The University of Queensland

Using a next-generation sequencing approach to profile MicroRNAs from human origin

Guanzon, Dominic, Iljas, Juvita Delancy, Rice, Gregory E. and Salomon, Carlos (2017). Using a next-generation sequencing approach to profile MicroRNAs from human origin. In Preeclampsia methods and protocols (pp. 203-217) New York, NY United States: Humana Press. doi:10.1007/978-1-4939-7498-6_16

Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus

Nair, Soumyalekshmi, Guanzon, Dominic, Jayabalan, Nanthini, Lai, Andrew, Scholz-Romero, Katherin, Kalita de Croft, Priyakshi, Ormazabal, Valeska, Palma, Carlos, Diaz, Emilio, McCarthy, Elizabeth A., Shub, Alexis, Miranda, Jezid, Gratacós, Eduard, Crispi, Fátima, Duncombe, Gregory, Lappas, Martha, McIntyre, H. David, Rice, Gregory and Salomon, Carlos (2021). Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus. Journal of Translational Medicine, 19 (1) 360, 1-17. doi: 10.1186/s12967-021-02999-9

Partial Epithelial‐Mesenchymal Transition: Reduced miR‐4792 and miR‐146b‐5p Inversely Correlated with SIAH2 in Migrating Keratinocytes <i>in Vitro</i>

Wager, Lucas J., Guanzon, Dominic, Leavesley, David I., Thompson, Erik W. and Murray, Rachael Z. (2021). Partial Epithelial‐Mesenchymal Transition: Reduced miR‐4792 and miR‐146b‐5p Inversely Correlated with SIAH2 in Migrating Keratinocytes in Vitro. Experimental Dermatology, 30 (12), 1838-1839. doi: 10.1111/exd.14426

Extracellular vesicle transmission of chemoresistance to ovarian cancer cells is associated with hypoxia-induced expression of glycolytic pathway proteins, and prediction of epithelial ovarian cancer disease recurrence

Alharbi, Mona, Lai, Andrew, Sharma, Shayna, Kalita-De Croft, Priyakshi, Godbole, Nihar, Campos, America, Guanzon, Dominic, Salas-Burgos, Alexis, Carrion, Flavio, Zuñiga, Felipe A., Perrin, Lewis, He, Yaowu, Pejovic, Tanja, Winters, Carmen, Morgan, Terry, Hooper, John D., Rice, Gregory E. and Salomon, Carlos (2021). Extracellular vesicle transmission of chemoresistance to ovarian cancer cells is associated with hypoxia-induced expression of glycolytic pathway proteins, and prediction of epithelial ovarian cancer disease recurrence. Cancers, 13 (14) 3388, 1-26. doi: 10.3390/cancers13143388

miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer

Alharbi, Mona, Sharma, Shayna, Guanzon, Dominic, Lai, Andrew, Zuñiga, Felipe, Shiddiky, Muhammad J.A., Yamauchi, Yusuke, Salas-Burgos, Alexis, He, Yaowu, Pejovic, Tanja, Winters, Carmen, Morgan, Terry, Perrin, Lewis, Hooper, John D. and Salomon, Carlos (2020). miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer. Nanomedicine: Nanotechnology, Biology, and Medicine, 28 102207, 102207. doi: 10.1016/j.nano.2020.102207

Protein profile changes in circulating placental extracellular vesicles in term and preterm births: a longitudinal study

Menon, Ramkumar, Debnath, Chirantan, Lai, Andrew, Guanzon, Dominic, Bhatnagar, Shinjini, Kshetrapal, Pallavi, Sheller-Miller, Samantha, Salomon, Carlos and The Garbh-Ini Study team (2020). Protein profile changes in circulating placental extracellular vesicles in term and preterm births: a longitudinal study. Endocrinology, 161 (4) bqaa009. doi: 10.1210/endocr/bqaa009

Regulation of glucose homeostasis by small extracellular vesicles in normal pregnancy and in gestational diabetes

James-Allan, Laura B., Rosario, Frederick J., Barner, Kelsey, Lai, Andrew, Guanzon, Dominic, McIntyre, H. David, Lappas, Martha, Powell, Theresa L., Salomon, Carlos and Jansson, Thomas (2020). Regulation of glucose homeostasis by small extracellular vesicles in normal pregnancy and in gestational diabetes. FASEB Journal, 34 (4) fj.201902522RR, 5724-5739. doi: 10.1096/fj.201902522RR

Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess

Tapia-Castillo, Alejandra, Guanzon, Dominic, Palma, Carlos, Lai, Andrew, Barros, Eric, Allende, Fidel, Vecchiola, Andrea, Fardella, Carlos E., Salomón, Carlos and Carvajal, Cristian A. (2019). Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess. Journal of Translational Medicine, 17 (1) 392, 392. doi: 10.1186/s12967-019-02143-8

Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells

Alharbi, Mona, Lai, Andrew, Guanzon, Dominic, Palma, Carlos, Zuñiga, Felipe, Perrin, Lewis, He, Yaowu, Hooper, John D and Salomon, Carlos (2019). Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells. Clinical Science, 133 (13), CS20190082-1419. doi: 10.1042/cs20190082

Quantitative proteomics by SWATH-MS of maternal plasma exosomes determine pathways associated with term and preterm birth

Menon, Ramkumar, Dixon, Christopher Luke, Sheller-Miller, Samantha, Fortunato, Stephen J., Saade, George R., Palma, Carlos, Lai, Andrew, Guanzon, Dominic and Salomon, Carlos (2019). Quantitative proteomics by SWATH-MS of maternal plasma exosomes determine pathways associated with term and preterm birth. Endocrinology, 160 (3), 639-650. doi: 10.1210/en.2018-00820

Quantitative proteomics by SWATH-MS suggest an association between circulating exosomes and maternal metabolic changes in gestational diabetes mellitus

Jayabalan, Nanthini, Lai, Andrew, Nair, Soumyalekshmi, Guanzon, Dominic, Scholz-Romero, Katherin, Palma, Carlos, McIntyre, Harold David, Lappas, Martha and Salomon, Carlos (2019). Quantitative proteomics by SWATH-MS suggest an association between circulating exosomes and maternal metabolic changes in gestational diabetes mellitus. Proteomics, 19 (1-2) 1800164, e1800164. doi: 10.1002/pmic.201800164

Adipose tissue exosomal proteomic profile reveals a role on placenta glucose metabolism in gestational diabetes mellitus

Jayabalan, Nanthini, Lai, Andrew, Ormazabal, Valeska, Adam, Stefanie, Guanzon, Dominic, Palma, Carlos, Scholz-Romero, Katherin, Lim, Ratana, Jansson, Thomas, McIntyre, Harold David, Lappas, Martha and Salomon, Carlos (2018). Adipose tissue exosomal proteomic profile reveals a role on placenta glucose metabolism in gestational diabetes mellitus. The Journal of Clinical Endocrinology & Metabolism, 104 (5) jcem-201801599, 1735-1752. doi: 10.1210/jc.2018-01599

The potential role of miRNAs and exosomes in chemotherapy in ovarian cancer

Alharbi, Mona, Zuñiga, Felipe, Elfeky, Omar, Guanzon, Dominic, Lai, Andrew, Rice, Gregory E., Perrin, Lewis, Hooper, John and Salomon, Carlos (2018). The potential role of miRNAs and exosomes in chemotherapy in ovarian cancer. Endocrine-Related Cancer, 25 (12), R663-R685. doi: 10.1530/erc-18-0019

Human placental exosomes in gestational diabetes mellitus carry a specific set of miRNAs associated with skeletal muscle insulin sensitivity

Nair, Soumyalekshmi, Jayabalan, Nanthini, Guanzon, Dominic, Palma, Carlos, Scholz-Romero, Katherin, Elfeky, Omar, Zuñiga, Felipe, Ormazabal, Valeska, Diaz, Emilio, Rice, Gregory E., Duncombe, Gregory, Jansson, Thomas, McIntyre, Harold David, Lappas, Martha and Salomon, Carlos (2018). Human placental exosomes in gestational diabetes mellitus carry a specific set of miRNAs associated with skeletal muscle insulin sensitivity. Clinical Science, 132 (22), 2451-2467. doi: 10.1042/cs20180487

Circulating exosomal miRNA profile during term and preterm birth pregnancies - a longitudinal study

