The University of Queensland

Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis

Obonyo, Nchafatso G., Sela, Declan P., Raman, Sainath, Rachakonda, Reema, Schneider, Bailey, Hoe, Louise E. See, Fanning, Jonathon P., Bassi, Gianluigi Li, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2023). Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis. Systematic Reviews, 12 (1) 221. doi: 10.1186/s13643-023-02385-0

Adaptive clinical trials in pediatric critical care: a systematic review

Gilholm, Patricia, Ergetu, Endrias, Gelbart, Ben, Raman, Sainath, Festa, Marino, Schlapbach, Luregn J., Long, Debbie, Gibbons, Kristen S. and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (2023). Adaptive clinical trials in pediatric critical care: a systematic review. Pediatric Critical Care Medicine, 24 (9), 738-749. doi: 10.1097/pcc.0000000000003273

Longitudinal cohort study investigating neurodevelopmental and socioemotional outcomes in school-entry aged children after open heart surgery in Australia and New Zealand: the NITRIC follow-up study protocol

Long, Debbie, Anderson, Vicki A., Crossley, Louise, Sood, Nikita Tuli, Charles, Karina R., MacDonald, Anna D., Bora, Samudragupta, Pestell, Carmela F., Murrell, Kathryn, Pride, Natalie A., Anderson, Peter J., Badawi, Nadia, Rose, Brian, Baillie, Heidi, Masterson, Kate, Chumbes Flores, Jenipher, Sherring, Claire, Raman, Sainath, Beca, John, Erickson, Simon, Festa, Marino, Anderson, Benjamin W., Venugopal, Prem, Yim, Deane, Andrews, David, Cheung, Michael, Brizard, Christian, Gentles, Thomas L., Iyengar, Ajay ... Gibbons, Kristen S. (2023). Longitudinal cohort study investigating neurodevelopmental and socioemotional outcomes in school-entry aged children after open heart surgery in Australia and New Zealand: the NITRIC follow-up study protocol. BMJ Open, 13 (8) e075429, e075429. doi: 10.1136/bmjopen-2023-075429

Author Correction: Combined effects of sepsis and extracorporeal membrane oxygenation on left ventricular performance in a murine model

Kayumov, Mukhammad, Kim, Dowan, Raman, Sainath, MacLaren, Graeme, Jeong, In Seok and Cho, Hwa Jin (2023). Author Correction: Combined effects of sepsis and extracorporeal membrane oxygenation on left ventricular performance in a murine model. Scientific Reports, 13 (1) 1049, 1-1. doi: 10.1038/s41598-023-28375-9

Resuscitation Associated Endotheliopathy (PubMed)

Obonyo, Nchafatso G., Sela, Declan P., Raman, Sainath, Rachakonda, Reema, Schneider, Bailey, Hoe, Louise E. See, Fanning, Jonathon P., Bassi, Gianluigi Li, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2023). Resuscitation Associated Endotheliopathy (PubMed). searchRxiv, 2023. doi: 10.1079/searchrxiv.2023.00206

Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia

Gilholm, Patricia, Gibbons, Kristen, Lister, Paula, Harley, Amanda, Irwin, Adam, Raman, Sainath, Rice, Michael, Schlapbach, Luregn J. and Queensland Statewide Sepsis Collaborative (2023). Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia. BMJ Open, 13 (1) e061431, 1-25. doi: 10.1136/bmjopen-2022-061431

Effect of Saline vs gluconate/acetate–buffered solution vs lactate-buffered solution on serum chloride among children in the pediatric Intensive Care Unit: the SPLYT-P randomized clinical trial

Raman, Sainath, Gibbons, Kristen S., Mattke, Adrian, Schibler, Andreas, Trnka, Peter, Kennedy, Melanie, Le Marsney, Renate and Schlapbach, Luregn J. (2022). Effect of Saline vs gluconate/acetate–buffered solution vs lactate-buffered solution on serum chloride among children in the pediatric Intensive Care Unit: the SPLYT-P randomized clinical trial. JAMA Pediatrics, 177 (2), 122-131. doi: 10.1001/jamapediatrics.2022.4912

Combined effects of sepsis and extracorporeal membrane oxygenation on left ventricular performance in a murine model

Kayumov, Mukhammad, Kim, Dowan, Raman, Sainath, MacLaren, Graeme, Jeong, In Seok and Cho, Hwa Jin (2022). Combined effects of sepsis and extracorporeal membrane oxygenation on left ventricular performance in a murine model. Scientific Reports, 12 (1) 22181, 1-8. doi: 10.1038/s41598-022-26145-7

PP286 [Medical Workforce & Education » Staff well being /health (Stress, burnout, moral distress, spirituality)]: IMPACT OF A MINDFULNESS-BASED PROGRAM (MBP) ON PAEDATRIC INTENSIVE CARE STAFF WELLBEING

