The University of Queensland

Group A streptococcal vaccine candidates: potential for the development of a human vaccine

Henningham, Anna, Gillen, Christine M. and Walker, Mark J. (2013). Group A streptococcal vaccine candidates: potential for the development of a human vaccine. Host-pathogen interactions in streptococcal diseases. (pp. 207-242) edited by G. Singh Chhatwal. New York, NY, United States: Springer. doi: 10.1007/82_2012_284

A systematic review of the clinical impact of small colony variants in patients with cystic fibrosis

Ryan, Harrigan, Ballard, Emma, Stockwell, Rebecca E., Duplancic, Christine, Thomson, Rachel M., Smith, Kimberley and Bell, Scott C. (2023). A systematic review of the clinical impact of small colony variants in patients with cystic fibrosis. BMC Pulmonary Medicine, 23 (1) 323, 1-10. doi: 10.1186/s12890-023-02611-4

Emergence and impact of oprD mutations in Pseudomonas aeruginosa strains in cystic fibrosis

Sherrard, Laura J., Wee, Bryan A., Duplancic, Christine, Ramsay, Kay A., Dave, Keyur A., Ballard, Emma, Wainwright, Claire E., Grimwood, Keith, Sidjabat, Hanna E., Whiley, David M., Beatson, Scott A., Kidd, Timothy J. and Bell, Scott C. (2021). Emergence and impact of oprD mutations in Pseudomonas aeruginosa strains in cystic fibrosis. Journal of Cystic Fibrosis, 21 (1), e35-e43. doi: 10.1016/j.jcf.2021.03.007

All major cholesterol-dependent cytolysins use glycans as cellular receptors

Shewell, Lucy K., Day, Christopher J., Jen, Freda E.-C., Haselhorst, Thomas, Atack, John M., Reijneveld, Josephine F., Everest-Dass, Arun, James, David B. A., Boguslawski, Kristina M., Brouwer, Stephan, Gillen, Christine M., Luo, Zhenyao, Kobe, Bostjan, Nizet, Victor, von Itzstein, Mark, Walker, Mark J., Paton, Adrienne W., Paton, James C., Torres, Victor J. and Jennings, Michael P. (2020). All major cholesterol-dependent cytolysins use glycans as cellular receptors. Science Advances, 6 (21) EAAZ4926, eaaz4926. doi: 10.1126/sciadv.aaz4926

Multi-centre ethics and research governance review can impede non-interventional clinical research

Duplancic, Christine, Crough, Tania, Bell, Scott C., Australian NTM in CF Study Group and Thomson, Rachel (2019). Multi-centre ethics and research governance review can impede non-interventional clinical research. Internal Medicine Journal, 49 (6), 722-728. doi: 10.1111/imj.14158

A controlled human infection model of Group A Streptococcus pharyngitis: which strain and why?

Osowicki, Joshua, Azzopardi, Kristy I., McIntyre, Liam, Rivera-Hernandez, Tania, Ong, Cheryl-Lynn Y., Baker, Ciara, Gillen, Christine M., Walker, Mark J., Smeesters, Pierre R., Davies, Mark R. and Steer, Andrew C. (2019). A controlled human infection model of Group A Streptococcus pharyngitis: which strain and why?. mSphere, 4 (1) e00647-18, e00647-18. doi: 10.1128/mSphere.00647-18

Face Masks Reduce the Release of Pseudomonas aeruginosa Cough Aerosols when Worn for Clinically-Relevant Time Periods

Stockwell, Rebecca E., Wood, Michelle E., He, Congrong, Sherrard, Laura J., Ballard, Emma L., Kidd, Timothy J., Johnson, Graham R., Knibbs, Luke D., Morawska, Lidia, Bell, Scott C., CF Cough Aerosol Group and Duplancic, Christine (2018). Face Masks Reduce the Release of Pseudomonas aeruginosa Cough Aerosols when Worn for Clinically-Relevant Time Periods. American Journal of Respiratory and Critical Care Medicine, 198 (10) rccm.201805-0823LE, 1339-1342. doi: 10.1164/rccm.201805-0823LE

Linoleic and palmitoleic acid block streptokinase-mediated plasminogen activation and reduce severity of invasive group A streptococcal infection