Menon, Ramkumar, Debnath, Chirantan, Lai, Andrew, Guanzon, Dominic, Bhatnagar, Shinjini, Pallavi, S. K., Sheller-Miller, Samantha, The Garbhini Study team and Salomon, Carlos (2018). Circulating exosomal miRNA profile during term and preterm birth pregnancies - a longitudinal study. Endocrinology, 160 (2), 249-275. doi: 10.1210/en.2018-00836

Circulating cell-free miR-494 and miR-21 are disease response biomarkers associated with interim-positron emission tomography response in patients with diffuse large b-cell lymphoma

Cui, Qingyan, Vari, Frank, Cristino, Alexandre S., Salomon, Carlos, Rice, Gregory E., Sabdia, Muhammed B., Guanzon, Dominic, Palma, Carlos, Mathew, Marina, Talaulikar, Dipti, Jain, Sanjiv, Han, Erica, Hertzberg, Mark S., Gould, Clare, Crooks, Pauline, Thillaiyampalam, Gayathri, Keane, Colm and Gandhi, Maher K. (2018). Circulating cell-free miR-494 and miR-21 are disease response biomarkers associated with interim-positron emission tomography response in patients with diffuse large b-cell lymphoma. Oncotarget, 9 (78), 34644-34657. doi: 10.18632/oncotarget.26141

Proteomic analysis of exosomes reveals an association between cell invasiveness and exosomal bioactivity on endothelial and mesenchymal cell migration

Sharma, Shayna, Alharbi, Mona, Kobayashi, Miharu, Lai, Andrew, Guanzon, Dominic, Zuñiga, Felipe, Ormazabal, Valeska, Palma, Carlos, Scholz-Romero, Katherin, Rice, Gregory E., Hooper, John D. and Salomon, Carlos (2018). Proteomic analysis of exosomes reveals an association between cell invasiveness and exosomal bioactivity on endothelial and mesenchymal cell migration. Clinical Science, 132 (18), 2029-2044. doi: 10.1042/CS20180425

Differential expression of keratinocyte-derived extracellular vesicle mirnas discriminate exosomes from apoptotic bodies and microvesicles

Than, Uyen T. T., Guanzon, Dominic, Broadbent, James A., Leavesley, David, Salomon, Carlos and Parker, Tony J. (2018). Differential expression of keratinocyte-derived extracellular vesicle mirnas discriminate exosomes from apoptotic bodies and microvesicles. Frontiers in Endocrinology, 9 (SEP) 535, 1-15. doi: 10.3389/fendo.2018.00535

Amniotic fluid exosome proteomic profile exhibits unique pathways of term and preterm labor

Dixon, C. Luke, Sheller-Miller, Samantha, Saade, George R., Fortunato, Stephen J., Lai, Andrew, Palma, Carlos, Guazon, Dominic, Salomon, Carlos and Menon, Ramkumar (2018). Amniotic fluid exosome proteomic profile exhibits unique pathways of term and preterm labor. Endocrinology, 159 (5), 2229-2240. doi: 10.1210/en.2018-00073

Placental Exosomes as Early Biomarker of Preeclampsia: Potential Role of Exosomal MicroRNAs Across Gestation

Salomon, Carlos, Guanzon, Dominic, Scholz-Romero, Katherin, Longo, Sherri, Correa, Paula, Illanes, Sebastian E. and Rice, Gregory E. (2017). Placental Exosomes as Early Biomarker of Preeclampsia: Potential Role of Exosomal MicroRNAs Across Gestation. Journal of Clinical Endocrinology & Metabolism, 102 (9), 3182-3194. doi: 10.1210/jc.2017-00672

Bio-compartmentalization of microRNAs in exosomes during gestational diabetes mellitus

Iljas, Juvita D., Guanzon, Dominic, Elfeky, Omar, Rice, Gregory E. and Salomon, Carlos (2017). Bio-compartmentalization of microRNAs in exosomes during gestational diabetes mellitus. Placenta, 54, 76-82. doi: 10.1016/j.placenta.2016.12.002

Oxygen tension regulates the miRNA profile and bioactivity of exosomes released from extravillous trophoblast cells-liquid biopsies for monitoring complications of pregnancy

