The University of Queensland

Visualisation of [11C]CO2 storage in coal with positron emission tomography imaging

Jing, Yu, Uthaia Kumaran, Aaron, Stimson, Damion, Mardon, Karine, Najdovski, Ljubco, Barkhausen, Christoph, Armstrong, Ryan T. and Mostaghimi, Peyman (2024). Visualisation of [11C]CO2 storage in coal with positron emission tomography imaging. Fuel, 356 129511, 1-8. doi: 10.1016/j.fuel.2023.129511

Synthesis and preclinical evaluation of fluorinated 5-azaindoles as CB2 PET radioligands

Kallinen, Annukka, Mardon, Karine, Lane, Samuel, Montgomery, Andrew P., Bhalla, Rajiv, Stimson, Damion H. R., Ahamed, Muneer, Cowin, Gary J., Hibbs, David, Werry, Eryn L., Fulton, Roger, Connor, Mark and Kassiou, Michael (2023). Synthesis and preclinical evaluation of fluorinated 5-azaindoles as CB2 PET radioligands. ACS Chemical Neuroscience, 14 (16), 2902-2921. doi: 10.1021/acschemneuro.3c00345

Utilizing PET and MALDI imaging for discovery of a targeted probe for brain endocannabinoid α/β-hydrolase domain 6 (ABHD6)

Mardon, Karine, Patel, Jayendra Z., Savinainen, Juha R., Stimson, Damion H. R., Oyagawa, Caitlin R. M., Grimsey, Natasha L., Migotto, Mary-anne, Njiru, Grace F. M., Hamilton, Brett R., Cowin, Gary, Yli-Kauhaluoma, Jari, Vanduffel, Wim, Blakey, Idriss, Bhalla, Rajiv, Cawthorne, Christopher, Celen, Sofie, Bormans, Guy, Thurecht, Kristofer J and Ahamed, Muneer (2022). Utilizing PET and MALDI imaging for discovery of a targeted probe for brain endocannabinoid α/β-hydrolase domain 6 (ABHD6). Journal of Medicinal Chemistry, 66 (1), 538-552. doi: 10.1021/acs.jmedchem.2c01485

Simultaneous dual echo gadolinium enhanced MR-PET for evaluation of PET tracer delivery in altered pathophysiology

Cowin, Gary J, Mardon, Karine, Houston, Zachary H., Bhalla, Rajiv, Stimson, Damion H. R., Thurecht, Kristofer J. and Brereton, Ian M. (2022). Simultaneous dual echo gadolinium enhanced MR-PET for evaluation of PET tracer delivery in altered pathophysiology. Frontiers in Physics, 10 759749. doi: 10.3389/fphy.2022.759749

A binge high sucrose diet provokes systemic and cerebral inflammation in rats without inducing obesity

Patkar, Omkar L., Mohamed, Abdalla Z., Narayanan, Ashwin, Mardon, Karine, Cowin, Gary, Bhalla, Rajiv, Stimson, Damion H. R., Kassiou, Michael, Beecher, Kate, Belmer, Arnauld, Alvarez Cooper, Ignatius, Morgan, Michael, Hume, David A., Irvine, Katharine M., Bartlett, Selena E., Nasrallah, Fatima and Cumming, Paul (2021). A binge high sucrose diet provokes systemic and cerebral inflammation in rats without inducing obesity. Scientific Reports, 11 (1) 11252, 11252. doi: 10.1038/s41598-021-90817-z

GABAa receptor density alterations revealed in a mouse model of early moderate prenatal ethanol exposure using [18F]AH114726

Nguyen, Van T., Bhalla, Rajiv, Cowin, Gary, Stimson, Damion H.R., Song, Xin, Chong, Suyinn, Jackson, Alexander, Trigg, William J., Tieng, Quang M., Mardon, Karine, Galloway, Graham J. and Kurniawan, Nyoman D. (2020). GABAa receptor density alterations revealed in a mouse model of early moderate prenatal ethanol exposure using [18F]AH114726. Nuclear Medicine and Biology, 88-89, 44-51. doi: 10.1016/j.nucmedbio.2020.07.005

Synthesis and evaluation of 6-[18F]fluoro-3-(pyridin-3-yl)-1H-indole as potential PET tracer for targeting tryptophan 2, 3-dioxygenase (TDO)

