Dr Ibrahim Javed

Postdoctoral Research Fellow

Australian Institute for Bioengineering and Nanotechnology

Overview

Dr. Ibrahim Javed is Postdoctoral Research Fellow at ARC Centre of Excellence in Convergent Nano-Bio Science and Technology and Australian Institute for Bioengineering and Nanotechnology at The University of Queensland. He earned his PhD degree from Monash Institute of Pharmaceutical Sciences at Monash University in 2019. Prior to PhD, Dr. Javed had graduated with Doctor of Pharmacy degree (2011) from University of Sargodha and Master of Philosophy in Pharmaceutical Chemistry (2014) from Bahauddin Zakariya University, Pakistan. After M.Phil, he worked as Research Assistant (2013-16) at Department of Chemistry, Lahore University of Management Sciences where he developed nano-pharmaceuticals for drug delivery and to improve the pharmacokinetic profiles of hydrophobic drugs. With extensive research experience in the synthesis of pharmaceutical nanomaterials, in vivo modelling, pharmacokinetics and protein misfolding diseases, Dr. Javed has published >50 research publications in prestigious journals like Nature Communications, Nano Letter, Advanced Science and Small.

Research Impacts

Dr. Javed's research focuses on understanding the pathophysiology of protein misfolding diseases, i.e., Alzheimer’s, Parkinson’s and Type-2-Diabetes and the biochemical interference from gut-bacteria. He also uses functional amyloids, as beta-lactoglobulin and casein from milk, to craft nanomedicine against amyloid diseases. He has developed in vivo model systems, using zebrafish, to study the pathogenesis of amyloid diseases as well as interaction, fate and mitigation profiling of nanomaterials. Dr. Javed's is also interested on biofilm component of bacterial biofilm (like FapC from Pseudomonas and CsgA from E. coli) and Gut-Brain axis to unravel the associations of gut microbiome with the development of amyloid based neurological disorders.

Publications

  • Andrikopoulos, Nicholas, Song, Zhiyuan, Wan, Xulin, Douek, Alon M., Javed, Ibrahim, Fu, Changkui, Xing, Yanting, Xin, Fangyun, Li, Yuhuan, Kakinen, Aleksandr, Koppel, Kairi, Qiao, Ruirui, Whittaker, Andrew K., Kaslin, Jan, Davis, Thomas P., Song, Yang, Ding, Feng and Ke, Pu Chun (2021). Inhibition of amyloid aggregation and toxicity with Janus iron oxide nanoparticles. Chemistry of Materials, 33 (16) acs.chemmater.1c01947, 6484-6500. doi: 10.1021/acs.chemmater.1c01947

  • Bondarenko, Olesja, Mortimer, Monika, Kahru, Anne, Feliu, Neus, Javed, Ibrahim, Kakinen, Aleksandr, Lin, Sijie, Xia, Tian, Song, Yang, Davis, Thomas P., Lynch, Iseult, Parak, Wolfgang J., Leong, David Tai, Ke, Pu Chun, Chen, Chunying and Zhao, Yuliang (2021). Nanotoxicology and nanomedicine: The Yin and Yang of nano-bio interactions for the new decade. Nano Today, 39 101184, 101184. doi: 10.1016/j.nantod.2021.101184

  • Khan, Muhammad Tariq, Nadeem, Humaira, Sheikh, Ahmed Sadiq, Malik, Nadia Shamshad, Rizwan, Muhammad, Imran, Muhammad, Javed, Ibrahim, Munir, Muhammad Usman, Khan, Arif-Ullah, Syed, Akash and Abbas, Muzaffar (2021). Amino acid derivatives of 2-Mercaptobenzimidazoles suppress cytokines at the site of inflammation and block gastric H+/K+ ATPase. Pakistan Journal of Pharmaceutical Sciences, 34 (3), 1157-1163. doi: 10.36721/PJPS.2021.34.3.SUP.1157-1163.1

View all Publications

Publications

Book Chapter

  • Peng, Guotao, Zil-e-Huma, , Umair, Muhammad, Hussain, Irshad and Javed, Ibrahim (2020). Nanosilver at the interface of biomedical applications, toxicology, and synthetic strategies. Metal Nanoparticles for Drug Delivery and Diagnostic Applications. (pp. 119-139) edited by Muhammad Raza Shah, Muhammad Imran and Shafi Ullah. Amsterdam, Netherlands: Elsevier. doi: 10.1016/b978-0-12-816960-5.00008-2

Journal Article