Truong, Grace, Guanzon, Dominic, Kinhal, Vyjayanthi, Elfeky, Omar, Lai, Andrew, Longo, Sherri, Nuzhat, Zarin, Palma, Carlos, Scholz-Romero, Katherin, Menon, Ramkumar, Mol, Ben W., Rice, Gregory E. and Salomon, Carlos (2017). Oxygen tension regulates the miRNA profile and bioactivity of exosomes released from extravillous trophoblast cells-liquid biopsies for monitoring complications of pregnancy. PLoS ONE, 12 (3) e0174514, e0174514. doi: 10.1371/journal.pone.0174514

Exosome profiles for normal and complicated pregnancies - a longitudinal study

Nakahara, Angela, Elfeky, Omar, Garvey, Cathryn, Guanzon, Dominic, Longo, Sherri Anne and Salmon, Carlos (2019). Exosome profiles for normal and complicated pregnancies - a longitudinal study. Annual Clinical and Scientific Meeting of the American College of Obstetricians and Gynecologists, Nashville, TN United States, 3-6 May 2019. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/01.AOG.0000558864.31601.AA

Exosome profiles for normal and complicated pregnancies - a longitudinal study

Nakahara, A., Elfeky, O., Garvey, C., Guanzon, D., Longo, S. and Salomon, C. (2019). Exosome profiles for normal and complicated pregnancies - a longitudinal study. AFMR/SAFMR/SSCI/SSPR Southern Regional Meetings, New Orleans, LA, United States, 21-23 February 2019. London, United Kingdom: BMJ Group. doi: 10.1136/jim-2018-000974.651

Circulating exosomal miRNAs from women with ovarian cancer for early detection and real-time monitoring of disease progression

Sharma, Shayna, Lai, Andrew, Guanzon, Dominic, Morgan, Terry, Perrin, Lewis C., Hooper, John D. and Salomon, Carlos (2019). Circulating exosomal miRNAs from women with ovarian cancer for early detection and real-time monitoring of disease progression. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage Publications. doi: 10.1177/1933719119834079

Exosomal MiRNA profile in exosomes isolated from adipose tissue explants from normal and gestational diabetes mellitus pregnancies

Jayabalan, Nanthini, Guanzon, Dominic, McIntyre, David, Lappas, Martha and Salomon, Carlos (2019). Exosomal MiRNA profile in exosomes isolated from adipose tissue explants from normal and gestational diabetes mellitus pregnancies. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI) , Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage.

Exosomal protein and miRNA analysis in cervico-vaginal fluid at early gestation from term and preterm pregnancies

Tribe, Rachel M., Jenkins, Holly, Palma, Carlos, Lai, Andrew, Guanzon, Dominic, Hezelgrave, Natasha L., Shennan, Andrew H. and Salomon, Carlos (2019). Exosomal protein and miRNA analysis in cervico-vaginal fluid at early gestation from term and preterm pregnancies. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12 - 16 March 2019. Thousand Oaks, CA, United States: Sage Publications. doi: 10.1177/1933719119834079

Integrative Analysis of Multi-Omics Exosomal Data for Identifying Multi-Markers for Susceptibility to Chemotherapy in Ovarian Cancer

Alharbi, Mona, Lai, Andrew, Guanzon, Dominic, Sharma, Shayna, Palma, Carlos, Zuniga, Felipe, Rice, Gregory E., Perrin, Lewis, Hooper, John D. and Salomon, Carlos (2018). Integrative Analysis of Multi-Omics Exosomal Data for Identifying Multi-Markers for Susceptibility to Chemotherapy in Ovarian Cancer. 65th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), San Diego Ca United States, 6-10 March 2018. Thousand Oaks, CA United States: Sage.

