The University of Queensland

Genetic impact of blood C-reactive protein levels on chronic spinal & widespread pain

Farrell, Scott F., Sterling, Michele, Klyne, David M., Mustafa, Sanam, Campos, Adrián I., Kho, Pik-Fang, Lundberg, Mischa, Rentería, Miguel E., Ngo, Trung Thanh and Cuéllar-Partida, Gabriel (2023). Genetic impact of blood C-reactive protein levels on chronic spinal & widespread pain. European Spine Journal, 1-8. doi: 10.1007/s00586-023-07711-7

How do nonsurgical interventions improve pain and physical function in people with osteoarthritis? A scoping review of mediation analysis studies

Lima, Yuri Lopes, Lee, Hopin, Klyne, David M., Dobson, Fiona L., Hinman, Rana S., Bennell, Kim L. and Hall, Michelle (2023). How do nonsurgical interventions improve pain and physical function in people with osteoarthritis? A scoping review of mediation analysis studies. Arthritis Care and Research, 75 (3), 467-481. doi: 10.1002/acr.24983

Neurobiology Of Osteoarthritis - A Systematic Review And Activation Likelihood Estimation Meta-Analysis

Hall, M., Dobson, F., Klyne, D., Zheng, C., Lima, Y. and Egorova-Brumley, N. (2023). Neurobiology Of Osteoarthritis - A Systematic Review And Activation Likelihood Estimation Meta-Analysis. Osteoarthritis and Cartilage, 31, S380. doi: 10.1016/j.joca.2023.01.431

Pain-related cognitions and emotional distress are not associated with conditioned pain modulation: an explorative analysis of 1142 participants with acute, subacute, and chronic pain

Plinsinga, Melanie Louise, Vuvan, Viana, Maclachlan, Liam, Klyne, David, Graven-Nielsen, Thomas, Vicenzino, Bill, Hodges, Paul and Bjarke Vaegter, Henrik (2023). Pain-related cognitions and emotional distress are not associated with conditioned pain modulation: an explorative analysis of 1142 participants with acute, subacute, and chronic pain. Pain. doi: 10.1097/j.pain.0000000000002864

Effects of adding aerobic physical activity to strengthening exercise on hip osteoarthritis symptoms: protocol for the PHOENIX randomised controlled trial

Hall, Michelle, Allison, Kim, Hinman, Rana S., Bennell, Kim L., Spiers, Libby, Knox, Gabrielle, Plinsinga, Melanie, Klyne, David M., McManus, Fiona, Lamb, Karen E., Da Costa, Ricardo, Murphy, Nicholas J. and Dobson, Fiona L. (2022). Effects of adding aerobic physical activity to strengthening exercise on hip osteoarthritis symptoms: protocol for the PHOENIX randomised controlled trial. BMC Musculoskeletal Disorders, 23 (1) 361. doi: 10.1186/s12891-022-05282-0

Balance control in unstable sitting in individuals with an acute episode of low back pain

van den Hoorn, Wolbert, Meroni, Roberto, Klyne, David M., Alshehri, Mansour Abdullah and Hodges, Paul W. (2022). Balance control in unstable sitting in individuals with an acute episode of low back pain. Gait and Posture, 95, 15-21. doi: 10.1016/j.gaitpost.2022.03.014

Postural control of the trunk in individuals with and without low back pain during unstable sitting: A protocol for a systematic review with an individual participant data meta-analysis

Alshehri, Mansour Abdullah, van den Hoorn, Wolbert, Klyne, David M. and Hodges, Paul W. (2022). Postural control of the trunk in individuals with and without low back pain during unstable sitting: A protocol for a systematic review with an individual participant data meta-analysis. PLoS One, 17 (5) e0268381, 1-14. doi: 10.1371/journal.pone.0268381

Risk factors for low back pain outcome: Does it matter when they are measured?

Klyne, David Murray, Hall, Leanne Marie, Nicholas, Michael K. and Hodges, Paul William (2022). Risk factors for low back pain outcome: Does it matter when they are measured?. European Journal of Pain, 26 (4), 835-854. doi: 10.1002/ejp.1911

Relationship between systemic inflammation and recovery over 12 months after an acute episode of low back pain

Klyne, David M., Barbe, Mary F. and Hodges, Paul W. (2022). Relationship between systemic inflammation and recovery over 12 months after an acute episode of low back pain. The Spine Journal, 22 (2), 214-225. doi: 10.1016/j.spinee.2021.09.006

Does the interaction between local and systemic inflammation provide a link from psychology and lifestyle to tissue health in musculoskeletal conditions?