Qiao, Zheng, Mardon, Karine, Stimson, Damion H.R., Migotto, Mary-anne, Reutens, David C. and Bhalla, Rajiv (2020). Synthesis and evaluation of 6-[18F]fluoro-3-(pyridin-3-yl)-1H-indole as potential PET tracer for targeting tryptophan 2, 3-dioxygenase (TDO). Nuclear Medicine and Biology, 84-85, 1-10. doi: 10.1016/j.nucmedbio.2019.12.007

Radiolabeling of protected tryptophan with [18F]fluoromethyl tosylate: Formation of [18F]fluoromethyl ester of tryptophan instead of 1-N-[18F]fluoromethyl tryptophan methylester

Venkatachalam, T.K., Stimson, D.H.R., Frisch, K., Pierens, G.K., Bhalla, R. and Reutens, D.C. (2019). Radiolabeling of protected tryptophan with [18F]fluoromethyl tosylate: Formation of [18F]fluoromethyl ester of tryptophan instead of 1-N-[18F]fluoromethyl tryptophan methylester. Applied Radiation and Isotopes, 152, 172-179. doi: 10.1016/j.apradiso.2019.06.039

Investigation on the impact of three different quaternary methyl ammonium cartridges on the radiosynthetic yields of [18F]fluoromethyl tosylate

Stimson, Damion H.R., Qiao, Zheng, Reutens, David, Venkatachalam, Taracad K. and Bhalla, Rajiv (2019). Investigation on the impact of three different quaternary methyl ammonium cartridges on the radiosynthetic yields of [18F]fluoromethyl tosylate. Journal of Labelled Compounds and Radiopharmaceuticals, 62 (9), 588-595. doi: 10.1002/jlcr.3781

Synthesis and: In vitro evaluation of fluorine-18 benzimidazole sulfones as CB2 PET-radioligands

Kallinen, Annukka, Boyd, Rochelle, Lane, Samuel, Bhalla, Rajiv, Mardon, Karine, Stimson, Damion H. R., Werry, Eryn L., Fulton, Roger, Connor, Mark and Kassiou, Michael (2019). Synthesis and: In vitro evaluation of fluorine-18 benzimidazole sulfones as CB2 PET-radioligands. Organic and Biomolecular Chemistry, 17 (20), 5086-5098. doi: 10.1039/c9ob00656g

Synthesis of 18F-radiolabeled diphenyl gallium dithiosemicarbazone using a novel halogen exchange method and in vivo biodistribution

Venkatachalam, T.K., Stimson, D.H.R., Bhalla, R., Mardon, K., Bernhardt, Paul.V. and Reutens, D.C. (2019). Synthesis of 18F-radiolabeled diphenyl gallium dithiosemicarbazone using a novel halogen exchange method and in vivo biodistribution. Journal of Labelled Compounds and Radiopharmaceuticals, 62 (7), 321-331. doi: 10.1002/jlcr.3746

Synthesis and characterisation of indium(iii) bis-thiosemicarbazone complexes: 18 F incorporation for PET imaging

Venkatachalam, Taracad K., Bernhardt, Paul V., Pierens, Gregory K., Stimson, Damion H. R., Bhalla, Rajiv and Reutens, David C. (2019). Synthesis and characterisation of indium(iii) bis-thiosemicarbazone complexes: 18 F incorporation for PET imaging. Australian Journal of Chemistry, 72 (5), 383-391. doi: 10.1071/CH18559

N-(4-[18F]fluorobenzyl)cholylglycine, a novel tracer for PET of enterohepatic circulation of bile acids: radiosynthesis and proof-of-concept studies in rats

Frisch, Kim, Stimson, Damion H. R., Venkatachalam, Taracad, Pierens, Gregory K., Keiding, Susanne, Reutens, David and Bhalla, Rajiv (2018). N-(4-[18F]fluorobenzyl)cholylglycine, a novel tracer for PET of enterohepatic circulation of bile acids: radiosynthesis and proof-of-concept studies in rats. Nuclear Medicine and Biology, 61, 56-62. doi: 10.1016/j.nucmedbio.2018.04.004

Challenges in the automated synthesis of [(18)F]-1-fluoroethyl tryptophan: Formation of both O- and N-alkylated products

Venkatachalam, T K, Stimson, D H R, Pierens, G K, Bhalla, R and Reutens, D C (2017). Challenges in the automated synthesis of [(18)F]-1-fluoroethyl tryptophan: Formation of both O- and N-alkylated products. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 131, 41-48. doi: 10.1016/j.apradiso.2017.10.047