Joshi, R. S., Wiemers, M., Zahir, S. F. and Raman, S. (2022). PP286 [Medical Workforce & Education » Staff well being /health (Stress, burnout, moral distress, spirituality)]: IMPACT OF A MINDFULNESS-BASED PROGRAM (MBP) ON PAEDATRIC INTENSIVE CARE STAFF WELLBEING. Pediatric Critical Care Medicine, 23 (Supplement 1 11S). doi: 10.1097/01.pcc.0000900952.25047.fd

Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia

Blythe, Robin, Lister, Paula, Seaton, Robert, Harley, Amanda, Schlapbach, Luregn J., McPhail, Steven, Venkatesh, Bala, Irwin, Adam, Raman, Sainath, Schlapbach, Luregn, Harley, Amanda, Irwin, Adam, Graham, Nicolette, Thomson, Fiona, Owen, Kieran, Garrish, Kirsten, Sampson, Emma, Long, Debbie, George, Shane, Grimwood, Keith, Bell, Christa, Semple, Bethany, Adams, Claire, Brown, Josea, Maloney, Louise, Lister, Paula, Schofield, Scott, Thomas, Clare, Dejong, Liam ... the Queensland State-wide Sepsis Collaborative (2022). Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia. Scientific Reports, 12 (1) 10113, 10113. doi: 10.1038/s41598-022-14226-6

Designing support structures post sepsis in children: perspectives of the Queensland Paediatric Sepsis Program

Raman, Sainath, English, Alana, O'Keefe, Meagan, Harley, Amanda, Steele, Mary, Minogue, Jess, Weller, Kate, Long, Debbie, Irwin, Adam and Lister, Paula (2021). Designing support structures post sepsis in children: perspectives of the Queensland Paediatric Sepsis Program. Frontiers in Pediatrics, 9 759234, 759234. doi: 10.3389/fped.2021.759234

Metabolic resuscitation in pediatric sepsis: a narrative review

Schlapbach, Luregn J., de Oliveira, Claudio Flauzinho, Raman, Sainath and de Souza, Daniela (2021). Metabolic resuscitation in pediatric sepsis: a narrative review. Translational Pediatrics, 10 (10), 2678-2688. doi: 10.21037/tp-21-1

Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations

Tu, Quyen, Cotta, Menino, Raman, Sainath, Graham, Nicolette, Schlapbach, Luregn and Roberts, Jason A (2021). Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations. Expert Review of Clinical Pharmacology, 14 (11), 1-17. doi: 10.1080/17512433.2021.1961578

0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial

Raman, Sainath, Schibler, Andreas, Le Marsney, Renate, Trnka, Peter, Kennedy, Melanie, Mattke, Adrian, Gibbons, Kristen and Schlapbach, Luregn J. (2021). 0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial. Trials, 22 (1) 427. doi: 10.1186/s13063-021-05376-5

Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)

Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680

Priorities for paediatric critical care research: a modified Delphi study by the Australian and New Zealand Intensive Care Society Paediatric Study Group

Raman, Sainath, Brown, Georgia, Long, Debbie, Gelbart, Ben, Delzoppo, Carmel, Millar, Johnny, Erickson, Simon, Festa, Marino, Schlapbach, Luregn J., For the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) and Gibbons, Kristen (2021). Priorities for paediatric critical care research: a modified Delphi study by the Australian and New Zealand Intensive Care Society Paediatric Study Group. Critical Care and Resuscitation, 23 (2), 194-201. doi: 10.51893/2021.2.oa6

Resuscitation in Paediatric Sepsis Using Metabolic Resuscitation–A Randomized Controlled Pilot Study in the Paediatric Intensive Care Unit (RESPOND PICU): Study Protocol and Analysis Plan

Schlapbach, Luregn J., Gibbons, Kristen, Ridolfi, Roberta, Harley, Amanda, Cree, Michele, Long, Debbie, Buckley, David, Erickson, Simon, Festa, Marino, George, Shane, King, Megan, Singh, Puneet, Raman, Sainath, Bellomo, Rinaldo and The RESPOND PICU study investigators and the Australian New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2021). Resuscitation in Paediatric Sepsis Using Metabolic Resuscitation–A Randomized Controlled Pilot Study in the Paediatric Intensive Care Unit (RESPOND PICU): Study Protocol and Analysis Plan. Frontiers in Pediatrics, 9 663435, 1-10. doi: 10.3389/fped.2021.663435

Effects on organ donation of transition from apnoeic-oxygenation to radioisotope brain scanning to diagnose brain death in children

James, Tibballs, Sainath, Raman and Peter, Francis (2021). Effects on organ donation of transition from apnoeic-oxygenation to radioisotope brain scanning to diagnose brain death in children. Archives of Organ Transplantation, 1-7. doi: 10.17352/2640-7973.000017

