Dr Vanessa Bonazzi

Research Fellow

The University of Queensland Diamantina Institute
Faculty of Medicine
v.bonazzi@uq.edu.au
+61 7 344 38025

Overview

Qualifications

  • PhD, Paris VII

Publications

View all Publications

Publications

Book Chapter

Journal Article

  • Oo, Zay Yar, Proctor, Martina, Stevenson, Alexander J., Nazareth, Deborah, Fernando, Madushan, Daignault, Sheena M., Lanagan, Catherine, Walpole, Sebastian, Bonazzi, Vanessa, ┼ákalamera, Dubravka, Snell, Cameron, Haass, Nikolas K., Larsen, Jill E. and Gabrielli, Brian (2019) Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine. Molecular Oncology, 13 7: 1503-1518. doi:10.1002/1878-0261.12497

  • Newell, Felicity, Patel, Kalpana, Gartside, Michael, Krause, Lutz, Brosda, Sandra, Aoude, Lauren G., Loffler, Kelly A., Bonazzi, Vanessa F., Patch, Ann-Marie, Kazakoff, Stephen H., Holmes, Oliver, Xu, Qinying, Wood, Scott, Leonard, Conrad, Lampe, Guy, Lord, Reginald V., Whiteman, David C., Pearson, John V., Nones, Katia, Waddell, Nicola and Barbour, Andrew P. (2019) Complex structural rearrangements are present in high-grade dysplastic Barrett's oesophagus samples. BMC Medical Genomics, 12 1: . doi:10.1186/s12920-019-0476-9

  • Packer, Leisl M, Stehbens, Samantha J, Bonazzi, Vanessa F, Gunter, Jennifer H, Ju, Robert J, Ward, Micheal, Gartside, Michael G, Byron, Sara A and Pollock, Pamela M (2018) Bcl-2 inhibitors enhance FGFR inhibitor-induced mitochondrial-dependent cell death in FGFR2-mutant endometrial cancer. Molecular Oncology, . doi:10.1002/1878-0261.12422

  • Packer, Leisl M., Geng, Xinyan, Bonazzi, Vanessa F., Ju, Robert J., Mahon, Clare E., Cummings, Margaret C., Stephenson, Sally-Anne and Pollock, Pamela M. (2017) PI3K inhibitors synergize with FGFR inhibitors to enhance antitumor responses in FGFR2mutant endometrial cancers. Molecular Cancer Therapeutics, 16 4: 637-648. doi:10.1158/1535-7163.MCT-16-0415

  • Stark, Mitchell S., Tom, Lisa N., Boyle, Glen M., Bonazzi, Vanessa F., Soyer, H. Peter, Herington, Adrian C., Pollock, Pamela M. and Hayward, Nicholas K. (2016) The 'Melanoma-enriched' microRNA miR-4731-5p acts as a tumour suppressor. Oncotarget, 7 31: 49677-49687. doi:10.18632/oncotarget.10109

  • Stark, Mitchell S., Bonazzi, Vanessa F., Boyle, Glen M., Palmer, Jane M., Symmons, Judith, Lanagan, Catherine M., Schmidt, Christopher W., Herington, Adrian C., Ballotti, Robert, Pollock, Pamela M. and Hayward, Nicholas K. (2015) miR-514a regulates the tumour suppressor NF1 and modulates BRAFi sensitivity in melanoma. Oncotarget, 6 19: 17753-17763. doi:10.18632/oncotarget.3924

  • Aoude, Lauren G., Pritchard, Antonia L., Robles-Espinoza, Carla Daniela, Wadt, Karin, Harland, Mark, Choi, Jiyeon, Gartside, Michael, Quesada, Victor, Johansson, Peter, Palmer, Jane M., Ramsay, Andrew J., Zhang, Xijun, Jones, Kristine, Symmons, Judith, Holland, Elizabeth A., Schmid, Helen, Bonazzi, Vanessa, Woods, Susan, Dutton-Regester, Ken, Stark, Mitchell S., Snowden, Helen, van Doom, Remco, Montgomery, Grant W., Martin, Nicholas G., Keane, Thomas M., Lopez-Otin, Carlos, Gerdes, Anne-Marie, Olsson, Hakan, Ingvar, Christian, Borg, Ake, Gruis, Nelleke A., Trent, Jeffrey M., Jonsson, Goran, Bishop, D. Timothy, Mann, Graham J., Newton-Bishop, Julia A., Brown, Kevin M., Adams, David J. and Hayward, Nicholas K. (2015) Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma. Journal of the National Cancer Institute, 107 2: 1-7. doi:10.1093/jnci/dju408

  • Cheli, Yann, Bonnazi, Vanessa F., Jacquel, Arnaud, Allegra, Maryline, De Donatis, Gian Marco, Bahadoran, Philippe, Bertolotto, Corine and Ballotti, Robert (2014) CD271 is an imperfect marker for melanoma initiating cells. Oncotarget, 5 14: . doi:10.18632/oncotarget.1967

  • Ohanna, Mickaël, Cheli, Yann, Bonet, Caroline, Bonazzi, Vanessa F, Allegra, Marylin, Giuliano, Sandy, Bille, Karine, Bahadoran, Philippe, Giacchero, Damien, Lacour, Jean Philippe, Boyle, Glen M, Hayward, Nicholas F, Bertolotto, Corine and Ballotti, Robert (2014) Secretome from senescent melanoma engages the STAT3 pathway to favor reprogramming of naive melanoma towards a tumor-initiating cell phenotype. Oncotarget, 4 12: . doi:10.18632/oncotarget.1143