A Novel Strategy to Introduce 18F, a Positron Emitting Radionuclide, into a Gallium Nitrate Complex: Synthesis, NMR, X-Ray Crystal Structure, and Preliminary Studies on Radiolabelling with 18F

Venkatachalam, Taracad K., Bernhardt, Paul V., Stimson, Damion H. R., Pierens, Gregory K., Bhalla, Rajiv and Reutens, David C. (2017). A Novel Strategy to Introduce 18F, a Positron Emitting Radionuclide, into a Gallium Nitrate Complex: Synthesis, NMR, X-Ray Crystal Structure, and Preliminary Studies on Radiolabelling with 18F. Australian Journal of Chemistry, 71 (3), 81-86. doi: 10.1071/CH17334

Heteronuclear NMR spectroscopic investigations of gallium complexes of substituted thiosemicarbazones including x-ray crystal structure, a new halogen exchange strategy, and 18F radiolabelling

Venkatachalam, T. K., Pierens, G. K., Bernhardt, Paul. V., Stimson, D. H. R., Bhalla, R., Lambert, L. and Reutens, D. C. (2016). Heteronuclear NMR spectroscopic investigations of gallium complexes of substituted thiosemicarbazones including x-ray crystal structure, a new halogen exchange strategy, and 18F radiolabelling. Australian Journal of Chemistry, 69 (9), 1033-1048. doi: 10.1071/CH16044

Management of radioactive waste gases from PET radiopharmaceutical synthesis using cost effective capture systems integrated with a cyclotron safety system

Stimson, D. H. R., Pringle, A. J., Maillet, D., King, A. R., Nevin, S. T., Venkatachalam, T. K., Reutens, D. C. and Bhalla, R. (2016). Management of radioactive waste gases from PET radiopharmaceutical synthesis using cost effective capture systems integrated with a cyclotron safety system. Journal of Radiological Protection, 36 (3), 504-517. doi: 10.1088/0952-4746/36/3/504

Synthesis, characterization and 11C radiolabeling of aminophenyl benzothiazoles:structural effects on the alkylation of amino group

Venkatachalam, T. K., Stimson, D. H. R., Bhalla, R., Pierens, G. K. and Reutens, D. C. (2014). Synthesis, characterization and 11C radiolabeling of aminophenyl benzothiazoles:structural effects on the alkylation of amino group. Journal of Labelled Compounds and Radiopharmaceuticals, 57 (9), 566-573. doi: 10.1002/jlcr.3216

Development of novel [F-18]thiosemicarbazone metal fluoride complexes as potential neuroimaging agents

Stimson, D., Venkatachalam, T. K., Pierens, G. K., Bernhardt, P. V., Mardon, K., Reutens, D. C. and Bhalla, R. (2019). Development of novel [F-18]thiosemicarbazone metal fluoride complexes as potential neuroimaging agents. 32nd Annual Congress of the European Association of Nuclear Medicine (EANM), Barcelona, Spain, 12-16 October 2019. Heidelberg, Germany: Springer.

Fluorinated benzimidazole sulfones as candidate radioligands for CB2 PET-imaging

Kallinen, Annukka, Boyd, Rochelle, Lane, Samuel, Bhalla, Rajiv, Mardon, Karine, Stimson, Damion, Cowin, Gary, Nasrallah, Fatima, Werry, Eryn, Connor, Mark and Kassiou, Michael (2019). Fluorinated benzimidazole sulfones as candidate radioligands for CB2 PET-imaging. 23rd International Symposium on Radiopharmaceutical Sciences (ISRS 2019), Beijing, China, 26-31 May 2019. Oxford, United Kingdom: John Wiley & Sons.

Proof-of-Concept for Positron Emission Tomography of the Enterohepatic Circulation of Conjugated Bile Acids in Rats

Frisch, Kim, Stimson, Damion H., Venkatachalam, Taracad, Pierens, Greg, Keiding, Susanne, Reutens, David and Bhalla, Rajiv (2017). Proof-of-Concept for Positron Emission Tomography of the Enterohepatic Circulation of Conjugated Bile Acids in Rats. 68th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) / Liver Meeting, Washington DC, 20-24 October 2017 . Hoboken, NJ, United States: John Wiley & Sons.

A FULLY INTEGRATED, COST-EFFECTIVE AND SOPHISTICATED CAPTURE SYSTEM FOR RADIOACTIVE GASES GENERATED DURING AUTOMATED RADIOPHARMACEUTICAL SYNTHESIS

Stimson, D., Pringle, A., Maillet, D., Bhalla, R., Venkatachalam, T. and Reutens, D. (2015). A FULLY INTEGRATED, COST-EFFECTIVE AND SOPHISTICATED CAPTURE SYSTEM FOR RADIOACTIVE GASES GENERATED DURING AUTOMATED RADIOPHARMACEUTICAL SYNTHESIS. HOBOKEN: WILEY-BLACKWELL.