Klyne, David M., Barbe, Mary F., James, Greg and Hodges, Paul W. (2021). Does the interaction between local and systemic inflammation provide a link from psychology and lifestyle to tissue health in musculoskeletal conditions?. International Journal of Molecular Sciences, 22 (14) 7299, 1-21. doi: 10.3390/ijms22147299

Coordination of hip and spine to maintain equilibrium in unstable sitting revealed by spectral analysis

Alshehri, Mansour Abdullah, van den Hoorn, Wolbert, Klyne, David M. and Hodges, Paul W. (2021). Coordination of hip and spine to maintain equilibrium in unstable sitting revealed by spectral analysis. Journal of Neurophysiology, 125 (5), 1814-1824. doi: 10.1152/jn.00555.2020

Cohort profile: why do people keep hurting their back?

Klyne, David M., van den Hoorn, Wolbert, Barbe, Mary F., Cholewicki, Jacek, M. Hall, Leanne, Khan, Asaduzzaman, Meroni, Roberto, Moseley, G. Lorimer, Nicholas, Michael, O’Sullivan, Lee, Park, Rachel, Russell, Glen, Sterling, Michele and Hodges, Paul W. (2020). Cohort profile: why do people keep hurting their back?. BMC Research Notes, 13 (1) 538, 538. doi: 10.1186/s13104-020-05356-z

Trunk stiffness decreases and trunk damping increases with experimental low back pain

van den Hoorn, Wolbert, Cholewicki, Jacek, Coppieters, Michel W., Klyne, David M. and Hodges, Paul W. (2020). Trunk stiffness decreases and trunk damping increases with experimental low back pain. Journal of Biomechanics, 112 110053, 110053. doi: 10.1016/j.jbiomech.2020.110053

Blocking CTGF/CCN2 reverses neural fibrosis and sensorimotor declines in a rat model of overuse-induced median mononeuropathy

Barbe, Mary F., Hilliard, Brendan A., Amin, Mamta, Harris, Michele Y., Hobson, Lucas J., Cruz, Geneva E., Dorotan, Jocelynne T., Paul, Ryan W., Klyne, David M. and Popoff, Steven N. (2020). Blocking CTGF/CCN2 reverses neural fibrosis and sensorimotor declines in a rat model of overuse-induced median mononeuropathy. Journal of Orthopaedic Research, 38 (11) jor.24709, 2396-2408. doi: 10.1002/jor.24709

Circulating adipokines in predicting the transition from acute to persistent low back pain

Klyne, David M. and Hodges, Paul W. (2020). Circulating adipokines in predicting the transition from acute to persistent low back pain. Pain Medicine, 21 (11), 2975-2985. doi: 10.1093/pm/pnaa052

Forced treadmill running reduces systemic inflammation yet worsens upper limb discomfort in a rat model of work-related musculoskeletal disorders

Smith, Tianqi Tenchi Gao, Barr-Gillespie, Ann E, Klyne, David M, Harris, Michelle Y, Amin, Mamta, Paul, Ryan W, Cruz, Geneva E, Zhao, Huaqing, Gallagher, Sean and Barbe, Mary F (2020). Forced treadmill running reduces systemic inflammation yet worsens upper limb discomfort in a rat model of work-related musculoskeletal disorders. BMC Musculoskeletal Disorders, 21 (1) 57, 57. doi: 10.1186/s12891-020-3085-z

Letter to the editor concerning “Multiple confounders influence the association between low-grade systemic inflammation and musculoskeletal pain. A call for a prudent interpretation of the literature” by Schipholt et al

Klyne, David M. and Hodges, Paul W. (2019). Letter to the editor concerning “Multiple confounders influence the association between low-grade systemic inflammation and musculoskeletal pain. A call for a prudent interpretation of the literature” by Schipholt et al. Spine Journal, 19 (11), 1899-1900. doi: 10.1016/j.spinee.2019.06.011

Are signs of central sensitisation in acute low back pain a precursor to poor outcome?

Klyne, David M., Moseley, G. Lorimer, Sterling, Michele, Barbe, Mary F. and Hodges, Paul W. (2019). Are signs of central sensitisation in acute low back pain a precursor to poor outcome?. The Journal of Pain, 20 (8), 994-1009. doi: 10.1016/j.jpain.2019.03.001

ISSLS Prize in Basic science 2019: physical activity attenuates fibrotic alterations to the multifidus muscle associated with intervertebral disc degeneration

James, G., Klyne, D. M., Millecamps, M., Stone, L. S. and Hodges, P. W. (2019). ISSLS Prize in Basic science 2019: physical activity attenuates fibrotic alterations to the multifidus muscle associated with intervertebral disc degeneration. European Spine Journal, 28 (5), 893-904. doi: 10.1007/s00586-019-05902-9