Rox, Katharina, Jansen, Rolf, Loof, Torsten G., Gillen, Christine M., Bernecker, Steffen, Walker, Mark J., Chhatwal, Gursharan Singh and Müller, Rolf (2017). Linoleic and palmitoleic acid block streptokinase-mediated plasminogen activation and reduce severity of invasive group A streptococcal infection. Scientific Reports, 7 (1) 11798, 1-12. doi: 10.1038/s41598-017-11276-z

Streptococcus iniae cpsG alters capsular carbohydrate composition and is a cause of serotype switching in vaccinated fish

Heath, Candice, Gillen, Christine M., Chrysanthopoulos, Panagiotis, Walker, Mark J. and Barnes, Andrew C. (2016). Streptococcus iniae cpsG alters capsular carbohydrate composition and is a cause of serotype switching in vaccinated fish. Veterinary Microbiology, 193, 116-124. doi: 10.1016/j.vetmic.2016.08.011

Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models

Rivera-Hernandez, Tania, Pandey, Manisha, Henningham, Anna, Cole, Jason, Choudhury, Biswa, Cork, Amanda J., Gillen, Christine M., Ghaffar, Khairunnisa Abdul, West, Nicholas P., Silvestri, Guido, Good, Michael F., Moyle, Peter M., Toth, Istvan, Nizet, Victor, Batzloff, Michael R. and Walker, Mark J. (2016). Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models. mBio, 7 (3) e00618-16, e00618-16.1-e00618-16.9. doi: 10.1128/mBio.00618-16

Manganese homeostasis in group A Streptococcus is critical for resistance to oxidative stress and virulence

Turner, Andrew G., Ong, Cheryl-lynn, Gillen, Christine M., Davies, Mark R., West, Nicholas P., McEwan, Alastair G. and Walker, Mark J. (2015). Manganese homeostasis in group A Streptococcus is critical for resistance to oxidative stress and virulence. mBio, 6 (2) e00278-15, 1-10. doi: 10.1128/mBio.00278-15

The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity.

Shewell, Lucy K., Harvey,Richard M., Higgins, Melanie A., Day, Christopher J., Hartley-Tassell, Lauren E., Chen, Austen Y., Gillen, Christine M., James, David B. A., Alonzo, Francis, Torres, Victor J., Walker, Mark J., Paton, Adrienne W., Paton, James C. and Jennings, Michael P. (2014). The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity.. Proceedings of the National Academy of Sciences of the United State of America, 111 (49), E5312-E5320. doi: 10.1073/pnas.1412703111

An antimicrobial role for zinc in innate immune defence against group A streptococcus

Ong, Cheryl-lynn Y., Gillen, Christine M., Barnett, Timothy C., Walker, Mark J. and McEwan, Alastair G. (2014). An antimicrobial role for zinc in innate immune defence against group A streptococcus. Journal of Infectious Diseases, 209 (10), 1500-1508. doi: 10.1093/infdis/jiu053

Disease manifestations and pathogenic mechanisms of group A Streptococcus

Walker, Mark J., Barnett, Timothy C., McArthur, Jason D., Cole, Jason N., Gillen, Christine M., Henningham, Anna, Sriprakash, K. S., Sanderson-Smith, Martina L. and Nizet, Victor (2014). Disease manifestations and pathogenic mechanisms of group A Streptococcus. Clinical Microbiology Reviews, 27 (2), 264-301. doi: 10.1128/CMR.00101-13

The globally disseminated M1T1 clone of Group A Streptococcus evades autophagy for intracellular replication

Barnett, Timothy C., Liebl, David, Seymour, Lisa M., Gillen, Christine M., Lim, Jin Yan, LaRock, Christopher N., Davies, Mark R., Schulz, Benjamin L., Nizet, Victor, Teasdale, Rohan D. and Walker, Mark J. (2013). The globally disseminated M1T1 clone of Group A Streptococcus evades autophagy for intracellular replication. Cell Host and Microbe, 14 (6), 675-682. doi: 10.1016/j.chom.2013.11.003

Acquisition of the Sda1-encoding bacteriophage does not enhance virulence of the serotype M1 Streptococcus pyogenes strain SF370

Venturini, Carola, Ong, Cheryl-Iynn Y., Gillen, Christine M., Ben-Zakour, Nouri L., Maamary, Peter G., Nizet, Victor, Beatson, Scott A. and Walker, Mark J. (2013). Acquisition of the Sda1-encoding bacteriophage does not enhance virulence of the serotype M1 Streptococcus pyogenes strain SF370. Infection and Immunity, 81 (6), 2062-2069. doi: 10.1128/IAI.00192-13

Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus

Tsatsaronis, James A., Hollands, Andrew, Cole, Jason N., Maamary, Peter G., Gillen, Christine M., Ben Zakour, Nouri L., Kotb, Malak, Nizet, Victor, Beatson, Scott A., Mark J. Walker and Sanderson-Smith, Martina L. (2013). Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus. FASEB Journal, 27 (7), 2633-2643. doi: 10.1096/fj.12-226662

Streptokinase variants from Streptococcus pyogenes isolates display altered plasminogen activation characteristics - implications for pathogenesis

Cook, Simon M., Skora, Amanda, Gillen, Christine M., Walker, Mark J. and McArthur, Jason D. (2012). Streptokinase variants from Streptococcus pyogenes isolates display altered plasminogen activation characteristics - implications for pathogenesis. Molecular Microbiology, 86 (5), 1052-1062. doi: 10.1111/mmi.12037

Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone

Maamary, Peter G., Ben Zakour, Nouri L., Cole, Jason N., Hollands, Andrew, Aziz, Ramy K., Barnett, Timothy C., Cork, Amanda J., Henningham, Anna, Sanderson-Smith, Martina, McArthur, Jason D., Venturini, Carola, Gillen, Christine M., Kirk, Joshua K., Johnson, Dwight R., Taylor, William L., Kaplan, Edward L., Kotb, Malak, Nizet, Victor, Beatson, Scott A. and Walker, Mark J. (2012). Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone. FASEB Journal, 26 (11), 4675-4684. doi: 10.1096/fj.12-212142

Molecular characterization of the 2011 Hong Kong scarlet fever outbreak

Tse, Herman, Bao, Jessie Y. J., Davies, Mark R., Maamary, Peter, Tsoi, Hoi-Wah, Tong, Amy H. Y., Ho, Tom C. C., Lin, Chi-Ho, Gillen, Christine M., Barnett, Timothy C., Chen, Jonathan H. K., Lee, Mianne, Yam, Wing-Cheong, Wong, Chi-Kin, Ong, Cheryl-lynn Y., Chan, Yee-Wai, Wu, Cheng-Wei, Ng, Tony, Lim, Wilina W. L., Tsang, Thomas H. F., Tse, Cindy W. S., Dougan, Gordon, Walker, Mark J., Lok, Si and Yuen, Kwok-Yung (2012). Molecular characterization of the 2011 Hong Kong scarlet fever outbreak. The Journal of Infectious Diseases, 206 (3), 341-351. doi: 10.1093/infdis/jis362

Conserved anchorless surface proteins as group A streptococcal vaccine candidates

Henningham, Anna, Chiarot, Emiliano, Gillen, Christine M., Cole, Jason N., Rohde, Manfred, Fulde, Marcus, Ramachandran, Vidiya, Cork, Amanda J., Hartas, Jon, Magor, Graham, Djordjevic, Steven P., Cordwell, Stuart J., Kobe, Bostjan, Sriprakash, Kabada S., Nizet, Victor, Chhatwal, G. S., Margarit, Immaculada Y. R., Batzloff, Michael R. and Walker, Mark J. (2012). Conserved anchorless surface proteins as group A streptococcal vaccine candidates. Journal of Molecular Medicine, 90 (10), 1197-1207. doi: 10.1007/s00109-012-0897-9

Region specific and worldwide distribution of collagen-binding M proteins with PARF motifs among human pathogenic streptococcal isolates

Reibmann, Silvana, Gillen, Christine M., Fulde, Marcus, Bergmann, Rene, Nerlich, Andreas, Rajkumari, Reena, Brahmadathan, Kootallur N., Chhatwal, Gursharan S. and Nitsche-Schmitz, D. Patric (2012). Region specific and worldwide distribution of collagen-binding M proteins with PARF motifs among human pathogenic streptococcal isolates. PLoS One, 7 (1), e30122.1-e30122.11. doi: 10.1371/journal.pone.0030122

Contribution of plasminogen activation towards the pathogenic potential of oral streptococci

Itzek, Andreas, Gillen, Christine M., Fulde, Marcus, Friedrichs, Claudia, Rodloff, Arne C., Chhatwal, Gursharan S. and Nitsche-Schmitz, Daniel Patric (2010). Contribution of plasminogen activation towards the pathogenic potential of oral streptococci. PLoS One, 5 (11), e13826. doi: 10.1371/journal.pone.0013826