Interactions between placental exosomes and skeletal muscle implication in cell metabolism in gestational diabetes mellitus

Nair, Soumyalekshmi, Jayabalan, Nanthini, Guanzon, Dominic, Lai, Andrew, Scholz-Romero, Katherin, Elfeky, Omar, Zuniga, Felipe, Diaz, Emilio, McIntyre, David, Rice, Gregory E., Lappas, Martha and Salomon, Carlos (2018). Interactions between placental exosomes and skeletal muscle implication in cell metabolism in gestational diabetes mellitus. 65th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), San Diego, CA, United States, 6-10 March 2018. Thousand Oaks, CA, United States: Sage. doi: 10.1177/1933719118759999

Exosomal content in the plasma of patients with ovarian cancer reflect tumor state and induce the epithelial to mesenchymal transition in target cells

Sharma, Shayna, Scholz-Romero, Katherin, Kline, Richard, Wade, Katrina, Estes, Jacob, Palma, Carlos, Guanzon, Dominic, Lai, Andrew, Hooper, John, Rice, Gregory E. and Salomon, Carlos (2017). Exosomal content in the plasma of patients with ovarian cancer reflect tumor state and induce the epithelial to mesenchymal transition in target cells. 64th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Orlando, FL, United States, 15-18 March 2017. Thousand Oaks, CA, United States: Sage Publications. doi: 10.1177/1933719117699773

Characterisation of adipose tissue-derived exosomes in normal and diabetes mellitus pregnancies: Potential role of exosomal miRNAs

Jayabalan, Nanthini, Guanzon, Dominic, Lai, Andrew, McIntyre, David, Jansson, Thomas, Rice, Gregory E., Lappas, Martha and Salomon, Carlos (2017). Characterisation of adipose tissue-derived exosomes in normal and diabetes mellitus pregnancies: Potential role of exosomal miRNAs. Meeting of the International-Federation-of-Placenta-Associations (IFPA), Manchester, United Kingdom, Aug 30-Sep 2 2017. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2017.07.133

Exosomes present in circulation of women with gestational diabetes mellitus carry a specific set of microRNAs associated with insulin resistant

Guanzon, Dominic, Jayabalan, Nanthini, Palma, Carlos, Nair, Soumyalekshmi, Scholz-Romero, Katherin, Kinhal, Vyjayanthi, Lai, Andrew, McIntyre, David, Jansson, Thomas, Rice, Gregory, Lappas, Martha and Salomon, Carlos (2017). Exosomes present in circulation of women with gestational diabetes mellitus carry a specific set of microRNAs associated with insulin resistant. Meeting of the International-Federation-of-Placenta-Associations (IFPA), Manchester, United Kingdom, Aug 30-Sep 2 2017. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2017.07.134

Next-Generation miRNA Sequencing Reveals That Exosomes Present in Maternal Circulation of Gestational Diabetes Pregnancies Regulate Glucose Metabolism in Placental Cells

Adam, Stefanie, Guanzon, Dominic, Scholz-Romero, Katherin, Elfeky, Omar, Longo, Sherri, Lai, Andrew, Duncombe, Gregory, Rice, Gregory E., Lappas, Martha and Salomon, Carlos (2017). Next-Generation miRNA Sequencing Reveals That Exosomes Present in Maternal Circulation of Gestational Diabetes Pregnancies Regulate Glucose Metabolism in Placental Cells. 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Orlando, FL, United States, 15-18 March 2017. Thousand Oaks, CA, United States: Sage Publications. doi: 10.1177/1933719117699773

Characterization of exosomal mirnas present in plasma from women with gestational diabetes mellitus

Salomon, Carlos, Guanzon, Dominic, Rice, Gregory and Lappas, Martha (2016). Characterization of exosomal mirnas present in plasma from women with gestational diabetes mellitus. Meeting of the International Federation of Placenta Associations (IFPA) - Placenta - Back to the Basics, Portland, United States, 13-16 September 2016. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2016.06.028

Identification of exosomal mirna biomarkers at early gestation (&lt; 18 Weeks) in asymptomatic women at early gestation (&lt; 18 Weeks) who subsequently develop spontaneous preterm birth

Kinhal, Vyjayanthi, Guanzon, Dominic, Scholz-Romero, Katherin, Longo, Sherri, Fortunato, Stephen, Menon, Ramkumar, Rice, Gregory and Salomon, Carlos (2016). Identification of exosomal mirna biomarkers at early gestation (< 18 Weeks) in asymptomatic women at early gestation (< 18 Weeks) who subsequently develop spontaneous preterm birth. Meeting of the International Federation of Placenta Associations (IFPA) - Placenta - Back to the Basics, Portland, United States, Sep 13-16, 2016. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2016.06.222