Mr Mark Chatfield


Centre for Health Services Research
Faculty of Medicine
+61 7 3346 5042


A/Prof Mark D. Chatfield is a diligent, highly experienced biostatistician. He is especially knowledgeable about clinical trials at UQ.

In collaboration with other researchers, he has published over 170 times in academic journals and has been/is an investigator on 23 NHMRC/MRFF funded (>$46,000,000) studies (mostly clinical trials). He has co-supervised 4 PhD students to completion, and is currently an advisor to 5 PhD students.

He is regularly invited to be a statistical collaborator, advisor or consultant by researchers from:

- Centre for Clinical Research [UQCCR]

- School of Public Health [SPH]

- Child Health Research Centre [CHRC]

- Centre for Health Services Research [CHSR]

- Faculty of Health and Behavioural Sciences [HaBS]

In 2021, he won a Service Excellence Award for outstanding biostatistical support and collaboration with numerous medical researchers in the Faculty of Medicine. He is a main contributor to the Research and Statistical Support Service (RASSS). In 2020, he was awarded The Outstanding Mid-Career Researcher within CHSR.

He is an Honorary Fellow (Associate Professor, 2016-present) with Menzies School of Health Research, where he worked 2012-2017. He has also worked at QIMR Berghofer Medical Research Institute (2017-8), NHMRC Clinical Trials Centre, University of Sydney (2009-2012), UK MRC Human Nutrition Research (2006-9), Department of Public Health and Primary Care, University of Cambridge (2002-6).

Research Interests

  • Randomised Clinical/Controlled Trials (RCTs)
    I make significant contributions to funding applications, trial design, monitoring, analysis, presentation and interpretation. I have substantial involvement with trials of various designs, and have a good understanding of adaptive trials. I have been involved with methodological research into cluster randomised trials (ICC for binary outcomes), sample size, width of 95% CI. I am a member of the Australian Clinical Trials Alliance (ACTA) Statistics in Trials Interest Group (STInG) executive committee. I have judged ACTA's Excellence in Trial Statistics Award in recent years. I have been a NHMRC & MRFF trials grant review panel member.
  • Percentage differences/changes/errors
    I am currently thinking deeply about symmetric percentage differences: e.g. 100(A-B)/0.5(A+B)% and 100(lnA- lnB)%, asymmetry indices, Bland-Altman plots, immediate interpretation of parameters in models involving ln(Y), ln(odds), ln(rate), ln(X) etc., geometric means, log transformation and log scales.
  • Meta analysis
    While involved with different types of meta-analysis, I am especially interested in the meta-analysis of continuous outcomes from RCTs. I have taught meta-analysis in RevMan and Stata. I am a member of the Cochrane Statistical Methods Group.
  • Other stats
    I am a Fellow of the Royal Statistical Society (2002-present). I have reviewed many articles for The Lancet, and other journals. I have taught a one-day regression modelling in Stata workshop.
  • Stata statistical software
    I am a Stata expert, and have contributed several programs ( (1) table1_mc ... create "table 1" of baseline characteristics for a manuscript, (2) precombine... examine n ≥ 2 datasets before combining, (3) labeldatasyntax... produce syntax to label variables and values, given a data dictionary, (4) power tworates_zhu... calculate sample size or power for a two-sample test of rates, (5) ciwidth proportions_mc... calculate precision and power for a CI-based comparison of two independent proportions (RD, RR, or OR), (6) tolerance... calculate tolerance intervals (normal distribution), (7) skilmack... Skillings-Mack test (8) blandaltman... Bland-Altman plots featuring differences or %differences or ratios, with options to add a variety of lines and intervals


  • Master of Arts, Oxford
  • Bachelor of Arts in Mathematical Sciences, Oxf.
  • Master of Science Statistics, University of Southampton


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  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

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Featured Publications

Book Chapter

  • Fleming, Jane, Matthews, Fiona E., Chatfield, Mark and Brayne, Carol (2006). Population levels of mild cognitive impairment in England and Wales. Mild Cognitive Impairment: International Perspectives. (pp. 77-91) edited by Holly A. Tuokko and David F. Hultsch. New York, NY, United States: Taylor and Francis. doi: 10.4324/9780203782996

Journal Article

Conference Publication

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

Completed Supervision