Identification of active variants of PARF in human pathogenic group C and group G streptococci leads to an amended description of its consensus motif

Barroso, Vanessa, Rohde, Manfred, Davies, Mark R., Gillen, Christine M., Nitsche-Schmitz, D. Patric, Dinkla, Katrin and Chhatwal, Gursharan S. (2009). Identification of active variants of PARF in human pathogenic group C and group G streptococci leads to an amended description of its consensus motif. International Journal of Medical Microbiology, 299 (8), 547-553. doi: 10.1016/j.ijmm.2009.04.004

Human pathogenic streptococcal proteomics and vaccine development

Cole, Jason N., Henningham, Anna, Gillen, Christine M., Ramachandran, Vidiya and Walker, Mark J. (2008). Human pathogenic streptococcal proteomics and vaccine development. Proteomics Clinical Applications, 2 (3), 387-410. doi: 10.1002/prca.200780048

Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete

Gillen, Christine M., Courtney, Harry S., Schulze, Kai, Rohde, Manfred, Wilson, Mark R., Timmer, Anjulli M., Guzman, Carlos A., Nizet, Victor, Chhatwal, G. s. and Walker, Mark J. (2008). Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete. Journal of Biological Chemistry, 283 (10), 6359-6366. doi: 10.1074/jbc.M706739200

Serum opacity factor promotes group A streptococcal epithelial cell invasion and virulence

Timmer, Anjuli M., Kristian, Sascha A., Datta, Vivekanand, Jeng, Arthur, Gillen, Christine M., Walker, Mark J., Beall, Bernard and Nizet, Victor (2006). Serum opacity factor promotes group A streptococcal epithelial cell invasion and virulence. Molecular Microbiology, 62 (1), 15-25. doi: 10.1111/j.1365-2958.2006.05337.x

Immunological response mounted by Aboriginal Australians living in the Northern Territory of Australia against Streptococcus pyogenes serum opacity factor

Gillen, Christine M., Towers, Rebecca J., McMillan, David J., Delvecchio, Armando, Sriprakash, Kadaba S., Currie, Bart, Kreikemeyer, Berndt, Chhatwal, Gurusharan S. and Walker, Mark J. (2002). Immunological response mounted by Aboriginal Australians living in the Northern Territory of Australia against Streptococcus pyogenes serum opacity factor. Microbiology, 148 (1), 169-178. doi: 10.1099/00221287-148-1-169

In vitro susceptibility testing of imipenem- relebactam and tedizolid against australian mycobacterium abscessus isolates

Burke, A. J., Carter, R., Tolson, C., Congdon, J., Duplancic, C., Bursle, E., Bell, S., Roberts, J. and Thomson, R. (2023). In vitro susceptibility testing of imipenem- relebactam and tedizolid against australian mycobacterium abscessus isolates. ATS 2023 International Conference, Washington, DC USA, 19-24 May 2023. Washington, DC USA: American Thoracic Society. doi: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2968

Non-tuberculous mycobacteria in Australians with cystic fibrosis: a national survey

Duplancic, C., Wainwright, C., Thomson, R., Rogers, G., Clements, A., Floto, R. and Bell, S. (2022). Non-tuberculous mycobacteria in Australians with cystic fibrosis: a national survey. TSANZSRS 2022 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ), Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, virtual, 31 March-2 April 2022. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/resp.14216

High incidence of non-tuberculous mycobacteria-positive cultures among children with cystic fibrosis in Australia

Duplancic, C., Thomson, R., Wainwright, C. and Bell, S. C. (2019). High incidence of non-tuberculous mycobacteria-positive cultures among children with cystic fibrosis in Australia. Unknown, Unknown, Unknown. Hoboken, NJ USA: John Wiley & Sons.

Non-tuberculous mycobacteria infection in people with cystic fibrosis attending cf treatment clinics in Australia

Duplancic, C., Wainwright, C., Thomson, R. and Bell, S. (2019). Non-tuberculous mycobacteria infection in people with cystic fibrosis attending cf treatment clinics in Australia. TSANZ, Gold Coast, QLD, Australia, 29 March-2 April 2019. Hoboken, NJ, United States: John Wiley & Sons.