Individual variation in pain sensitivity and conditioned pain modulation in acute low back pain: impact of stimulus type, sleep, psychological and lifestyle factors

Klyne, David M., Moseley, G. Lorimer, Sterling, Michele, Barbe, Mary F. and Hodges, Paul W. (2018). Individual variation in pain sensitivity and conditioned pain modulation in acute low back pain: impact of stimulus type, sleep, psychological and lifestyle factors. The Journal of Pain, 19 (8), 942.e1-942.e18. doi: 10.1016/j.jpain.2018.02.017

ISSLS Prize in clinical science 2018: Longitudinal analysis of inflammatory, psychological, and sleep-related factors following an acute low back pain episode-the good, the bad, and the ugly

Klyne, David M., Barbe, Mary F, van den Hoorn, Wolbert and Hodges, Paul W. (2018). ISSLS Prize in clinical science 2018: Longitudinal analysis of inflammatory, psychological, and sleep-related factors following an acute low back pain episode-the good, the bad, and the ugly. European Spine Journal, 27 (4), 763-777. doi: 10.1007/s00586-018-5490-7

Systemic inflammatory profiles and their relationships with demographic, behavioural and clinical features in acute low back pain

Klyne, David M., Barbe, Mary F. and Hodges, Paul W. (2017). Systemic inflammatory profiles and their relationships with demographic, behavioural and clinical features in acute low back pain. Brain, Behavior, and Immunity, 60, 84-92. doi: 10.1016/j.bbi.2016.10.003

Effect of types and anatomical arrangement of painful stimuli on conditioned pain modulation

Klyne, David M., Schmid, Annina B., Moseley, G. Lorimer, Sterling, Michele and Hodges Paul W. (2015). Effect of types and anatomical arrangement of painful stimuli on conditioned pain modulation. Journal of Pain, 16 (2), 176-185. doi: 10.1016/j.jpain.2014.11.005

The effect of anterior cruciate ligament rupture on the timing and amplitude of gastrocnemius muscle activation: A study of alterations in EMG measures and their relationship to knee joint stability

Klyne, David M., Keays, Susan L., Bullock-Saxton, Joanne E. and Newcombe, Peter A. (2012). The effect of anterior cruciate ligament rupture on the timing and amplitude of gastrocnemius muscle activation: A study of alterations in EMG measures and their relationship to knee joint stability. Journal of Electromyography and Kinesiology, 22 (3), 446-455. doi: 10.1016/j.jelekin.2012.01.013

Uncovering the role of sleep and exercise in the transition from acute to persistent pain

Klyne, D.M., Hilliard, B., Harris, M., Amin, M., Testa, C., Hobson, L., Cruz, G., Hodges, P.W. and Barbe, M.F. (2021). Uncovering the role of sleep and exercise in the transition from acute to persistent pain. Psychoneuroimmunology Research Society's 27th Annual Meeting, Online, 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.bbi.2021.08.099

Longitudinal analysis of inflammatory, psychological, and sleep-related factors following an acute low back pain episode—the good, the bad, and the ugly

Klyne, D. M. (2019). Longitudinal analysis of inflammatory, psychological, and sleep-related factors following an acute low back pain episode—the good, the bad, and the ugly. PsychoNeuroImmunology Research Society's 25th Annual Scientific Meeting, Miami Beach, FL, United States, 6-9 June 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.bbi.2018.11.244

Longitudinal analysis of inflammatory, psychological, and sleep-related factors following an acute low back pain episode: a potential factor in tissue effects in low back pain

Klyne, David, Barbe, Mary, Van Den Hoorn, Wolbert and Hodges, Paul (2018). Longitudinal analysis of inflammatory, psychological, and sleep-related factors following an acute low back pain episode: a potential factor in tissue effects in low back pain. 5th International Fascia Research Congress, Berlin, Germany, 14-15 November 2018. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jbmt.2018.09.056

Supplemental Data for "Coordination of hip and spine to maintain equilibrium in unstable sitting revealed by spectral analysis" paper

Alshehri, Mansour Abdullah , van den Hoorn, Wolbert, Klyne, David M. and Hodges, Paul W. (2021). Supplemental Data for "Coordination of hip and spine to maintain equilibrium in unstable sitting revealed by spectral analysis" paper. The University of Queensland. (Dataset) doi: 10.14264/c3f49b3

Biological factors in the transition from acute to persistent low back pain

Klyne, David Murray (2018). Biological factors in the transition from acute to persistent low back pain. PhD Thesis, School of Health and Rehabilitation Sciences, The University of Queensland. doi: 10.14264/uql.2018.468