A fully integrated, cost-effective and sophisticated capture system for radioactive gases generated during automated radiopharmaceutical synthesis

Stimson, D., Pringle, A., Maillet, D., Bhalla, R., Venkatachalam, T. and Reutens, D. (2015). A fully integrated, cost-effective and sophisticated capture system for radioactive gases generated during automated radiopharmaceutical synthesis. 45th Annual meeting of the Australian & New Zealand Society of Nuclear Medicine, Brisbane, 17–20 April 2015. doi: 10.1111/imj.12729

Cost effective and integrated capture systems for radioactive gases generated during automated C-11 and F-18 radiopharmaceutical synthesis

Stimson, D. H. R., Pringle, A. J., Maillet, D., King, A. R., Nevin, S.T., Venkatachalam, T.K., Reutens, D.C. and Bhalla, R (2015). Cost effective and integrated capture systems for radioactive gases generated during automated C-11 and F-18 radiopharmaceutical synthesis. 28th Annual Congress of the European Association of Nuclear Medicine (EANM), Hamburg, Germany, Oct 10-14, 2015. Heidelberg, Germany: Springer. doi: 10.1007/s00259-015-3198-z

The establishment of a PET radiopharmaceutical research and production facility at the centre for advanced imaging

Stimson, Damion, Fulcher, Tim, Reed, Larry and Reutens, David (2013). The establishment of a PET radiopharmaceutical research and production facility at the centre for advanced imaging. 43rd Annual Scientific Meeting of the Australian and New Zealand Society of Nuclear Medicine (ANZSNM), Perth, Australia, 11-15 April. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.

Preparation and Quality Control of 4-[F-18] Fluorobenzaldehyde: a Versatile Intermediate for Pet Tracer Syntheses

Stimson, D., Bourdier, T., Katsifis, A., Henderson, D., Lam, P., Poon, J. and Fulham, M. (2012). Preparation and Quality Control of 4-[F-18] Fluorobenzaldehyde: a Versatile Intermediate for Pet Tracer Syntheses. HOBOKEN: WILEY-BLACKWELL.

(68)Ga-dotatate: synthesis, automation, and quality control

Stimson, D., Macfarlane, D., Combs, M. and Yordanov, A. (2011). (68)Ga-dotatate: synthesis, automation, and quality control. 41st Annual Scientific Meeting of the Australian and New Zealand Society of Nuclear Medicine, Darwin, NT, Australia, 14 ‐ 18 July 2011. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia.

Radiopeptide lite - an automated radiopeptide labelling system using disposable cassettes

Combs, M., Stimson, D., Yordanov, A. and Macfarlane, D. (2011). Radiopeptide lite - an automated radiopeptide labelling system using disposable cassettes. 41st Annual Scientific Meeting of the Australian and New Zealand Society of Nuclear Medicine, Darwin, NT, Australia, 14 ‐ 18 July 2011. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia.

[Ga-68]DOTAtate: Fully Automated Synthesis and Quality Control

Stimson, Damion, MacFarlane, David, Combs, Mathew and Yordanov, Alex (2011). [Ga-68]DOTAtate: Fully Automated Synthesis and Quality Control. MALDEN: WILEY-BLACKWELL.

Non-HPLC Methods for the Production of F-18, C-11 and Ga-68 Radiopharmaceuticals

Yordanov, A., Combs, M. J., Shulman, S., Stimson, D., Mueller, M., Soylu, A., Bagci, H. and LeBars, D. (2010). Non-HPLC Methods for the Production of F-18, C-11 and Ga-68 Radiopharmaceuticals. 23rd Annual Congress of the European-Association-of-Nuclear-Medicine (EANM), Vienna Austria, Oct 09-13, 2010. NEW YORK: SPRINGER.

Preparation of 6-[F-18]Fluoro-L-Dopa Using Carrier Added [F-18]F-2 Produced by a Commercially Available Proton Target

Stimson, D. and Smith, J. G. (2009). Preparation of 6-[F-18]Fluoro-L-Dopa Using Carrier Added [F-18]F-2 Produced by a Commercially Available Proton Target. MALDEN: WILEY-BLACKWELL.