Efficacy and safety of parenteral high-dose vitamin C therapy in pediatric patients: a scoping review

Yanase, Fumitaka, Raman, Sainath, Naorungroj, Thummaporn, McCarthy, Avril, Cree, Michele, Schlapbach, Luregn J and Bellomo, Rinaldo (2021). Efficacy and safety of parenteral high-dose vitamin C therapy in pediatric patients: a scoping review. Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 22 (6), 561-571. doi: 10.1097/PCC.0000000000002686

Acute kidney injury: epidemiology and course in critically ill children

Tai, Chian Wern, Gibbons, Kristen, Schibler, Andreas, Schlapbach, Luregn J. and Raman, Sainath (2021). Acute kidney injury: epidemiology and course in critically ill children. Journal of Nephrology, 35 (2), 559-565. doi: 10.1007/s40620-021-01071-5

The use of extracorporeal membrane oxygenation in children with acute fulminant myocarditis

Heinsar, Silver, Raman, Sainath, Suen, Jacky Y., Cho, Hwa Jin and Fraser, John F. (2021). The use of extracorporeal membrane oxygenation in children with acute fulminant myocarditis. Clinical and Experimental Pediatrics, 64 (5), 188-195. doi: 10.3345/cep.2020.00836

The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit

Passmore, Margaret R., Ki, Katrina K., Chan, Chris H. H., Lee, Talvin, Bouquet, Mahé, Wood, Emily S., Raman, Sainath, Rozencwajg, Sacha, Burrell, Aidan J. C., McDonald, Charles I., Langguth, Daman, Shekar, Kiran, Malfertheiner, Maximilian V., Fraser, John F. and Suen, Jacky Y. (2020). The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit. Artificial Organs, 44 (12) aor.13771, 1276-1285. doi: 10.1111/aor.13771

Predicting neurological recovery following traumatic brain injury in children: a systematic review of prognostic models

Huth, Samuel Fergus, Slater, Anthony, Waak, Michaela, Barlow, Karen Maria and Raman, Sainath (2020). Predicting neurological recovery following traumatic brain injury in children: a systematic review of prognostic models. Journal of Neurotrauma, 37 (20) neu.2020.7158, 2141-2149. doi: 10.1089/neu.2020.7158

Prediction of Acute Kidney Injury on Admission to Pediatric Intensive Care

Raman, Sainath, Tai, Chian Wern, Le Marsney, Renate, Schibler, Andreas, Gibbons, Kristen and Schlapbach, Luregn J. (2020). Prediction of Acute Kidney Injury on Admission to Pediatric Intensive Care. Pediatric Critical Care Medicine, Publish Ahead of Print (9), 811-819. doi: 10.1097/pcc.0000000000002411

Catheterisation of the brachial artery in children: should we be so concerned?

Hussey, Alexander and Raman, Sainath (2020). Catheterisation of the brachial artery in children: should we be so concerned?. Critical Care and Resuscitation, 22 (2), 173-173. doi: 10.51893/2020.2.l2

Endotracheal intubation by a specialised paediatric retrieval team

Glasheen, John, Holmes, Paul, Rampersad, Neeta and Raman, Sainath (2020). Endotracheal intubation by a specialised paediatric retrieval team. Emergency Medicine Australasia, 32 (1), 75-79. doi: 10.1111/1742-6723.13341

A dedicated paediatric logistic organ dysfunction score - adjusted pressure injury risk assessment scale is required for tertiary paediatric ICUs

Crane, Natalie, Pool, Natasha, Chang, Ivy, Rogan, Sharna, Stocker, Christian and Raman, Sainath (2019). A dedicated paediatric logistic organ dysfunction score - adjusted pressure injury risk assessment scale is required for tertiary paediatric ICUs. Cardiology in the Young, 29 (3), 455-456. doi: 10.1017/s1047951118002251

Widening Evidence-Base of Risk With Hyperoxia

Raman, Sainath, Ray, Samiran and Peters, Mark J. (2019). Widening Evidence-Base of Risk With Hyperoxia. Pediatric Critical Care Medicine, 20 (1), 99-99. doi: 10.1097/PCC.0000000000001770

Near infrared spectroscopy with a vascular occlusion test as a biomarker in children with mitochondrial and other neuro-genetic disorders

Raman, Sainath, Chentouf, Latifa, DeVile, Catherine, Peters, Mark J. and Rahman, Shamima (2018). Near infrared spectroscopy with a vascular occlusion test as a biomarker in children with mitochondrial and other neuro-genetic disorders. PLoS One, 13 (7) e0199756, e0199756. doi: 10.1371/journal.pone.0199756

Protocol for a randomised pilot multiple centre trial of conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU)