  • Bonazzi, Vanessa F., Stark, Mitchell S. and Hayward, Nicholas K. (2012) MicroRNA regulation of melanoma progression. Melanoma Research, 22 2: 101-113. doi:10.1097/CMR.0b013e32834f6fbb

  • Stark, Mitchell S., Woods, Susan L., Gartside, Michael G., Bonazzi, Vanessa F., Dutton-Regester, Ken, Aoude, Lauren G., Chow, Donald, Sereduk, Chris, Niemi, Natalie M., Tang, Nanyun, Ellis, Jonathan J., Reid, Jeffrey, Zismann, Victoria, Tyagi, Sonika, Muzny, Donna, Newsham, Irene, Wu, YuanQing, Palmer, Jane M., Pollak, Thomas, Youngkin, David, Brooks, Bradford R., Lanagan, Catherine, Schmidt, Christopher W., Kobe, Bostjan, MacKeigan, Jeffrey P., Yin, Hongwei, Brown, Kevin M., Gibbs, Richard, Trent, Jeffrey and Hayward, Nicholas K. (2012) Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing. Nature Genetics, 44 2: 165-169. doi:10.1038/ng.1041

  • Yokoyama, Satoru, Woods, Susan L., Boyle, Glen M., Aoude, Lauren G., MacGregor, Stuart, Zismann, Victoria, Gartside, Michael, Cust, Anne E., Haq, Rizwan, Harland, Mark, Taylor, John C., Duffy, David L., Holohan, Kelly, Dutton-Regester, Ken, Palmer, Jane M., Bonazzi, Vanessa, Stark, Mitchell S., Symmons, Judith, Law, Matthew H., Schmidt, Christopher, Lanagan, Cathy, O'Connor, Linda, Holland, Elizabeth A., Schmid, Helen, Maskiell, Judith A., Jetann, Jodie, Ferguson, Megan, Jenkins, Mark A., Kefford, Richard F., Giles, Graham G., Armstrong, Bruce K., Aitken, Joanne F., Hopper, John L., Whiteman, David C., Pharoah, Paul D., Easton, Douglas F., Dunning, Alison M., Newton-Bishop, Julia A., Montgomery, Grant W., Martin, Nicholas G., Mann, Graham J., Bishop, D. Timothy, Tsao, Hensin, Trent, Jeffrey M., Fisher, David E., Hayward, Nicholas K. and Brown, Kevin M. (2011) A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature, 480 7375: 99-103. doi:10.1038/nature10630

  • Bonazzi, Vanessa F., Nancarrow, Derek J., Stark, Mitchell S., Moser, Ralf J., Boyle, Glen M., Aoude, Lauren G., Schmidt, Christopher and Hayward, Nicholas K. (2011) Cross-platform array screening identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as genes frequently silenced by methylation in melanoma. PLoS One, 6 10: 1-9. doi:10.1371/journal.pone.0026121

  • Boyle, Glen M., Woods, Susan L., Bonazzi, Vanessa F., Stark, Mitchell S., Hacker, Elke, Aoude, Lauren G., Dutton-Regester, Ken, Cook, Anthony L., Sturm, Richard A. and Hayward, Nicholas K. (2011) Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor. Pigment Cell and Melanoma Research, 24 3: 525-537. doi:10.1111/j.1755-148X.2011.00849.x

  • Dry, Jonathan R., Pavey, Sandra, Pratilas, Christine A., Harbron, Chris, Runswick, Sarah, Hodgson, Darren, Chresta, Christine, McCormack, Rose, Byrne, Natalie, Cockerill, Mark, Graham, Alexander, Beran, Garry, Cassidy, Andrew, Haggerty, Carolyn, Brown, Helen, Ellison, Gillian, Dering, Judy, Taylor, Barry S., Stark, Mitchell, Bonazzi, Vanessa, Ravishankar, Sugandha, Packer, Leisl, Xing, Feng, Solit, David B., Finn, Richard S., Rosen, Neal, Hayward, Nicholas K., French, Tim and Smith, Paul D. (2010) Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244). Cancer Research, 70 6: 2264-2273. doi:10.1158/0008-5472.CAN-09-1577

  • Kuphal, Silke, Martyn, Adam C., Pedley, Julie, Crowther, Lisa M., Bonazzi, Vanessa F., Parsons, Peter G., Bosserhoff, Anja K., Hayward, Nicholas K. and Boyle, Glen M. (2009) H-Cadherin expression reduces invasion of malignant melanoma. Pigment Cell and Melanoma Research, 22 3: 296-306. doi:10.1111/j.1755-148X.2009.00568.x

  • Bonazzi, V.F., Irwin, D.L and Hayward, N (2009) Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma. Genes, Chromosomes & Cancer, 48 1: 10-21. doi:10.1002/gcc.20615

  • Bonazzi, Vanessa, Medjkane, Souhila, Quignon, Frédérique and Delattre, Olivier (2005) Complementation analyses suggest species-specific functions of the SNF5 homology domain. Biochemical and Biophysical Research Communications, 336 2: 634-638. doi:10.1016/j.bbrc.2005.08.133