunctional nanocarrier systems
(2015–2020) ARC Future Fellowships
Next generation core-shell materials based on biomolecular dual-templating
(2015–2019) ARC Discovery Projects
Engineering improved technology for nanoparticle-based adjuvant manufacture
(2015–2018) ARC Linkage Projects
UQ Advancing Women Researchers Grant 2015 Round 1 - Dr Chunxia Zhao
(2015–2016) UQ Advancing Women Researchers Grants
pH-responsive core-shell mesoporous silica nanocomposites for bioimaging and targeted drug delivery
(2012) UQ Early Career Researcher
Engineered nanoporous materials and composites having hierarchical structures by emulsion templating
(2011–2014) ARC Discovery Projects
Biomimetic Synthesis of Inorganic Nanoparticles using Microfluidic Crystals
(2010–2012) UQ New Staff Research Start-Up Fund
Precision-engineered hybrid core-shell materials
Doctor Philosophy — Principal Advisor
Other advisors:
Stimuli-responsive soft materials based on biomolecules
Doctor Philosophy — Principal Advisor
Other advisors:
Engineering encapsulation technology for animal feed manufacture
Doctor Philosophy — Principal Advisor
Other advisors:
Evaluation of polymer nanomedicines in treating solid tumours
Doctor Philosophy — Associate Advisor
Other advisors:
Novel Reagent Technologies for Arsenic Minerals
Doctor Philosophy — Associate Advisor
Bioinspired core-shell silica nanomaterials and their nano-bio interactions
(2022) Doctor Philosophy — Principal Advisor
Fundamental studies on extracellular matrix mimicking hydrogels for in vitro tumor models
(2022) Doctor Philosophy — Principal Advisor
Bioinspired Magnetic Nanomaterials for Drug Delivery
(2021) Doctor Philosophy — Principal Advisor
Other advisors:
Biomimetic chip platforms for studying drug delivery systems
(2020) Doctor Philosophy — Principal Advisor
Core-Shell Nanomaterials for Drug Delivery and Controlled Release
(2020) Doctor Philosophy — Principal Advisor
Polymeric Nanoparticles for Drug Delivery
(2020) Doctor Philosophy — Principal Advisor
Bio-inspired silica nanocapsules for understanding in vitro and in vivo nano-bio interactions
(2019) Doctor Philosophy — Principal Advisor
Microfluidic Platform for Multifunctional Liposome Preparation and Evaluation
(2019) Doctor Philosophy — Principal Advisor
Microfluidic synthesis of biodegradable polymeric nanoparticles for drug delivery
(2018) Doctor Philosophy — Principal Advisor
(2018) Master Philosophy — Principal Advisor
Development of three-dimensional microfluidic models for therapeutic testing
(2017) Master Philosophy — Principal Advisor
Bio-inspired oil-core silica-shell nanocapsules for controlled-release applications
(2015) Doctor Philosophy — Principal Advisor
Development of artificial mesenchymal stem cells for hepatocellular carcinoma drug delivery
(2023) Doctor Philosophy — Associate Advisor
Other advisors:
Human mesenchymal stem cell-derived liver-on-a-chip for the study of cell migration
(2023) Doctor Philosophy — Associate Advisor
Other advisors:
Optimisation of Peptide-Stabilised Emulsion Engineering Using Microfluidics
(2023) Doctor Philosophy — Associate Advisor
Development of Sustained-Release Subunit Nanovaccines Against Anaplasma marginale
(2019) Doctor Philosophy — Associate Advisor
Other advisors:
Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.
Precision engineering core-shell nanomaterials for drug delivery
Project 1
New platform technologies for making hybrid core-shell materials
Poor water solubility of many chemical actives hinders the development of new pharmaceutical, agricultural, food products. For example, 40% of approved drugs and 90% of drugs in development are water-insoluble. New methods are needed for more efficient formulation and delivery of these drugs. This project will develop new platform technologies for making hybrid core-shell materials with exceptionally high drug loading capacity and programmed drug release, delivering new technologies for the manufacture of high-value pharmaceutical product for various applications.
This project is supported by an ARC Discovery Project. Two PhD scholarships are available.
Project 2
Fast microfluidic screening platform for specific binding
Facile and quick platforms will be developed to screen biomolecule candidates for selective binding to specific metals. The screened biomolecules will be synthesized either using chemical synthesis methods or biological cell expression systems. The selective adsorption of the biomolecules on the target valuable metals will be systematically studied.
This project is supported by an ARC Centre of Excellence project. PhD scholarship is available.
Project 3
Development of stimuli responsive biomolecules for controlling different interfaces
Peptides or proteins are informational polymers made up of amino acids and are increasingly viewed as key building blocks to achieve specific functions owing to their biocompatibility, sustainability, and ease of functionalization, coupled with facile methods for their economic manufacture. Enabled by the diversity of the 20 naturally occurring amino acids, there is a large sequence and structural solution space for design. This project will explore the functionality of biomolecules to stabilise foams or emulsions, and the potential for switching that functionality based on different switching mechanisms.
This project is supported by an ARC Centre of Excellence project. PhD scholarship is available.
Please email z.chunxia@uq.edu.au with your CV, including a summary of academic qualifications, work and research experience, and publication list.