Jones, Gareth A. L., Ramnarayan, Padmanabhan, Raman, Sainath, Inwald, David, Grocott, Michael P. W., Eaton, Simon, Ray, Samiran, Griksaitis, Michael J., Pappachan, John, Wiley, Daisy, Mouncey, Paul R., Wulff, Jerome, Harrison, David A., Rowan, Kathryn M. and Peters, Mark J. (2017). Protocol for a randomised pilot multiple centre trial of conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU). BMJ Open, 7 (12) e019253, e019253. doi: 10.1136/bmjopen-2017-019253

Haemodynamic changes with paracetamol in critically-ill children

Ray, Samiran, Brick, Thomas, Raman, Sainath, Birrell, Paul J., Klein, Nigel J. and Peters, Mark J. (2017). Haemodynamic changes with paracetamol in critically-ill children. Journal of Critical Care, 40, 108-112. doi: 10.1016/j.jcrc.2017.03.026

Pao(2)/Fio(2) ratio derived from the Spo(2)/Fio(2) ratio to improve mortality prediction using the Pediatric Index of Mortality-3 score in transported intensive care admissions

Ray, Samiran, Rogers, Libby, Pagel, Christina, Raman, Sainath, Peters, Mark J. and Ramnarayan, Padmanabhan (2017). Pao(2)/Fio(2) ratio derived from the Spo(2)/Fio(2) ratio to improve mortality prediction using the Pediatric Index of Mortality-3 score in transported intensive care admissions. Pediatric Critical Care Medicine, 18 (3), E131-E136. doi: 10.1097/pcc.0000000000001075

Liberal oxygenation in paediatric intensive care: retrospective analysis of high-resolution SpO2 data

Ray, Samiran, Rogers, L., Raman, S. and Peters, M. J. (2017). Liberal oxygenation in paediatric intensive care: retrospective analysis of high-resolution SpO2 data. Intensive Care Medicine, 43 (1), 146-147. doi: 10.1007/s00134-016-4606-y

Admission Pao(2) and mortality in critically ill children: a cohort study and systematic review

Raman, Sainath, Prince, Nicholas J., Hoskote, Aparna, Ray, Samiran and Peters, Mark J. (2016). Admission Pao(2) and mortality in critically ill children: a cohort study and systematic review. Pediatric Critical Care Medicine, 17 (10), E444-E450. doi: 10.1097/pcc.0000000000000905

Incidence of hypermanganesemia in children who are administered parenteral nutrition

Greene, Edel, Shokur, Rumeena, Brown, Lisa, Petros, Andy and Raman, Sainath (2016). Incidence of hypermanganesemia in children who are administered parenteral nutrition. Journal of Parenteral and Enteral Nutrition, 40 (6), 766-767. doi: 10.1177/0148607116638046

Survey of oxygen delivery practices in UK paediatric intensive care units

Raman, Sainath, Ray, Samiran and Peters, Mark J. (2016). Survey of oxygen delivery practices in UK paediatric intensive care units. Critical Care Research and Practice, 2016 6312970, 6312970-4. doi: 10.1155/2016/6312970

Oxidative phosphorylation gene expression falls at onset and throughout the development of meningococcal sepsis-induced multi-organ failure in children

Raman, Sainath, Klein, Nigel, Kwan, Antonia, Hubank, Mike, Rahman, Shamima, Rashid, Asrar and Peters, Mark J. (2015). Oxidative phosphorylation gene expression falls at onset and throughout the development of meningococcal sepsis-induced multi-organ failure in children. Intensive Care Medicine, 41 (8), 1489-1490. doi: 10.1007/s00134-015-3817-y

Impact of stops for road traffic accidents on the inter-hospital transport of critically ill children

Raman, Sainath and Ramnarayan, Padmanabhan (2014). Impact of stops for road traffic accidents on the inter-hospital transport of critically ill children. Emergency Medicine Journal, 31 (7), 589-590. doi: 10.1136/emermed-2013-202462

Fluid management in the critically ill child

Raman, Sainath and Peters, Mark J. (2014). Fluid management in the critically ill child. Pediatric Nephrology, 29 (1), 23-34. doi: 10.1007/s00467-013-2412-0

Application of a clinical transfusion score to pediatric cardiac surgical patients

Raman, Sainath, Desai, Ajay and Halley, Gillian (2009). Application of a clinical transfusion score to pediatric cardiac surgical patients. Pediatric Critical Care Medicine, 10 (6), 701-701. doi: 10.1097/pcc.0b013e3181b7f920

Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department

Gilholm, P., Irwin, A., Lister, P., Harley, A., Raman, S., Schlapbach, L. J. and Gibbons, K. (2022). Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department. 11th Congress of the World Federation of Pediatric Intensive & Critical Care Societies, Online, 12-16 July 2022. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000899876.46317.ec