Dr Eva Baxter

Research Fellow

UQ Centre for Clinical Research
Faculty of Medicine
e.baxter@uq.edu.au
+61 7 334 66049

Overview

Research Interests

  • Endometrial cancer
  • Biomarkers
  • Molecular biology

Qualifications

  • Doctor of Philosophy, University of Edinburgh

Publications

  • Obermair, Andreas, Nicklin, Jim, Gebski, Val, Hayes, Sandra C., Graves, Nicholas, Mileshkin, Linda, Lin, Ming Yin, Beale, Phillip, Baxter, Eva, Robledo, Kristy, Salomon, Carlos, Hanna, George B. and Janda, Monika (2021). A phase III randomized clinical trial comparing sentinel node biopsy with no retroperitoneal node dissection in apparent early-stage endometrial cancer – ENDO-3: ANZGOG trial 1911/2020. International Journal of Gynecologic Cancer, 31 (12), 1595-1601. doi: 10.1136/ijgc-2021-003029

  • Obermair, Andreas, Baxter, Eva, Brennan, Donal J., McAlpine, Jessica N., Muellerer, Jennifer J., Amant, Frédéric, van Gent, Mignon D. J. M., Coleman, Robert L., Westin, Shannon N., Yates, Melinda S., Krakstad, Camilla and Janda, Monika (2020). Fertility-sparing treatment in early endometrial cancer: current state and future strategies. Obstetrics and Gynecology Science, 63 (4), 417-431. doi: 10.5468/ogs.19169

  • Baxter, Eva, Brennan, Donal J, McAlpine, Jessica N, Mueller, Jennifer J, Amant, Frédéric, van Gent, Mignon D J M, Huntsman, David G, Coleman, Robert L, Westin, Shannon N, Yates, Melinda S, Krakstad, Camilla, Quinn, Michael A, Janda, Monika and Obermair, Andreas (2020). Improving response to progestin treatment of low-grade endometrial cancer. International Journal of Gynecologic Cancer, 30 (11) ijgc-2020-001309, ijgc-2020. doi: 10.1136/ijgc-2020-001309

View all Publications

Available Projects

  • Gynaecological cancers are the third most common cancer type diagnosed in Australian women. Each year over 6,700 Australian women and girls are diagnosed with gynaecological cancer and almost a third will not survive their disease.

    We have a PhD opportunity available at the Queensland Centre for Gynaecological Cancer (QCGC) Research focusing on discovering and validating biomarkers that improve outcomes for women with gynaecological cancer. This project will involve working with clinical samples, conducting laboratory work, and analysing data.

    The successful applicant will work as part of the QCGC Research team at the Centre for Clinical Research, as well as collaborate with researchers, clinicians, consumers, and stakeholders from other organisations, including hospitals, pathology providers and the community.

  • Endometrial cancer originates from the inner layer of the uterus and is the fifth most common cancer in women. In Australia, the incidence is >3,000 cases per year and this is rising at a rate of 1% year on year, while globally over 400,000 patients are diagnosed annually. Current standard treatment requires surgical removal of the uterus, tubes, and ovaries (hysterectomy). Clinical management guidelines for early-stage endometrial cancer also prescribe lymph node dissection to determine (via histopathology) the extent of the disease, however, this may lead to treatment that is more extensive than necessary.

    We are currently running a phase III randomised clinical trial exploring the risks and benefits of lymph node dissection in clinical stage I endometrial cancer. The primary outcome of the trial is to determine the probability of disease-free survival at 4 years.

    This project focuses on assessing:

    • Patient-reported outcome measures, including health-related quality of life and fear of cancer recurrence
    • Perioperative outcomes, including intra- and postoperative adverse events
    • Lower-limb lymphoedema
    • Requirements for adjuvant treatment
    • Biomarkers to improve outcomes for patients

View all Available Projects

Publications

Journal Article

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.

  • Gynaecological cancers are the third most common cancer type diagnosed in Australian women. Each year over 6,700 Australian women and girls are diagnosed with gynaecological cancer and almost a third will not survive their disease.

    We have a PhD opportunity available at the Queensland Centre for Gynaecological Cancer (QCGC) Research focusing on discovering and validating biomarkers that improve outcomes for women with gynaecological cancer. This project will involve working with clinical samples, conducting laboratory work, and analysing data.

    The successful applicant will work as part of the QCGC Research team at the Centre for Clinical Research, as well as collaborate with researchers, clinicians, consumers, and stakeholders from other organisations, including hospitals, pathology providers and the community.

  • Endometrial cancer originates from the inner layer of the uterus and is the fifth most common cancer in women. In Australia, the incidence is >3,000 cases per year and this is rising at a rate of 1% year on year, while globally over 400,000 patients are diagnosed annually. Current standard treatment requires surgical removal of the uterus, tubes, and ovaries (hysterectomy). Clinical management guidelines for early-stage endometrial cancer also prescribe lymph node dissection to determine (via histopathology) the extent of the disease, however, this may lead to treatment that is more extensive than necessary.

    We are currently running a phase III randomised clinical trial exploring the risks and benefits of lymph node dissection in clinical stage I endometrial cancer. The primary outcome of the trial is to determine the probability of disease-free survival at 4 years.

    This project focuses on assessing:

    • Patient-reported outcome measures, including health-related quality of life and fear of cancer recurrence
    • Perioperative outcomes, including intra- and postoperative adverse events
    • Lower-limb lymphoedema
    • Requirements for adjuvant treatment
    • Biomarkers to improve outcomes for patients