Dr Tatiane Yanes

Research Fellow

Frazer Institute
Faculty of Medicine

Overview

I am a clinician-researcher based at the Integrating Genomics into Medicine group and at the Queensland Children’s Hospital. My research is informed by my clinical experience as a genetic counsellor, where I support families undergoing genetic testing, provide genetic risk assessment, and assist families cope and adapt to their genetic diagnosis. My research has been recognised through multiple awards including Rising Star Award in 2021 by both the University of QLD Faculty of Medicine and Frazer Insitute.

My research focuses on the implementation of genomic technologies in healthcare, with expertise in polygenic risk (PGS). My current projects include:

  • developing educational modules on PGS for healthcare providers,
  • evaluating the impact of providing PGS on health behaviour and patient reported outcomes,
  • establishing pathways for laboratory accreditation of PGS in Australia,
  • developing a framework to increase participation of diverse communities in genomics research and,
  • mainstreaming genomic testing for peadiatric healthcare, with a focus on inborn errors of immunity

Research Interests

  • Developing a toolkit to support implementation of polygenic risk scores
    Our project aims to support the implementation of polygenic risk (PGS) by developing i) online education for genetic and non-genetic healthcare providers ii) materials for patient education and risk communication iii) evaluating the ethical, legal and social implications of PGS
  • Mainstreaming genomic testing in paediatric setting
    Our project aims to support the mainstreaming of genomic testing for children with intellectual impairment or an inborn error of immunity. We develop and evaluate training for non-genetics providers and apply a mixed-method approach to evaluate the experiences of parents who accessed genomic testing for their children.

Qualifications

  • Doctor of Philosophy, University of New South Wales
  • Masters (Coursework), Griffith University
  • Bachelor, Australian National University

Publications

  • Yanes, Tatiane, Tiller, Jane, Haining, Casey M., Wallingford, Courtney, Otlowski, Margaret, Keogh, Louise, McInerney-Leo, Aideen and Lacaze, Paul (2024). Future implications of polygenic risk scores for life insurance underwriting. npj Genomic Medicine, 9 (1) 25. doi: 10.1038/s41525-024-00407-x

  • Yanes, Tatiane, Blencoe, Marisa, Howard, Antonia, Tiller, Jane, Wallingford, Courtney, Otlowski, Margaret, Keogh, Louise, Lacaze, Paul and McInerney‐Leo, Aideen (2024). Australian researcher's perspectives on the Australian industry‐led moratorium on genetic tests in life insurance. American Journal of Medical Genetics Part A, 194 (6) e63565. doi: 10.1002/ajmg.a.63565

  • Wallingford, Courtney, Law, Matthew, Mothershaw, Adam, Acevedo, Astrid Rodriguez, Soyer, Hans Peter, McInerney-Leo, Aideen and Yanes, Tatiane (2024). Evaluating a protocol for communicating melanoma personalised risk scores: a pilot study. 56th Annual Conference of the European-Society-of-Human-Genetics (ESHG), Glasgow, Scotland, 10-13 June 2023. London, United Kingdom: Nature Publishing Group.

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Journal Article

Conference Publication

  • Wallingford, Courtney, Law, Matthew, Mothershaw, Adam, Acevedo, Astrid Rodriguez, Soyer, Hans Peter, McInerney-Leo, Aideen and Yanes, Tatiane (2024). Evaluating a protocol for communicating melanoma personalised risk scores: a pilot study. 56th Annual Conference of the European-Society-of-Human-Genetics (ESHG), Glasgow, Scotland, 10-13 June 2023. London, United Kingdom: Nature Publishing Group.

  • Yanes, Tatiane, Sullivan, Anna, Barbaro, Pasquale, Brion, Kristian, Peake, Jane and McNaughton, Peter (2023). Mainstreaming genomic testing for children with undiagnosed inborn errors of immunity. 55th European-Society-of-Human-Genetics (ESHG) Conference, Vienna Austria, Jun 11-14, 2022. LONDON: SPRINGERNATURE.

  • Wallingford, Courtney, Kovilpillai, Hannah, Jacobs, Chris, Turbitt, Erin, Primiero, Clare, Brockman, Deanna, Soyer, Hans Peter, McInerney-Leo, Aideen and Yanes, Tatiane (2023). Models of communication for polygenic scores and associated behavioural and psychological outcomes: a systematic review. 55th European Society of Human Genetics (ESHG) Conference, Vienna, Austria, 11-14 June 2022. London, United Kingdom: Nature Publishing Group.

  • Yanes, T., Kaur, R., Meiser, B., Scheepers-Joynt, M., McInerny, S., Barlow-Stewart, K., Antill, Y., Salmon, L., Smyth, C., Halliday, J., James, P. and Young, M. (2019). High-risk women's responses and understanding of polygenic breast cancer risk information. 52nd Conference of the European-Society-of-Human-Genetics (ESHG), Gothenburg, Sweden, 15-18 June 2019 . London, United Kingdom: Nature Publishing Group.

  • Yanes, T., Meiser, B., Kaur, R., Scheepers-Joynt, M., Young, M., Barlow-Stewart, K., John, T., Harris, M., Antill, Y., Halliday, J., Burke, J., Roscioli, T., Mitchell, P. and James, P. (2019). Uptake of polygenic risk information among women at potentially high breast cancer risk. 51st Conference of the European-Society-of-Human-Genetics (ESHG) in conjunction with the European Meeting on Psychosocial Aspects of Genetics (EMPAG), Milan, Italy, 16-19 June 2018. London, United Kingdom: Nature Publishing Group.

  • Yanes, Tatiane, Meiser, Bettina, Kaur, Rajneesh, Scheepers-Joynt, Maatje, Young, Mary-Anne, Barlow-Stewart, Kristine, John, Tom, Harris, Marrion, Antill, Yoland, Burke, Jo, Roscioli, Tony, Halliday, Jane, Mitchell, Phillip and James, Paul A (2018). Polygenic breast cancer risk: A prospective study of uptake and outcomes among high-risk women. 42nd Human Genetics Society of Australasia Annual Scientific Meeting, Sydney, NSW, Australia, 4-7th August 2018. Cambridge, United Kingdom: Cambridge University Press.

PhD and MPhil Supervision

Current Supervision